DE3588095T2 - Polypeptid, dessen Verfahren zur Herstellung und dieses enthaltende pharmazeutische Zusammensetzung und deren Benutzung - Google Patents

Polypeptid, dessen Verfahren zur Herstellung und dieses enthaltende pharmazeutische Zusammensetzung und deren Benutzung

Info

Publication number
DE3588095T2
DE3588095T2 DE3588095T DE3588095T DE3588095T2 DE 3588095 T2 DE3588095 T2 DE 3588095T2 DE 3588095 T DE3588095 T DE 3588095T DE 3588095 T DE3588095 T DE 3588095T DE 3588095 T2 DE3588095 T2 DE 3588095T2
Authority
DE
Germany
Prior art keywords
pharmaceutical composition
composition containing
polypeptide
production process
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3588095T
Other languages
English (en)
Other versions
DE3588095D1 (de
Inventor
Hiroshi Yoshino
Yutaka Tsuchiya
Takeru Kaneko
Takahiro Nakazawa
Masuhiro Ikeda
Shin Araki
Kiyomi Yamatsu
Shinro Tachibana
Yoshihiro Arakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DE3588095D1 publication Critical patent/DE3588095D1/de
Publication of DE3588095T2 publication Critical patent/DE3588095T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675—Beta-endorphins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3588095T 1984-11-09 1985-11-08 Polypeptid, dessen Verfahren zur Herstellung und dieses enthaltende pharmazeutische Zusammensetzung und deren Benutzung Expired - Fee Related DE3588095T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59236076A JPH0680079B2 (ja) 1984-11-09 1984-11-09 ポリペプチド

Publications (2)

Publication Number Publication Date
DE3588095D1 DE3588095D1 (de) 1996-04-25
DE3588095T2 true DE3588095T2 (de) 1996-09-19

Family

ID=16995360

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3588095T Expired - Fee Related DE3588095T2 (de) 1984-11-09 1985-11-08 Polypeptid, dessen Verfahren zur Herstellung und dieses enthaltende pharmazeutische Zusammensetzung und deren Benutzung

Country Status (21)

Country Link
US (1) US4707468A (de)
EP (2) EP0614913A3 (de)
JP (1) JPH0680079B2 (de)
KR (1) KR880000765B1 (de)
CN (1) CN1029684C (de)
AT (1) ATE135712T1 (de)
AU (1) AU588837B2 (de)
CA (1) CA1267997A (de)
DE (1) DE3588095T2 (de)
DK (1) DK171300B1 (de)
ES (1) ES8800272A1 (de)
FI (1) FI92935C (de)
GR (1) GR852689B (de)
HU (1) HU203563B (de)
IL (1) IL76924A (de)
NO (1) NO169347C (de)
NZ (1) NZ214122A (de)
PH (1) PH23847A (de)
PT (1) PT81441B (de)
SU (1) SU1433415A3 (de)
ZA (1) ZA858456B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2673376A1 (fr) * 1991-03-01 1992-09-04 Lefesvre Andre Composition pharmaceutique pour le traitement des tumeurs de kaposi.
US5817628A (en) * 1992-12-02 1998-10-06 The Rockefeller University Dynorphin a suppression of natural killer cell activity
SE9401596D0 (sv) * 1994-05-06 1994-05-06 Astra Ab New compounds
JP3385147B2 (ja) * 1996-01-31 2003-03-10 ユニ・チャーム株式会社 男性用尿とり袋
WO1997049422A1 (en) * 1996-06-24 1997-12-31 The Rockefeller University Method of using ligands of the kappa opioid receptor
CA2321026A1 (en) * 1998-03-09 1999-09-16 Zealand Pharmaceuticals A/S Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
US6232287B1 (en) * 1998-03-13 2001-05-15 The Burnham Institute Molecules that home to various selected organs or tissues
IL137820A (en) * 2000-08-10 2009-06-15 S I S Shulov Inst For Science Pharmaceutical composition for topical administration comprising an analgesic peptide
CA2740815C (en) * 2000-08-25 2014-03-18 Research Corporation Technologies, Inc. New uses for amino acid anticonvulsants
DK1243262T3 (da) * 2001-03-20 2006-10-02 Sanol Arznei Schwarz Gmbh Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter
EP1243263B1 (de) * 2001-03-21 2002-11-27 Schwarz Pharma Ag Neue Verwendung einer Klasse von Peptidverbindungen zur Behandlung von Allodynie oder andere Arten von chronischen oder Phantomschmerzen
US7622446B2 (en) * 2001-04-18 2009-11-24 The Open University Polypeptides, derivatives and uses thereof
US7491702B2 (en) * 2001-04-18 2009-02-17 The Open University Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same
NZ550482A (en) 2004-04-16 2010-08-27 Sanol Arznei Schwarz Gmbh Use of peptidic compounds for the prophylaxis and treatment of chronic headache
CA2573125A1 (en) * 2004-08-27 2006-03-02 Schwarz Pharma Ag Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain
EP1754476A1 (de) * 2005-08-18 2007-02-21 Schwarz Pharma Ag Lacosamid (SPM 927) zur Behandlung von Myalgien, z.B. Fibromyalgie
US20070048372A1 (en) * 2005-08-18 2007-03-01 Srz Properties, Inc. Method for treating non-inflammatory osteoarthritic pain
US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
GB2432586B (en) * 2005-11-25 2010-01-13 Univ Open Treatment of neurodegenerative disorders
ES2450070T5 (es) 2006-06-15 2018-05-08 Ucb Pharma Gmbh Composición farmacéutica que comprende lacosamida y levetiracetam con efecto anticonvulsionante sinérgico
AU2008297411A1 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
RU2010114040A (ru) * 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение дезлорелина и мастопана в качестве терапевтического средства
SG11201907845SA (en) * 2017-06-14 2019-09-27 Biosolution Co Ltd Anti-wrinkle or anti-inflammatory cosmetic composition including substance p
EP4092038A1 (de) 2017-09-11 2022-11-23 Protagonist Therapeutics, Inc. Opioidagonistpeptide und verwendungen davon
CA3188556A1 (en) * 2020-07-01 2022-01-06 PreveCeutical Medical Inc. Peptides and uses thereof
RU2760133C1 (ru) * 2021-04-22 2021-11-22 Федеральное государственное бюджетное учреждение науки "Научный центр биомедицинских технологий Федерального медико-биологического агентства". Амиды гептапептида для лечения HMGB1-зависимых заболеваний

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254106A (en) * 1976-01-26 1981-03-03 Burroughs Wellcome Co. Biologically active amides
ES455365A1 (es) * 1976-01-26 1978-05-16 Wellcome Found Un metodo de preparacion de un peptido dotado de actividad biologica analoga a la de la morfina.
US4123523A (en) * 1976-06-21 1978-10-31 Imperial Chemical Industries Limited Analgesic and sedative polypeptides
US4371463A (en) * 1977-02-17 1983-02-01 The United States Of America As Represented By The Department Of Health And Human Services Enzyme-resistant opiate pentapeptides
US4081434A (en) * 1977-03-11 1978-03-28 Hoffmann-La Roche Inc. Novel analogs of β-endorphin
US4127533A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octapeptides, intermediates therefor, and compositions and methods employing said octapeptides
US4139504A (en) * 1977-06-16 1979-02-13 Coy David Howard Novel nonapeptides, intermediates therefor, and compositions and methods employing said nonapeptides
GB1604850A (en) * 1977-11-24 1981-12-16 Wellcome Found Biologically active peptides
US4148786A (en) * 1978-06-26 1979-04-10 American Home Products Corporation Analgesic polypeptide
US4178284A (en) * 1978-12-11 1979-12-11 American Home Products Corporation Octapeptides
DE2936099A1 (de) * 1979-09-06 1981-04-02 Victor Dipl.- Chem. 8000 München Brantl Pharmakologisch aktive peptide
EP0044451B1 (de) * 1980-07-17 1984-04-18 Sandoz Ag Pentapeptide, Verfahren zu deren Herstellung, deren pharmazeutische Zusammensetzungen und deren Anwendung
JPS57134451A (en) * 1981-02-13 1982-08-19 Suntory Ltd Peptide opioide
EP0076676B1 (de) * 1981-10-05 1986-12-30 Tni Pharmaceuticals, Inc. Verfahren zur Verwendung von Endorphinen als Antitumormittel
US4462941A (en) * 1982-06-10 1984-07-31 The Regents Of The University Of California Dynorphin amide analogs
JPS59141547A (ja) * 1983-02-01 1984-08-14 Eisai Co Ltd 鎮痛作用を有する新規ペプタイドおよび製法
US4518711A (en) * 1983-05-16 1985-05-21 Gibson-Stephens Institute Conformationally constrained cyclic enkephalin analogs with delta receptor specificity

Also Published As

Publication number Publication date
ZA858456B (en) 1987-07-29
HU203563B (en) 1991-08-28
GR852689B (de) 1986-02-21
DE3588095D1 (de) 1996-04-25
FI854227L (fi) 1986-05-10
ATE135712T1 (de) 1996-04-15
DK513385A (da) 1986-05-10
EP0181001A2 (de) 1986-05-14
FI92935C (fi) 1995-01-25
PH23847A (en) 1989-11-23
SU1433415A3 (ru) 1988-10-23
EP0181001A3 (en) 1989-04-19
CN85109722A (zh) 1986-10-08
ES548667A0 (es) 1987-10-16
CA1267997A (en) 1990-04-17
IL76924A0 (en) 1986-04-29
NO169347C (no) 1992-06-10
EP0181001B1 (de) 1996-03-20
EP0614913A3 (de) 1997-06-04
PT81441B (pt) 1987-11-11
HUT40145A (en) 1986-11-28
ES8800272A1 (es) 1987-10-16
KR880000765B1 (en) 1988-05-06
NO854435L (no) 1986-05-12
US4707468A (en) 1987-11-17
JPH0680079B2 (ja) 1994-10-12
EP0614913A2 (de) 1994-09-14
FI92935B (fi) 1994-10-14
CN1029684C (zh) 1995-09-06
IL76924A (en) 1990-07-12
NZ214122A (en) 1988-08-30
KR860004081A (ko) 1986-06-16
AU588837B2 (en) 1989-09-28
FI854227A0 (fi) 1985-10-28
DK513385D0 (da) 1985-11-07
PT81441A (en) 1985-12-01
NO169347B (no) 1992-03-02
JPS61115097A (ja) 1986-06-02
DK171300B1 (da) 1996-08-26
AU4938985A (en) 1986-05-15

Similar Documents

Publication Publication Date Title
DE3588095D1 (de) Polypeptid, dessen Verfahren zur Herstellung und dieses enthaltende pharmazeutische Zusammensetzung und deren Benutzung
ATE71375T1 (de) Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeure ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
FI906438A0 (fi) Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
ATE21699T1 (de) Verfahren zur herstellung von 2-penemverbindungen.
GR900100406A (en) Preparation process for a pharmaceutical treatment composition
ZA806399B (en) New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use
HU904201D0 (en) Process for producing peptides with haemoregulating effect and pharmaceutical preparatives containing these compounds
GR76886B (de)
AU562271B2 (en) Pharmaceutical composition of corazepam and diphenhydramine
ATE10934T1 (de) Peptid, verfahren zu dessen herstellung und dessen verwendung.
DE3578065D1 (de) 3-mercapto-2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zur herstellung und pharmazeutische zusammensetzungen die sie enthalten.
ATE144257T1 (de) Tetrahydro-4-phenylimino-3-thiophenessigsäuren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee