JP7114465B2 - 薬剤の細胞内送達のための化合物および組成物 - Google Patents

薬剤の細胞内送達のための化合物および組成物 Download PDF

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JP7114465B2
JP7114465B2 JP2018532573A JP2018532573A JP7114465B2 JP 7114465 B2 JP7114465 B2 JP 7114465B2 JP 2018532573 A JP2018532573 A JP 2018532573A JP 2018532573 A JP2018532573 A JP 2018532573A JP 7114465 B2 JP7114465 B2 JP 7114465B2
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JP2019508371A (ja
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イー． ベネナート、ケリー
ブッチャー、ウィリアム
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    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
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JP2018532573A 2015-12-22 2016-12-22 薬剤の細胞内送達のための化合物および組成物 Active JP7114465B2 (ja)

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US201562271200P 2015-12-22 2015-12-22
US201562271179P 2015-12-22 2015-12-22
US201562271137P 2015-12-22 2015-12-22
US201562271160P 2015-12-22 2015-12-22
US201562271146P 2015-12-22 2015-12-22
US62/271,137 2015-12-22
US62/271,200 2015-12-22
US62/271,160 2015-12-22
US62/271,146 2015-12-22
US62/271,179 2015-12-22
US201662338474P 2016-05-18 2016-05-18
US62/338,474 2016-05-18
US201662413345P 2016-10-26 2016-10-26
US62/413,345 2016-10-26
PCT/US2016/068300 WO2017112865A1 (en) 2015-12-22 2016-12-22 Compounds and compositions for intracellular delivery of agents

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