MX2023002376A - Ensayos de socio de union especifico de plasmon basados en solucion y nanoestructuras metalicas. - Google Patents

Ensayos de socio de union especifico de plasmon basados en solucion y nanoestructuras metalicas.

Info

Publication number
MX2023002376A
MX2023002376A MX2023002376A MX2023002376A MX2023002376A MX 2023002376 A MX2023002376 A MX 2023002376A MX 2023002376 A MX2023002376 A MX 2023002376A MX 2023002376 A MX2023002376 A MX 2023002376A MX 2023002376 A MX2023002376 A MX 2023002376A
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MX
Mexico
Prior art keywords
sample
solution
detection
binding partner
specific
Prior art date
Application number
MX2023002376A
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English (en)
Inventor
Rajesh K Mehra
Kenneth P Aron
Vincent Chiang
Sarah Ann Unser
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Zoetis Services Llc
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Publication date
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Publication of MX2023002376A publication Critical patent/MX2023002376A/es

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G01N21/554—Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a conjugados de socios de unión a nanoestructuras, así como a mezclas de reacción, dispositivos de detección de analito, y métodos de elaboración y utilización de los conjugados; en particular, la invención proporciona un método de detección de un analito objetivo en una muestra que comprende mezclar la muestra con un primer conjugado de detección y un segundo conjugado de detección en solución, en donde el primero y segundo conjugados de detección comprenden nanoestructuras metálicas acopladas a socios de unión que son capaces de unirse específicamente al analito objetivo si está presente en la muestra para formar un complejo entre el primer conjugado de detección, el analito, y el segundo conjugado de detección, en donde un cambio en una señal óptica luego de la formación del complejo indica la presencia del analito objetivo en la muestra.
MX2023002376A 2017-01-30 2019-07-29 Ensayos de socio de union especifico de plasmon basados en solucion y nanoestructuras metalicas. MX2023002376A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762451932P 2017-01-30 2017-01-30

Publications (1)

Publication Number Publication Date
MX2023002376A true MX2023002376A (es) 2023-03-23

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Family Applications (3)

Application Number Title Priority Date Filing Date
MX2019008970A MX2019008970A (es) 2017-01-30 2018-01-30 Ensayos de socio de unión específico de plasmón basados en solución y nanoestructuras metálicas.
MX2023012379A MX2023012379A (es) 2017-01-30 2019-07-29 Ensayos de socio de union especifico de plasmon basados en solucion y nanoestructuras metalicas.
MX2023002376A MX2023002376A (es) 2017-01-30 2019-07-29 Ensayos de socio de union especifico de plasmon basados en solucion y nanoestructuras metalicas.

Family Applications Before (2)

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MX2019008970A MX2019008970A (es) 2017-01-30 2018-01-30 Ensayos de socio de unión específico de plasmón basados en solución y nanoestructuras metálicas.
MX2023012379A MX2023012379A (es) 2017-01-30 2019-07-29 Ensayos de socio de union especifico de plasmon basados en solucion y nanoestructuras metalicas.

Country Status (10)

Country Link
US (1) US11977072B2 (es)
EP (1) EP3574308A4 (es)
JP (2) JP7308148B2 (es)
KR (3) KR102486615B1 (es)
CN (2) CN110892250A (es)
AU (2) AU2018212009B2 (es)
CA (1) CA3051465A1 (es)
IL (2) IL268238B (es)
MX (3) MX2019008970A (es)
WO (1) WO2018140953A1 (es)

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