CA2113827A1 - Procede de preparation de derives de la .beta.-phenylisoserine et leur utilisation - Google Patents

Procede de preparation de derives de la .beta.-phenylisoserine et leur utilisation

Info

Publication number
CA2113827A1
CA2113827A1 CA002113827A CA2113827A CA2113827A1 CA 2113827 A1 CA2113827 A1 CA 2113827A1 CA 002113827 A CA002113827 A CA 002113827A CA 2113827 A CA2113827 A CA 2113827A CA 2113827 A1 CA2113827 A1 CA 2113827A1
Authority
CA
Canada
Prior art keywords
mmol
general formula
beta
phenyl
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002113827A
Other languages
English (en)
French (fr)
Inventor
Jean-Noel Denis
Andrew Greene
Alice Kanazawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2113827A1 publication Critical patent/CA2113827A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
CA002113827A 1991-08-19 1992-08-17 Procede de preparation de derives de la .beta.-phenylisoserine et leur utilisation Abandoned CA2113827A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR919110398A FR2680506B1 (fr) 1991-08-19 1991-08-19 Procede de preparation de derives de la beta-phenylisoserine et leur utilisation.
FR9110398 1991-08-19

Publications (1)

Publication Number Publication Date
CA2113827A1 true CA2113827A1 (fr) 1993-03-04

Family

ID=9416254

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002113827A Abandoned CA2113827A1 (fr) 1991-08-19 1992-08-17 Procede de preparation de derives de la .beta.-phenylisoserine et leur utilisation

Country Status (16)

Country Link
EP (2) EP0528729A1 (enExample)
JP (1) JPH06510033A (enExample)
AU (1) AU2490492A (enExample)
CA (1) CA2113827A1 (enExample)
CZ (1) CZ35494A3 (enExample)
FI (1) FI940775A7 (enExample)
FR (1) FR2680506B1 (enExample)
HU (1) HUT68255A (enExample)
MX (1) MX9204635A (enExample)
NO (1) NO940027L (enExample)
NZ (1) NZ243972A (enExample)
SK (1) SK19094A3 (enExample)
TW (1) TW222620B (enExample)
WO (1) WO1993004038A1 (enExample)
YU (1) YU78092A (enExample)
ZA (1) ZA926189B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
CA2155304C (en) * 1993-02-05 2010-07-20 Charles Swindell Syntheses of paclitaxel, analogs and intermediates with variable a-ring side chains
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US5675025A (en) * 1995-06-07 1997-10-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
US6107497A (en) * 1996-02-29 2000-08-22 Napro Biotherapeutics, Inc. Intermediate for use in docetaxel synthesis and production method therefor
US5688977A (en) * 1996-02-29 1997-11-18 Napro Biotherapeutics, Inc. Method for docetaxel synthesis
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
US6452025B1 (en) 2001-04-25 2002-09-17 Napro Biotherapeutics, Inc. Three-step conversion of protected taxane ester to paclitaxel
ATE346084T1 (de) * 2002-02-27 2006-12-15 Ferring Bv Zwischenprodukte und verfahren zur herstellung von heptapeptid-oxytocinanaloga
BR112014031421A2 (pt) 2012-06-15 2017-06-27 Brigham & Womens Hospital Inc composições para tratamento de câncer e métodos para produção das mesmas
KR20160132496A (ko) 2014-04-03 2016-11-18 인빅터스 온콜로지 피비티. 엘티디. 초분자 조합 치료제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.

Also Published As

Publication number Publication date
EP0599973A1 (fr) 1994-06-08
MX9204635A (es) 1993-02-01
AU2490492A (en) 1993-03-16
FR2680506A1 (fr) 1993-02-26
WO1993004038A1 (fr) 1993-03-04
FI940775A0 (fi) 1994-02-18
FR2680506B1 (fr) 1994-09-02
CZ35494A3 (en) 1994-07-13
EP0528729A1 (fr) 1993-02-24
ZA926189B (en) 1993-03-01
FI940775L (fi) 1994-02-18
TW222620B (enExample) 1994-04-21
NO940027D0 (no) 1994-01-04
YU78092A (sh) 1995-10-03
SK19094A3 (en) 1994-09-07
HUT68255A (en) 1995-06-28
FI940775A7 (fi) 1994-02-18
HU9400478D0 (en) 1994-06-28
NZ243972A (en) 1994-11-25
NO940027L (no) 1994-01-04
JPH06510033A (ja) 1994-11-10

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Legal Events

Date Code Title Description
FZDE Discontinued