IL295118B2 - Solution-based plasmon specific-binding partner assays and metallic nanostructures - Google Patents

Solution-based plasmon specific-binding partner assays and metallic nanostructures

Info

Publication number
IL295118B2
IL295118B2 IL295118A IL29511822A IL295118B2 IL 295118 B2 IL295118 B2 IL 295118B2 IL 295118 A IL295118 A IL 295118A IL 29511822 A IL29511822 A IL 29511822A IL 295118 B2 IL295118 B2 IL 295118B2
Authority
IL
Israel
Prior art keywords
nanostructures
assay complex
conjugates
detection
antigen
Prior art date
Application number
IL295118A
Other languages
English (en)
Hebrew (he)
Other versions
IL295118B1 (en
IL295118A (en
Inventor
Vincent Chiang
Sarah Ann Unser
Rajesh K Mehra
Kenneth P Aron
Original Assignee
Zoetis Services Llc
Vincent Chiang
Sarah Ann Unser
Rajesh K Mehra
Kenneth P Aron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc, Vincent Chiang, Sarah Ann Unser, Rajesh K Mehra, Kenneth P Aron filed Critical Zoetis Services Llc
Publication of IL295118A publication Critical patent/IL295118A/en
Publication of IL295118B1 publication Critical patent/IL295118B1/en
Publication of IL295118B2 publication Critical patent/IL295118B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G01N21/554—Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL295118A 2017-01-30 2018-01-30 Solution-based plasmon specific-binding partner assays and metallic nanostructures IL295118B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762451932P 2017-01-30 2017-01-30
PCT/US2018/015981 WO2018140953A1 (en) 2017-01-30 2018-01-30 Solution-based plasmon specific-binding partner assays and metallic nanostructures

Publications (3)

Publication Number Publication Date
IL295118A IL295118A (en) 2022-09-01
IL295118B1 IL295118B1 (en) 2025-02-01
IL295118B2 true IL295118B2 (en) 2025-06-01

Family

ID=62978809

Family Applications (2)

Application Number Title Priority Date Filing Date
IL295118A IL295118B2 (en) 2017-01-30 2018-01-30 Solution-based plasmon specific-binding partner assays and metallic nanostructures
IL268238A IL268238B (en) 2017-01-30 2018-01-30 Tests for a specific plasmon-based solution for co-linking and metallic nanostructures

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL268238A IL268238B (en) 2017-01-30 2018-01-30 Tests for a specific plasmon-based solution for co-linking and metallic nanostructures

Country Status (11)

Country Link
US (2) US11977072B2 (https=)
EP (1) EP3574308A4 (https=)
JP (2) JP7308148B2 (https=)
KR (3) KR102486615B1 (https=)
CN (3) CN118275398A (https=)
AU (2) AU2018212009B2 (https=)
CA (1) CA3051465A1 (https=)
IL (2) IL295118B2 (https=)
MX (3) MX2019008970A (https=)
NZ (1) NZ796662A (https=)
WO (1) WO2018140953A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3489685T3 (fi) 2011-11-21 2023-12-21 Zoetis Services Llc Signaalin vahvistaminen lateraalivirtaus- ja vastaavissa immunomäärityksissä
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CA2991532C (en) 2015-08-04 2024-03-05 Abaxis, Inc. Signal amplification in solution-based plasmonic specific-binding partner assays
US9617587B1 (en) 2016-04-04 2017-04-11 Nat Diagnostics, Inc. Isothermal amplification components and processes
US11299777B2 (en) 2016-04-04 2022-04-12 Nat Diagnostics, Inc. Isothermal amplification components and processes
CN118275398A (zh) 2017-01-30 2024-07-02 硕腾服务有限责任公司 基于溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
KR20210125976A (ko) 2018-11-01 2021-10-19 주식회사 엔비포스텍 비-공유적으로 부착된 유기 나노구조화된 분자를 포함하는 니트로셀룰로스 막
GB2590485B (en) * 2019-12-19 2022-04-13 Vidya Holdings Ltd Nanoparticle conjugation
US11609229B2 (en) 2020-04-30 2023-03-21 Mytech Co. Ltd. Fluorescence counting system for quantifying viruses or antibodies on an immobilized metal substrate by using an antigen-antibody reaction
JP7589532B2 (ja) * 2020-12-14 2024-11-26 日油株式会社 イムノクロマト測定法用増感剤及び測定法
US20240211658A1 (en) * 2021-04-21 2024-06-27 Nicoya Lifesciences Inc. System and method for simulating a localized surface plasmon resonance(lspr) spectrometer
CN114480591B (zh) * 2022-03-09 2022-11-08 武汉爱博泰克生物科技有限公司 一种用于一步法qpcr试剂的冻干保护剂及其应用
US20250354991A1 (en) * 2022-05-18 2025-11-20 University Public Corporation Osaka Kit for detecting glycoprotein
EP4600649A1 (en) * 2022-10-06 2025-08-13 Sekisui Medical Co., Ltd. Non-specific reaction inhibitor, method for using non-specific reaction inhibitor, method for inhibiting non-specific reaction, biochemical measurement reagent, specimen pretreatment solution, and biochemical measurement reagent kit
CN116183901B (zh) * 2023-01-04 2025-04-18 烟台大学 一种基于环糊精-金刚烷化铱络合物主客体组装标记的蛋白标记物荧光检测方法
CN118311253A (zh) * 2023-01-09 2024-07-09 广州达安基因股份有限公司 检测新型冠状病毒的检测卡的制备方法及检测卡
CN120741863B (zh) * 2025-06-06 2026-01-06 上海太阳生物技术有限公司 蛋白c检测试剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110275061A1 (en) * 2007-03-20 2011-11-10 Kristin Weidemaier Assays using surface-enhanced raman spectroscopy (sers)-active particles

Family Cites Families (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US5122284A (en) 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5186844A (en) 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5413732A (en) 1991-08-19 1995-05-09 Abaxis, Inc. Reagent compositions for analytical testing
US5304348A (en) 1992-02-11 1994-04-19 Abaxis, Inc. Reagent container for analytical rotor
AU4047493A (en) 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
JP3706214B2 (ja) 1996-10-28 2005-10-12 株式会社三菱化学ヤトロン 免疫学的分析方法
US5939021A (en) 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
EP0979409B1 (en) 1997-02-20 2006-12-27 The Regents of the University of California Plasmon resonant particles, methods and apparatus
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US7144627B2 (en) 1997-03-12 2006-12-05 William Marsh Rice University Multi-layer nanoshells comprising a metallic or conducting shell
JPH10282100A (ja) * 1997-04-11 1998-10-23 Sekisui Chem Co Ltd 測定方法及び測定キット
AU9498098A (en) * 1997-09-22 1999-04-12 Chiron Corporation Buffers for stabilizing antigens
US6699724B1 (en) 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
JP2000028612A (ja) 1998-07-07 2000-01-28 Nitto Denko Corp 免疫学的検査方法および免疫学的検査キット
JP3841559B2 (ja) 1998-07-07 2006-11-01 日東電工株式会社 免疫学的検査方法および免疫学的検査キット
JP3298836B2 (ja) 1998-11-12 2002-07-08 アークレイ株式会社 検体分析用具
US6579726B1 (en) 1999-07-30 2003-06-17 Surromed, Inc. Instruments, methods and reagents for surface plasmon resonance
JP2001074742A (ja) * 1999-09-06 2001-03-23 Jsr Corp ラテックス免疫比濁法および測定キット
JP2003514224A (ja) 1999-11-12 2003-04-15 サーロメッド・インコーポレーテッド 表面プラズモン共鳴を使用するバイオセンシング
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
AU2002246587A1 (en) 2000-11-03 2002-08-06 Wm. Marsh Rice University Partial coverage metal nanoshells and method of making same
US20030170618A1 (en) * 2001-02-02 2003-09-11 Chien David Y. Buffers for stabilizing antigens
WO2002096262A2 (en) 2001-05-25 2002-12-05 Northwestern University Non-alloying core shell nanoparticles
US20050037437A1 (en) 2001-09-14 2005-02-17 Reinhard Zeidler Identification of antigen by xenogenic, allogenic or autologous antibody-mediated precipitation
US7135054B2 (en) 2001-09-26 2006-11-14 Northwestern University Nanoprisms and method of making them
CN1417586A (zh) 2001-11-05 2003-05-14 福州市迈新生物技术开发公司 一种免疫检测信号放大系统和它的制备方法及其应用
JP3851807B2 (ja) 2001-11-07 2006-11-29 アルフレッサファーマ株式会社 免疫反応におけるプロゾーン現象抑制方法及び免疫反応測定用試薬
US6970239B2 (en) 2002-06-12 2005-11-29 Intel Corporation Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate
US7212692B2 (en) 2002-11-08 2007-05-01 Ming Yan Multiple array surface plasmon resonance biosensor
KR20050083623A (ko) * 2002-12-10 2005-08-26 마쯔시다덴기산교 가부시키가이샤 면역반응 측정방법
JP4787938B2 (ja) 2003-03-28 2011-10-05 ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン 銀ナノ粒子を用いた検体検出用センサ
KR100531760B1 (ko) 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US20060240573A1 (en) 2003-07-29 2006-10-26 Lamdagen, Llc Optical system including nanostructures for biological or chemical sensing
GB0321937D0 (en) 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
JP2007510165A (ja) 2003-11-07 2007-04-19 ヘプゲニクス ピーティワイ リミティッド 結合アッセイ成分
JP4109205B2 (ja) 2004-01-07 2008-07-02 富士フイルム株式会社 被検体検出方法
JP2008521007A (ja) * 2004-11-17 2008-06-19 バイオヴェリス コーポレイション 電気化学発光測定法
CN1296492C (zh) 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
WO2006074076A1 (en) 2004-12-31 2006-07-13 Genentech, Inc. Detecting human antibodies in non-human serum
US8628727B2 (en) 2005-04-08 2014-01-14 Northwestern University Compositions, devices and methods for SERS and LSPR
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
CA2655079C (en) 2005-06-15 2013-12-10 University Of Maryland Biotechnology Institute Bioassays using plasmonic scattering from noble metal nanostructures
US20070092978A1 (en) 2005-10-20 2007-04-26 Ronald Mink Target ligand detection
JP5442179B2 (ja) 2005-10-21 2014-03-12 アルフレッサファーマ株式会社 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬
CN101365724A (zh) 2005-10-25 2009-02-11 路易斯安那科技大学研究基金会 包含多肽的多层膜、涂层和微粒
CN101360997B (zh) 2005-11-18 2013-05-01 美国政府健康及人类服务部，疾病控制和预防中心 改性心磷脂及其应用
US7790066B2 (en) 2006-03-03 2010-09-07 William Marsh Rice University Nanorice particles: hybrid plasmonic nanostructures
JP4810304B2 (ja) 2006-05-12 2011-11-09 キヤノン株式会社 化学センサ素子及びその製造方法
WO2007141581A1 (en) 2006-06-06 2007-12-13 Vivacta Ltd A method for sensing a chemical
JP2008157652A (ja) 2006-12-21 2008-07-10 Yokogawa Electric Corp 電源装置
US8426152B2 (en) 2007-01-03 2013-04-23 Lamdagen Corporation Enzymatic assay for LSPR
JP2009150708A (ja) 2007-12-19 2009-07-09 Canon Inc 標的物質の検出方法及び検査キット
EP2229251B1 (en) 2007-12-21 2013-03-20 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin A process for preparing nanoparticles
CN104327758A (zh) 2007-12-28 2015-02-04 3M创新有限公司 柔性封装膜系统
WO2009117510A2 (en) 2008-03-20 2009-09-24 Abaxis, Inc. Multi-wavelength analyses of sol-particle specific binding assays
WO2010006201A2 (en) 2008-07-10 2010-01-14 Abaxis, Inc. Methods of reducing non-specific interaction in metal nanoparticle assays
WO2010065781A2 (en) 2008-12-03 2010-06-10 Abaxis, Inc. Lateral flow strip assay with immobilized conjugate
US8313915B2 (en) 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
WO2010091293A1 (en) 2009-02-06 2010-08-12 The Regents Of The University Of California Plasmonic system for detecting binding of biological molecules
PL2401392T3 (pl) * 2009-02-27 2017-08-31 Beckman Coulter, Inc. Homogeniczne oznaczenia fazy roztworu
WO2010116345A1 (en) 2009-04-08 2010-10-14 National University Of Ireland, Galway Silver nanoplates
JP5563789B2 (ja) 2009-06-11 2014-07-30 富士フイルム株式会社 検出方法
CA2779191C (en) 2009-10-30 2018-01-30 Kyowa Medex Co., Ltd. Method and kit for measuring component to be assayed in specimen
EP2501719B1 (en) 2009-11-17 2015-11-04 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
KR101892182B1 (ko) 2009-11-20 2018-08-24 아박시스, 인크. 에를리키아 항체의 검출을 위한 펩티드, 장치 및 방법
WO2011065747A2 (ko) 2009-11-24 2011-06-03 한국생명공학연구원 나노입자를 이용한 미생물의 고속 검출방법
US9308582B2 (en) 2009-12-24 2016-04-12 Yi Sun Solution stable and chemically reactive metallic nanoparticles
EP2354792A1 (en) 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
AU2011248607B2 (en) 2010-04-27 2015-02-05 Ventana Medical Systems, Inc. Antibody-nanoparticle conjugates and methods for making and using such conjugates
KR20130095175A (ko) 2010-05-28 2013-08-27 고쿠리츠다이가쿠호진 토쿄고교 다이가꾸 금속 미립자 복합체 및 그 제조 방법
CN102023151B (zh) * 2010-09-17 2013-01-02 江南大学 用拉曼光谱在金纳米棒端面自组装介导下检测微囊藻毒素的方法
US9797842B2 (en) 2010-12-08 2017-10-24 Osaka Prefecture University Public Corporation Device and method utilizing a metallic nanoparticle assembly structure for detecting a target substance
JP5614278B2 (ja) 2010-12-24 2014-10-29 セイコーエプソン株式会社 センサーチップ、センサーチップの製造方法、検出装置
CN102103145B (zh) 2011-02-24 2013-01-16 南京基蛋生物科技有限公司 一种双放大系统的胶体金试纸条及其制备方法
US8697129B2 (en) 2011-03-02 2014-04-15 Imra America, Inc. Stable colloidal gold nanoparticles with controllable surface modification and functionalization
US8784895B2 (en) 2011-03-15 2014-07-22 Northwestern University Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same
JP5703098B2 (ja) 2011-03-31 2015-04-15 富士フイルム株式会社 生体分子検出装置および生体分子検出方法
CN102323422B (zh) * 2011-05-30 2014-03-12 中国科学院上海微系统与信息技术研究所 半定量同时检测cTnI和Myo的免疫层析试纸条及其制备
US20130230717A1 (en) 2011-09-02 2013-09-05 Washington University In St. Louis Copper nanostructures and methods for their preparation
US8758772B2 (en) 2011-11-04 2014-06-24 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
CH705758B1 (fr) 2011-11-15 2016-03-31 Metalor Technologies Int Nanoparticules cœur-coquille métal-silice, procédé de fabrication et dispositif de test par immunochromatographie comprenant de telles nanoparticules.
FI3489685T3 (fi) 2011-11-21 2023-12-21 Zoetis Services Llc Signaalin vahvistaminen lateraalivirtaus- ja vastaavissa immunomäärityksissä
US9823246B2 (en) 2011-12-28 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon
WO2013109832A1 (en) 2012-01-20 2013-07-25 Imra America, Inc. Stable colloidal suspensions of gold nanoconjugates and the method for preparing the same
EP2810067A4 (en) 2012-01-31 2015-12-09 American University Of Cairo Auc DIRECT DETECTION OF ILLEGAL BIOMARKERS IN CLINICAL SAMPLES USING CATIONIC NANOPARTICLE BASED ASSAYS AND VERSATILE AND GREEN METHODS FOR SYNTHESIS FROM ANISOTROPIC SILVER NANOSTRUCTURES
EP2625966A1 (en) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
TWI435843B (zh) 2012-04-27 2014-05-01 Univ Nat Taiwan 奈米顆粒的製造方法
TW201408690A (zh) 2012-05-05 2014-03-01 Academia Sinica 二氨基苯甲酸或鄰苯二胺共軛的胜肽作為功能性的醣類標幟劑
WO2014020293A1 (en) 2012-07-31 2014-02-06 Imperial Innovations Limited Assay
CN105051541B (zh) 2012-10-11 2017-07-04 爱贝斯股份有限公司 用于检测埃里希体属抗体的肽、装置和方法
AU2013329450B2 (en) 2012-10-11 2017-06-22 Coronado Aesthetics, Llc Silver nanoplate compositions and methods
US9441301B2 (en) 2012-12-06 2016-09-13 Nanyang Technological University Method for forming a bimetallic core-shell nanostructure
WO2014132833A1 (ja) 2013-03-01 2014-09-04 富士レビオ株式会社 未感作ラテックス試薬の劣化防止方法
MX362075B (es) 2013-03-14 2019-01-07 Abbott Lab Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo.
FR3003353B1 (fr) 2013-03-14 2015-03-06 Horiba Abx Sas Nouvelle methode de dosage en flux d'un objet d'interet
JP2016512241A (ja) * 2013-03-14 2016-04-25 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 改良された抗体検出のためのｈｃｖｎｓ３組換え抗原およびこの突然変異体
JP2014228385A (ja) 2013-05-22 2014-12-08 キヤノン株式会社 免疫試験方法および免疫試験キット
WO2014197222A1 (en) 2013-06-05 2014-12-11 Purdue Research Foundation Titanium nitride plasmonic nanoparticles for clinical therapeutic applications
CN103335984B (zh) * 2013-06-09 2015-10-28 清华大学 一种基于lspr的无实体壁微阵列芯片及其应用
EP3028043A4 (en) 2013-07-30 2017-04-19 Bio-rad Laboratories, Inc. Multiplex blocker beads for immunoassays
KR20160138059A (ko) 2014-02-26 2016-12-02 람다젠 코퍼레이션 향상된 검정 감도를 위한 디지털 lspr
WO2015160923A1 (en) 2014-04-15 2015-10-22 Rutgers, The State University Of New Jersey Gold nanostar substrates for sers sensing in the femtomolar regime
WO2016007942A1 (en) 2014-07-11 2016-01-14 Northwestern University Synthesis of uniform anisotropic nanoparticles
US20160202251A1 (en) 2014-08-01 2016-07-14 Beacle Inc. Virus-like particle for use in immunoassay, blocking agent for use in the immunoassay, and kit comprising the virus-like particle and the blocking agent
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
US11300519B2 (en) * 2015-02-19 2022-04-12 Ionica Sciences Reagents and methods for detecting infectious diseases
WO2016170183A1 (en) * 2015-04-24 2016-10-27 Pharmadiagnostics Nv Improved method of measuring an interaction between molecules
CA2991532C (en) 2015-08-04 2024-03-05 Abaxis, Inc. Signal amplification in solution-based plasmonic specific-binding partner assays
CN106290893B (zh) * 2016-07-18 2018-09-25 南昌大学 一种基于纳米铂探针检测牛乳β-乳球蛋白及其致敏性残基的方法
CN118275398A (zh) 2017-01-30 2024-07-02 硕腾服务有限责任公司 基于溶液的等离子体振子特异性结合配偶体测定和金属纳米结构

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110275061A1 (en) * 2007-03-20 2011-11-10 Kristin Weidemaier Assays using surface-enhanced raman spectroscopy (sers)-active particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEBRINA JANA ET AL, CAPPING AGENT-FREE GOLD NANOSTARS SHOW GREATLY INCREASED VERSATILITY AND SENSITIVITY FOR BIOSENSING, 27 February 2015 (2015-02-27) *
H.D. DHRUV, CONTROLLING NONSPECIFIC ADSORPTION OF PROTEINS AT BIO-INTERFACES FOR BIOSENSOR AND BIOMEDICAL APPLICATIONS, 31 December 2009 (2009-12-31) *

Also Published As

Publication number Publication date
KR102486615B1 (ko) 2023-01-11
KR20190112783A (ko) 2019-10-07
KR102654470B1 (ko) 2024-04-05
AU2022246447B2 (en) 2024-12-19
IL295118B1 (en) 2025-02-01
IL268238B (en) 2022-09-01
AU2018212009B2 (en) 2022-07-14
KR20240039224A (ko) 2024-03-26
MX2023012379A (es) 2023-11-01
KR20230011477A (ko) 2023-01-20
JP2023099008A (ja) 2023-07-11
US11977072B2 (en) 2024-05-07
EP3574308A4 (en) 2020-12-30
EP3574308A1 (en) 2019-12-04
NZ755886A (en) 2023-09-29
AU2018212009A1 (en) 2019-08-15
US20250044286A1 (en) 2025-02-06
CN118275398A (zh) 2024-07-02
KR102897521B1 (ko) 2025-12-09
US20220091113A1 (en) 2022-03-24
IL295118A (en) 2022-09-01
CN110892250A (zh) 2020-03-17
BR112019015664A2 (pt) 2020-03-31
JP7308148B2 (ja) 2023-07-13
IL268238A (en) 2019-09-26
MX2023002376A (es) 2023-03-23
JP2020509349A (ja) 2020-03-26
NZ796662A (en) 2026-03-27
AU2022246447A1 (en) 2022-11-03
CN120446063A (zh) 2025-08-08
MX2019008970A (es) 2019-12-19
WO2018140953A1 (en) 2018-08-02
CA3051465A1 (en) 2018-08-02

Similar Documents

Publication Publication Date Title
AU2022246447B2 (en) Solution-based plasmon specific-binding partner assays and metallic nanostructures
JP7818036B2 (ja) 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅
NZ755886B2 (en) Solution-based plasmon specific-binding partner assays and metallic nanostructures
HK40112807A (zh) 基於溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
HK40128797A (zh) 基於溶液的等离子体振子特异性结合配偶体测定和金属纳米结构
BR112019015664B1 (pt) Métodos de detecção de um analito alvo em uma amostra, mistura de reação e método para preparar um conjugado compreendendo um parceiro de ligação e uma nanoestrutura metálica