JPH02180868A - ３，５‐ジメチル‐４‐メトキシピリジン誘導体の製造方法ならびにそのための新規な中間生成物 - Google Patents
３，５‐ジメチル‐４‐メトキシピリジン誘導体の製造方法ならびにそのための新規な中間生成物Info
- Publication number
- JPH02180868A JPH02180868A JP1294101A JP29410189A JPH02180868A JP H02180868 A JPH02180868 A JP H02180868A JP 1294101 A JP1294101 A JP 1294101A JP 29410189 A JP29410189 A JP 29410189A JP H02180868 A JPH02180868 A JP H02180868A
- Authority
- JP
- Japan
- Prior art keywords
- dimethyl
- methoxypyridine
- methanol
- carried out
- methamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Manufacture Of Tobacco Products (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT2789/88 | 1988-11-15 | ||
| AT0278988A AT391693B (de) | 1988-11-15 | 1988-11-15 | Verfahren zur herstellung von 3-5-dimethyl-4methoxypyridinderivaten sowie neues zwischenprodukt hierfuer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH02180868A true JPH02180868A (ja) | 1990-07-13 |
Family
ID=3540308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1294101A Pending JPH02180868A (ja) | 1988-11-15 | 1989-11-14 | ３，５‐ジメチル‐４‐メトキシピリジン誘導体の製造方法ならびにそのための新規な中間生成物 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5066810A (en, 2012) |
| EP (1) | EP0369208B1 (en, 2012) |
| JP (1) | JPH02180868A (en, 2012) |
| KR (1) | KR900007803A (en, 2012) |
| CN (1) | CN1042705A (en, 2012) |
| AT (2) | AT391693B (en, 2012) |
| AU (1) | AU628100B2 (en, 2012) |
| CA (1) | CA2002757A1 (en, 2012) |
| CS (1) | CS276357B6 (en, 2012) |
| DD (1) | DD284877A5 (en, 2012) |
| DE (2) | DE3840372A1 (en, 2012) |
| DK (1) | DK568989A (en, 2012) |
| ES (1) | ES2053906T3 (en, 2012) |
| FI (1) | FI895389A7 (en, 2012) |
| GR (1) | GR3007391T3 (en, 2012) |
| HU (1) | HU207995B (en, 2012) |
| IL (1) | IL92152A (en, 2012) |
| NO (1) | NO894410L (en, 2012) |
| NZ (1) | NZ231252A (en, 2012) |
| PH (1) | PH25813A (en, 2012) |
| PT (1) | PT92307B (en, 2012) |
| SU (1) | SU1745121A3 (en, 2012) |
| YU (1) | YU216389A (en, 2012) |
| ZA (1) | ZA898273B (en, 2012) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004506716A (ja) * | 2000-08-25 | 2004-03-04 | バイエル・クロツプサイエンス・エス・アー | ２−アミノエチルピリジンの調製方法 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2024357A6 (es) * | 1990-12-05 | 1992-02-16 | Genesis Para La Investigacion | Procedimiento de obtencion de halohidrato de 2-halometil-3,5-dimetil-4-metoxipiri-dina. |
| ES2035767B1 (es) * | 1991-04-05 | 1994-02-01 | Genesis Para La Investigacion | Procedimiento de obtencion de 2-hidroximetil-3,5-dimetilpiridinas 4-sustituidas. |
| DE4411657A1 (de) * | 1994-04-02 | 1995-10-05 | Basf Ag | Verfahren zur Herstellung von 6-Hydroxymethylchinolinen |
| ES2097089B1 (es) * | 1995-02-01 | 1997-12-16 | Esteve Quimica Sa | Procedimiento para la preparacion de 2-hidroximetil-3,5-dimetil-4-metoxipiridina. |
| US5625069A (en) * | 1996-07-22 | 1997-04-29 | Development Center For Biotechnology | Process for preparing 2-cyano-3,5-dimethyl-4-methoxypyridine |
| US5616713A (en) * | 1996-07-22 | 1997-04-01 | Development Center For Biotechnology | Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine |
| US6437139B1 (en) | 1997-05-06 | 2002-08-20 | Pdi-Research Laboratories, Inc. | Synthesis of pharmaceutically useful pyridine derivatives |
| CA2204580A1 (en) * | 1997-05-06 | 1998-11-06 | Michel Zoghbi | Synthesis of pharmaceutically useful pyridine derivatives |
| CA2415842A1 (en) | 2000-08-25 | 2002-02-28 | Michael Mellor | Process for the preparation of 2-aminoethylpyridines |
| GB0025616D0 (en) * | 2000-10-19 | 2000-12-06 | Aventis Cropscience Sa | Novel process |
| EP1422221A1 (en) * | 2002-11-20 | 2004-05-26 | Bayer CropScience SA | Novel process for the preparation of 2-aminomethylpyridine derivative |
| WO2008092939A2 (en) | 2007-01-31 | 2008-08-07 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically pure omeprazole via salt formation with a chiral amine or treatment with an entiomer converting enzyme and chromatographic separation |
| CN101648907B (zh) * | 2009-09-14 | 2011-08-03 | 南京第一农药集团有限公司 | 2-氯甲基-4-甲氧基-3,5-二甲基吡啶盐酸盐的纯化方法 |
| CN101648912B (zh) * | 2009-09-14 | 2012-07-04 | 南京第一农药集团有限公司 | 一种4-硝基-3,5-二甲基吡啶-n-氧化物的连续化制备方法 |
| CN102603620B (zh) * | 2012-01-13 | 2014-10-29 | 江苏中邦制药有限公司 | 一种氯甲基吡啶或其吡啶衍生物盐酸盐的合成方法 |
| WO2014091450A1 (en) * | 2012-12-12 | 2014-06-19 | Ranbaxy Laboratories Limited | Process for the preparation of rabeprazole |
| CN114805193B (zh) * | 2022-04-19 | 2023-06-20 | 南京红太阳医药研究院有限公司 | 一种奥美拉唑中间体的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3829429A (en) * | 1970-01-07 | 1974-08-13 | Du Pont | Catalytic synthesis of substituted pyridines from acetylenes and nitriles |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4159382A (en) * | 1978-06-28 | 1979-06-26 | The Dow Chemical Company | Process for preparing picolylamine |
| US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| SE8204879D0 (sv) * | 1982-08-26 | 1982-08-26 | Haessle Ab | Novel chemical intermediates |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| IL71664A (en) * | 1983-05-03 | 1987-11-30 | Byk Gulden Lomberg Chem Fab | Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same |
| HU191756B (en) * | 1983-05-03 | 1987-04-28 | Byk Gulden Lomberg Chem Fab | Process for preparing new fluoro-alkoxy-benzimidazole derivatives |
| DE3415971A1 (de) * | 1983-05-03 | 1984-11-08 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Acylierte benzimidazole, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel |
| JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| CN85103357A (zh) * | 1985-05-13 | 1986-11-12 | 霍夫曼·拉罗奇有限公司 | 三环咪唑衍生物及其酸加成盐的制法 |
| SE8504409D0 (sv) * | 1985-09-24 | 1985-09-24 | Haessle Ab | Novel chemical intermediates |
| CA1276017C (en) * | 1986-02-13 | 1990-11-06 | Takeda Chemical Industries, Ltd. | Sulfenamide derivatives and their production |
| JPH0717631B2 (ja) * | 1986-03-04 | 1995-03-01 | 武田薬品工業株式会社 | ピリジニウム誘導体およびその製造法 |
| US4739057A (en) * | 1986-06-30 | 1988-04-19 | Stauffer Chemical Co. | Process for converting organo-hydroxyl compounds to halides |
| FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
| DE3837411A1 (de) * | 1987-11-13 | 1989-06-01 | Hoechst Ag | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
-
1988
- 1988-11-15 AT AT0278988A patent/AT391693B/de not_active IP Right Cessation
- 1988-11-30 DE DE3840372A patent/DE3840372A1/de not_active Withdrawn
-
1989
- 1989-10-23 ES ES89119640T patent/ES2053906T3/es not_active Expired - Lifetime
- 1989-10-23 DE DE8989119640T patent/DE58903808D1/de not_active Expired - Fee Related
- 1989-10-23 EP EP89119640A patent/EP0369208B1/de not_active Expired - Lifetime
- 1989-10-23 AT AT89119640T patent/ATE86978T1/de active
- 1989-10-30 IL IL92152A patent/IL92152A/xx not_active IP Right Cessation
- 1989-10-31 ZA ZA898273A patent/ZA898273B/xx unknown
- 1989-11-03 NZ NZ231252A patent/NZ231252A/en unknown
- 1989-11-06 NO NO89894410A patent/NO894410L/no unknown
- 1989-11-07 US US07/432,874 patent/US5066810A/en not_active Expired - Fee Related
- 1989-11-09 PH PH39501A patent/PH25813A/en unknown
- 1989-11-10 CA CA002002757A patent/CA2002757A1/en not_active Abandoned
- 1989-11-13 KR KR1019890016381A patent/KR900007803A/ko not_active Withdrawn
- 1989-11-13 YU YU02163/89A patent/YU216389A/xx unknown
- 1989-11-13 FI FI895389A patent/FI895389A7/fi not_active Application Discontinuation
- 1989-11-14 PT PT92307A patent/PT92307B/pt not_active IP Right Cessation
- 1989-11-14 DK DK568989A patent/DK568989A/da not_active Application Discontinuation
- 1989-11-14 DD DD89334567A patent/DD284877A5/de not_active IP Right Cessation
- 1989-11-14 HU HU895899A patent/HU207995B/hu not_active IP Right Cessation
- 1989-11-14 CS CS896438A patent/CS276357B6/cs unknown
- 1989-11-14 CN CN89108549A patent/CN1042705A/zh active Pending
- 1989-11-14 JP JP1294101A patent/JPH02180868A/ja active Pending
- 1989-11-14 SU SU894742390A patent/SU1745121A3/ru active
- 1989-11-14 AU AU44657/89A patent/AU628100B2/en not_active Ceased
-
1993
- 1993-03-18 GR GR920402814T patent/GR3007391T3/el unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004506716A (ja) * | 2000-08-25 | 2004-03-04 | バイエル・クロツプサイエンス・エス・アー | ２−アミノエチルピリジンの調製方法 |
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