JPH07103127B2 - チエノートリアゾロ―ジアゼピン誘導体、その製造法及びそれを含有する抗喘息、抗アレルギー剤 - Google Patents

チエノートリアゾロ―ジアゼピン誘導体、その製造法及びそれを含有する抗喘息、抗アレルギー剤

Info

Publication number
JPH07103127B2
JPH07103127B2 JP2073582A JP7358290A JPH07103127B2 JP H07103127 B2 JPH07103127 B2 JP H07103127B2 JP 2073582 A JP2073582 A JP 2073582A JP 7358290 A JP7358290 A JP 7358290A JP H07103127 B2 JPH07103127 B2 JP H07103127B2
Authority
JP
Japan
Prior art keywords
group
triazolo
compound
diazepine
thieno
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2073582A
Other languages
English (en)
Japanese (ja)
Other versions
JPH02289582A (ja
Inventor
ブラク，ピエール
エサヌ，アンドレ
ローラン，ジヤン‐ピエール
ローラン，アラン
Original Assignee
ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス）
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス） filed Critical ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーシヨン・シヤンテイフイツク・（エス．セー．エール．アー．エス）
Publication of JPH02289582A publication Critical patent/JPH02289582A/ja
Publication of JPH07103127B2 publication Critical patent/JPH07103127B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2073582A 1989-03-31 1990-03-26 チエノートリアゾロ―ジアゼピン誘導体、その製造法及びそれを含有する抗喘息、抗アレルギー剤 Expired - Lifetime JPH07103127B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8907256.5 1989-03-31
GB898907256A GB8907256D0 (en) 1989-03-31 1989-03-31 New derivatives of hetrazepine as anti-asthmatic anti-allergic and gastro-intestinal protectors

Publications (2)

Publication Number Publication Date
JPH02289582A JPH02289582A (ja) 1990-11-29
JPH07103127B2 true JPH07103127B2 (ja) 1995-11-08

Family

ID=10654231

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2073582A Expired - Lifetime JPH07103127B2 (ja) 1989-03-31 1990-03-26 チエノートリアゾロ―ジアゼピン誘導体、その製造法及びそれを含有する抗喘息、抗アレルギー剤

Country Status (30)

Country Link
US (1) US5492906A (enExample)
JP (1) JPH07103127B2 (enExample)
KR (1) KR900014396A (enExample)
AT (1) AT394561B (enExample)
AU (1) AU622007B2 (enExample)
BE (1) BE1003699A3 (enExample)
CA (1) CA2013518C (enExample)
CH (1) CH680365A5 (enExample)
DE (1) DE4010316C2 (enExample)
DK (1) DK80890A (enExample)
ES (1) ES2019243A6 (enExample)
FI (1) FI95036C (enExample)
FR (2) FR2645022B1 (enExample)
GB (2) GB8907256D0 (enExample)
GR (1) GR1000394B (enExample)
HK (1) HK95192A (enExample)
IE (1) IE64564B1 (enExample)
IN (1) IN174015B (enExample)
IT (1) IT1240350B (enExample)
LU (1) LU87710A1 (enExample)
MA (1) MA21790A1 (enExample)
MY (1) MY105538A (enExample)
NL (1) NL194827C (enExample)
NO (1) NO173784C (enExample)
NZ (1) NZ233011A (enExample)
OA (1) OA09442A (enExample)
PT (1) PT93629B (enExample)
SE (1) SE505417C2 (enExample)
TN (1) TNSN90042A1 (enExample)
ZA (1) ZA901765B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
US5304553A (en) * 1988-10-31 1994-04-19 Eisai Co., Ltd. 1,4-diazepine derivative and its pharmaceutical use
US5221671A (en) * 1988-10-31 1993-06-22 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
US5382579A (en) * 1988-10-31 1995-01-17 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
FI101989B (fi) * 1996-11-22 1998-09-30 Stora Enso Oyj Menetelmät neste- ja kaasutiiviin pakkauskartongin sekä pakkauksen val mistamiseksi sekä menetelmien mukaisesti valmistetut tuotteet
CA2294139A1 (en) 1997-06-25 1998-12-30 Nikken Chemicals Co., Ltd. Triazolo-1,4-diazepine compounds and medicinal composition containing the same
FR2779652B1 (fr) 1998-06-15 2001-06-08 Sod Conseils Rech Applic Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
WO2001083440A2 (en) * 2000-04-28 2001-11-08 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis and use of thienotriazolodiazepines
CN1812983A (zh) * 2003-05-30 2006-08-02 兰贝克赛实验室有限公司 取代的吡咯衍生物及其作为hmg－co抑制剂的用途
SG166829A1 (en) * 2005-11-08 2010-12-29 Ranbaxy Lab Ltd Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
WO2008020314A2 (en) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Statin stabilizing dosage formulations
WO2008010087A2 (en) * 2006-07-14 2008-01-24 Ranbaxy Laboratories Limited Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof
KR101675984B1 (ko) * 2015-02-23 2016-11-14 한양대학교 에리카산학협력단 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
US5028603A (en) * 1987-06-08 1991-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Ester-substituted thienotriazolodiazepine compounds and pharmaceutical uses thereof
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
NL9000627A (nl) * 1990-03-29 1991-10-16 Scras Werkwijze ter bereiding van nieuwe thienotriazolo-diazepines.

Also Published As

Publication number Publication date
US5492906A (en) 1996-02-20
TNSN90042A1 (fr) 1991-03-05
FR2645153B1 (fr) 1992-04-17
NO901070D0 (no) 1990-03-07
GR900100165A (en) 1990-07-31
NO901070L (no) 1990-10-01
ES2019243A6 (es) 1991-06-01
NO173784B (no) 1993-10-25
GR1000394B (el) 1992-06-30
LU87710A1 (fr) 1990-07-24
FR2645022B1 (fr) 1992-04-17
FI95036C (fi) 1995-12-11
DK80890A (da) 1990-10-01
SE9000871D0 (sv) 1990-03-12
GB8907256D0 (en) 1989-05-17
CH680365A5 (enExample) 1992-08-14
FI901605A0 (fi) 1990-03-30
CA2013518A1 (en) 1990-09-30
AU622007B2 (en) 1992-03-26
IE900806L (en) 1990-09-30
FI95036B (fi) 1995-08-31
NL194827C (nl) 2003-04-03
NL194827B (nl) 2002-12-02
OA09442A (fr) 1992-10-15
NZ233011A (en) 1991-02-26
MY105538A (en) 1994-10-31
AT394561B (de) 1992-05-11
PT93629B (pt) 1996-07-31
CA2013518C (en) 2004-02-24
ZA901765B (en) 1990-12-28
MA21790A1 (fr) 1990-10-01
DE4010316C2 (de) 2003-05-28
SE505417C2 (sv) 1997-08-25
DK80890D0 (da) 1990-03-30
GB9007000D0 (en) 1990-05-30
DE4010316A1 (de) 1990-10-04
NO173784C (no) 1994-02-02
IT9019884A1 (it) 1991-09-30
JPH02289582A (ja) 1990-11-29
IT9019884A0 (it) 1990-03-30
FR2645022A1 (fr) 1990-10-05
SE9000871L (sv) 1990-10-01
FR2645153A1 (fr) 1990-10-05
IT1240350B (it) 1993-12-07
NL9000626A (nl) 1990-10-16
BE1003699A3 (fr) 1992-05-26
GB2229723B (en) 1992-07-01
IN174015B (enExample) 1994-08-27
KR900014396A (ko) 1990-10-23
ATA56790A (de) 1991-10-15
AU5242590A (en) 1990-11-01
IE64564B1 (en) 1996-08-23
HK95192A (en) 1992-12-04
PT93629A (pt) 1990-11-20
GB2229723A (en) 1990-10-03

Similar Documents

Publication Publication Date Title
DE2249644A1 (de) Neue organische verbindungen und verfahren zu deren herstellung
US5492906A (en) Derivatives of thieno-triazolo-diazepine and therapeutic compositions containing them
JPS5930713B2 (ja) 新規な置換６−アリ−ル−４Ｈ−Ｓ−トリアゾロ−〔３，４Ｃ〕−チエノ−〔２，３ｅ〕−１，４−ジアゼピン類の製造方法
JPS627914B2 (enExample)
JPH06104668B2 (ja) チエノ‐トリアゾロ‐ジアゼピンのチオメチル誘導体、その製造方法及びそれを含有する医薬組成物
JPH04273878A (ja) 複素環式化合物及びその製法
JPS6365673B2 (enExample)
JPH06104667B2 (ja) チエノ‐トリアゾロ‐ジアゼピンのスルホニル誘導体、その製造方法及びそれを含有する医薬組成物
JPH0686458B2 (ja) 新規なチェノ‐トリアゾロ‐ジアゼピン誘導体の製造法
US5527908A (en) Pyrazolothiazolopyrimidine derivatives
JPS6228146B2 (enExample)
CA1049017A (en) Pyrrolo (3,4-b) pyridines and methods for their preparation
CA2013516C (en) Preparation process of new thieno-triazolo-diazepine
JPH06102665B2 (ja) チエノ‐トリアゾロ‐ジアゼピン誘導体の製造法
AT394562B (de) Verfahren zur herstellung neuer thieno-triazolodiazepine
GB2242427A (en) Preparation of thieno-triazolo-diazepine derivatives
DK167281B1 (da) Analogifremgangsmaade til fremstilling af terapeutisk aktive imidazooe1,5-aaaoe1,4aadiazepin-forbindelser eller farmaceutisk acceptable salte deraf
JPS6023116B2 (ja) ジアゼピン化合物の製造方法
JPS6247186B2 (enExample)
IE900807A1 (en) Preparation of thieno-triazolo-diazepine derivatives
FR2660311A1 (fr) Procede de preparation des nouveaux derives de la thieno-triazolo-diazepine.
GB2138423A (en) Intermediates which may be used for the preparation of 4h-1,4-benzothiozine derivatives
SE507189C3 (sv) Framstaellningsfoerfarande foer nya tieno-triazolo-diazepin-foereningar
NO173504B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tieno-triazolo-diazepin-derivater
PL97987B1 (pl) Sposob wytwarzania nowych kwasow lub estrow/4,5-b/-pirymido-(3h)-chinolinonow-4