JP6921846B6 - キナーゼ調節およびその適応症のための化合物および方法 - Google Patents

キナーゼ調節およびその適応症のための化合物および方法 Download PDF

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JP6921846B6
JP6921846B6 JP2018548829A JP2018548829A JP6921846B6 JP 6921846 B6 JP6921846 B6 JP 6921846B6 JP 2018548829 A JP2018548829 A JP 2018548829A JP 2018548829 A JP2018548829 A JP 2018548829A JP 6921846 B6 JP6921846 B6 JP 6921846B6
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cancer
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disease
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JP2019512505A5 (enExample
JP2019512505A (ja
JP6921846B2 (ja
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ジャック・リン
プラバ・エヌ・イブラヒム
アーロン・アルバース
ジョン・ビューエル
ズオジュン・グオ
フォンリー・ファム
ハンナ・パワーズ
ソンギュアン・シ
ウェイン・スピバック
グオシエン・ウー
ジアジョン・ジャン
イン・ジャン
ジェフリー・ウー
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Plexxikon Inc
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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JP2018548829A 2016-03-16 2017-03-15 キナーゼ調節およびその適応症のための化合物および方法 Active JP6921846B6 (ja)

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US201662309336P 2016-03-16 2016-03-16
US62/309,336 2016-03-16
PCT/US2017/022587 WO2017161045A1 (en) 2016-03-16 2017-03-15 Compounds and methods for kinase modulation and indications therefore

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JP2019512505A5 JP2019512505A5 (enExample) 2020-04-16
JP6921846B2 JP6921846B2 (ja) 2021-08-18
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US (1) US10160747B2 (enExample)
EP (1) EP3430005B1 (enExample)
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AU (1) AU2017232610B2 (enExample)
CA (1) CA3017972C (enExample)
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