JP7413456B2 - 心臓弁封止デバイスおよびその送達デバイス - Google Patents
心臓弁封止デバイスおよびその送達デバイス Download PDFInfo
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- JP7413456B2 JP7413456B2 JP2022118726A JP2022118726A JP7413456B2 JP 7413456 B2 JP7413456 B2 JP 7413456B2 JP 2022118726 A JP2022118726 A JP 2022118726A JP 2022118726 A JP2022118726 A JP 2022118726A JP 7413456 B2 JP7413456 B2 JP 7413456B2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/246—Devices for obstructing a leak through a native valve in a closed condition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2463—Implants forming part of the valve leaflets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2466—Delivery devices therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Description
人工スペーサデバイスが、スペーサ本体および少なくとも1つのアンカを備える。本体は、天然僧帽弁開口部内に位置決めされることにより天然弁尖同士の間におけるより効果的な封止をもたらして僧帽弁逆流を防止または最小限に抑えるのを補助するように構成される。本体は、血液不透過性であり、心室収縮期の間に本体側部の周囲で天然弁尖を閉じさせて左心室から左心房内に血液が流れ戻るのを阻止し得る構造を備え得る。本明細書では、本体は時としてスペーサと呼ばれる。なぜならば、本体は、本来的に完全には閉じない適切に機能できない天然僧帽弁尖同士の間の空間を充填し得るからである。
人工インプラントデバイス(例えば人工スペーサデバイス)を経皮的に送達するために使用される送達システムおよび/または送達装置は、誘導シース、1つまたは複数のカテーテル(例えば外方カテーテル、ガイドカテーテルおよび/またはインプラントカテーテル)、および他のデバイスを備え得る。一般的には、他のデバイス(例えばカテーテル)を患者の体内に導入するためのアクセスポイントを与える誘導シースが、患者の体内に挿入され得る。例えば、経中隔手技の最中に、誘導シースは、外方カテーテルが挿通され得る患者の右大腿静脈を通して挿入され得る。外方カテーテルは、大腿静脈を通して大静脈を通り右心房内に前進され得る。次いで、中隔が外方カテーテルで穿刺され、それにより外方カテーテルは左心房内に延在する。次いで、外方カテーテルは、中隔開口に留められ得る。
図131~図133は、人工心臓弁4600の例示の実施形態を示す。人工弁4600は、ステントまたはフレーム4602(図133)と、フレーム4602により支持されその内部に固定される弁尖アセンブリ4604と、フレーム4602の複数部分を覆うカバー4606とを備え得る。弁尖アセンブリ4604は、生体材料(例えばウシ、ブタ、もしくはウマの心膜組織などの心膜組織)または合成材料(例えばポリウレタン)から作製された1つまたは複数の組織弁尖4608(図示する実施形態では3つ)を備え得る。弁尖4608は、人工弁4600を通して血液を一方向に流し、逆方向への血流を阻止し得るように構成される。図131では、弁尖4608は、実線で示される場合には血流を阻止するための閉位置を示し、破線で示される場合には人工弁4600を通り血液を流し得る開位置を示す。
本明細書においては、この説明のために、本開示の実施形態の特定の態様、利点、および新規の特徴が説明される。開示される方法、装置、およびシステムは、どのような意味においても限定的なものとして解釈されるべきではない。逆に、本開示は、単独におけるならびに相互の様々な組合せおよび下位組合せにおける、様々な開示の実施形態の全ての新規および非自明な特徴および態様に関する。これらの方法、装置、およびシステムは、それらのいかなる特定の態様または特徴または組合せにも限定されず、開示される実施形態は、いかなる1つまたは複数の特定の利点が存在するまたは問題が解消されることも必須としない。
12 心室部分
14 スペーサ本体
16 内方シャフト
18 カラー
20 心室アンカ
22 端部キャップ
24 カラーまたはナット
26 外方シャフトまたはスリーブ
28 環状金属フレーム
30 血液不透過性繊維
100 植込み可能人工デバイス
102 心室アンカ
104 スペーサ本体
106 ねじ山付きシャフト
108 近位ナット
110 第1の環状カラー
112 第2の環状カラー
114 ストラット
116 遠位ストッパ
118 停止部材
200 植込み可能人工デバイス
202 送達装置
204 拡張可能スペーサ本体
206 心室アンカ
208 シャフト
210 ナット
212 外方カテーテル
214 インプラントカテーテル
216 送達シース
218 ナット支持シャフト
220 トルクシャフト
222 中隔
224 左心房
226 ガイドワイヤ
228 弁尖
300 植込み可能人工デバイス
302 心室部分
304 スペーサ本体
306 シャフト
308 近位端部
310 アンカ
312 送達装置
314 デバイスカテーテル
316 送達シース
318 シャフト
320 ガイドワイヤ
322 中隔
324 左心房
326 僧帽弁尖
328 左心室
400 植込み可能人工デバイス
402 心室端部部分
404 スペーサ本体
406 シャフト
408 近位端部部分
410 アンカ
412 ワイヤ、縫合糸、テザー、または弦
414 クリップ
416 摩擦要素
418 遠位端部
420 近位端部
422 中間部分
424 矢印方向
500 植込み可能人工デバイス
502 心室部分
504 スペーサ本体
506 内方シャフト
508 遠位端部
510 近位端部
512 心室アンカ
514 端部キャップ、遠位スリーブ
516 中間スリーブ
518 近位スリーブまたはシャフト
520 シース
522 開口
600 植込み可能人工デバイス
602 内方シャフト
604 端部キャップ
606 編組部分
608 外方シャフト
610 アンカ部分
612 本体部分
614 下方脚部
616 上方脚部
618 接合部
620 連結スリーブ
622 インプラントカテーテル
624 送達シース
700 植込み可能人工デバイス
702 心室アンカ
704 スペーサ本体
706 アンカ作動ライン
708 プルワイヤ
710 カラー
712 弁尖保持要素
714 編組部分
716 第1の端部
718 天然弁尖
800 植込み可能人工デバイス
802 心室アンカ
804 スペーサ本体
806 シャフト
808 第1の環状カラー
810 第2の環状カラー
812 相互連結ストラット
814 チューブ
816 プルワイヤ
818 ねじ山付きボルト
820 ワッシャ
822 シャフトまたはシム支持スリーブ
824 ナット
826 ナット支持レール
828 外部切欠部または溝
830 周方向リブ
832 無開口部分またはスパイン
834 非切断移行セクション
836 天然僧帽弁尖
838 第1の切断セクション
840 第2の切断セクション
842 第1の近位端部
844 第2の遠位端部
846 矢印方向
900 植込み可能人工デバイス
904 端部キャップ
906 編組部分
910 アンカ
912 スペーサ本体
914 下方脚部
916 上方脚部
1000 植込み可能人工デバイス
1002 心室アンカ
1004 スペーサ本体
1008 第1の環状カラー
1010 第2の環状カラー
1012 ストラット
1014 チューブ
1016 リブ
1018 無開口部分またはスパイン
1020 近位端部
1100 植込み可能人工デバイス
1102 心室部分
1104 スペーサ本体
1106 内方シャフト
1108 外方シャフト
1110 外方アンカ部材
1112 内方アンカ部材
1114 横部材
1116 第1の枢動可能継手
1118 第2の枢動可能継手
1120 矢印
1122 第3の枢動可能継手
1124 第4の枢動可能継手
1126 連結要素
1128 血液不透過性繊維
1130 弁尖
1200 植込み可能人工デバイス
1202 アンカ
1204 矢印
1206 シャフト
1208 スリーブ
1210 外方部材
1212 内方部材
1214 横部材
1216 第1の枢動可能継手
1218 第2の枢動可能継手
1220 第3の枢動可能継手
1222 第4の枢動可能継手
1224 開口
1300 可撓性人工インプラント送達デバイス
1302 インプラントカバーまたはシース
1304 可撓性径方向拡張性バスケット部分
1306 中間シャフト
1308 バスケット拡張機構
1310 近位シャフト
1312 操縦制御部材
1314 ガスケット拡張ワイヤ
1316 操縦制御ワイヤ
1318 第1の遠位端部
1320 第2の近位端部
1322 第1の遠位端部
1324 第2の近位端部
1326 インプラントルーメンまたは作用ルーメン
1328 ワイヤルーメン
1330 径方向延在側部開口またはポート
1332 第1の遠位セクション
1334 第2の近位セクション
1338 遠位ナット
1340 近位ナット
1342 外方ナットまたはスリーブ
1344 第1の雌ねじ山
1346 第2の雌ねじ山
1348 インプラントルーメン
1350 側部開口またはポート
1352 制御ハンドル
1354 スリーブ
1356 球状または少なくとも部分的に球状の外方表面
1358 ソケット
1360 軸方向に延在する開口
1362 端部キャップまたはフェルール
1364 人工スペーサデバイス
1366 僧帽弁
1368 心臓
1370 外方カテーテル
1371 左心房
1372 天然弁尖
1374 矢印
1376 矢印方向
1378 矢印方向
1400 操縦可能人工インプラント送達デバイス
1402 内方シャフト
1404 中間シャフト
1406 外方シャフト
1408 制御部材
1410 引張装置
1412 止血シール
1414 ボール
1416 ハンドル
1418 リング
1420 環状切欠部または溝
1422 ナットガイドアダプタ
1424 ドライブナット
1426 ストッパワッシャ
1428 ワイヤ張力調節ノブ
1430 調節ナットワッシャ
1432 端部キャップ
1436 摺動ノッチまたはポート
1438 スロット付き金属チューブ
1440 スパイン部分
1442 ストラット
1444 環状カラー
1446 開口、タブ
1448 軸方向セクション
1450 軸方向セクション
1452 軸方向セクション
1454 軸方向に延在する列
1454a 軸方向に延在する列
1454b 軸方向に延在する列
1454c 軸方向に延在する列
1454d 軸方向に延在する列
1456 遠位端部
1500 制御部材
1502 ボール
1504 ソケット
1504a 第1のソケット部分
1504b 第2のソケット部分
1506 クリップ
1508 凹状部分
1510 突出部
1512 ボール接触表面
1514 溝またはスロット
1516 タブ
1518 溝
1520 溝
1522 内方開口またはルーメン
1526 固定機構
1528 矢印方向
1600 制御部材
1602 ボール
1604 ソケット
1606 クリップ
1608 凹状部分
1610 ロッドまたはシャフト
1612 ボール接触表面
1614 溝またはスロット
1616 タブ
1618 溝
1620 内方開口またはルーメン
1700 制御部材
1702 ボール
1704 ソケット部分
1706 クリップ
1708 ピンまたは突出部
1710 凹状部分
1712 ガイドレール
1714 トラックまたはチャネル
1800 制御部材
1802 ボール
1804 ソケット部分
1806 クリップ
1808 突出部
1810 凹部またはチャネル
1900 制御部材
1902 ボール
1904 ソケット部分
1906 ロック
1908 雄ねじ山部分
1910 フランジまたはハンドル部分
1912 ほぼ球体形状の内部表面
1914 ノブ
2000 ロックデバイス
2002 カプラまたはスリーブ
2004 ハウジング
2005 遠位シャフト部分
2006 留め具部分
2008 ルーメン
2010 雄ねじ山付きプラグ
2012 ヘッド部分またはノブ
2014 誘導シース
2016 外方カテーテル
2100 カテーテル位置ロックデバイス
2102 固定部分
2104 可動部分
2106 開口
2108 軸方向延在スリーブ
2110 切欠部または溝
2112 開口
2114 軸方向延在ピン
2200 カテーテル位置ロックデバイス
2202 シャフト部分
2204 カム部分
2206 ハンドル部分
2208 開口またはルーメン
2210 フランジ部分
2212 環状凹状部分
2214 環状切欠部または溝
2216 オフセット開口
2218 開口
2220 雌ねじ山部分
2300 カテーテル位置ロックデバイス
2302 ロックスリーブ
2304 キーシャフトまたはチューブ
2306 軸方向延在開口
2308 タブまたはピン
2310 溝または切欠部
2312 中間カテーテルまたはガイドカテーテル
2400 人工インプラント送達デバイス
2402 外方シャフト
2404 環状カラーまたはコレット
2406 内方シャフト
2408 スリーブ部分
2410 プロングまたは歯
2412 突出部
2414 人工スペーサデバイス
2416 アンカ
2418 インプラントカバーまたはシース
2420 天然弁尖
2500 環状カラーまたはコレット
2502 スリーブ
2504 歯
2506 突出部
2600 人工インプラント送達デバイス
2602 環状カラーまたはコレット
2604 内方シャフト
2606 スリーブ部分
2608 プロングまたは歯
2610 突出部
2612 環状カラー
2614 開口
2700 人工インプラント送達デバイス
2702 外方シャフト
2704 環状カラーまたはコレット
2706 内方シャフト
2708 スリーブ部分
2710 プロングまたは歯
2712 突出部
2714 人工スペーサ
2716 アンカ
2718 環状カラー、インプラントカバーまたはシース
2720 天然弁尖
2800 環状カラーまたはコレット
2802 スリーブ
2804 歯
2806 突出部
2900 送達デバイス
2901 非円形シャフト
2902 長軸
2904 短軸
3000 非円形送達デバイス
3002 シャフト
3100 人工デバイス
3102 環状本体
3104 アンカ
3106 摩擦強化材料
3200 人工デバイス
3202 環状本体
3204 繊維カバー
3206 アンカ
3208 突出部
3300 人工デバイス
3302 環状本体
3304 繊維カバー
3306 アンカ
3308 突出部
3400 アンカ
3402 かえしまたは突出部
3500 人工デバイス
3502 環状本体
3504 繊維カバー
3506 アンカ
3508 かえしまたは突出部
3600 人工デバイス
3602 環状本体
3604 アンカ
3606 スリーブ
3608 かえしまたは突出部
3700 人工デバイス
3702 環状本体
3704 アンカ
3706 スリーブ
3708 突出部
3710 中間部分
3800 人工デバイス
3802 環状本体
3804 アンカ
3806 スリーブ
3808 突出部
3810 中間部分
3812 外方延在突出部
3814 コイルばね
3900 人工デバイス
3902 環状本体
3904 アンカ
3906 スリーブ
3908 突出部
3916 外方湾曲ストラット部材
4000 人工デバイス
4002 環状本体
4004 アンカ
4006 スリーブ
4008 突出部
4010 中間部分
4012 外方延在突出部
4014 コイルばね
4016 端部部分
4018 コイル部分
4100 人工デバイス
4102 ほぼ球状または球根状の本体
4104 アンカ
4106 突出部
4108 第1の折曲り可能部分
4110 第2の折曲り可能部分
4112 下方リング
4200 人工デバイス
4202 ほぼ球状のまたは球根状の本体
4204 アンカ
4206 突出部
4208 第1の折曲り可能部分
4210 第2の折曲り可能部分
4212 下方リング
4214 スロットまたは開口
4300 人工デバイス
4302 ほぼ球状または球根状の本体
4304 アンカ
4308 第1の内方折曲り可能部分
4310 第2の外方折曲り可能部分
4312 下方リングまたはスリーブ
4314 下方端部
4316 上方端部
4400 操縦制御機構
4402a 近位制御ノブ
4402b 遠位制御ノブ
4404a 第1のシャフト
4404b 第2のシャフト
4404c 第3のシャフト
4404d 第4のシャフト
4406a 歯車
4406b 歯車
4408a プルワイヤ保持具
4408b プルワイヤ保持具
4408c プルワイヤ保持具
4408d プルワイヤ保持具
4410 ハウジング
4500 植込み可能人工デバイス
4502 スペーサ本体
4504 アンカ
4506 固定部材
4508 ロック要素
4510 近位端部部分
4512 遠位端部部分
4514 近位端部部分
4516 自由遠位端部部分
4518 接合部分
4520 ヒンジ部分
4522 突出部
4600 人工心臓弁
4602 ステントまたはフレーム
4604 弁尖アセンブリ
4606 カバー
4608 組織弁尖
4610 環状本体
4612 第1のアンカ
4614 第2のアンカ
4700 フレーム
4702 環状本体
4704 第1のアンカ
4704a アンカ
4704b アンカ
4706 第2のアンカ
4708 タブまたはスリーブ
4708a タブまたはスリーブ
4708b タブまたはスリーブ
4710 第1の端部
4712a 第1の端部部分
4712b 第1の端部部分
4714a 第2の端部部分
4714b 第2の端部部分
4716 頂部または接合部
Claims (8)
- 天然心臓弁尖に接続するために構成された植込み可能人工デバイスであって、
心臓の天然弁尖間に配されるように構成されたスペーサ本体と;
前記スペーサ本体に結合された一対のアンカであって、前記一対のアンカの各アンカが、内方アンカ部材及び外方アンカ部材を備える、一対のアンカと;を備え、
各外方アンカ部材が、前記天然心臓弁尖のうちの対応するものの心室表面に対して配されるように構成され、
前記一対のアンカの各アンカが、前記内方アンカ部材と前記外方アンカ部材との間の前記天然弁尖のうちの一つを固定するように構成され、
前記スペーサ本体のサイズは、前記スペーサ本体が前記天然弁尖間に配され、前記天然心臓弁尖が前記一対のアンカの各アンカの前記内方アンカ部材と前記外方アンカ部材との間で固定された後に調整されるように構成される、植込み可能人工デバイス。 - 前記デバイスが、前記スペーサ本体を拡張する及び収縮することによって様々な癒合ラインに対応するように構成される、請求項1に記載の植込み可能人工デバイス。
- 前記スペーサ本体のサイズの調節機能が、中心及び偏心ジェット僧帽弁逆流の両方に使用するように構成される、請求項1に記載の植込み可能人工デバイス。
- 前記スペーサ本体が、心室と心房との間の開口部を2つの開口部に区分するように構成される、請求項1から3のいずれか一項に記載の植込み可能人工デバイス。
- 前記スペーサ本体が、編組された自己拡張性金属糸の単一片から作製される、請求項1に記載の植込み可能人工デバイス。
- 前記スペーサ本体が、血液不透過性材料で覆われる、請求項1から5のいずれか一項に記載の植込み可能人工デバイス。
- 前記スペーサ本体は、前記スペーサ本体の端部同士を軸方向に圧迫することにより、前記スペーサ本体が軸方向に短縮され、前記スペーサ本体が径方向に拡張されるように構成される、請求項1から6のいずれか一項に記載の植込み可能人工デバイス。
- 請求項1から7のいずれか一項に記載の植込み可能人工デバイスと;
第1のシャフト及び第2のシャフトを有する送達装置と;を備え、
前記第2のシャフトに対する前記第1のシャフトの移動が、前記スペーサ本体に対して前記一対のアンカを動かす、アセンブリ。
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