BRPI0618379A2 - processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico - Google Patents

processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico Download PDF

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Publication number
BRPI0618379A2
BRPI0618379A2 BRPI0618379-4A BRPI0618379A BRPI0618379A2 BR PI0618379 A2 BRPI0618379 A2 BR PI0618379A2 BR PI0618379 A BRPI0618379 A BR PI0618379A BR PI0618379 A2 BRPI0618379 A2 BR PI0618379A2
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fluorophenyl
carbonyl
isopropyl
phenyl
hydroxymethylphenylamino
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BRPI0618379-4A
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English (en)
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Vijay Kaul
Chand Gyan Yadav
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Ranbaxy Lab Ltd
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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

PROCESSO PARA PREPARAçãO DO HEMI-SAL DE CáLCIO DO áCIDO (3R, 5R) -7- [2- (4-FLUOROFENIL) -5-ISOPROPIL-3-FENIL-4- [(4- HIDROXIMETILFENILAMINO) CARBONIL] -PIRROL-1-IL] -3, 5-DIIDROXI HEPTANóICO. A presente invenção se refere a processos para a produção do hemi-sal de cálcio do ácido (3R,5R)-7-[2-(4-fluorofenil)-5-isopropil-3-fenhl-4-[ (4-hidroximetilfenil amino) carbonil]-pirrol-1-il]-3, 5-diidroxiheptanóico.
BRPI0618379-4A 2005-11-08 2006-11-07 processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico BRPI0618379A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN2964DE2005 2005-11-08
IN2967DE2005 2005-11-08
IN3033DE2005 2005-11-14
PCT/IB2006/054154 WO2007054896A1 (en) 2005-11-08 2006-11-07 Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt

Publications (1)

Publication Number Publication Date
BRPI0618379A2 true BRPI0618379A2 (pt) 2011-08-30

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Family Applications (3)

Application Number Title Priority Date Filing Date
BRPI0618379-4A BRPI0618379A2 (pt) 2005-11-08 2006-11-07 processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico
BRPI0618381-6A BRPI0618381A2 (pt) 2005-11-08 2006-11-08 processo para a preparação do hemi-sal de cálcio do ácido (3r, 5r) -7-[2-(4-fluorofenil) -5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico
BRPI0618380-8A BRPI0618380A2 (pt) 2005-11-08 2006-11-08 combinação farmacêutica e seu uso

Family Applications After (2)

Application Number Title Priority Date Filing Date
BRPI0618381-6A BRPI0618381A2 (pt) 2005-11-08 2006-11-08 processo para a preparação do hemi-sal de cálcio do ácido (3r, 5r) -7-[2-(4-fluorofenil) -5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico
BRPI0618380-8A BRPI0618380A2 (pt) 2005-11-08 2006-11-08 combinação farmacêutica e seu uso

Country Status (13)

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US (5) US8026377B2 (pt)
EP (3) EP1948599A1 (pt)
JP (3) JP2009514851A (pt)
KR (3) KR101329112B1 (pt)
CN (1) CN102526029A (pt)
AU (3) AU2006313430B2 (pt)
BR (3) BRPI0618379A2 (pt)
CA (3) CA2627599A1 (pt)
IL (1) IL191203A0 (pt)
MY (1) MY147450A (pt)
NZ (1) NZ567738A (pt)
SG (1) SG166829A1 (pt)
WO (3) WO2007054896A1 (pt)

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