JP7308148B2 - 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体 - Google Patents

溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体 Download PDF

Info

Publication number
JP7308148B2
JP7308148B2 JP2019541198A JP2019541198A JP7308148B2 JP 7308148 B2 JP7308148 B2 JP 7308148B2 JP 2019541198 A JP2019541198 A JP 2019541198A JP 2019541198 A JP2019541198 A JP 2019541198A JP 7308148 B2 JP7308148 B2 JP 7308148B2
Authority
JP
Japan
Prior art keywords
nanostructures
conjugate
detection
detection conjugate
target analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019541198A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020509349A (ja
Inventor
ビンセント チャン
サラ アン アンサー
ラジェシュ ケイ. メーラ
ケネス ピー. アロン
Original Assignee
ゾエティス サービシズ リミテッド ライアビリティ カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ゾエティス サービシズ リミテッド ライアビリティ カンパニー filed Critical ゾエティス サービシズ リミテッド ライアビリティ カンパニー
Publication of JP2020509349A publication Critical patent/JP2020509349A/ja
Priority to JP2023065285A priority Critical patent/JP2023099008A/ja
Application granted granted Critical
Publication of JP7308148B2 publication Critical patent/JP7308148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • G01N21/554Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2019541198A 2017-01-30 2018-01-30 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体 Active JP7308148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023065285A JP2023099008A (ja) 2017-01-30 2023-04-13 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762451932P 2017-01-30 2017-01-30
US62/451,932 2017-01-30
PCT/US2018/015981 WO2018140953A1 (en) 2017-01-30 2018-01-30 Solution-based plasmon specific-binding partner assays and metallic nanostructures

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023065285A Division JP2023099008A (ja) 2017-01-30 2023-04-13 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体

Publications (2)

Publication Number Publication Date
JP2020509349A JP2020509349A (ja) 2020-03-26
JP7308148B2 true JP7308148B2 (ja) 2023-07-13

Family

ID=62978809

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019541198A Active JP7308148B2 (ja) 2017-01-30 2018-01-30 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体
JP2023065285A Pending JP2023099008A (ja) 2017-01-30 2023-04-13 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023065285A Pending JP2023099008A (ja) 2017-01-30 2023-04-13 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体

Country Status (11)

Country Link
US (2) US11977072B2 (https=)
EP (1) EP3574308A4 (https=)
JP (2) JP7308148B2 (https=)
KR (3) KR102486615B1 (https=)
CN (3) CN118275398A (https=)
AU (2) AU2018212009B2 (https=)
CA (1) CA3051465A1 (https=)
IL (2) IL268238B (https=)
MX (3) MX2019008970A (https=)
NZ (1) NZ796662A (https=)
WO (1) WO2018140953A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
EP4465021A3 (en) 2015-08-04 2025-02-26 Zoetis Services LLC Signal amplification in solution-based plasmonic specific-binding partner assays
US11299777B2 (en) 2016-04-04 2022-04-12 Nat Diagnostics, Inc. Isothermal amplification components and processes
US9617587B1 (en) 2016-04-04 2017-04-11 Nat Diagnostics, Inc. Isothermal amplification components and processes
WO2018140953A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures
EP3873977A4 (en) * 2018-11-01 2022-07-13 NB Postech Nitrocellulose membrane comprising non-covalently attached organic nanostructured molecule
GB2590485B (en) * 2019-12-19 2022-04-13 Vidya Holdings Ltd Nanoparticle conjugation
US11609229B2 (en) 2020-04-30 2023-03-21 Mytech Co. Ltd. Fluorescence counting system for quantifying viruses or antibodies on an immobilized metal substrate by using an antigen-antibody reaction
JP7589532B2 (ja) * 2020-12-14 2024-11-26 日油株式会社 イムノクロマト測定法用増感剤及び測定法
CA3215851A1 (en) * 2021-04-21 2022-10-27 Udayan Kanade System and method for simulating a localized surface plasmon resonance (lspr) spectrometer
CN114480591B (zh) * 2022-03-09 2022-11-08 武汉爱博泰克生物科技有限公司 一种用于一步法qpcr试剂的冻干保护剂及其应用
WO2023224100A1 (ja) * 2022-05-18 2023-11-23 公立大学法人大阪 糖タンパク質を検出するためのキット
WO2024075847A1 (ja) * 2022-10-06 2024-04-11 積水メディカル株式会社 非特異反応抑制剤、非特異反応抑制剤の使用方法、非特異反応抑制方法、生化学的測定用試薬、検体前処理液、及び生化学的測定用試薬キット
CN116183901B (zh) * 2023-01-04 2025-04-18 烟台大学 一种基于环糊精-金刚烷化铱络合物主客体组装标记的蛋白标记物荧光检测方法
CN118311253A (zh) * 2023-01-09 2024-07-09 广州达安基因股份有限公司 检测新型冠状病毒的检测卡的制备方法及检测卡
CN120741863B (zh) * 2025-06-06 2026-01-06 上海太阳生物技术有限公司 蛋白c检测试剂

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003149244A (ja) 2001-11-07 2003-05-21 Azwell Inc 免疫反応におけるプロゾーン現象抑制方法及び免疫反応測定用試薬
JP2008527332A (ja) 2004-12-31 2008-07-24 ジェネンテック・インコーポレーテッド 非ヒト血清中におけるヒト抗体の検出
US20100136566A1 (en) 2008-12-03 2010-06-03 Abaxis, Inc. Lateral flow strip assay with immobilized conjugate
JP2010537155A (ja) 2007-03-20 2010-12-02 ベクトン・ディキンソン・アンド・カンパニー 表面増強ラマン分光法(sers)活性粒子を使用するアッセイ
JP2011525966A (ja) 2008-03-20 2011-09-29 アバクシス, インコーポレイテッド ゾル粒子特異的結合アッセイの多波長分析
JP2012215472A (ja) 2011-03-31 2012-11-08 Fujifilm Corp 生体分子検出装置および生体分子検出方法
WO2014020293A1 (en) 2012-07-31 2014-02-06 Imperial Innovations Limited Assay
WO2014132833A1 (ja) 2013-03-01 2014-09-04 富士レビオ株式会社 未感作ラテックス試薬の劣化防止方法
JP2014228385A (ja) 2013-05-22 2014-12-08 キヤノン株式会社 免疫試験方法および免疫試験キット
JP2015007652A (ja) 2009-10-30 2015-01-15 協和メデックス株式会社 検体中の測定対象成分の測定方法及び測定用キット
WO2015160923A1 (en) 2014-04-15 2015-10-22 Rutgers, The State University Of New Jersey Gold nanostar substrates for sers sensing in the femtomolar regime
JP2016510126A (ja) 2013-03-14 2016-04-04 ホリバ・エービーエックス・エスエーエス 関心対象のための新規のフロー分析方法

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US5186844A (en) 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5122284A (en) 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5413732A (en) 1991-08-19 1995-05-09 Abaxis, Inc. Reagent compositions for analytical testing
US5304348A (en) 1992-02-11 1994-04-19 Abaxis, Inc. Reagent container for analytical rotor
AU4047493A (en) 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
JP3706214B2 (ja) 1996-10-28 2005-10-12 株式会社三菱化学ヤトロン 免疫学的分析方法
US5939021A (en) 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
US6180415B1 (en) 1997-02-20 2001-01-30 The Regents Of The University Of California Plasmon resonant particles, methods and apparatus
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US7144627B2 (en) 1997-03-12 2006-12-05 William Marsh Rice University Multi-layer nanoshells comprising a metallic or conducting shell
JPH10282100A (ja) * 1997-04-11 1998-10-23 Sekisui Chem Co Ltd 測定方法及び測定キット
ATE417275T1 (de) * 1997-09-22 2008-12-15 Novartis Vaccines & Diagnostic Puffern zur stabilizierung von hcv antigenen
US6699724B1 (en) 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
JP3841559B2 (ja) 1998-07-07 2006-11-01 日東電工株式会社 免疫学的検査方法および免疫学的検査キット
JP2000028612A (ja) 1998-07-07 2000-01-28 Nitto Denko Corp 免疫学的検査方法および免疫学的検査キット
JP3298836B2 (ja) 1998-11-12 2002-07-08 アークレイ株式会社 検体分析用具
US6579726B1 (en) 1999-07-30 2003-06-17 Surromed, Inc. Instruments, methods and reagents for surface plasmon resonance
JP2001074742A (ja) * 1999-09-06 2001-03-23 Jsr Corp ラテックス免疫比濁法および測定キット
EP1236034A4 (en) 1999-11-12 2006-05-03 Surromed Inc PLASMON RESONANCE SURFACE BIODETECTION
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
WO2002059226A2 (en) 2000-11-03 2002-08-01 Wm. Marsh Rice University Partial coverage metal nanoshells and method of making same
US20030170618A1 (en) 2001-02-02 2003-09-11 Chien David Y. Buffers for stabilizing antigens
US7238472B2 (en) 2001-05-25 2007-07-03 Nanosphere, Inc. Non-alloying core shell nanoparticles
US20050037437A1 (en) 2001-09-14 2005-02-17 Reinhard Zeidler Identification of antigen by xenogenic, allogenic or autologous antibody-mediated precipitation
US7135054B2 (en) 2001-09-26 2006-11-14 Northwestern University Nanoprisms and method of making them
CN1417586A (zh) 2001-11-05 2003-05-14 福州市迈新生物技术开发公司 一种免疫检测信号放大系统和它的制备方法及其应用
US6970239B2 (en) 2002-06-12 2005-11-29 Intel Corporation Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate
US7212692B2 (en) 2002-11-08 2007-05-01 Ming Yan Multiple array surface plasmon resonance biosensor
KR20050083623A (ko) * 2002-12-10 2005-08-26 마쯔시다덴기산교 가부시키가이샤 면역반응 측정방법
JP4787938B2 (ja) 2003-03-28 2011-10-05 ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン 銀ナノ粒子を用いた検体検出用センサ
KR100531760B1 (ko) 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US20060240573A1 (en) 2003-07-29 2006-10-26 Lamdagen, Llc Optical system including nanostructures for biological or chemical sensing
GB0321937D0 (en) 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
EP1692514A4 (en) 2003-11-07 2008-04-09 Hepgenics Pty Ltd BINDING ASSAY COMPONENTS
JP4109205B2 (ja) 2004-01-07 2008-07-02 富士フイルム株式会社 被検体検出方法
EP1836495A2 (en) 2004-11-17 2007-09-26 BioVeris Corporation Electrochemiluminescent assay
CN1296492C (zh) 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
US8628727B2 (en) 2005-04-08 2014-01-14 Northwestern University Compositions, devices and methods for SERS and LSPR
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
EP1915610A4 (en) 2005-06-15 2010-05-19 Univ Maryland Biotech Inst BIOASSAYS WITH PLASMONIC SPREADING OF PRECIOUS METAL NANOSTRUCTURES
US20070092978A1 (en) 2005-10-20 2007-04-26 Ronald Mink Target ligand detection
JP5442179B2 (ja) 2005-10-21 2014-03-12 アルフレッサファーマ株式会社 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬
CA2627376C (en) 2005-10-25 2016-07-05 Donald Templeton Haynie Immunogenic compositions and methods of use
US7888043B2 (en) 2005-11-18 2011-02-15 The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention Modified cardiolipin and uses therefor
WO2007103802A2 (en) 2006-03-03 2007-09-13 William Marsh Rice University Nanorice particles: hybrid plasmonic nanostructures
JP4810304B2 (ja) 2006-05-12 2011-11-09 キヤノン株式会社 化学センサ素子及びその製造方法
JP2010533281A (ja) 2006-06-06 2010-10-21 ビバクタ、リミテッド 化学物質の検知方法
JP2008157652A (ja) 2006-12-21 2008-07-10 Yokogawa Electric Corp 電源装置
US8426152B2 (en) 2007-01-03 2013-04-23 Lamdagen Corporation Enzymatic assay for LSPR
JP2009150708A (ja) 2007-12-19 2009-07-09 Canon Inc 標的物質の検出方法及び検査キット
US8808420B2 (en) 2007-12-21 2014-08-19 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Process for preparing nanoparticles
JP2011508062A (ja) * 2007-12-28 2011-03-10 スリーエム イノベイティブ プロパティズ カンパニー 可撓性封入フィルムシステム
WO2010006201A2 (en) 2008-07-10 2010-01-14 Abaxis, Inc. Methods of reducing non-specific interaction in metal nanoparticle assays
US8313915B2 (en) 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
WO2010091293A1 (en) 2009-02-06 2010-08-12 The Regents Of The University Of California Plasmonic system for detecting binding of biological molecules
CA2753598C (en) 2009-02-27 2018-07-10 Beckman Coulter, Inc. Solution phase homogeneous assays
WO2010116346A1 (en) 2009-04-08 2010-10-14 National University Of Ireland, Galway Silver nanoplates
JP5563789B2 (ja) 2009-06-11 2014-07-30 富士フイルム株式会社 検出方法
AU2010322085B2 (en) 2009-11-17 2016-09-15 Zoetis Services Llc Peptides and methods for the detection of Lyme disease antibodies
JP6161291B2 (ja) 2009-11-20 2017-07-12 アバクシス, インコーポレイテッド エールリッヒア抗体の検出のためのペプチド、装置、および方法
WO2011065747A2 (ko) 2009-11-24 2011-06-03 한국생명공학연구원 나노입자를 이용한 미생물의 고속 검출방법
US9308582B2 (en) 2009-12-24 2016-04-12 Yi Sun Solution stable and chemically reactive metallic nanoparticles
EP2354792A1 (en) 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
DK2564203T3 (en) 2010-04-27 2017-08-21 Ventana Med Syst Inc Antibody-nanoparticle conjugates and methods for preparing and using such conjugates
US20130071619A1 (en) 2010-05-28 2013-03-21 Nippon Steel & Sumikin Chemical Co., Ltd. Metal fine-particle composite and method for fabricating the same
CN102023151B (zh) 2010-09-17 2013-01-02 江南大学 用拉曼光谱在金纳米棒端面自组装介导下检测微囊藻毒素的方法
WO2012077756A1 (ja) 2010-12-08 2012-06-14 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
JP5614278B2 (ja) 2010-12-24 2014-10-29 セイコーエプソン株式会社 センサーチップ、センサーチップの製造方法、検出装置
CN102103145B (zh) 2011-02-24 2013-01-16 南京基蛋生物科技有限公司 一种双放大系统的胶体金试纸条及其制备方法
US8697129B2 (en) 2011-03-02 2014-04-15 Imra America, Inc. Stable colloidal gold nanoparticles with controllable surface modification and functionalization
WO2012125693A2 (en) 2011-03-15 2012-09-20 Northwestern University Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same
CN102323422B (zh) * 2011-05-30 2014-03-12 中国科学院上海微系统与信息技术研究所 半定量同时检测cTnI和Myo的免疫层析试纸条及其制备
US20130230717A1 (en) 2011-09-02 2013-09-05 Washington University In St. Louis Copper nanostructures and methods for their preparation
US8758772B2 (en) 2011-11-04 2014-06-24 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
CH705758B1 (fr) 2011-11-15 2016-03-31 Metalor Technologies Int Nanoparticules cœur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules.
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
US9823246B2 (en) 2011-12-28 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon
US20130189793A1 (en) 2012-01-20 2013-07-25 Wei Qian Stable Colloidal Suspensions Of Gold Nanoconjugates And The Method For Preparing The Same
US20150017258A1 (en) 2012-01-31 2015-01-15 American University Of Cairo (Auc) Direct detection of disease biomarkers in clinical specimens using cationic nanoparticle-based assays & versatile and green methods for synthesis of anisotropic silver nanostructures
EP2625966A1 (en) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
TWI435843B (zh) 2012-04-27 2014-05-01 Univ Nat Taiwan 奈米顆粒的製造方法
WO2013169640A1 (en) 2012-05-05 2013-11-14 Academia Sinica Diaminobenzoic or ortho-phenylene diamine conjugated peptides as functional saccharide tagging reagents
BR112015008036B1 (pt) 2012-10-11 2022-09-13 Zoetis Services Llc População de peptídeos isolados, método para detectar em uma amostra um anticorpo, método para diagnosticar erliquiose monocítica e/ou granulocítica, método para detectar a presença de anticorpos e kit
CA2887687A1 (en) 2012-10-11 2014-04-17 Nanocomposix, Inc. Silver nanoplate compositions and methods
US9441301B2 (en) 2012-12-06 2016-09-13 Nanyang Technological University Method for forming a bimetallic core-shell nanostructure
JP2016512241A (ja) * 2013-03-14 2016-04-25 アボット・ラボラトリーズAbbott Laboratories 改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
BR112015023239A8 (pt) * 2013-03-14 2018-04-17 Abbott Lab ensaio de combinação de anticorpo-antígeno de hcv e métodos e composições para uso do mesmo
US20160120978A1 (en) 2013-06-05 2016-05-05 Purdue Research Foundation Titanium nitride plasmonic nanoparticles for clinical therapeutic applications
CN103335984B (zh) 2013-06-09 2015-10-28 清华大学 一种基于lspr的无实体壁微阵列芯片及其应用
CN105393119A (zh) 2013-07-30 2016-03-09 生物辐射实验室股份有限公司 用于免疫试验的多重封闭物珠
KR20160138059A (ko) 2014-02-26 2016-12-02 람다젠 코퍼레이션 향상된 검정 감도를 위한 디지털 lspr
US10518331B2 (en) 2014-07-11 2019-12-31 Northwestern University Synthesis of uniform anisotropic nanoparticles
CN105492605A (zh) 2014-08-01 2016-04-13 比科尔公司 用于免疫检验的病毒样颗粒、用于所述免疫检验的封闭剂、及包含它们的试剂盒
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CA2976963A1 (en) 2015-02-19 2016-08-25 Ionica Sciences Reagents and methods for detecting infectious diseases
WO2016170183A1 (en) 2015-04-24 2016-10-27 Pharmadiagnostics Nv Improved method of measuring an interaction between molecules
EP4465021A3 (en) 2015-08-04 2025-02-26 Zoetis Services LLC Signal amplification in solution-based plasmonic specific-binding partner assays
CN106290893B (zh) 2016-07-18 2018-09-25 南昌大学 一种基于纳米铂探针检测牛乳β-乳球蛋白及其致敏性残基的方法
WO2018140953A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003149244A (ja) 2001-11-07 2003-05-21 Azwell Inc 免疫反応におけるプロゾーン現象抑制方法及び免疫反応測定用試薬
JP2008527332A (ja) 2004-12-31 2008-07-24 ジェネンテック・インコーポレーテッド 非ヒト血清中におけるヒト抗体の検出
JP2010537155A (ja) 2007-03-20 2010-12-02 ベクトン・ディキンソン・アンド・カンパニー 表面増強ラマン分光法(sers)活性粒子を使用するアッセイ
JP2011525966A (ja) 2008-03-20 2011-09-29 アバクシス, インコーポレイテッド ゾル粒子特異的結合アッセイの多波長分析
US20100136566A1 (en) 2008-12-03 2010-06-03 Abaxis, Inc. Lateral flow strip assay with immobilized conjugate
JP2015007652A (ja) 2009-10-30 2015-01-15 協和メデックス株式会社 検体中の測定対象成分の測定方法及び測定用キット
JP2012215472A (ja) 2011-03-31 2012-11-08 Fujifilm Corp 生体分子検出装置および生体分子検出方法
WO2014020293A1 (en) 2012-07-31 2014-02-06 Imperial Innovations Limited Assay
WO2014132833A1 (ja) 2013-03-01 2014-09-04 富士レビオ株式会社 未感作ラテックス試薬の劣化防止方法
JP2016510126A (ja) 2013-03-14 2016-04-04 ホリバ・エービーエックス・エスエーエス 関心対象のための新規のフロー分析方法
JP2014228385A (ja) 2013-05-22 2014-12-08 キヤノン株式会社 免疫試験方法および免疫試験キット
WO2015160923A1 (en) 2014-04-15 2015-10-22 Rutgers, The State University Of New Jersey Gold nanostar substrates for sers sensing in the femtomolar regime

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Alpha Protein-Protein Interaction ユーザーガイド,株式会社パーキンエルマージャパン,2017年11月,https://www.perkinelmer.co.jp/Portals/0/resource/tech/tech_ls/protocol_collection/Alpha_Protein-Protein_Interaction_userguide.pdf
JANA; ET AL,CAPPING AGENT-FREE GOLD NANOSTARS SHOW GREATLY INCREASED VERSATILITY AND SENSITIVITY FOR BIOSENSING,ANALYTICAL CHEMISTRY,2015年02月27日,VOL:87,PAGE(S):3964-3972,https://pubs.acs.org/doi/10.1021/acs.analchem.5b00014
KOOIJ E.S.,From nanorods to nanostars: Turning the optical properties of gold nanoparticles,Colloids and Surfaces A: Physicochem. Eng. Aspects,2012年,Vol.413,Page.231-238
Yuwei Pei,Highly sensitive SERS-based immunoassay with simultaneous utilization of self-assembled substrates of gold nanostars and aggregates of gold nanostars,J. Mater. Chem. B,2013年07月02日,Vol.1 No.32,Page.3992-3998
山口健吾,種々の金属ナノ粒子から成る高密度集合体の構築と表面増強ラマン散乱特性,日本化学会春季年会講演予稿集,2016年03月10日,Vol.96th,Page.RMBUNNO.3PC-239

Also Published As

Publication number Publication date
AU2022246447B2 (en) 2024-12-19
US20220091113A1 (en) 2022-03-24
KR102897521B1 (ko) 2025-12-09
KR102654470B1 (ko) 2024-04-05
WO2018140953A1 (en) 2018-08-02
IL268238B (en) 2022-09-01
AU2022246447A1 (en) 2022-11-03
EP3574308A1 (en) 2019-12-04
CN120446063A (zh) 2025-08-08
MX2023002376A (es) 2023-03-23
CN118275398A (zh) 2024-07-02
JP2020509349A (ja) 2020-03-26
US11977072B2 (en) 2024-05-07
IL295118A (en) 2022-09-01
CN110892250A (zh) 2020-03-17
KR20190112783A (ko) 2019-10-07
BR112019015664A2 (pt) 2020-03-31
US20250044286A1 (en) 2025-02-06
KR20230011477A (ko) 2023-01-20
AU2018212009A1 (en) 2019-08-15
EP3574308A4 (en) 2020-12-30
AU2018212009B2 (en) 2022-07-14
IL268238A (en) 2019-09-26
MX2023012379A (es) 2023-11-01
NZ796662A (en) 2026-03-27
IL295118B2 (en) 2025-06-01
IL295118B1 (en) 2025-02-01
NZ755886A (en) 2023-09-29
JP2023099008A (ja) 2023-07-11
KR102486615B1 (ko) 2023-01-11
CA3051465A1 (en) 2018-08-02
MX2019008970A (es) 2019-12-19
KR20240039224A (ko) 2024-03-26

Similar Documents

Publication Publication Date Title
JP7308148B2 (ja) 溶液ベースのプラズモン特異的結合パートナーアッセイおよび金属ナノ構造体
JP7818036B2 (ja) 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅
HK40128797A (zh) 基於溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
HK40112807A (zh) 基於溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
HK40106690A (zh) 基於溶液的等离子体特异性结合配偶体测定中的信号放大
BR112019015664B1 (pt) Métodos de detecção de um analito alvo em uma amostra, mistura de reação e método para preparar um conjugado compreendendo um parceiro de ligação e uma nanoestrutura metálica
NZ755886B2 (en) Solution-based plasmon specific-binding partner assays and metallic nanostructures

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210114

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20210401

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20210628

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20211119

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20211125

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220221

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220421

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220530

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20221214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230413

C60 Trial request (containing other claim documents, opposition documents)

Free format text: JAPANESE INTERMEDIATE CODE: C60

Effective date: 20230413

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20230421

C21 Notice of transfer of a case for reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C21

Effective date: 20230424

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230628

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230703

R150 Certificate of patent or registration of utility model

Ref document number: 7308148

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150