EA201992748A1 - Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов - Google Patents

Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов

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Publication number
EA201992748A1
EA201992748A1 EA201992748A EA201992748A EA201992748A1 EA 201992748 A1 EA201992748 A1 EA 201992748A1 EA 201992748 A EA201992748 A EA 201992748A EA 201992748 A EA201992748 A EA 201992748A EA 201992748 A1 EA201992748 A1 EA 201992748A1
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Eurasian Patent Office
Prior art keywords
microorganisms
detection
analities
tracking
quantitative determination
Prior art date
Application number
EA201992748A
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English (en)
Inventor
Пол Зорнер
Эрик Дж. Матур
Джош Коллинз
Говард Белл
Скотт Алан Шибата
Original Assignee
Локус Агрикалче Айпи Компани, Ллк
Интеллиджент Материал Солюшнс Инк.
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Application filed by Локус Агрикалче Айпи Компани, Ллк, Интеллиджент Материал Солюшнс Инк. filed Critical Локус Агрикалче Айпи Компани, Ллк
Publication of EA201992748A1 publication Critical patent/EA201992748A1/ru

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02Food
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18Water
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/155Particles of a defined size, e.g. nanoparticles

Abstract

Настоящее изобретение обеспечивает способы и анализы для мультиплексного обнаружения аналитов, используя нанокристаллы, которые единообразны по морфологии, размеру и составу на основании их уникальных оптических характеристик. Описанные способы и анализы чрезвычайно пригодны для обнаружения микроорганизмов и/или агентов на основе микроорганизмов в комплексной пробе окружающей среды.
EA201992748A 2017-05-18 2018-05-17 Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов EA201992748A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762507895P 2017-05-18 2017-05-18
PCT/US2018/033222 WO2018213604A2 (en) 2017-05-18 2018-05-17 Diagnostic assays for detecting, quantifying, and/or tracking microbes and other analytes

Publications (1)

Publication Number Publication Date
EA201992748A1 true EA201992748A1 (ru) 2020-03-16

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EA201992748A EA201992748A1 (ru) 2017-05-18 2018-05-17 Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов

Country Status (17)

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US (2) US20200102602A1 (ru)
EP (1) EP3625563A4 (ru)
JP (1) JP2020521127A (ru)
KR (1) KR20200011456A (ru)
CN (1) CN111051884A (ru)
AU (1) AU2018269715A1 (ru)
BR (1) BR112019024200A2 (ru)
CA (1) CA3063714A1 (ru)
CL (1) CL2019003286A1 (ru)
CO (1) CO2019012771A2 (ru)
CR (1) CR20190574A (ru)
EA (1) EA201992748A1 (ru)
MX (1) MX2019013724A (ru)
PE (1) PE20200479A1 (ru)
PH (1) PH12019502558A1 (ru)
WO (1) WO2018213604A2 (ru)
ZA (1) ZA201907514B (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112313309A (zh) 2018-05-08 2021-02-02 轨迹农业Ip有限责任公司 用于增强植物根和免疫健康的基于微生物的产品
US20220228198A1 (en) * 2019-05-28 2022-07-21 Chan Zuckerberg Biohub, Inc. Method for multiplexed detection of nucleic acids using spectrally encoded beads
US11692989B2 (en) 2019-07-11 2023-07-04 Locus Solutions Ipco, Llc Use of soil and other environmental data to recommend customized agronomic programs
KR102388753B1 (ko) 2020-07-20 2022-04-20 광주과학기술원 유전영동 힘을 이용한 미생물 검출 장치
JP2023535895A (ja) * 2020-08-04 2023-08-22 ユニバーシティ・オブ・テクノロジー・シドニー 単一ナノ粒子の高次元フィンガープリント及び多重化デジタルアッセイにおけるその使用
CN112198133A (zh) * 2020-10-20 2021-01-08 上海洞舟实业有限公司 一种红外激光可视化检测仪的制备方法
CN112382510B (zh) * 2020-10-23 2022-07-05 华中科技大学 一种近红外光催化电极、制备方法及应用
KR102613085B1 (ko) 2020-11-26 2023-12-12 광주과학기술원 미생물 검출 시스템
CN112710845B (zh) * 2020-12-16 2023-07-07 北京热景生物技术股份有限公司 用于检测新冠状病毒中和抗体的试剂盒及检测方法
WO2022141230A1 (zh) * 2020-12-30 2022-07-07 北京化工大学 一种基于纳米金颗粒的多重核酸检测的方法
WO2022154094A1 (ja) * 2021-01-15 2022-07-21 旭化成株式会社 飲食品検体、環境検体、又は生体検体中の細菌の有無及び/又は存在量を検出するための方法及びキット
KR20230114664A (ko) 2022-01-25 2023-08-01 광주과학기술원 미지 용액내 미생물 농도 검출 소자

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6207392B1 (en) * 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
CA2344478C (en) * 1998-09-18 2010-03-30 Massachusetts Institute Of Technology Biological applications of semiconductor nanocrystals
DE60042738D1 (de) * 1999-05-07 2009-09-24 Life Technologies Corp Verfahren zum nachweis von analyten mit hilfe von halbleiternanokrystallen
US20020004246A1 (en) * 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
US20050208593A1 (en) * 2004-03-19 2005-09-22 Arizona Board Of Regents, Acting For And On Behalf Of Northern Arizona University Lateral flow diagnostic assay reader with radial cassette
CA2629076A1 (en) * 2005-11-09 2007-05-18 Primera Biosystems, Inc. Multiplexed quantitative detection of pathogens
WO2008105814A2 (en) * 2006-08-22 2008-09-04 Los Alamos National Security, Llc Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids
KR20080030555A (ko) * 2007-12-04 2008-04-04 에이전시 포 사이언스, 테크놀로지 앤드 리서치 폴리머 코팅 시약을 포함하는 신규 수용성 나노크리스탈 및이의 제조방법
WO2009137055A1 (en) * 2008-05-05 2009-11-12 Los Alamos National Security, Llc Nanocrystal-based lateral flow microarrays and low-voltage signal detection systems
US7910309B2 (en) * 2008-07-31 2011-03-22 Los Alamos National Security, Llc Multiplexed lateral flow microarray assay for detection of citrus pathogens Xylella fastidiosa and Xanthomonas axonopodis pv citri
US10054593B2 (en) * 2015-06-05 2018-08-21 Intelleigent Material Solutions, Inc. Multiplexed spectral lifetime detection of phosphors
US9577037B2 (en) * 2010-12-28 2017-02-21 Life Technologies Corporation Nanocrystals with high extinction coefficients and methods of making and using such nanocrystals
CN102199428B (zh) * 2011-04-11 2013-07-10 复旦大学 基于稀土掺杂的上转换纳米晶体的荧光编码微球及其制备方法
US20140170674A1 (en) * 2012-01-02 2014-06-19 Aimin He Membraine-Based Assay Devices Utilizing Time-Resolved Up-Converting Luminescence
US9995749B2 (en) * 2014-02-04 2018-06-12 Agency For Science, Technology And Research Method for detecting a target analyte

Also Published As

Publication number Publication date
US20230025938A1 (en) 2023-01-26
CL2019003286A1 (es) 2020-07-24
MX2019013724A (es) 2020-07-20
US20200102602A1 (en) 2020-04-02
CA3063714A1 (en) 2018-11-22
BR112019024200A2 (pt) 2020-06-02
PH12019502558A1 (en) 2021-01-25
JP2020521127A (ja) 2020-07-16
KR20200011456A (ko) 2020-02-03
ZA201907514B (en) 2022-03-30
EP3625563A2 (en) 2020-03-25
WO2018213604A2 (en) 2018-11-22
CR20190574A (es) 2020-04-03
AU2018269715A1 (en) 2020-01-16
CN111051884A (zh) 2020-04-21
PE20200479A1 (es) 2020-03-03
EP3625563A4 (en) 2021-02-24
WO2018213604A3 (en) 2018-12-27
CO2019012771A2 (es) 2020-04-01

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