JPH06510033A - ベータ−フェニルイソセリン誘導体の製造法及びその利用 - Google Patents

ベータ−フェニルイソセリン誘導体の製造法及びその利用

Info

Publication number
JPH06510033A
JPH06510033A JP5504146A JP50414693A JPH06510033A JP H06510033 A JPH06510033 A JP H06510033A JP 5504146 A JP5504146 A JP 5504146A JP 50414693 A JP50414693 A JP 50414693A JP H06510033 A JPH06510033 A JP H06510033A
Authority
JP
Japan
Prior art keywords
group
mmol
mixture
carried out
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5504146A
Other languages
English (en)
Japanese (ja)
Inventor
デニ，ジヤン−ノエル
グリーン，アンドリユウ
カナザワ，アリス
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH06510033A publication Critical patent/JPH06510033A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
JP5504146A 1991-08-19 1992-08-17 ベータ−フェニルイソセリン誘導体の製造法及びその利用 Pending JPH06510033A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR919110398A FR2680506B1 (fr) 1991-08-19 1991-08-19 Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
FR91/10398 1991-08-19
PCT/FR1992/000795 WO1993004038A1 (fr) 1991-08-19 1992-08-17 PROCEDE DE PREPARATION DE DERIVES DE LA β-PHENYLISOSERINE ET LEUR UTILISATION

Publications (1)

Publication Number Publication Date
JPH06510033A true JPH06510033A (ja) 1994-11-10

Family

ID=9416254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5504146A Pending JPH06510033A (ja) 1991-08-19 1992-08-17 ベータ−フェニルイソセリン誘導体の製造法及びその利用

Country Status (16)

Country Link
EP (2) EP0528729A1 (enExample)
JP (1) JPH06510033A (enExample)
AU (1) AU2490492A (enExample)
CA (1) CA2113827A1 (enExample)
CZ (1) CZ35494A3 (enExample)
FI (1) FI940775A7 (enExample)
FR (1) FR2680506B1 (enExample)
HU (1) HUT68255A (enExample)
MX (1) MX9204635A (enExample)
NO (1) NO940027L (enExample)
NZ (1) NZ243972A (enExample)
SK (1) SK19094A3 (enExample)
TW (1) TW222620B (enExample)
WO (1) WO1993004038A1 (enExample)
YU (1) YU78092A (enExample)
ZA (1) ZA926189B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005532996A (ja) * 2002-02-27 2005-11-04 フェリング ベスローテン フェンノートシャップ ヘプタペプチドオキシトシンアナログを製造するための中間体及び方法

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
CA2155304C (en) * 1993-02-05 2010-07-20 Charles Swindell Syntheses of paclitaxel, analogs and intermediates with variable a-ring side chains
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US5675025A (en) * 1995-06-07 1997-10-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
US6107497A (en) * 1996-02-29 2000-08-22 Napro Biotherapeutics, Inc. Intermediate for use in docetaxel synthesis and production method therefor
US5688977A (en) * 1996-02-29 1997-11-18 Napro Biotherapeutics, Inc. Method for docetaxel synthesis
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
US6452025B1 (en) 2001-04-25 2002-09-17 Napro Biotherapeutics, Inc. Three-step conversion of protected taxane ester to paclitaxel
BR112014031421A2 (pt) 2012-06-15 2017-06-27 Brigham & Womens Hospital Inc composições para tratamento de câncer e métodos para produção das mesmas
KR20160132496A (ko) 2014-04-03 2016-11-18 인빅터스 온콜로지 피비티. 엘티디. 초분자 조합 치료제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005532996A (ja) * 2002-02-27 2005-11-04 フェリング ベスローテン フェンノートシャップ ヘプタペプチドオキシトシンアナログを製造するための中間体及び方法

Also Published As

Publication number Publication date
EP0599973A1 (fr) 1994-06-08
MX9204635A (es) 1993-02-01
AU2490492A (en) 1993-03-16
FR2680506A1 (fr) 1993-02-26
CA2113827A1 (fr) 1993-03-04
WO1993004038A1 (fr) 1993-03-04
FI940775A0 (fi) 1994-02-18
FR2680506B1 (fr) 1994-09-02
CZ35494A3 (en) 1994-07-13
EP0528729A1 (fr) 1993-02-24
ZA926189B (en) 1993-03-01
FI940775L (fi) 1994-02-18
TW222620B (enExample) 1994-04-21
NO940027D0 (no) 1994-01-04
YU78092A (sh) 1995-10-03
SK19094A3 (en) 1994-09-07
HUT68255A (en) 1995-06-28
FI940775A7 (fi) 1994-02-18
HU9400478D0 (en) 1994-06-28
NZ243972A (en) 1994-11-25
NO940027L (no) 1994-01-04

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