BR112019005167A2 - método e kit para analisar uma amostra - Google Patents
método e kit para analisar uma amostraInfo
- Publication number
- BR112019005167A2 BR112019005167A2 BR112019005167A BR112019005167A BR112019005167A2 BR 112019005167 A2 BR112019005167 A2 BR 112019005167A2 BR 112019005167 A BR112019005167 A BR 112019005167A BR 112019005167 A BR112019005167 A BR 112019005167A BR 112019005167 A2 BR112019005167 A2 BR 112019005167A2
- Authority
- BR
- Brazil
- Prior art keywords
- analyzing
- kit
- sample
- suspected
- kits
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9406—Neurotransmitters
- G01N33/942—Serotonin, i.e. 5-hydroxy-tryptamine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/22—Haematology
- G01N2800/224—Haemostasis or coagulation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7095—Inflammation
Abstract
proveem-se, neste documento, métodos e kits para analisar uma amostra biológica obtida a partir de um indivíduo tendo, com suspeita de ter ou com risco de ter uma doença associada ao sistema de ativação por contato.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662395770P | 2016-09-16 | 2016-09-16 | |
US201762518367P | 2017-06-12 | 2017-06-12 | |
PCT/US2017/051755 WO2018053247A1 (en) | 2016-09-16 | 2017-09-15 | Metabolite biomarkers for diseases associated with the contact activation system |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112019005167A2 true BR112019005167A2 (pt) | 2019-07-02 |
Family
ID=59974882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112019005167A BR112019005167A2 (pt) | 2016-09-16 | 2017-09-15 | método e kit para analisar uma amostra |
Country Status (13)
Country | Link |
---|---|
US (2) | US11340237B2 (pt) |
EP (1) | EP3513197A1 (pt) |
JP (3) | JP7225090B2 (pt) |
KR (2) | KR102464380B1 (pt) |
CN (2) | CN117169508A (pt) |
AU (2) | AU2017325986B2 (pt) |
BR (1) | BR112019005167A2 (pt) |
CA (1) | CA3037157A1 (pt) |
CO (1) | CO2019002607A2 (pt) |
IL (1) | IL265199A (pt) |
MX (1) | MX2019002918A (pt) |
NZ (1) | NZ751481A (pt) |
WO (1) | WO2018053247A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL3096798T3 (pl) * | 2014-01-21 | 2021-07-26 | Takeda Pharmaceutical Company Limited | Białka wiążące kalikreinę osocza i ich zastosowanie w leczeniu obrzęku naczynioruchowego |
CN109716138B (zh) | 2016-09-16 | 2023-10-03 | 武田药品工业株式会社 | 用于接触活化系统相关的疾病的蛋白生物标记 |
EP3521828A1 (en) * | 2018-01-31 | 2019-08-07 | Centogene AG | Method for the diagnosis of hereditary angioedema |
CN110514772A (zh) * | 2019-08-09 | 2019-11-29 | 中国医学科学院基础医学研究所 | 透明肾细胞癌代谢标志物在肾细胞癌早期筛查和诊断产品中的应用 |
CN113495137A (zh) * | 2021-06-29 | 2021-10-12 | 江苏省中医院 | 两种代谢标志物单独或联合在制备诊断克罗恩病的试剂盒中的应用 |
CN117310059B (zh) * | 2023-11-30 | 2024-02-02 | 中国人民解放军总医院 | 用于早期诊断或监测克罗恩病的血浆代谢标志物组合及应用 |
Family Cites Families (43)
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US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
EP0739355B1 (en) | 1994-01-11 | 2004-09-08 | Dyax Corporation | Kallikrein-inhibiting "kunitz domain" proteins and analogues thereof |
US20040152633A1 (en) | 2001-05-31 | 2004-08-05 | Jorgensen Marianne Ulrich | Kunitz-type sequences and polypeptides |
ES2372978T3 (es) | 2002-06-07 | 2012-01-30 | Dyax Corp. | Polipéptido con dominio de kunitz modificado. |
US7153829B2 (en) * | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
EP1711828A2 (en) | 2004-01-28 | 2006-10-18 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with kallikrein 2 (klk2) |
EP1598428A1 (en) | 2004-05-18 | 2005-11-23 | Georg Dewald | Methods and kits to detect Hereditary angioedema type III |
ITMI20041963A1 (it) * | 2004-10-15 | 2005-01-15 | Luso Farmaco Inst | "antagonisti non-peptidici della bradichinina e loro composizioni farmaceutiche" |
EP1949105A4 (en) | 2005-10-11 | 2009-06-17 | Tethys Bioscience Inc | MARKERS ASSOCIATED WITH DIABETES AND METHODS OF USE THEREOF |
US7276480B1 (en) | 2005-12-30 | 2007-10-02 | Dyax Corp. | Prevention and reduction of blood loss |
WO2008016883A2 (en) * | 2006-07-31 | 2008-02-07 | Activesite Pharmaceuticals, Inc. | Inhibitors of plasma kallikrein |
WO2008019052A2 (en) | 2006-08-03 | 2008-02-14 | Numira Biosciences, Inc. | Methods and compositions for identifying biomarkers |
EP2118135A1 (en) | 2006-10-16 | 2009-11-18 | Bayer Schering Pharma AG | Crtac as a biomarker, therapeutic and diagnostic target |
EP2087359A1 (en) | 2006-10-16 | 2009-08-12 | Bayer Schering Pharma AG | Prss23 as a biomarker, therapeutic and diagnostic target |
US20110111394A1 (en) | 2006-10-16 | 2011-05-12 | Bayer Schering Pharma Aktiengesellschaft | Ctgf as a biomarker, therapeutic and diagnostic target |
WO2008046528A1 (en) | 2006-10-16 | 2008-04-24 | Bayer Healthcare Ag | Npr3 as a biomarker, therapeutic and diagnostic target |
US8088584B2 (en) | 2006-10-16 | 2012-01-03 | Bayer Schering Pharma Aktiengesellschaft | LTBP2 as a biomarker and diagnostic target |
WO2008046510A1 (en) | 2006-10-16 | 2008-04-24 | Bayer Healthcare Ag | Fn1 as a biomarker, therapeutic and diagnostic target |
WO2008046508A1 (en) | 2006-10-16 | 2008-04-24 | Bayer Healthcare Ag | Tgfb2 as a biomarker, therapeutic and diagnostic target |
FR2914066B1 (fr) * | 2007-03-20 | 2009-05-22 | Polyintell Sarl | Kit d'analyse comprenant au moins deux polymeres a empreintes moleculaires et au moins un marqueur, ainsi que le procede d'analyse l'utilisant |
CN105675892A (zh) | 2008-04-29 | 2016-06-15 | 赛凯米迪克斯股份有限公司 | 固相多分析物测试 |
WO2010045180A1 (en) * | 2008-10-13 | 2010-04-22 | Metabolon, Inc. | Biomarkers for inflammatory bowel disease and methods using the same |
DK2466312T3 (da) * | 2009-08-12 | 2020-01-13 | Human Metabolome Tech Inc | Phosphoethanolamine som biomarkør for depression |
WO2011051805A1 (en) | 2009-10-27 | 2011-05-05 | Anaxomics Biotech Sl | Methods and systems for identifying molecules or processes of biological interest by using knowledge discovery in biological data |
RU2012122180A (ru) * | 2009-10-30 | 2013-12-10 | Нестек С.А. | Способы диагностики синдрома раздраженного кишечника |
ES2532006T3 (es) | 2009-11-20 | 2015-03-23 | Pharnext | Nuevas herramientas de diagnóstico para la enfermedad de Charcot-Marie-Tooth |
PT2521568T (pt) | 2010-01-06 | 2018-10-26 | Dyax Corp | Proteínas de ligação à calicreína plasmática |
MX2012010852A (es) | 2010-03-23 | 2013-04-03 | Purdue Research Foundation | Deteccion temprana de cancer de mama recurrente, que utiliza el perfilado de metabolismo. |
KR102169651B1 (ko) | 2011-01-06 | 2020-10-23 | 다이액스 코포레이션 | 혈장 칼리크레인 결합 단백질 |
JP6679309B2 (ja) * | 2012-08-29 | 2020-04-15 | カリフォルニア インスティチュート オブ テクノロジー | 自閉症スペクトラム障害の診断および処置 |
US20140086825A1 (en) | 2012-09-24 | 2014-03-27 | William J. McFaul | Methods and kits for assessing, modulating and treating substances affecting bodily processes |
EP4234583A3 (en) | 2013-01-20 | 2024-01-24 | Takeda Pharmaceutical Company Limited | Evaluation and treatment of bradykinin-mediated disorders |
DK2946206T3 (en) | 2013-01-20 | 2019-04-15 | Dyax Corp | EVALUATION, ANALYSIS AND TREATMENT OF PKAL-MEDIATED DISORDERS |
BR112015022846A2 (pt) | 2013-03-14 | 2017-11-07 | Shire Human Genetic Therapies | uso de um composto para tratar ou prevenir um angioedema mediado pelo receptor b2 da bradicinina e formulação compreendendo o mesmo |
DK2970106T3 (en) * | 2013-03-15 | 2018-08-13 | Intrexon Corp | CONTAINING DIACYL HYDRAZINES |
CN105873951A (zh) | 2013-10-21 | 2016-08-17 | 戴埃克斯有限公司 | 用于确定血浆激肽释放酶系统生物标记的试验 |
EP2884282A1 (en) * | 2013-12-13 | 2015-06-17 | CONARIS research institute AG | Use of tryptophan as a biomarker for patient selection, dosing and therapy monitoring for pharmaceutical compositions targeting the intestinal microbiota in diseases featuring tryptophan deficiency |
AU2015321470B2 (en) | 2014-09-22 | 2018-11-15 | National Health Research Institutes | Use of 5-methoxytryptophan as diagnostic agent of inflammatory diseases |
BR112017020864A2 (pt) * | 2015-03-30 | 2018-07-10 | Dyax Corp | inibidores de calicreína plasmática e usos dos mesmos para a prevenção de ataque de angioedema hereditário |
EA201890478A1 (ru) | 2015-08-13 | 2018-07-31 | Дайэкс Корп. | Вакуумные пробирки для сбора крови, содержащие ингибиторы протеазы, для оценки активации контактной системы |
JP6570472B2 (ja) | 2016-03-30 | 2019-09-04 | 株式会社マンダム | 毛髪の損傷の評価方法 |
EP3513188A1 (en) | 2016-09-16 | 2019-07-24 | Dyax Corp. | Rna biomarkers for hereditary angioedema |
CN109716138B (zh) | 2016-09-16 | 2023-10-03 | 武田药品工业株式会社 | 用于接触活化系统相关的疾病的蛋白生物标记 |
-
2017
- 2017-09-15 KR KR1020197010802A patent/KR102464380B1/ko active IP Right Grant
- 2017-09-15 AU AU2017325986A patent/AU2017325986B2/en active Active
- 2017-09-15 US US16/333,101 patent/US11340237B2/en active Active
- 2017-09-15 CN CN202310782203.XA patent/CN117169508A/zh active Pending
- 2017-09-15 WO PCT/US2017/051755 patent/WO2018053247A1/en unknown
- 2017-09-15 NZ NZ751481A patent/NZ751481A/en unknown
- 2017-09-15 CA CA3037157A patent/CA3037157A1/en active Pending
- 2017-09-15 MX MX2019002918A patent/MX2019002918A/es unknown
- 2017-09-15 JP JP2019514825A patent/JP7225090B2/ja active Active
- 2017-09-15 CN CN201780057052.4A patent/CN109716137B/zh active Active
- 2017-09-15 KR KR1020227038426A patent/KR20220154245A/ko not_active Application Discontinuation
- 2017-09-15 EP EP17777137.5A patent/EP3513197A1/en active Pending
- 2017-09-15 BR BR112019005167A patent/BR112019005167A2/pt unknown
-
2019
- 2019-03-06 IL IL265199A patent/IL265199A/en unknown
- 2019-03-21 CO CONC2019/0002607A patent/CO2019002607A2/es unknown
-
2022
- 2022-04-25 US US17/728,285 patent/US20220365101A1/en active Pending
-
2023
- 2023-02-08 JP JP2023017898A patent/JP7451791B2/ja active Active
-
2024
- 2024-01-30 AU AU2024200561A patent/AU2024200561A1/en active Pending
- 2024-03-06 JP JP2024034012A patent/JP2024059990A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20190361036A1 (en) | 2019-11-28 |
US20220365101A1 (en) | 2022-11-17 |
NZ751481A (en) | 2024-02-23 |
AU2017325986B2 (en) | 2023-12-14 |
CA3037157A1 (en) | 2018-03-22 |
CO2019002607A2 (es) | 2019-03-29 |
KR102464380B1 (ko) | 2022-11-07 |
MX2019002918A (es) | 2019-07-18 |
CN109716137B (zh) | 2023-07-21 |
AU2017325986A1 (en) | 2019-04-04 |
JP2023058612A (ja) | 2023-04-25 |
EP3513197A1 (en) | 2019-07-24 |
JP7451791B2 (ja) | 2024-03-18 |
WO2018053247A1 (en) | 2018-03-22 |
US11340237B2 (en) | 2022-05-24 |
JP2019534446A (ja) | 2019-11-28 |
AU2024200561A1 (en) | 2024-02-15 |
IL265199A (en) | 2019-05-30 |
JP7225090B2 (ja) | 2023-02-20 |
KR20190053914A (ko) | 2019-05-20 |
JP2024059990A (ja) | 2024-05-01 |
KR20220154245A (ko) | 2022-11-21 |
CN117169508A (zh) | 2023-12-05 |
CN109716137A (zh) | 2019-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) |
|
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |