DK1243262T3 - Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter - Google Patents
Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerterInfo
- Publication number
- DK1243262T3 DK1243262T3 DK01106891T DK01106891T DK1243262T3 DK 1243262 T3 DK1243262 T3 DK 1243262T3 DK 01106891 T DK01106891 T DK 01106891T DK 01106891 T DK01106891 T DK 01106891T DK 1243262 T3 DK1243262 T3 DK 1243262T3
- Authority
- DK
- Denmark
- Prior art keywords
- pain
- compounds
- inflammatory pain
- inflammatory
- hitherto unknown
- Prior art date
Links
- 206010065390 Inflammatory pain Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000002981 neuropathic effect Effects 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 208000002193 Pain Diseases 0.000 abstract 5
- 229940035676 analgesics Drugs 0.000 abstract 2
- 239000000730 antalgic agent Substances 0.000 abstract 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 2
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 230000003502 anti-nociceptive effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 229940005483 opioid analgesics Drugs 0.000 abstract 1
- 230000003349 osteoarthritic effect Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01106891A EP1243262B1 (en) | 2001-03-20 | 2001-03-20 | Novel use of a peptide class of compound for treating non-neuropathic inflammatory pain |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1243262T3 true DK1243262T3 (da) | 2006-10-02 |
Family
ID=8176844
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01106891T DK1243262T3 (da) | 2001-03-20 | 2001-03-20 | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter |
DK02727437T DK1373300T3 (da) | 2001-03-20 | 2002-03-19 | Ny anvendelse af en peptidklasse af forbindelser til at behandle ikke-neuropatiske inflammatoriske smerter |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02727437T DK1373300T3 (da) | 2001-03-20 | 2002-03-19 | Ny anvendelse af en peptidklasse af forbindelser til at behandle ikke-neuropatiske inflammatoriske smerter |
Country Status (31)
Country | Link |
---|---|
US (3) | US6803481B2 (da) |
EP (2) | EP1243262B1 (da) |
JP (1) | JP4955906B2 (da) |
KR (1) | KR100773100B1 (da) |
CN (2) | CN101332292B (da) |
AT (2) | ATE327744T1 (da) |
AU (1) | AU2002257681C1 (da) |
BR (1) | BR0205823A (da) |
CA (1) | CA2419397C (da) |
CY (3) | CY1105533T1 (da) |
CZ (1) | CZ20032763A3 (da) |
DE (3) | DE60120104T2 (da) |
DK (2) | DK1243262T3 (da) |
EA (1) | EA007532B1 (da) |
ES (2) | ES2262567T3 (da) |
FR (1) | FR09C0041I2 (da) |
HK (1) | HK1058368A1 (da) |
HU (1) | HUP0303600A3 (da) |
IL (2) | IL154087A0 (da) |
LU (1) | LU91590I2 (da) |
MX (1) | MXPA03008467A (da) |
NL (1) | NL300399I1 (da) |
NO (1) | NO20033629L (da) |
NZ (1) | NZ523865A (da) |
PL (1) | PL216213B1 (da) |
PT (2) | PT1243262E (da) |
SI (2) | SI1373300T1 (da) |
SK (1) | SK287539B6 (da) |
UA (1) | UA82645C2 (da) |
WO (1) | WO2002074784A2 (da) |
ZA (1) | ZA200300858B (da) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1486205T3 (da) * | 2000-08-25 | 2008-02-18 | Res Corp Technologies Inc | Anvendelse af antikonvulsive aminosyrer til behandling af migræne |
DK1243262T3 (da) * | 2001-03-20 | 2006-10-02 | Sanol Arznei Schwarz Gmbh | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter |
ATE228358T1 (de) * | 2001-03-21 | 2002-12-15 | Sanol Arznei Schwarz Gmbh | Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen |
KR20060111524A (ko) * | 2003-12-02 | 2006-10-27 | 쉬바르츠파르마에이지 | 펩타이드 화합물들의 중추 신경병증성 통증 치료를 위한신규한 용도 |
US20100256179A1 (en) * | 2004-03-26 | 2010-10-07 | Ucb Pharma Gmbh | Combination therapy for pain in painful diabetic neuropathy |
EP1579858A1 (en) * | 2004-03-26 | 2005-09-28 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in painful diabetic neuropathy |
US20070042969A1 (en) * | 2004-03-26 | 2007-02-22 | Srz Properties, Inc. | Combination therapy for pain in painful diabetic neuropathy |
CA2562937A1 (en) * | 2004-04-16 | 2005-10-27 | Schwarz Pharma Ag | Use of peptidic compounds for the prophylaxis and treatment of chronic headache |
EP1604654A1 (en) | 2004-05-18 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating dyskinesia |
CN100562312C (zh) * | 2004-05-18 | 2009-11-25 | 舒沃茨药物股份公司 | 肽化合物用于治疗运动障碍的新用途 |
EP1604655A1 (en) * | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
EP1604656A1 (en) * | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS) |
US7427601B2 (en) * | 2004-06-24 | 2008-09-23 | Schwarz Pharma Ag | Method for treating tremor |
WO2006021412A2 (en) * | 2004-08-27 | 2006-03-02 | Schwarz Pharma Ag | Use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain |
EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
CA2595330A1 (en) | 2005-01-28 | 2006-08-03 | Schwarz Pharma Ag | Spm 927 for add-on therapy of schizophrenia |
US20060252749A1 (en) * | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
US20070048372A1 (en) * | 2005-08-18 | 2007-03-01 | Srz Properties, Inc. | Method for treating non-inflammatory osteoarthritic pain |
GB0523550D0 (en) | 2005-11-18 | 2005-12-28 | Hunter Fleming Ltd | Therapeutic uses of steroidal compounds |
JP2009539792A (ja) * | 2006-06-08 | 2009-11-19 | シュヴァルツ・ファーマ・アーゲー | 疼痛の医学的状態のための治療組合せ |
EP1920780A1 (en) * | 2006-10-12 | 2008-05-14 | Schwarz Pharma Ag | Peptide compounds for the treatment of hyperexcitability disorders |
CN101466390B (zh) | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
EP1873527A1 (en) * | 2006-06-30 | 2008-01-02 | Schwarz Pharma Ag | Method for identifying CRMP modulators |
EP2037965B1 (en) * | 2006-06-15 | 2017-08-30 | UCB Pharma GmbH | Pharmaceutical composition with synergistic anticonvulsant effect |
EP2509939A4 (en) | 2009-09-23 | 2013-09-18 | Univ North Carolina | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2- (ACYLAMIDO) ACETIC ACID AND 2- (ACYLAMIDO) PROPIONIC ACIDS: POWERFUL NEUROLOGIC AGENTS |
EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
EP2645997B1 (en) | 2010-12-02 | 2022-08-10 | UCB Pharma GmbH | Once daily formulation of lacosamide |
GB2524689B (en) | 2011-05-20 | 2016-01-27 | Gw Pharma Ltd | Cannabinoids for use in the treatment of neuropathic pain |
Family Cites Families (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2937698A1 (de) | 1979-09-18 | 1981-04-02 | A. Nattermann & Cie GmbH, 5000 Köln | N-propionylsarcosinanilide, deren herstellungsverfahren und arzneimittel auf deren basis |
FR2480747A1 (fr) | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
US4533657A (en) | 1981-07-24 | 1985-08-06 | Sterling Drug Inc. | Analgesic dipeptide amides and method of use and composition thereof |
FR2518088B1 (fr) | 1981-12-16 | 1987-11-27 | Roques Bernard | Nouveaux derives d'aminoacides, et leur application therapeutique |
US4510082A (en) | 1983-03-07 | 1985-04-09 | Eli Lilly And Company | Pharmacologically active peptides |
JPH0680079B2 (ja) | 1984-11-09 | 1994-10-12 | エーザイ株式会社 | ポリペプチド |
US5654301A (en) * | 1985-02-15 | 1997-08-05 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
US5378729A (en) * | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
GB9103454D0 (en) | 1991-02-19 | 1991-04-03 | Pfizer Ltd | Therapeutic agents |
US5656267A (en) * | 1991-08-22 | 1997-08-12 | Sagen; Jacqueline | Implantable cells that alleviate chronic pain in humans |
TW217417B (da) | 1991-12-04 | 1993-12-11 | Manyu Seiyaku Kk | |
US5278729A (en) * | 1992-04-10 | 1994-01-11 | Magnavox Electronic Systems Company | Compact rotatable electrical device |
US5585358A (en) | 1993-07-06 | 1996-12-17 | Yissum Research Development Corporation Of The Hebrew University Of Jerusalem | Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents |
AU678884B2 (en) * | 1994-01-22 | 1997-06-12 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
IL112759A0 (en) * | 1994-02-25 | 1995-05-26 | Khepri Pharmaceuticals Inc | Novel cysteine protease inhibitors |
GB9504854D0 (en) | 1994-03-31 | 1995-04-26 | Zeneca Ltd | Nitrogen derivatives |
US5536853A (en) | 1994-04-11 | 1996-07-16 | Chiron Corporation | Opiate receptor ligands |
MY113062A (en) * | 1994-05-10 | 2001-11-30 | The Wellcome Foundation Ltd | Amide derivatives and their therapeutic use |
US5508266A (en) | 1994-06-22 | 1996-04-16 | Ciba-Geigy Corporation | Gem-disubstituted amino acid derivatives |
ES2133807T3 (es) | 1994-10-05 | 1999-09-16 | Darwin Discovery Ltd | Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas. |
DE19533023B4 (de) | 1994-10-14 | 2007-05-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
US5780589A (en) | 1994-11-30 | 1998-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | Ultraselective opioidmimetic peptides and pharmacological and therapeutic uses thereof |
US5760038A (en) | 1995-02-06 | 1998-06-02 | Bristol-Myers Squibb Company | Substituted biphenyl sulfonamide endothelin antagonists |
US5849737A (en) | 1995-04-14 | 1998-12-15 | The Regents Of The University Of California | Compositions and methods for treating pain |
WO1997003677A1 (en) | 1995-07-24 | 1997-02-06 | Trustees Of Boston University | Inhibition of nmda receptor activity by pregnenolone sulfate derivatives |
US6114390A (en) | 1995-11-30 | 2000-09-05 | Karl Thomae Gmbh | Amino acid derivatives, pharmaceutical compositions containing these compounds and processes for preparing them |
US6037324A (en) | 1996-01-04 | 2000-03-14 | Leukosite, Inc. | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor |
GB9601724D0 (en) | 1996-01-29 | 1996-03-27 | Merck Sharp & Dohme | Therapeutic agents |
US5773475A (en) * | 1997-03-17 | 1998-06-30 | Research Corporation Technologies, Inc. | Anticonvulsant enantiomeric amino acid derivatives |
DE19614534A1 (de) | 1996-04-12 | 1997-10-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
DE19614533A1 (de) | 1996-04-12 | 1997-10-16 | Basf Ag | Neue alpha-Hydroxysäurederivate, ihre Herstellung und Verwendung |
DE19614542A1 (de) | 1996-04-12 | 1997-10-16 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung |
US6277825B1 (en) * | 1996-07-22 | 2001-08-21 | University Of Utah Research Foundation | Use of conantokins for treating pain |
BR9710536A (pt) | 1996-07-24 | 1999-08-17 | Warner Lambert Co | Isobutilgaba e seus derivados para o tratamento da dor |
US6589994B1 (en) | 1996-08-30 | 2003-07-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound |
US6126939A (en) | 1996-09-03 | 2000-10-03 | Yeda Research And Development Co. Ltd. | Anti-inflammatory dipeptide and pharmaceutical composition thereof |
DE19636046A1 (de) | 1996-09-05 | 1998-03-12 | Basf Ag | Neue Carbonsäurederivate, ihre Herstellung und Verwendung als gemischte ET¶A¶/ET¶B¶-Rezeptorantagonisten |
US6034136A (en) * | 1997-03-20 | 2000-03-07 | Novartis Ag | Certain cyclic thio substituted acylaminoacid amide derivatives |
US5866585A (en) | 1997-05-22 | 1999-02-02 | Synchroneuron, Llc | Methods of treating tardive dyskinesia using NMDA receptor antagonists |
ATE320249T1 (de) | 1997-07-08 | 2006-04-15 | Ono Pharmaceutical Co | Aminosäurederivate |
US6737408B1 (en) | 1997-08-07 | 2004-05-18 | University Of Cincinnati | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm |
AU7696098A (en) * | 1997-08-11 | 1999-03-01 | Algos Pharmaceutical Corporation | Substance p inhibitors in combination with nmda-blockers for treating pain |
DE19743143A1 (de) | 1997-09-30 | 1999-04-01 | Knoll Ag | Pharmazeutische Kombinationspräparate |
NZ504316A (en) | 1997-10-31 | 2002-12-20 | Basf Ag | Pyrimidine substituted carboxylic acid derivatives which have amido side-chains useful as endothelin receptor antagonists |
US6028102A (en) * | 1998-02-24 | 2000-02-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Anticonvulsant drugs and pharmaceutical compositions thereof |
CN100424079C (zh) | 1999-09-03 | 2008-10-08 | 埃科特莱茵药品有限公司 | 双磺胺 |
SE0001373D0 (sv) * | 2000-04-13 | 2000-04-13 | Karolinska Innovations Ab | NPY Y1 receptor agonists and antagonists |
AU8830801A (en) | 2000-08-17 | 2002-02-25 | Teva Pharma | Use of derivatives of valproic acid amides and 2-valproenic acid amides for the treatment or prevention of pain and/or headache disorders |
DK1486205T3 (da) | 2000-08-25 | 2008-02-18 | Res Corp Technologies Inc | Anvendelse af antikonvulsive aminosyrer til behandling af migræne |
ATE397584T1 (de) | 2000-11-21 | 2008-06-15 | Ucb Pharma Sa | N-alkylierte gaba verbindungen, verfahren zu deren herstellung und deren verwendung als arzneimittel |
DK1243262T3 (da) * | 2001-03-20 | 2006-10-02 | Sanol Arznei Schwarz Gmbh | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter |
ATE228358T1 (de) | 2001-03-21 | 2002-12-15 | Sanol Arznei Schwarz Gmbh | Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen |
BR0207715A (pt) | 2001-03-27 | 2004-03-23 | Actelion Pharmaceuticals Ltd | Compostos, composições farmacêuticas, e uso de um ou mais compostos |
BR0209199A (pt) | 2001-04-26 | 2006-02-07 | Bristol Myers Squibb Co | Controle de campactabilidade através de cristalização |
ITMI20011308A1 (it) | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per il dolore cronico |
AU2003243180A1 (en) | 2002-05-17 | 2003-12-12 | Xenoport, Inc. | Amino acid conjugates providing for sustained systemic concentrations of gaba analogues |
ATE361289T1 (de) | 2002-08-05 | 2007-05-15 | Lilly Co Eli | Piperazinsubstituierte arylbenzodiazepine |
AU2003276201A1 (en) | 2002-11-11 | 2004-06-03 | Bayer Healthcare Ag | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist |
CA2544467C (en) | 2002-11-18 | 2014-02-18 | John M. Stewart | Paralytic peptide for use in neuromuscular therapy |
US7687080B2 (en) | 2002-11-25 | 2010-03-30 | Taraxos Inc. | Treatment of neuropathy |
BR0317392A (pt) | 2002-12-19 | 2005-12-20 | Pharmacia Corp | Formulação não-higroscópica incluindo uma droga higroscópica |
AU2004207009A1 (en) | 2003-01-30 | 2004-08-12 | Dynogen Pharmaceuticals, Inc. | Use of sodium channel modulators for treating gastrointestinal tract disorders |
US20040209960A1 (en) | 2003-01-30 | 2004-10-21 | Dynogen Pharmaceuticals, Inc. | Methods of treating lower urinary tract disorders using sodium channell modulators |
US20040265375A1 (en) | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
US20040266743A1 (en) | 2003-05-09 | 2004-12-30 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and a renin inhibitor |
US7320675B2 (en) | 2003-08-21 | 2008-01-22 | Cardiac Pacemakers, Inc. | Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure |
EP1537862A1 (en) | 2003-12-02 | 2005-06-08 | Schwarz Pharma Ag | Novel use of peptide compounds for treating central neuropathic pain |
KR20060111524A (ko) | 2003-12-02 | 2006-10-27 | 쉬바르츠파르마에이지 | 펩타이드 화합물들의 중추 신경병증성 통증 치료를 위한신규한 용도 |
EP1541138A1 (en) | 2003-12-05 | 2005-06-15 | Schwarz Pharma Ag | Novel use of peptide compounds for treating status epilepticus or related conditions |
US20060009384A1 (en) | 2003-12-05 | 2006-01-12 | David Rudd | Novel use of peptide compounds for treating status epilepticus or related conditions |
EP1579858A1 (en) | 2004-03-26 | 2005-09-28 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in painful diabetic neuropathy |
US20070042969A1 (en) | 2004-03-26 | 2007-02-22 | Srz Properties, Inc. | Combination therapy for pain in painful diabetic neuropathy |
US20050227961A1 (en) | 2004-04-08 | 2005-10-13 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome |
CA2562937A1 (en) | 2004-04-16 | 2005-10-27 | Schwarz Pharma Ag | Use of peptidic compounds for the prophylaxis and treatment of chronic headache |
EP1604654A1 (en) | 2004-05-18 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating dyskinesia |
EP1604656A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS) |
EP1604655A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
US7427601B2 (en) | 2004-06-24 | 2008-09-23 | Schwarz Pharma Ag | Method for treating tremor |
WO2006021412A2 (en) | 2004-08-27 | 2006-03-02 | Schwarz Pharma Ag | Use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain |
EP1642889A1 (en) | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
EP1688137A1 (en) | 2005-01-28 | 2006-08-09 | Schwarz Pharma Ag | SPM 927 for add-on therapy of schizophrenia |
US20060252749A1 (en) | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
EP1754476A1 (en) | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
US20070043120A1 (en) | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
US20070048372A1 (en) | 2005-08-18 | 2007-03-01 | Srz Properties, Inc. | Method for treating non-inflammatory osteoarthritic pain |
-
2001
- 2001-03-20 DK DK01106891T patent/DK1243262T3/da active
- 2001-03-20 DE DE60120104T patent/DE60120104T2/de not_active Expired - Fee Related
- 2001-03-20 EP EP01106891A patent/EP1243262B1/en not_active Expired - Lifetime
- 2001-03-20 AT AT01106891T patent/ATE327744T1/de not_active IP Right Cessation
- 2001-03-20 ES ES01106891T patent/ES2262567T3/es not_active Expired - Lifetime
- 2001-03-20 PT PT01106891T patent/PT1243262E/pt unknown
-
2002
- 2002-03-19 AU AU2002257681A patent/AU2002257681C1/en not_active Ceased
- 2002-03-19 JP JP2002573793A patent/JP4955906B2/ja not_active Expired - Fee Related
- 2002-03-19 AT AT02727437T patent/ATE431833T1/de active
- 2002-03-19 US US10/344,885 patent/US6803481B2/en not_active Expired - Fee Related
- 2002-03-19 CN CN2008101283801A patent/CN101332292B/zh not_active Expired - Fee Related
- 2002-03-19 EP EP02727437A patent/EP1373300B1/en not_active Expired - Lifetime
- 2002-03-19 PL PL362985A patent/PL216213B1/pl not_active IP Right Cessation
- 2002-03-19 CZ CZ20032763A patent/CZ20032763A3/cs unknown
- 2002-03-19 DK DK02727437T patent/DK1373300T3/da active
- 2002-03-19 HU HU0303600A patent/HUP0303600A3/hu unknown
- 2002-03-19 BR BR0205823-5A patent/BR0205823A/pt not_active Application Discontinuation
- 2002-03-19 DE DE122009000053C patent/DE122009000053I1/de active Pending
- 2002-03-19 ES ES02727437T patent/ES2326627T3/es not_active Expired - Lifetime
- 2002-03-19 CA CA002419397A patent/CA2419397C/en not_active Expired - Fee Related
- 2002-03-19 MX MXPA03008467A patent/MXPA03008467A/es active IP Right Grant
- 2002-03-19 WO PCT/EP2002/003034 patent/WO2002074784A2/en active IP Right Grant
- 2002-03-19 DE DE60232407T patent/DE60232407D1/de not_active Expired - Lifetime
- 2002-03-19 PT PT02727437T patent/PT1373300E/pt unknown
- 2002-03-19 SI SI200230842T patent/SI1373300T1/sl unknown
- 2002-03-19 NZ NZ523865A patent/NZ523865A/xx unknown
- 2002-03-19 SK SK1283-2003A patent/SK287539B6/sk not_active IP Right Cessation
- 2002-03-19 UA UA2003109401A patent/UA82645C2/uk unknown
- 2002-03-19 IL IL15408702A patent/IL154087A0/xx unknown
- 2002-03-19 EA EA200300932A patent/EA007532B1/ru not_active IP Right Cessation
- 2002-03-19 CN CNB028067614A patent/CN100415225C/zh not_active Expired - Fee Related
- 2002-03-19 KR KR1020037002844A patent/KR100773100B1/ko not_active IP Right Cessation
- 2002-03-19 SI SI200220008A patent/SI21170A/sl not_active IP Right Cessation
-
2003
- 2003-01-22 IL IL154087A patent/IL154087A/en not_active IP Right Cessation
- 2003-01-31 ZA ZA200300858A patent/ZA200300858B/xx unknown
- 2003-08-15 NO NO20033629A patent/NO20033629L/no not_active Application Discontinuation
-
2004
- 2004-02-16 HK HK04101107.4A patent/HK1058368A1/xx not_active IP Right Cessation
- 2004-10-08 US US10/962,240 patent/US20050085423A1/en not_active Abandoned
-
2006
- 2006-08-21 US US11/507,110 patent/US8053476B2/en not_active Expired - Fee Related
- 2006-08-30 CY CY20061101223T patent/CY1105533T1/el unknown
-
2009
- 2009-08-05 LU LU91590C patent/LU91590I2/fr unknown
- 2009-08-06 NL NL300399C patent/NL300399I1/nl unknown
- 2009-08-12 CY CY20091100865T patent/CY1109308T1/el unknown
- 2009-09-07 FR FR09C0041C patent/FR09C0041I2/fr active Active
- 2009-09-16 CY CY2009013C patent/CY2009013I1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1243262T3 (da) | Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter | |
IS6785A (is) | EP4 viðtakahindrar til meðhöndlunar á liðagigt | |
EA200300933A1 (ru) | Новое применение соединения из класса пептидов для лечения аллодинии или других различных типов хронической или фантомной боли | |
IL172773A0 (en) | Formulations for the treatment of arhritis conditions | |
BRPI0416268A (pt) | composições de delta-9-thc e métodos para o tratamento de sintomas associados à esclerose múltipla | |
EA200400410A1 (ru) | Комбинация нспвлс и ингибитора pde-4 | |
CY1112555T1 (el) | Διεργασια χημικης συζευξης με ενα παραγωγο φαινυλ βορονικου οξεος | |
CL2007002387A1 (es) | Uso de compuestos derivados de 2,5-dihidroxibenceno para el tratamiento de artritis y dolor. | |
BR0213181A (pt) | Combinações de inibidor de cox-2 | |
ATE405834T1 (de) | Bindungsoberfläche | |
SE0302361D0 (sv) | Inhibering av upptagning av monoamin | |
BR9913526A (pt) | Métodos de tratamento da osteoartrite com inibidores de sintase de óxido nìtrico induzìvel | |
ATE508121T1 (de) | Derivate von hydroxamsäure als metalloproteinaseinhibitoren | |
FI20002525A (fi) | Tulehduksenvastaisia aineita | |
BRPI0409586A (pt) | ácidos hidroxámicos úteis no tratamento de distúrbios hiperproliferativos | |
PT1345612E (pt) | Utilizacao de heparina de massa molecular reduzida para o tratamento de osteoartrose | |
DK1366033T3 (da) | Kemiske forbindelser | |
BR0209861A (pt) | Processo para a produção de quinazolinas | |
BR0304636A (pt) | Uso de composições para o tratamento de rosácea |