KR20160042080A - 1-(클로로메틸)-2,3-디히드로-1H-벤조[e]인돌 이량체 항체-약물 접합체 화합물, 및 사용 및 치료 방법 - Google Patents

1-(클로로메틸)-2,3-디히드로-1H-벤조[e]인돌 이량체 항체-약물 접합체 화합물, 및 사용 및 치료 방법 Download PDF

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KR20160042080A
KR20160042080A KR1020167006280A KR20167006280A KR20160042080A KR 20160042080 A KR20160042080 A KR 20160042080A KR 1020167006280 A KR1020167006280 A KR 1020167006280A KR 20167006280 A KR20167006280 A KR 20167006280A KR 20160042080 A KR20160042080 A KR 20160042080A
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antibody
alkylene
hvr
seq
drug conjugate
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Korean (ko)
Inventor
존 에이. 플라이게어
토마스 에이치. 필로우
브라이언 사피나
비샬 베르마
빈칭 웨이
윌리엄 데니
안나 기든스
호 리
궈-량 루
크리스티안 밀러
고든 류캐슬
모아나 터셀
뮤리엘 보넷
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제넨테크, 인크.
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KR1020167006280A 2013-08-12 2014-06-16 1-(클로로메틸)-2,3-디히드로-1H-벤조[e]인돌 이량체 항체-약물 접합체 화합물, 및 사용 및 치료 방법 Withdrawn KR20160042080A (ko)

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US201361864889P 2013-08-12 2013-08-12
US61/864,889 2013-08-12
US201361916388P 2013-12-16 2013-12-16
US61/916,388 2013-12-16
US201461969499P 2014-03-24 2014-03-24
US61/969,499 2014-03-24
PCT/US2014/042560 WO2015023355A1 (en) 2013-08-12 2014-06-16 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment

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