AT296986B - Verfahren zur Herstellung von neuen α-Halogenphenoxy-isobutyroyl-β-nicotinoyl-glykolen - Google Patents
Verfahren zur Herstellung von neuen α-Halogenphenoxy-isobutyroyl-β-nicotinoyl-glykolenInfo
- Publication number
- AT296986B AT296986B AT616070A AT616070A AT296986B AT 296986 B AT296986 B AT 296986B AT 616070 A AT616070 A AT 616070A AT 616070 A AT616070 A AT 616070A AT 296986 B AT296986 B AT 296986B
- Authority
- AT
- Austria
- Prior art keywords
- isobutyroyl
- halophenoxy
- nicotinoyl
- glycols
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67B—APPLYING CLOSURE MEMBERS TO BOTTLES JARS, OR SIMILAR CONTAINERS; OPENING CLOSED CONTAINERS
- B67B1/00—Closing bottles, jars or similar containers by applying stoppers
- B67B1/08—Securing stoppers, e.g. swing stoppers, which are held in position by associated pressure-applying means coacting with the bottle neck
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1941217A DE1941217C3 (de) | 1969-08-13 | 1969-08-13 | Alpha- eckige Klamer auf 2-(p-Chlorphenoxy)-isobutyryril eckige Klammer zu-beta-nicotinoylglykolester und Verfahren zu seiner Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT296986B true AT296986B (de) | 1972-03-10 |
Family
ID=5742695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT616070A AT296986B (de) | 1969-08-13 | 1970-07-07 | Verfahren zur Herstellung von neuen α-Halogenphenoxy-isobutyroyl-β-nicotinoyl-glykolen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3723446A (de) |
| AT (1) | AT296986B (de) |
| BE (1) | BE753639A (de) |
| CH (1) | CH534156A (de) |
| ES (1) | ES382339A1 (de) |
| FR (1) | FR2068494B1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2270878B1 (de) * | 1974-05-15 | 1978-02-03 | Fabre Sa Pierre | |
| US4051143A (en) * | 1974-09-05 | 1977-09-27 | Merz & Co. | Process for the production of α-[2-(p-chlorophenoxy)-isobutyryl]-β-nicotinoyl glycol ester |
| BE826867A (fr) * | 1974-11-20 | 1975-07-16 | Medicament hypolipidemiant et hydrocholesterolemiant | |
| ES438246A1 (es) * | 1975-06-04 | 1977-01-16 | Alter Sa | Un procedimiento de preparacion del glicol 2-(p-clorofenoci)-2-metilpropinato nicotinato. |
| US6083497A (en) * | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| EP1658283A2 (de) * | 2003-05-30 | 2006-05-24 | Ranbaxy Laboratories, Ltd. | Substituierte pyrrolderivate und deren verwendung als hmg-co-inhibitoren |
| BRPI0618379A2 (pt) * | 2005-11-08 | 2011-08-30 | Ranbaxy Lab Ltd | processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico |
| TW200744583A (en) * | 2006-03-14 | 2007-12-16 | Ranbaxy Lab Ltd | Statin stabilizing dosage formulations |
| BRPI0714361A2 (pt) * | 2006-07-14 | 2013-03-26 | Ranbaxy Lab Ltd | polimorfo cristalino, composiÇço farmacÊutica contendo o mesmo, mÉtodo para sua preparaÇço e mÉtodo de tratamento |
| CN101555224B (zh) * | 2009-04-15 | 2012-01-18 | 大道隆达（北京）医药科技发展有限公司 | 一种依托贝特的制备方法 |
| BR112017016766B1 (pt) | 2015-02-06 | 2023-11-07 | Intercept Pharmaceuticals, Inc | Composição compreendendo um agonista fxr e fibrato, bem como uso para tratar doença hepática colestática |
| US20220226350A1 (en) | 2019-05-30 | 2022-07-21 | Intercept Pharmaceuticals, Inc. | Pharmaceutical compositions comprising a fxr agonist and a fibrate for use in the treatment of cholestatic liver disease |
-
1970
- 1970-07-07 AT AT616070A patent/AT296986B/de active
- 1970-07-17 CH CH1094770A patent/CH534156A/de not_active IP Right Cessation
- 1970-07-17 BE BE753639D patent/BE753639A/xx not_active IP Right Cessation
- 1970-07-31 ES ES382339A patent/ES382339A1/es not_active Expired
- 1970-08-12 US US00063344A patent/US3723446A/en not_active Expired - Lifetime
- 1970-08-13 FR FR7029878A patent/FR2068494B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE753639A (de) | 1970-12-31 |
| ES382339A1 (es) | 1973-07-01 |
| US3723446A (en) | 1973-03-27 |
| FR2068494A1 (de) | 1971-08-27 |
| FR2068494B1 (de) | 1974-08-30 |
| CH534156A (de) | 1973-02-28 |
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