EA201391627A1 - Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения - Google Patents

Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения

Info

Publication number
EA201391627A1
EA201391627A1 EA201391627A EA201391627A EA201391627A1 EA 201391627 A1 EA201391627 A1 EA 201391627A1 EA 201391627 A EA201391627 A EA 201391627A EA 201391627 A EA201391627 A EA 201391627A EA 201391627 A1 EA201391627 A1 EA 201391627A1
Authority
EA
Eurasian Patent Office
Prior art keywords
protein
analysis
lyzyloxidase
availability
methods
Prior art date
Application number
EA201391627A
Other languages
English (en)
Inventor
Виктория СМИТ
Джоан И. Адамкевич
Сьюзан К. Лиман
Джейсон Чиен
Сяомин Ли
Лисинь Шао
Джеффри Д. Борнстейн
Original Assignee
Джилид Байолоджикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46208194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201391627(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Джилид Байолоджикс, Инк. filed Critical Джилид Байолоджикс, Инк.
Publication of EA201391627A1 publication Critical patent/EA201391627A1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

В описании предложен анализ для обнаружения и/или определения количества полипептидов лизилоксидазоподобного белка 2 (LOXL2) в кровотоке у индивида. Данный анализ полезен для диагностических и прогностических применений, которые также предусмотрены.
EA201391627A 2011-06-01 2012-06-01 Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения EA201391627A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161492210P 2011-06-01 2011-06-01
US201161550895P 2011-10-24 2011-10-24
US201161578813P 2011-12-21 2011-12-21
PCT/US2012/040585 WO2012167181A1 (en) 2011-06-01 2012-06-01 Lysyl oxidase-like 2 assay and methods of use thereof

Publications (1)

Publication Number Publication Date
EA201391627A1 true EA201391627A1 (ru) 2014-08-29

Family

ID=46208194

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391627A EA201391627A1 (ru) 2011-06-01 2012-06-01 Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения

Country Status (24)

Country Link
US (3) US20140206017A1 (ru)
EP (1) EP2714744A1 (ru)
JP (3) JP2014523521A (ru)
KR (1) KR20140048156A (ru)
CN (1) CN103946241A (ru)
AP (1) AP2013007285A0 (ru)
AR (1) AR086657A1 (ru)
AU (2) AU2012261883A1 (ru)
BR (1) BR112013030682A2 (ru)
CA (1) CA2837534A1 (ru)
CL (1) CL2013003445A1 (ru)
CO (1) CO6940375A2 (ru)
CR (1) CR20130657A (ru)
EA (1) EA201391627A1 (ru)
EC (1) ECSP13013092A (ru)
IL (1) IL229631A0 (ru)
MA (1) MA35212B1 (ru)
MD (1) MD20130098A2 (ru)
MX (1) MX2013013905A (ru)
PE (1) PE20141450A1 (ru)
TW (1) TW201319572A (ru)
UY (1) UY34115A (ru)
WO (1) WO2012167181A1 (ru)
ZA (1) ZA201308812B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
AU2008299784B9 (en) 2007-08-02 2015-06-18 Gilead Biologics, Inc. LOX and LOXL2 inhibitors and uses thereof
US9107935B2 (en) 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
US8512990B2 (en) 2009-08-21 2013-08-20 Gilead Biologics, Inc. Catalytic domains from lysyl oxidase and LOXL2
MX2012009088A (es) 2010-02-04 2012-12-05 Gilead Biologics Inc Anticuerpos que se enlazan a lisil oxidasa-tipo2 (loxl2) y metodos de uso para los mismos.
EP2914632A1 (en) * 2012-10-30 2015-09-09 Gilead Sciences, Inc. Therapeutic and diagnostic methods related to lysyl oxidase-like 2 (loxl2)
US20150342943A1 (en) 2014-06-03 2015-12-03 Gilead Sciences, Inc. Methods of treating liver disease
CN106456772A (zh) * 2014-06-11 2017-02-22 吉利德科学公司 用于治疗心血管疾病的方法
MA41252A (fr) 2014-12-23 2017-10-31 Gilead Sciences Inc Formes solides d'un inhibiteur d'ask 1
JP2019510752A (ja) 2016-03-04 2019-04-18 ギリアード サイエンシーズ， インコーポレイテッド オートタキシン阻害剤の組成物及び合剤
US20170306050A1 (en) 2016-04-08 2017-10-26 Gilead Sciences, Inc. Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
GB201704206D0 (en) * 2017-03-16 2017-05-03 Nordic Bioscience As Lysyl oxidase like-2 assay
WO2023091479A1 (en) * 2021-11-17 2023-05-25 AmMax Bio, Inc. Detection and treatment of idiopathic pulmonary fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
AU2008299784B9 (en) * 2007-08-02 2015-06-18 Gilead Biologics, Inc. LOX and LOXL2 inhibitors and uses thereof
JP2010038735A (ja) * 2008-08-05 2010-02-18 Terumo Corp 腹膜機能の評価方法および腹膜機能評価用イムノクロマト試験紙
CN102711839A (zh) * 2009-08-21 2012-10-03 吉联亚生物科技有限公司 体内筛选试验
MX2012009088A (es) * 2010-02-04 2012-12-05 Gilead Biologics Inc Anticuerpos que se enlazan a lisil oxidasa-tipo2 (loxl2) y metodos de uso para los mismos.
KR101889363B1 (ko) * 2011-05-10 2018-08-17 보르그워너 인코퍼레이티드 가변 터빈 지오메트리를 갖는 터보차저

Also Published As

Publication number Publication date
AU2012261883A1 (en) 2013-05-02
EP2714744A1 (en) 2014-04-09
NZ618682A (en) 2016-04-29
MD20130098A2 (ru) 2014-06-30
UY34115A (es) 2013-01-03
AP2013007285A0 (en) 2013-11-30
WO2012167181A1 (en) 2012-12-06
CO6940375A2 (es) 2014-05-09
PE20141450A1 (es) 2014-11-06
US20120309020A1 (en) 2012-12-06
JP2016164578A (ja) 2016-09-08
MA35212B1 (fr) 2014-06-02
AR086657A1 (es) 2014-01-15
CA2837534A1 (en) 2012-12-06
CL2013003445A1 (es) 2014-07-25
ECSP13013092A (es) 2014-08-29
JP2014523521A (ja) 2014-09-11
AU2016244254A1 (en) 2016-11-03
TW201319572A (zh) 2013-05-16
JP2018049033A (ja) 2018-03-29
KR20140048156A (ko) 2014-04-23
IL229631A0 (en) 2014-01-30
US20140206017A1 (en) 2014-07-24
CN103946241A (zh) 2014-07-23
CR20130657A (es) 2014-05-16
ZA201308812B (en) 2014-08-27
US20170269085A1 (en) 2017-09-21
BR112013030682A2 (pt) 2016-12-06
AU2016244254B2 (en) 2018-10-18
MX2013013905A (es) 2014-05-14

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