JPH0680079B2 - ポリペプチド - Google Patents
ポリペプチドInfo
- Publication number
- JPH0680079B2 JPH0680079B2 JP59236076A JP23607684A JPH0680079B2 JP H0680079 B2 JPH0680079 B2 JP H0680079B2 JP 59236076 A JP59236076 A JP 59236076A JP 23607684 A JP23607684 A JP 23607684A JP H0680079 B2 JPH0680079 B2 JP H0680079B2
- Authority
- JP
- Japan
- Prior art keywords
- arg
- leu
- formula
- group
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/675—Beta-endorphins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59236076A JPH0680079B2 (ja) | 1984-11-09 | 1984-11-09 | ポリペプチド |
| FI854227A FI92935C (fi) | 1984-11-09 | 1985-10-28 | Menetelmä analgeettisena aineena käyttökelpoisten polypeptidien valmistamiseksi |
| CN85109722A CN1029684C (zh) | 1984-11-09 | 1985-11-02 | 一种新肽及其制造方法 |
| IL76924A IL76924A (en) | 1984-11-09 | 1985-11-04 | Polypeptides,process for the preparation thereof and pharmaceutical compositions containing the same |
| KR8508213A KR880000765B1 (en) | 1984-11-09 | 1985-11-04 | Process for the preparation of polypetide |
| PH33004A PH23847A (en) | 1984-11-09 | 1985-11-04 | Polypeptide |
| ZA858456A ZA858456B (en) | 1984-11-09 | 1985-11-04 | Polypeptide |
| AU49389/85A AU588837B2 (en) | 1984-11-09 | 1985-11-06 | Polypeptide |
| SU3974503A SU1433415A3 (ru) | 1984-11-09 | 1985-11-06 | Способ получени пептидов |
| PT81441A PT81441B (pt) | 1984-11-09 | 1985-11-06 | Processo para a prepafracao de novos polipeptideos, utilizaveis como analgesicos |
| HU854270A HU203563B (en) | 1984-11-09 | 1985-11-06 | Process for producing opioid-polypeptides and pharmaceutical compositions containing them |
| NO854435A NO169347C (no) | 1984-11-09 | 1985-11-07 | Analogifremgangsmaate for fremstilling av terapeutisk aktive polypeptider |
| GR852689A GR852689B (forum.php) | 1984-11-09 | 1985-11-07 | |
| ES548667A ES8800272A1 (es) | 1984-11-09 | 1985-11-07 | Un procedimiento para la preparacion de polipeptidos. |
| DK513385A DK171300B1 (da) | 1984-11-09 | 1985-11-07 | Polypeptider, fremgangsmåder til deres fremstilling og analgetikum indeholdende et sådant polypeptid |
| DE3588095T DE3588095T2 (de) | 1984-11-09 | 1985-11-08 | Polypeptid, dessen Verfahren zur Herstellung und dieses enthaltende pharmazeutische Zusammensetzung und deren Benutzung |
| EP94107769A EP0614913A3 (en) | 1984-11-09 | 1985-11-08 | Dynorphin derivatives. |
| AT85114226T ATE135712T1 (de) | 1984-11-09 | 1985-11-08 | Polypeptid, dessen verfahren zur herstellung und dieses enthaltende pharmazeutische zusammensetzung und deren benutzung |
| CA000494974A CA1267997A (en) | 1984-11-09 | 1985-11-08 | Polypeptides and process for the production thereof |
| NZ214122A NZ214122A (en) | 1984-11-09 | 1985-11-08 | Analgesic dynorphin-like hepta and octa and nona and deca peptides |
| EP85114226A EP0181001B1 (en) | 1984-11-09 | 1985-11-08 | Polypeptide, a process for preparing the same, a pharmaceutical composition containing said polypeptide as well as the use thereof |
| US06/796,390 US4707468A (en) | 1984-11-09 | 1985-11-08 | Polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59236076A JPH0680079B2 (ja) | 1984-11-09 | 1984-11-09 | ポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61115097A JPS61115097A (ja) | 1986-06-02 |
| JPH0680079B2 true JPH0680079B2 (ja) | 1994-10-12 |
Family
ID=16995360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59236076A Expired - Lifetime JPH0680079B2 (ja) | 1984-11-09 | 1984-11-09 | ポリペプチド |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4707468A (forum.php) |
| EP (2) | EP0181001B1 (forum.php) |
| JP (1) | JPH0680079B2 (forum.php) |
| KR (1) | KR880000765B1 (forum.php) |
| CN (1) | CN1029684C (forum.php) |
| AT (1) | ATE135712T1 (forum.php) |
| AU (1) | AU588837B2 (forum.php) |
| CA (1) | CA1267997A (forum.php) |
| DE (1) | DE3588095T2 (forum.php) |
| DK (1) | DK171300B1 (forum.php) |
| ES (1) | ES8800272A1 (forum.php) |
| FI (1) | FI92935C (forum.php) |
| GR (1) | GR852689B (forum.php) |
| HU (1) | HU203563B (forum.php) |
| IL (1) | IL76924A (forum.php) |
| NO (1) | NO169347C (forum.php) |
| NZ (1) | NZ214122A (forum.php) |
| PH (1) | PH23847A (forum.php) |
| PT (1) | PT81441B (forum.php) |
| SU (1) | SU1433415A3 (forum.php) |
| ZA (1) | ZA858456B (forum.php) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020510005A (ja) * | 2017-06-14 | 2020-04-02 | バイオソリューション カンパニー・リミテッドＢｉｏ Ｓｏｌｕｔｉｏｎ Ｃｏ Ｌｔｄ | 物質ｐを含むしわの改善または抗炎症化粧料組成物 |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2673376A1 (fr) * | 1991-03-01 | 1992-09-04 | Lefesvre Andre | Composition pharmaceutique pour le traitement des tumeurs de kaposi. |
| US5817628A (en) * | 1992-12-02 | 1998-10-06 | The Rockefeller University | Dynorphin a suppression of natural killer cell activity |
| SE9401596D0 (sv) * | 1994-05-06 | 1994-05-06 | Astra Ab | New compounds |
| JP3385147B2 (ja) * | 1996-01-31 | 2003-03-10 | ユニ・チャーム株式会社 | 男性用尿とり袋 |
| AU3499997A (en) * | 1996-06-24 | 1998-01-14 | Rockefeller University, The | Method of using ligands of the kappa opioid receptor |
| WO1999046283A1 (en) * | 1998-03-09 | 1999-09-16 | Zealand Pharmaceuticals A/S | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
| US6232287B1 (en) * | 1998-03-13 | 2001-05-15 | The Burnham Institute | Molecules that home to various selected organs or tissues |
| IL137820A (en) * | 2000-08-10 | 2009-06-15 | S I S Shulov Inst For Science | Pharmaceutical composition for topical administration comprising an analgesic peptide |
| US6884910B2 (en) * | 2000-08-25 | 2005-04-26 | Research Corporation Technologies, Inc. | Uses for amino acid anticonvulsants |
| PT1243262E (pt) * | 2001-03-20 | 2006-10-31 | Sanol Arznei Schwarz Gmbh | Nova utilizacao de uma classe de compostos peptideos para o tratamento da dor inflamatoria nao neuropatica |
| ATE228358T1 (de) * | 2001-03-21 | 2002-12-15 | Sanol Arznei Schwarz Gmbh | Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen |
| US7491702B2 (en) * | 2001-04-18 | 2009-02-17 | The Open University | Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same |
| US7622446B2 (en) * | 2001-04-18 | 2009-11-24 | The Open University | Polypeptides, derivatives and uses thereof |
| MXPA06011937A (es) | 2004-04-16 | 2007-01-26 | Sanol Arznei Schwarz Gmbh | Uso de compuestos peptidicos para la profilaxis y el tratamiento de dolor de cabeza cronico. |
| CA2573125A1 (en) * | 2004-08-27 | 2006-03-02 | Schwarz Pharma Ag | Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain |
| US20070048372A1 (en) * | 2005-08-18 | 2007-03-01 | Srz Properties, Inc. | Method for treating non-inflammatory osteoarthritic pain |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
| GB2432586B (en) * | 2005-11-25 | 2010-01-13 | Univ Open | Treatment of neurodegenerative disorders |
| MX2008016000A (es) | 2006-06-15 | 2009-03-05 | Sanol Arznei Schwarz Gmbh | Composicion farmaceutica con efecto anticonvulsivante sinergistico. |
| JP2010539065A (ja) * | 2007-09-11 | 2010-12-16 | モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト | 治療剤としてのペプチドの使用 |
| WO2009033758A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of the peptide phpfhffvyk as therapeutic agent |
| TW201920234A (zh) | 2017-09-11 | 2019-06-01 | 美商領導醫療有限公司 | 類鴉片促效劑肽及其用途 |
| CA3188556A1 (en) * | 2020-07-01 | 2022-01-06 | PreveCeutical Medical Inc. | Peptides and uses thereof |
| RU2760133C1 (ru) * | 2021-04-22 | 2021-11-22 | Федеральное государственное бюджетное учреждение науки "Научный центр биомедицинских технологий Федерального медико-биологического агентства". | Амиды гептапептида для лечения HMGB1-зависимых заболеваний |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2338925A1 (fr) * | 1976-01-26 | 1977-08-19 | Wellcome Found | Nouveaux peptides et medicament contenant ces substances |
| US4254106A (en) * | 1976-01-26 | 1981-03-03 | Burroughs Wellcome Co. | Biologically active amides |
| US4123523A (en) * | 1976-06-21 | 1978-10-31 | Imperial Chemical Industries Limited | Analgesic and sedative polypeptides |
| US4371463A (en) * | 1977-02-17 | 1983-02-01 | The United States Of America As Represented By The Department Of Health And Human Services | Enzyme-resistant opiate pentapeptides |
| US4081434A (en) * | 1977-03-11 | 1978-03-28 | Hoffmann-La Roche Inc. | Novel analogs of β-endorphin |
| US4139504A (en) * | 1977-06-16 | 1979-02-13 | Coy David Howard | Novel nonapeptides, intermediates therefor, and compositions and methods employing said nonapeptides |
| US4127533A (en) * | 1977-06-16 | 1978-11-28 | Coy David Howard | Novel octapeptides, intermediates therefor, and compositions and methods employing said octapeptides |
| GB1604850A (en) * | 1977-11-24 | 1981-12-16 | Wellcome Found | Biologically active peptides |
| US4148786A (en) * | 1978-06-26 | 1979-04-10 | American Home Products Corporation | Analgesic polypeptide |
| US4178284A (en) * | 1978-12-11 | 1979-12-11 | American Home Products Corporation | Octapeptides |
| DE2936099A1 (de) * | 1979-09-06 | 1981-04-02 | Victor Dipl.- Chem. 8000 München Brantl | Pharmakologisch aktive peptide |
| EP0044451B1 (en) * | 1980-07-17 | 1984-04-18 | Sandoz Ag | Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use |
| JPS57134451A (en) * | 1981-02-13 | 1982-08-19 | Suntory Ltd | Peptide opioide |
| DE3274798D1 (en) * | 1981-10-05 | 1987-02-05 | Nicholas P Plotnikoff | Process for using endorphins as antitumour agents |
| US4462941A (en) * | 1982-06-10 | 1984-07-31 | The Regents Of The University Of California | Dynorphin amide analogs |
| JPS59141547A (ja) * | 1983-02-01 | 1984-08-14 | Eisai Co Ltd | 鎮痛作用を有する新規ペプタイドおよび製法 |
| US4518711A (en) * | 1983-05-16 | 1985-05-21 | Gibson-Stephens Institute | Conformationally constrained cyclic enkephalin analogs with delta receptor specificity |
-
1984
- 1984-11-09 JP JP59236076A patent/JPH0680079B2/ja not_active Expired - Lifetime
-
1985
- 1985-10-28 FI FI854227A patent/FI92935C/fi not_active IP Right Cessation
- 1985-11-02 CN CN85109722A patent/CN1029684C/zh not_active Expired - Lifetime
- 1985-11-04 PH PH33004A patent/PH23847A/en unknown
- 1985-11-04 ZA ZA858456A patent/ZA858456B/xx unknown
- 1985-11-04 IL IL76924A patent/IL76924A/xx not_active IP Right Cessation
- 1985-11-04 KR KR8508213A patent/KR880000765B1/ko not_active Expired
- 1985-11-06 HU HU854270A patent/HU203563B/hu not_active IP Right Cessation
- 1985-11-06 SU SU3974503A patent/SU1433415A3/ru active
- 1985-11-06 AU AU49389/85A patent/AU588837B2/en not_active Ceased
- 1985-11-06 PT PT81441A patent/PT81441B/pt not_active IP Right Cessation
- 1985-11-07 ES ES548667A patent/ES8800272A1/es not_active Expired
- 1985-11-07 DK DK513385A patent/DK171300B1/da not_active IP Right Cessation
- 1985-11-07 NO NO854435A patent/NO169347C/no not_active IP Right Cessation
- 1985-11-07 GR GR852689A patent/GR852689B/el unknown
- 1985-11-08 US US06/796,390 patent/US4707468A/en not_active Expired - Lifetime
- 1985-11-08 EP EP85114226A patent/EP0181001B1/en not_active Expired - Lifetime
- 1985-11-08 EP EP94107769A patent/EP0614913A3/en not_active Withdrawn
- 1985-11-08 AT AT85114226T patent/ATE135712T1/de not_active IP Right Cessation
- 1985-11-08 DE DE3588095T patent/DE3588095T2/de not_active Expired - Fee Related
- 1985-11-08 CA CA000494974A patent/CA1267997A/en not_active Expired - Fee Related
- 1985-11-08 NZ NZ214122A patent/NZ214122A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020510005A (ja) * | 2017-06-14 | 2020-04-02 | バイオソリューション カンパニー・リミテッドＢｉｏ Ｓｏｌｕｔｉｏｎ Ｃｏ Ｌｔｄ | 物質ｐを含むしわの改善または抗炎症化粧料組成物 |
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