JP6993084B2 - １－（クロロメチル）－２，３－ジヒドロ－１ｈ－ベンゾ［ｅ］インドール二量体抗体 － 薬物コンジュゲート化合物、並びに使用及び処置の方法 - Google Patents

１－（クロロメチル）－２，３－ジヒドロ－１ｈ－ベンゾ［ｅ］インドール二量体抗体 － 薬物コンジュゲート化合物、並びに使用及び処置の方法 Download PDF

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JP6993084B2
JP6993084B2 JP2016533294A JP2016533294A JP6993084B2 JP 6993084 B2 JP6993084 B2 JP 6993084B2 JP 2016533294 A JP2016533294 A JP 2016533294A JP 2016533294 A JP2016533294 A JP 2016533294A JP 6993084 B2 JP6993084 B2 JP 6993084B2
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antibody
hvr
seq
amino acid
acid sequence
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JP2016530254A5 (enExample
JP2016530254A (ja
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ジョン エー． フライゲア，
トーマス エイチ． ピロー，
ブライアン サフィーナ，
ヴィシャル ヴァーマ，
ビンチン ウェイ，
ウィリアム デニー，
アンナ ギデンズ，
ホー リー，
クオ－リャン ルー，
クリスティアン ミラー，
ゴードン ルーキャッスル，
モアナ ターセル，
ミュリエル ボネット，
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Genentech Inc
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Genentech Inc
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JP2016533294A 2013-08-12 2014-06-16 １－（クロロメチル）－２，３－ジヒドロ－１ｈ－ベンゾ［ｅ］インドール二量体抗体 － 薬物コンジュゲート化合物、並びに使用及び処置の方法 Active JP6993084B2 (ja)

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US201361864889P 2013-08-12 2013-08-12
US61/864,889 2013-08-12
US201361916388P 2013-12-16 2013-12-16
US61/916,388 2013-12-16
US201461969499P 2014-03-24 2014-03-24
US61/969,499 2014-03-24
PCT/US2014/042560 WO2015023355A1 (en) 2013-08-12 2014-06-16 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment

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