JP6515122B2 - 一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 - Google Patents
一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 Download PDFInfo
- Publication number
- JP6515122B2 JP6515122B2 JP2017028200A JP2017028200A JP6515122B2 JP 6515122 B2 JP6515122 B2 JP 6515122B2 JP 2017028200 A JP2017028200 A JP 2017028200A JP 2017028200 A JP2017028200 A JP 2017028200A JP 6515122 B2 JP6515122 B2 JP 6515122B2
- Authority
- JP
- Japan
- Prior art keywords
- blood
- oxygen
- depleted
- plasma
- fibers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D19/00—Degasification of liquids
- B01D19/0031—Degasification of liquids by filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0213—Multiple bag systems for separating or storing blood components with isolated sections of the tube used as additive reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/26—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes and internal elements which are moving
- A61M1/262—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes and internal elements which are moving rotating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3403—Regulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/147—Microfiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0208—Oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0225—Carbon oxides, e.g. Carbon dioxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0415—Plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0429—Red blood cells; Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
Description
本願は、2011年8月10日に出願された米国特許仮出願第61/522,168号(発明の名称:Integrated Leukocyte, Oxygen and/or CO2 Depletion, and Plasma Separation Filter Device)及び2011年8月10日に出願された米国特許仮出願第61/522,157号(発明の名称:Leukoreduction and Oxygen Depletion Device)の優先主張出願であると共に2010年10月8日に出願された米国特許出願第12/910,350号(発明の名称:Blood Storage Bag System and Depletion Devices with Oxygen and Carbon Dioxide Depletion Capabilities)の一部継続出願(CIP)であり、この米国特許出願は、2010年5月5日に出願された米国特許仮出願第61/331,693号の権益主張出願であると共に2010年10月12日に出願された米国特許出願第12/903,057号(発明の名称:Oxygen Depletion Devices and Methods for Removing Oxygen from Red Blood Cells)のCIPであり、この米国特許出願は、2009年10月12日に出願された米国特許仮出願第61/250,661号及び2010年11月5日に出願された米国特許仮出願第61/410,684号の権益主張出願であり、これら米国特許出願及び米国特許仮出願を各々参照により引用し、その記載内容全体を本明細書の一部とする。
a.pRBCが長期間にわたって貯蔵されると、貯蔵中の劣化が累積してpRBCを劣化させ、それにより最大1%のpRBCを貯蔵中、溶血させると共に最高25%のpRBCが輸血直後に失われる。
b.生育不能pRBCは、慢性輸血患者に鉄過剰を生じさせる。
c.輸血は、組織灌流の増大の意図した結果を必ずしも達成しない。
・pRBC中のヘモグロビンは、2,3‐DPGが失われるので組織のところに酸素を効果的に放出しない。
・pRBCは、変形能が失われるので毛細血管床に入ってこれを灌流することができない。
長期間にわたって貯蔵されたpRBCを輸血すると、その結果として、「新鮮な」赤血球を輸血した場合と比較して、死亡率が高くなると共に入院期間が長くなる場合がある。
CaO + H2O -Ca(OH)2
水酸化カルシウムは、二酸化炭素と反応して炭酸カルシウムと水を生じ、次の通りである。
Ca(OH)2 + CO2- CaCO3 + H2O
次の理想気体の法則、即ち、
る。
図6A及び図6Bを参照すると、全血白血球減少フィルタ、O2及びCO2減損装置が部分断面図で示されている。全血又は供血者全血は、第1の入口410を通って装置内に流れ、そして分散され、その後減損媒体440を収容した内側チャンバ403内に流入する。
図7を参照すると、内側チャンバ403は、中空繊維490相互間に介在して設けられた減損媒体480を有する。血液は、中空繊維490を通って流れ、O2及びCO2が減損媒体480によって収着される。
図8A〜図8Dを参照すると、白血球/血小板/酸素/二酸化炭素減損装置1が示されている。抗凝固剤を含む全血か供血者全血かのいずれかが入口2を通って流入する。装置を通過した後、白血球/血小板/酸素/二酸化炭素減少赤血球濃縮物が出口3から出、そして収集袋内に集められる。図8Bは、回転シール組立体4を備えた一体型装置の断面を示している。入口2を通って装置に入った血液は、血液入口分布チャンバ7を通って白血球/血小板/酸素/二酸化炭素減損媒体8を有する内側チャンバ(血漿減損チャンバ10)に分布される。内側チャンバ(白血球/血小板/酸素/二酸化炭素減損チャンバ5)を回転させることにより、テイラーの渦が乱流を生じさせ、層流に起因して増大する拡散時間を減少させる。血漿を血液から分離することができるメンブレン(血漿フィルタ11)により血漿を濾過し、血漿を収集チャンバ12内に集めた後、血漿が、白血球/血小板/酸素/二酸化炭素減損血漿出口6を通って装置から出る。白血球/血小板/酸素/二酸化炭素減損血液は、出口分布チャンバ9に至り、そして出口3を通って流出する。
Claims (15)
- 血液を処理する方法であって、
容器に収容された血液を、血液フィルタ装置を通過させ、前記血液フィルタ装置は、
外壁、第1の入口、第1の出口及び第2の出口を備えたハウジングを含み、
血漿を血液から分離することができるメンブレンを含み、前記メンブレンは、前記ハウジング内に少なくとも1つの内側チャンバを形成し、前記血液は、前記第1の入口を通って前記血液フィルタ装置の前記少なくとも1つの内側チャンバに流入し、
前記少なくとも1つの内側チャンバ内に設けられた白血球及び酸素減損媒体を含み、前記白血球及び酸素減損媒体は、前記血液から白血球及び酸素を減損させることができ、 前記外壁と前記メンブレンとの間に設けられた外側チャンバを含み、
前記メンブレンに浸透させて前記血液から前記血漿を分離し、前記血液から減損した前記血漿は、前記外側チャンバに入り、そして前記第1の出口を経て前記ハウジングから出、
前記血液から、sO 2 が20%未満となるまで酸素を減損するとともに、白血球及び血漿を減損し、これにより酸素、白血球及び血漿が減損した前記血液は、濃縮赤血球(pRBC)として前記第2の出口を経て前記ハウジングから出、
前記白血球、酸素、及び血漿が減損した濃縮赤血球(pRBC)を、酸素収着剤、又は、酸素及び二酸化炭素収着剤を備える貯蔵容器に貯蔵する、方法。 - 前記方法は更に、CO2を前記血液から減損させ、前記減損媒体は又、CO2を前記血液から減損させることができる、請求項1記載の方法。
- 前記方法は更に、血小板を前記血液から減損させ、前記減損媒体は又、血小板を前記血液から減損させることができる、請求項1記載の方法。
- 前記方法は更に、前記少なくとも1つの内側チャンバを、前記外側チャンバに対して回転させる、請求項1記載の方法。
- 前記回転により、前記少なくとも1つの内側チャンバ内に渦が生じる、請求項4記載の方法。
- 前記白血球、酸素、及び血漿が減損した濃縮赤血球(pRBC)は、3%以下のO2飽和率を有する、請求項1記載の方法。
- 前記白血球、酸素、及び血漿が減損した濃縮赤血球(pRBC)は、30mmHg未満のpCO2を有する、請求項2記載の方法。
- 前記メンブレンは、親水性にしたPVDF、ナイロン、セルロースエステル、ポリスルホン、ポリエーテルスルホン、親水性にしたポリプロピレン及びポリアクリロニトリルから成る群から選択された少なくとも1つの材料で作られた少なくとも1枚のメンブレンである、請求項1記載の方法。
- 前記メンブレンの厚さは、25〜250ミクロンである、請求項1記載の方法。
- 前記メンブレンは、2ミクロン未満の孔径を有する、請求項1記載の方法。
- 前記白血球及び酸素減損媒体は、
生体適合性白血球結合表面化学組成で被覆された酸素収着材料と、
白血球減少材料であって、該白血球減少材料は、ポリオレフィン、ポリアミド、ポリエステル及び酸素スカベンジャと配合可能な他のポリマーから成る群から選択された少なくとも1つのポリマーであり、前記ポリマーは、形成され、次に繊維の状態に紡がれる、白血球減少材料と、
CO2収着材料であって、金属酸化物又は金属水酸化物であるCO2収着材料と、
を含むマクロ孔質構造体を有する、請求項1記載の方法。 - 前記マクロ孔質構造体は、
10〜30ミクロンの平均流量孔径、
表面積が少なくとも5×103cm2/グラムの媒体、又は
これらの組み合わせ
からなる群から選択された特徴を有する、請求項11記載の方法。 - 前記マクロ孔質構造体は、
(a)生体適合性白血球結合表面化学組成で被覆された微小球であって、前記微小球は、次に、白血球減少充填剤中に混入される、微小球、
(b)生体適合性白血球結合表面化学組成で被覆された微小球の層、
(c)1本又は2本以上の繊維、
(d)フィルタ構造体の状態に形成された1本又は2本以上の繊維、
からなる群から選択された構造を有する、請求項11記載の方法。 - 前記1本又は2本以上の繊維は、ポリ(エチレンメタクリレートシクロヘキセニルメチルアクリレート)、ポリオレフィン、ポリアミド、ポリエステル、エチレン/ビニルシクロヘキセンコポリマー(EVCH)及びこれらの組み合わせから成る群から選択された少なくとも1つの材料で作られている、請求項13記載の方法。
- 前記1本又は2本以上の繊維は、
(a)白血球減少繊維及び酸素収着繊維
(b)組み合わせ型白血球減少結合及び酸素減損繊維、
(c)CO2減損繊維、
(d)生体適合性白血球結合繊維で包囲された酸素収着繊維
(e)生体適合性白血球結合繊維で包囲された、酸素収着繊維及び二酸化炭素収着繊維
から成る群から選択された少なくとも1つの繊維を含む、請求項13記載の方法。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161522157P | 2011-08-10 | 2011-08-10 | |
US201161522168P | 2011-08-10 | 2011-08-10 | |
US61/522,157 | 2011-08-10 | ||
US61/522,168 | 2011-08-10 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014525177A Division JP6097293B2 (ja) | 2011-08-10 | 2012-08-10 | 一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2017094207A JP2017094207A (ja) | 2017-06-01 |
JP6515122B2 true JP6515122B2 (ja) | 2019-05-15 |
Family
ID=47668996
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014525177A Active JP6097293B2 (ja) | 2011-08-10 | 2012-08-10 | 一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 |
JP2017028200A Active JP6515122B2 (ja) | 2011-08-10 | 2017-02-17 | 一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014525177A Active JP6097293B2 (ja) | 2011-08-10 | 2012-08-10 | 一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 |
Country Status (8)
Country | Link |
---|---|
US (3) | US9005343B2 (ja) |
EP (4) | EP3533507B1 (ja) |
JP (2) | JP6097293B2 (ja) |
AU (2) | AU2012294269B2 (ja) |
CA (1) | CA2844449A1 (ja) |
ES (3) | ES2923571T3 (ja) |
PT (2) | PT3533507T (ja) |
WO (1) | WO2013023156A1 (ja) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9199016B2 (en) | 2009-10-12 | 2015-12-01 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
US11284616B2 (en) | 2010-05-05 | 2022-03-29 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
WO2012027582A1 (en) | 2010-08-25 | 2012-03-01 | New Health Sciences | Method for enhancing red blood cell quality and survival during storage |
PT2635114T (pt) | 2010-11-05 | 2020-06-16 | New Health Sciences Inc | Irradiação de glóbulos vermelhos e armazenamento anaeróbico |
US9067004B2 (en) | 2011-03-28 | 2015-06-30 | New Health Sciences, Inc. | Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly |
ES2923571T3 (es) * | 2011-08-10 | 2022-09-28 | Hemanext Inc | Dispositivo integrado de filtrado de leucocitos, oxígeno y/o CO2 y separación de plasma |
AU2014223165B2 (en) | 2013-02-28 | 2017-04-13 | Hemanext Inc. | Gas depletion and gas addition devices for blood treatment |
CN105120751B (zh) * | 2013-06-13 | 2018-03-13 | 皇家飞利浦有限公司 | 用于确定在感兴趣对象中的二氧化碳分压的设备和方法 |
US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
KR20180012242A (ko) | 2015-03-10 | 2018-02-05 | 뉴 헬스 사이언시즈 인코포레이티드 | 산소 감소 1회용 키트, 장치 및 이의 사용 방법 |
IL285359B2 (en) | 2015-04-23 | 2024-01-01 | Hemanext Inc | Anaerobic blood storage containers |
CA2985799A1 (en) | 2015-05-18 | 2016-11-24 | New Health Sciences, Inc. | Methods for the storage of whole blood, and compositions thereof |
ITUA20162865A1 (it) * | 2016-04-26 | 2017-10-26 | Istituto Scient Romagnolo Per Lo Studio E La Cura Dei Tumori I R S T S R L | Dispositivo e metodo per l’eliminazione di entità biologiche e/o chimiche indesiderate da fluidi biologici |
EP3463466B1 (en) | 2016-05-27 | 2022-02-16 | Hemanext Inc. | Anaerobic blood storage and pathogen inactivation method |
US20190136187A1 (en) * | 2016-06-26 | 2019-05-09 | National University Of Kaohsiung | Blood Isolation and Extraction Method and Device Thereof |
BR112019020220A2 (pt) * | 2017-06-06 | 2020-04-22 | Toray Industries | material para remoção de um complexo leucócito ativado-plaqueta ativada, e, coluna para purificação do sangue. |
US11298447B2 (en) | 2019-02-04 | 2022-04-12 | United States Of America As Represented By The Secretary Of The Air Force | Gasless extra-corporeal carbon dioxide removal |
RU2721494C1 (ru) * | 2019-06-14 | 2020-05-19 | Общество с ограниченной ответственностью "ЭСДИАР" | Устройство для сорбционной очистки биологических жидкостей |
CN115768501A (zh) | 2020-03-20 | 2023-03-07 | 荷兰商荷默克林有限公司 | 血液分离系统和血液制品 |
WO2021262147A1 (en) * | 2020-06-23 | 2021-12-30 | Qualigen Inc. | Devices and methods for on-line whole blood treatment |
Family Cites Families (312)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3064647A (en) | 1957-06-13 | 1962-11-20 | Baxter Laboratories Inc | Blood component separation method and apparatus |
US3361041A (en) | 1964-01-13 | 1968-01-02 | Equitable Paper Bag Co | Method and apparatus for making gusseted header bags |
FR1455087A (fr) | 1964-05-08 | 1966-04-01 | Schwarz Biores | Procédé de conservation du sang |
US3942529A (en) | 1967-02-01 | 1976-03-09 | Investrop A.G. | Package and method for storing blood |
US3668837A (en) | 1970-02-13 | 1972-06-13 | Pall Corp | Separator of the semipermeable membrane type |
US3668838A (en) | 1970-12-07 | 1972-06-13 | Dalph C Mcneil | Flash economizer |
US3803810A (en) | 1972-05-01 | 1974-04-16 | Pall Corp | Liquid-gas separator and filter |
US3910841A (en) | 1974-04-02 | 1975-10-07 | William G Esmond | Stacked exchange device |
US4131200A (en) | 1976-07-06 | 1978-12-26 | Union Carbide Corporation | Thermoplastic blood bag |
US4082509A (en) | 1976-08-05 | 1978-04-04 | Dow Corning Corporation | Method of storing blood and a blood storage bag therefor |
US4086924A (en) | 1976-10-06 | 1978-05-02 | Haemonetics Corporation | Plasmapheresis apparatus |
SE421999B (sv) | 1977-10-17 | 1982-02-15 | Gambro Dialysatoren | Anordning for diffusion och/eller filtration av emnen mellan tva fluider via semipermeabla membran vilken anordning innefattar parallellkopplade banor innehallande seriekopplade kamrar |
US4370160A (en) | 1978-06-27 | 1983-01-25 | Dow Corning Corporation | Process for preparing silicone microparticles |
US6150085A (en) | 1998-09-16 | 2000-11-21 | The United States Of America As Represented By The Secretary Of The Army | Prolonged storage of red blood cells and composition |
US6447987B1 (en) | 1978-09-09 | 2002-09-10 | The United States Of America As Represented By The Secretary Of The Army | Prolonged storage of red blood cells |
GB2035093B (en) | 1978-10-26 | 1983-01-12 | Baxter Travenol Lab | Medical articles made of blood compatible polymers |
US4222379A (en) | 1978-10-26 | 1980-09-16 | Baxter Travenol Laboratories, Inc. | Multiple blood bag having plasticizer-free portions and a high blood component survival rate |
US4228032A (en) | 1978-11-06 | 1980-10-14 | Dow Corning Corporation | Method of storing blood and a blood storage bag therefore |
US4342723A (en) | 1978-11-24 | 1982-08-03 | Shin-Etsu Polymer Co., Ltd. | Gas-exchange sheet members |
US4256692A (en) | 1979-02-01 | 1981-03-17 | C. R. Bard, Inc. | Membrane oxygenator |
US4253458A (en) | 1979-03-08 | 1981-03-03 | Baxter Travenol Laboratories, Inc. | Method and apparatus for collecting blood plasma |
US4262581A (en) | 1979-05-04 | 1981-04-21 | Kcl Corporation | Method and apparatus for making printed gusset bags |
GB2078171B (en) | 1979-11-02 | 1984-05-02 | Toyo Boseki | Multi-layered vessel and process for producing same |
US4381775A (en) | 1980-02-05 | 1983-05-03 | Takeda Chemical Industries, Ltd. | Method for low pressure filtration of plasma from blood |
US4267269A (en) | 1980-02-05 | 1981-05-12 | Baxter Travenol Laboratories, Inc. | Red cell storage solution |
CA1156641A (en) | 1980-03-17 | 1983-11-08 | Takanari Nawata | Oxygen and carbon dioxide absorbent and process for storing coffee by using the same |
US4314480A (en) | 1980-07-14 | 1982-02-09 | Baxter Travenol Laboratories, Inc. | Venous pressure isolator |
US5382526A (en) | 1980-10-31 | 1995-01-17 | Baxter International Inc. | Blood storage container and material |
US4440815A (en) | 1981-06-29 | 1984-04-03 | Abbott Laboratories | Clear, autoclavable plastic formulation for medical liquid containers |
US4455299A (en) | 1981-11-20 | 1984-06-19 | Baxter Travenol Laboratories, Inc. | Storage of blood platelets |
US4386069A (en) | 1981-12-02 | 1983-05-31 | Baxter Travenol Laboratories, Inc. | Additive solution and method for preserving normal red cell morphology in whole blood during storage |
FI82832C (fi) | 1982-04-27 | 1991-04-25 | Wellcome Found | Foerfarande foer framstaellning av terapeutiskt anvaendbara disubstituerade xanten- och xantonderivat. |
ZA832943B (en) | 1982-04-27 | 1984-12-24 | Wellcome Found | Tricyclic compounds,preparation use and intermediates |
US5310674A (en) | 1982-05-10 | 1994-05-10 | Bar-Ilan University | Apertured cell carrier |
JPS58194879U (ja) | 1982-06-17 | 1983-12-24 | 三菱電機株式会社 | 電子ビ−ム溶接機 |
DE3225408A1 (de) | 1982-07-07 | 1984-01-12 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten |
BE898469A (fr) | 1982-12-20 | 1984-03-30 | El Paso Polyolefins | Compositions polyoléfiniques stérilisables à la chaleur et articles fabriqués à partir de ces compositions. |
US4670013A (en) | 1982-12-27 | 1987-06-02 | Miles Laboratories, Inc. | Container for blood and blood components |
KR890005278B1 (ko) | 1983-01-28 | 1989-12-20 | 미쓰비시가스가가꾸 가부시끼 가이샤 | 탈산소제 포장체 |
US4540416A (en) | 1983-08-18 | 1985-09-10 | El Paso Polyolefins Company | Heat-sterilizable polyolefin compositions and articles manufactured therefrom |
US4859360A (en) | 1983-10-27 | 1989-08-22 | Biosynergy, Inc. | Cholesteric liquid crystal formulations and time/temperature monitoring means |
US4701267B1 (en) | 1984-03-15 | 1996-03-12 | Asahi Medical Co | Method for removing leukocytes |
US5417986A (en) | 1984-03-16 | 1995-05-23 | The United States Of America As Represented By The Secretary Of The Army | Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres |
US4831012A (en) | 1984-03-23 | 1989-05-16 | Baxter International Inc. | Purified hemoglobin solutions and method for making same |
EP0168755B1 (en) | 1984-07-16 | 1991-04-17 | Sumitomo Bakelite Company Limited | Container and method for storing blood |
US4585735A (en) | 1984-07-19 | 1986-04-29 | American National Red Cross | Prolonged storage of red blood cells |
US4654053A (en) | 1984-07-27 | 1987-03-31 | University Patents, Inc. | Oxygen sorbent |
US4629544A (en) | 1984-09-24 | 1986-12-16 | Aquanautics Corporation | Apparatus and method for reversibly removing ligands from carriers |
US4568328A (en) | 1984-10-29 | 1986-02-04 | Extracorporeal Medical Specialties, Inc. | Automated photophoresis blood portion control methods and apparatus |
US4748121A (en) | 1984-11-30 | 1988-05-31 | Ppg Industries, Inc. | Porous glass fibers with immobilized biochemically active material |
US4713176A (en) | 1985-04-12 | 1987-12-15 | Hemascience Laboratories, Inc. | Plasmapheresis system and method |
FR2581289A1 (fr) | 1985-05-06 | 1986-11-07 | Rgl Transfusion Sanguine Centr | Solution synthetique pour la conservation prolongee de concentres erythrocytaires |
KR890002855B1 (ko) | 1985-06-26 | 1989-08-05 | 미쯔비시 가스 가가구 가부시기가이샤 | 시이트상 탈산소제 및 그 제조방법 |
SE448444B (sv) | 1985-07-08 | 1987-02-23 | Alfa Laval Food & Dairy Eng | Forslutbar pase samt anvendning av denna |
IT1218450B (it) | 1985-09-24 | 1990-04-19 | Teresa Borgione | Perfezionamenti agli ossigenatori per il sangue, a fibre cave |
US4961928A (en) | 1986-03-19 | 1990-10-09 | American Red Cross | Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets |
JPS62157385U (ja) | 1986-03-26 | 1987-10-06 | ||
US4769318A (en) | 1986-06-03 | 1988-09-06 | Ube Industries, Ltd. | Additive solution for blood preservation and activation |
JPS6363616A (ja) | 1986-09-04 | 1988-03-22 | Showa Denko Kk | 赤血球濃厚液の保存剤及び保存方法 |
JPH0326882Y2 (ja) | 1986-12-12 | 1991-06-11 | ||
US4880786A (en) | 1987-01-14 | 1989-11-14 | Ube Industries, Ltd. | Additive solution for blood preservation and activation |
US5000848A (en) | 1987-01-28 | 1991-03-19 | Membrex, Inc. | Rotary filtration device with hyperphilic membrane |
JP2700170B2 (ja) | 1987-07-11 | 1998-01-19 | 大日本インキ化学工業株式会社 | 膜型人工肺 |
DE3722984A1 (de) | 1987-07-11 | 1989-01-19 | Biotest Pharma Gmbh | Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten |
US5192320A (en) | 1987-07-11 | 1993-03-09 | Dainippon Ink And Chemicals Inc. | Artificial lung and method of using it |
JPH07121340B2 (ja) | 1987-07-11 | 1995-12-25 | 大日本インキ化学工業株式会社 | 中空繊維膜 |
CA1323271C (en) | 1987-07-11 | 1993-10-19 | Takanori Anazawa | Membrane-type artificial lung and method of using it |
US4925572A (en) | 1987-10-20 | 1990-05-15 | Pall Corporation | Device and method for depletion of the leukocyte content of blood and blood components |
US4861867A (en) | 1988-02-03 | 1989-08-29 | Baxter International, Inc. | Purified hemoglobin solutions and method for making same |
US4880548A (en) | 1988-02-17 | 1989-11-14 | Pall Corporation | Device and method for separating leucocytes from platelet concentrate |
JP2685544B2 (ja) | 1988-11-11 | 1997-12-03 | 株式会社日立製作所 | 血液フィルタおよび血液検査方法並びに血液検査装置 |
US4998990A (en) | 1988-12-20 | 1991-03-12 | The Coca-Cola Company | Collapsible bag with evacuation passageway and method for making the same |
US5229012A (en) | 1989-05-09 | 1993-07-20 | Pall Corporation | Method for depletion of the leucocyte content of blood and blood components |
US5120659A (en) | 1989-06-26 | 1992-06-09 | Mine Safety Appliances Company | Deuterated water test method |
DE69016129T2 (de) | 1989-08-18 | 1995-05-24 | Akzo Nobel Nv | Vakzin gegen Escherichia coli. |
US5152905A (en) | 1989-09-12 | 1992-10-06 | Pall Corporation | Method for processing blood for human transfusion |
US5037419A (en) | 1989-09-21 | 1991-08-06 | Eastman Kodak Company | Blood bag system containing vitamin E |
IL95912A (en) | 1989-10-06 | 1998-08-16 | American Nat Red Cross | A method for extending the shelf life of blood cells |
US5386014A (en) | 1989-11-22 | 1995-01-31 | Enzon, Inc. | Chemically modified hemoglobin as an effective, stable, non-immunogenic red blood cell substitute |
US5139668A (en) | 1989-12-27 | 1992-08-18 | Alberta Research Corporation | Hollow fiber bundle element |
SU1718766A1 (ru) | 1990-01-30 | 1992-03-15 | Ленинградский научно-исследовательский институт гематологии и переливания крови | Способ консервировани эритроцитов крови |
JP2888590B2 (ja) | 1990-03-30 | 1999-05-10 | テルモ株式会社 | 血漿および濃厚赤血球採取用器具 |
US6187572B1 (en) | 1990-04-16 | 2001-02-13 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants |
CA2040993C (en) | 1990-04-25 | 2001-08-07 | Yoshiaki Inoue | Oxygen absorbent composition and method of preserving article with same |
US6077659A (en) | 1990-05-15 | 2000-06-20 | New York Blood Center, Inc. | Vitamin E and derivatives thereof prevent potassium ion leakage and other types of damage in red cells that are virus sterilized by phthalocyanines and light |
US5194158A (en) | 1990-06-15 | 1993-03-16 | Matson Stephen L | Radon removal system and process |
JP2953753B2 (ja) | 1990-06-28 | 1999-09-27 | テルモ株式会社 | 血漿採取装置 |
JPH0474515A (ja) | 1990-07-13 | 1992-03-09 | Toray Ind Inc | 酸素吸収体 |
US5368808A (en) | 1990-10-26 | 1994-11-29 | Kyoraku Co., Ltd. | Blowbag manufacturing method |
EP0509083B1 (en) | 1990-11-07 | 1997-07-16 | Baxter International Inc. | Red blood cell storage solution |
US5208335A (en) | 1991-03-19 | 1993-05-04 | Air Products And Chemicals, Inc. | Reversible oxygen sorbent compositions |
US5789152A (en) | 1991-04-30 | 1998-08-04 | Basil T. Hone | Composition and method for detecting HIV with baculovirus derived vesicles |
JP2811371B2 (ja) | 1991-06-21 | 1998-10-15 | バクスター、インターナショナル、インコーポレイテッド | 体液中の病原を不活性化する方法 |
US5443743A (en) | 1991-09-11 | 1995-08-22 | Pall Corporation | Gas plasma treated porous medium and method of separation using same |
US5353793A (en) | 1991-11-25 | 1994-10-11 | Oishi-Kogyo Company | Sensor apparatus |
JP3461360B2 (ja) | 1991-11-30 | 2003-10-27 | 旭メディカル株式会社 | 白血球除去用フィルター材料 |
JP3337232B2 (ja) | 1991-12-26 | 2002-10-21 | 東レ・ダウコーニング・シリコーン株式会社 | シリコーン硬化物微粒子と無機質微粒子からなる粉体混合物の製造方法 |
US5356375A (en) | 1992-04-06 | 1994-10-18 | Namic U.S.A. Corporation | Positive pressure fluid delivery and waste removal system |
JP3177713B2 (ja) | 1992-04-30 | 2001-06-18 | 科学技術振興事業団 | 輸血用血液または血液製剤の保存方法 |
US5304487A (en) | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
JPH05317413A (ja) * | 1992-05-20 | 1993-12-03 | Asahi Medical Co Ltd | 白血球除去血液成分採取装置 |
US6248690B1 (en) | 1992-05-26 | 2001-06-19 | Multisorb Technologies, Inc. | Oxygen absorber |
US5529821A (en) | 1992-06-29 | 1996-06-25 | Terumo Kabushiki Kaisha | Container for storing blood or blood component |
DE4229325C2 (de) | 1992-09-02 | 1995-12-21 | Heraeus Instr Gmbh | Kulturgefäß für Zellkulturen |
US5328268A (en) | 1992-10-30 | 1994-07-12 | Custom Packaging Systems, Inc. | Bulk bag with restrainer |
SE9301581D0 (sv) | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Protein formulation |
US5427663A (en) | 1993-06-08 | 1995-06-27 | British Technology Group Usa Inc. | Microlithographic array for macromolecule and cell fractionation |
US5744056A (en) | 1993-07-16 | 1998-04-28 | Amoco Corporation | Oxygen-scavenging compositions and articles |
US5362442A (en) | 1993-07-22 | 1994-11-08 | 2920913 Canada Inc. | Method for sterilizing products with gamma radiation |
IT1260685B (it) | 1993-09-29 | 1996-04-22 | Sorin Biomedica Spa | Dispositivo per il contenimento di sangue |
GB2283015B (en) | 1993-10-22 | 1998-05-13 | Chemitreat Pte Ltd | Membrane reactor for the removal of dissolved oxygen from water |
US20010037978A1 (en) * | 1999-04-20 | 2001-11-08 | Daryl R. Calhoun | Filter assembly having a flexible housing and method of making same |
CA2143365A1 (en) | 1994-03-14 | 1995-09-15 | Hugh V. Cottingham | Nucleic acid amplification method and apparatus |
ES2128055T3 (es) | 1994-04-20 | 1999-05-01 | Us Army | Vacuna contra infecciones de bacterias gram-negativas. |
US5617873A (en) | 1994-08-25 | 1997-04-08 | The United States Of America As Represented By The Administrator, Of The National Aeronautics And Space Administration | Non-invasive method and apparatus for monitoring intracranial pressure and pressure volume index in humans |
US6156231A (en) | 1994-09-08 | 2000-12-05 | Multisorb Technologies, Inc. | Oxygen absorbing composition with cover layer |
US5476764A (en) | 1994-09-16 | 1995-12-19 | The Regents Of The University Of California | Method using CO for extending the useful shelf-life of refrigerated red blood cells |
US6045701A (en) | 1994-10-17 | 2000-04-04 | Baxter International Inc. | Method of filtering a fluid suspension with a membrane having a particular coating |
DE4446270C1 (de) | 1994-12-23 | 1996-02-29 | Hewlett Packard Gmbh | Basisstruktur für einen Flüssigkeitschromatographie-Entgaser |
US5730989A (en) | 1995-02-16 | 1998-03-24 | Novavax, Inc. | Oral vaccine against gram negative bacterial infection |
US5605934A (en) | 1995-03-23 | 1997-02-25 | Baxter International Inc. | Method of manufacturing and storing solutions |
US6288027B1 (en) | 1995-03-23 | 2001-09-11 | Biopure Corporation | Preserving a hemoglobin blood substitute with a transparent overwrap |
US6610832B1 (en) | 1995-03-23 | 2003-08-26 | Biopure Corporation | Preserving a hemoglobin blood substitute with a transparent overwrap |
US5691452A (en) | 1995-03-23 | 1997-11-25 | Biopure Corporation | Method for preserving a hemoglobin blood substitute |
EP1093720B1 (en) | 1995-03-23 | 2009-11-04 | Biopure Corporation | Stable polymerized hemoglobin blood-substitute |
US5895810A (en) | 1995-03-23 | 1999-04-20 | Biopure Corporation | Stable polymerized hemoglobin and use thereof |
WO1996029864A1 (en) | 1995-03-24 | 1996-10-03 | Organ, Inc. | Rejuvenating outdated red cells |
WO1996032178A1 (en) | 1995-04-13 | 1996-10-17 | Travenol Laboratories (Israel) Ltd. | Leukocyte filtration method and apparatus |
US5624794A (en) | 1995-06-05 | 1997-04-29 | The Regents Of The University Of California | Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas |
US5716852A (en) | 1996-03-29 | 1998-02-10 | University Of Washington | Microfabricated diffusion-based chemical sensor |
US5762791A (en) | 1995-08-09 | 1998-06-09 | Baxter International Inc. | Systems for separating high hematocrit red blood cell concentrations |
US6527957B1 (en) * | 1995-08-09 | 2003-03-04 | Baxter International Inc. | Methods for separating, collecting and storing red blood cells |
US5709472A (en) | 1995-10-23 | 1998-01-20 | Lifelines Technology, Inc. | Time-temperature indicator device and method of manufacture |
US6042264A (en) | 1995-10-23 | 2000-03-28 | Lifelines Technology, Inc. | Time-temperature indicator device and method of manufacture |
WO1997015380A1 (en) | 1995-10-23 | 1997-05-01 | Hemasure, Inc. | Extra-lumenal crossflow plasmapheresis devices |
US5686304A (en) | 1995-12-15 | 1997-11-11 | Avecor Cardiovascular, Inc. | Cell culture apparatus and method |
US5693230A (en) | 1996-01-25 | 1997-12-02 | Gas Research Institute | Hollow fiber contactor and process |
US5863460A (en) | 1996-04-01 | 1999-01-26 | Chiron Diagnostics Corporation | Oxygen sensing membranes and methods of making same |
US5698250A (en) | 1996-04-03 | 1997-12-16 | Tenneco Packaging Inc. | Modifield atmosphere package for cut of raw meat |
SE9601348D0 (sv) | 1996-04-10 | 1996-04-10 | Pharmacia Ab | Improved containers for parenteral fluids |
US5906285A (en) | 1996-05-10 | 1999-05-25 | Plastipak Packaging, Inc. | Plastic blow molded container |
IT1285393B1 (it) | 1996-06-04 | 1998-06-03 | Hospal Dasco Spa | Formulazione di polivinile cloruro plastificato per la realizzazione di componenti in materiale biocompatibile, in particolare di linee |
EP0904844A4 (en) | 1996-06-10 | 2005-08-31 | Nippon Telegraph & Telephone | BIFLUIDAL ADJUSTMENT AND DEVICE USING SAID ADJUSTMENT TO FREEZE AND DRY BIOLOGICAL SUBSTANCES CONTAINING A LIQUID |
US6808675B1 (en) | 1996-06-25 | 2004-10-26 | Thermogenesis Corp. | Freezing and thawing bag, mold, apparatus and method |
DE69728983T2 (de) * | 1996-07-09 | 2005-04-07 | Pall Corp. | Filtervorrichtung für biologische Fluide mit einem Leukocyten abreichernden Medium |
US6254628B1 (en) | 1996-12-09 | 2001-07-03 | Micro Therapeutics, Inc. | Intracranial stent |
US5876604A (en) | 1996-10-24 | 1999-03-02 | Compact Membrane Systems, Inc | Method of gasifying or degasifying a liquid |
US6358678B1 (en) | 1998-02-11 | 2002-03-19 | The United States Of America As Represented By The Secretary Of The Navy | Applications of reversible crosslinking and co-treatment in stabilization and viral inactivations of erythrocytes |
WO1998041279A1 (en) | 1997-03-17 | 1998-09-24 | Nims, Inc. | Physiologic signs feedback system |
US6482585B2 (en) | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
US6403124B1 (en) | 1997-04-16 | 2002-06-11 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
US6162396A (en) * | 1997-04-26 | 2000-12-19 | The Regents Of The University Of California | Blood storage device and method for oxygen removal |
US6164821A (en) | 1997-05-09 | 2000-12-26 | The Procter & Gamble Company | Flexible, self-supporting storage bag with hinged, framed closure |
US5789151A (en) | 1997-05-15 | 1998-08-04 | The Regents Of The University Of California | Prolonged cold storage of red blood cells by oxygen removal and additive usage |
WO1998052629A2 (en) | 1997-05-20 | 1998-11-26 | Zymequest, Inc. | Cell processing systems |
IT1293309B1 (it) | 1997-07-09 | 1999-02-16 | Sis Ter Spa | Apparecchiatura per il trattamento del sangue con dispositivo di scambio a membrana |
US6368871B1 (en) | 1997-08-13 | 2002-04-09 | Cepheid | Non-planar microstructures for manipulation of fluid samples |
US6022477A (en) | 1997-11-14 | 2000-02-08 | New Jersey Institute Of Technology | Method and apparatus for isolation purification of biomolecules |
JP3758853B2 (ja) * | 1997-11-28 | 2006-03-22 | テルモ株式会社 | 白血球除去器 |
DE19754573A1 (de) | 1997-12-09 | 1999-06-10 | Bayer Ag | Pharmazeutische Zusammensetzung zur Behandlung von Schlaganfall und Schädel-Hirn-Trauma |
BR9909074A (pt) | 1998-03-25 | 2000-12-05 | Chevron Phillips Chemical Co | Composição e camada apropriada para remover oxigênio, artigo de fabricação apropriado como um recipiente, pelìcula de múltiplas camadas, artigo para embalagem, processo para fabricar um material polimérico, composição de polìmero removedor de oxigênio não odoroso, e, recipiente rìgido para alimentos ou bebidas |
US6027623A (en) | 1998-04-22 | 2000-02-22 | Toyo Technologies, Inc. | Device and method for electrophoretic fraction |
US5937617A (en) | 1998-05-01 | 1999-08-17 | Innoflex Incorporated | Pouch with pre-inserted straw |
US6090062A (en) | 1998-05-29 | 2000-07-18 | Wayne State University | Programmable antisiphon shunt system |
US6908553B1 (en) * | 1998-07-08 | 2005-06-21 | Baxter International Inc. | Composite membrane with particulate matter substantially immobilized therein |
US20030215784A1 (en) | 1998-07-21 | 2003-11-20 | Dumont Larry Joe | Method and apparatus for inactivation of biological contaminants using photosensitizers |
US20070099170A1 (en) | 1998-07-21 | 2007-05-03 | Navigant Biotechnologies, Inc. | Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate |
AU764287B2 (en) | 1998-08-31 | 2003-08-14 | Walter Reed Army Institute Of Research | Prolonged storage of red blood cells |
JP4638986B2 (ja) | 1998-10-16 | 2011-02-23 | テルモ メディカル コーポレイション | 血液処理装置 |
AUPP676898A0 (en) | 1998-10-26 | 1998-11-19 | Noble House Group Pty Ltd | Sampling first in blood collection |
US6413713B1 (en) | 1998-10-30 | 2002-07-02 | Hyperbaric Systems | Method for preserving blood platelets |
CA2287768C (en) | 1998-11-02 | 2004-01-13 | Ahmed Abdoh | Method for automated data collection, analysis and reporting |
AU2975500A (en) | 1999-01-27 | 2001-08-07 | Government of the United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA), The | Ultrasonic apparatus and technique to measure changes in intracranial pressure |
US6582496B1 (en) | 2000-01-28 | 2003-06-24 | Mykrolis Corporation | Hollow fiber membrane contactor |
US6337026B1 (en) | 1999-03-08 | 2002-01-08 | Whatman Hemasure, Inc. | Leukocyte reduction filtration media |
US6945411B1 (en) | 1999-03-16 | 2005-09-20 | Pall Corporation | Biological fluid filter and system |
US6097293A (en) | 1999-04-15 | 2000-08-01 | Industrial Technology, Inc. | Passive electrical marker for underground use and method of making thereof |
US6210601B1 (en) | 1999-04-21 | 2001-04-03 | Larry A. Hottle | Method of making an oxygen scavenging sealant composition |
DE60017900T2 (de) | 1999-04-30 | 2006-04-06 | Massachusetts General Hospital, Boston | Herstellung von dreidimensionalem vaskularisierten gewebe mittels der verwendung von zweidimensionalen mikrohergestellten formen |
US6387461B1 (en) | 1999-05-06 | 2002-05-14 | Cryovac, Inc. | Oxygen scavenger compositions |
US6629919B2 (en) | 1999-06-03 | 2003-10-07 | Haemonetics Corporation | Core for blood processing apparatus |
US6610772B1 (en) | 1999-08-10 | 2003-08-26 | Eastman Chemical Company | Platelet particle polymer composite with oxygen scavenging organic cations |
US6287284B1 (en) | 1999-09-27 | 2001-09-11 | Npt, Inc. | Silicone bag assembly |
MXPA01008017A (es) | 1999-12-08 | 2002-04-24 | Baxter Int | Membrana microporosa para filtro, metodo para fabricar una membrana microporosa para filtro y separador que emplea membranas microporosas para filtro. |
US6315815B1 (en) | 1999-12-16 | 2001-11-13 | United Technologies Corporation | Membrane based fuel deoxygenator |
WO2001066237A1 (de) | 2000-03-07 | 2001-09-13 | Mat Adsorption Technologies Gmbh & Co. Kg | Modul mit membranelementen in cross-flow und in dead-end anordnung |
WO2001074158A2 (en) | 2000-03-31 | 2001-10-11 | Baxter International Inc. | Systems and methods for collecting leukocyte-reduced blood components, including plasma that is free or virtually free of cellular blood species |
US6468732B1 (en) | 2000-04-04 | 2002-10-22 | Bayer Corporation | Method and long-term stable bicarbonate-containing diluent composition, and storage means therefor, for reducing or reversing aeration induced cell shrinkage and storage induced cell swelling of a whole blood sample |
ES2257315T3 (es) | 2000-04-21 | 2006-08-01 | Kuraray Co., Ltd. | Tubo multicapa y dispositivo medico que comprende el tubo multicapa. |
US6402818B1 (en) | 2000-06-02 | 2002-06-11 | Celgard Inc. | Degassing a liquid with a membrane contactor |
US6558571B1 (en) | 2000-08-11 | 2003-05-06 | Multisorb Technologies, Inc. | Oxygen-absorbing composition and method |
AU2001286628A1 (en) | 2000-08-24 | 2002-03-04 | Veritas Medicine, Inc. | Recruiting a patient into a clinical trial |
JP2002087971A (ja) * | 2000-09-07 | 2002-03-27 | Asahi Medical Co Ltd | 生体組織再生用細胞の分離方法及び装置 |
EP1328312A4 (en) | 2000-09-27 | 2007-08-01 | Cobe Cardiovascular Inc | blood perfusion system |
US7208120B2 (en) | 2000-09-27 | 2007-04-24 | The Trustees Of Boston University | Cellular diagnostic arrays, methods of using and processing for producing same |
US20080027368A1 (en) | 2000-09-27 | 2008-01-31 | Sorin Group Usa, Inc. | Disposable cartridge for a blood perfusion system |
US6692443B2 (en) | 2000-09-29 | 2004-02-17 | New Health Sciences, Inc. | Systems and methods for investigating blood flow |
US7604599B2 (en) | 2000-09-29 | 2009-10-20 | New Health Sciences, Inc. | Systems and methods for using dynamic vascular assessment to improve vascular stent placement, application, design and marketing |
US7104958B2 (en) | 2001-10-01 | 2006-09-12 | New Health Sciences, Inc. | Systems and methods for investigating intracranial pressure |
US6955648B2 (en) | 2000-09-29 | 2005-10-18 | New Health Sciences, Inc. | Precision brain blood flow assessment remotely in real time using nanotechnology ultrasound |
US6494909B2 (en) | 2000-12-01 | 2002-12-17 | Prodesco, Inc. | Endovascular valve |
US6770434B2 (en) | 2000-12-29 | 2004-08-03 | The Provost, Fellows And Scholars Of The College Of The Holy & Undivided Trinity Of Queen Elizabeth Near Dublin | Biological assay method |
WO2002053193A2 (en) | 2001-01-02 | 2002-07-11 | The Charles Stark Draper Laboratory, Inc. | Tissue engineering of three-dimensional vascularized using microfabricated polymer assembly technology |
US6773670B2 (en) | 2001-02-09 | 2004-08-10 | Cardiovention, Inc. C/O The Brenner Group, Inc. | Blood filter having a sensor for active gas removal and methods of use |
JP2002253936A (ja) | 2001-02-28 | 2002-09-10 | Japan Gore Tex Inc | 分離膜チューブ及び分離膜モジュール |
US6613280B2 (en) | 2001-03-20 | 2003-09-02 | Therox, Inc. | Disposable cartridge for producing gas-enriched fluids |
US6974447B2 (en) | 2001-04-17 | 2005-12-13 | Baxter International Inc. | High gas barrier receptacle and closure assembly |
CN2502700Y (zh) | 2001-05-10 | 2002-07-31 | 张明礼 | 血液收集装置 |
US6697667B1 (en) | 2001-05-31 | 2004-02-24 | Advanced Cardiovascular Systems, Inc. | Apparatus and method for locating coronary sinus |
ATE425995T1 (de) | 2001-07-31 | 2009-04-15 | Asahi Kasei Medical Co Ltd | Leukozytenfilter mit polymerbeschichtung |
US7909788B2 (en) | 2001-08-01 | 2011-03-22 | Battelle Memorial Institute | Carbon dioxide removal from whole blood by photolytic activation |
US6682698B2 (en) | 2001-08-23 | 2004-01-27 | Michigan Critical Care Consultants, Inc. | Apparatus for exchanging gases in a liquid |
DE10151343A1 (de) | 2001-10-22 | 2003-05-08 | Vita 34 Ag | Beutelsystem für die Kryokonservierung von Körperflüssigkeiten |
CA2467087A1 (en) | 2001-11-16 | 2003-05-30 | Hemanext, Llc | Additive solution for blood preservation |
CA2467223A1 (en) | 2001-11-16 | 2003-05-30 | Hollinger Digital, Inc. | Method for extending the useful shelf-life of refrigerated red blood cells by nutrient supplementation |
EP2208502B1 (en) | 2001-12-10 | 2019-05-08 | Terumo BCT, Inc. | Disposable assembly for an apheresis system |
US20050210141A1 (en) | 2002-01-31 | 2005-09-22 | Telefonaktiebolaget Lm Ericsson (Publ) | Method for providing multiple sdp media flows in a single pop context |
US6761695B2 (en) | 2002-03-07 | 2004-07-13 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Method and apparatus for non-invasive measurement of changes in intracranial pressure |
EP1487559A4 (en) | 2002-03-14 | 2008-12-24 | Fenwal Inc | DEVICE FOR EXTRACTING COMPOUNDS |
JP4498748B2 (ja) | 2002-03-19 | 2010-07-07 | インテグリス・インコーポレーテッド | 中空糸膜接触装置およびプロセス |
US20030183801A1 (en) | 2002-03-28 | 2003-10-02 | Hu Yang | Porous oxygen scavenging material |
US6773407B2 (en) | 2002-04-08 | 2004-08-10 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Non-invasive method of determining absolute intracranial pressure |
US20030190272A1 (en) | 2002-04-08 | 2003-10-09 | Dennis Raine | Sterilization containers and methods for radiation sterilization of liquid products |
US6767466B2 (en) * | 2002-04-08 | 2004-07-27 | Teva Medical Ltd. | Leukocyte filter construction |
DE60322600D1 (de) * | 2002-04-16 | 2008-09-11 | Gambro Bct Inc | System zum Auftrennen von Blutkomponenten, Gerät und Verfahren |
CA2482021C (en) | 2002-04-24 | 2007-06-19 | Gambro, Inc. | Removal of adenine during a process of pathogen reducing blood and blood components |
US20040126880A1 (en) | 2002-06-07 | 2004-07-01 | Manders Ernest K. | Sterilization, stabilization and preservation of functional biologics |
US6899743B2 (en) | 2002-06-12 | 2005-05-31 | Membrane Technology And Research, Inc. | Separation of organic mixtures using gas separation or pervaporation and dephlegmation |
US6878335B2 (en) | 2002-06-21 | 2005-04-12 | Vital Signs, Inc. | Process of manufacturing a breathing bag and breathing bag manufactured by such process |
US6817979B2 (en) | 2002-06-28 | 2004-11-16 | Nokia Corporation | System and method for interacting with a user's virtual physiological model via a mobile terminal |
JP2004089495A (ja) | 2002-08-30 | 2004-03-25 | Terumo Corp | バッグ連結体 |
US20080160107A1 (en) | 2002-09-10 | 2008-07-03 | Nitric Biotherapeutics, Inc. | Use of nitric oxide gas to treat blood and blood products |
WO2004043381A2 (en) | 2002-11-08 | 2004-05-27 | The Brigham And Women's Hospital, Inc. | Compositions and methods for prolonging survival of platelets |
US6899822B2 (en) | 2002-11-18 | 2005-05-31 | Multisorb Technologies, Inc. | Oxygen-absorbing composition |
DE10327988B4 (de) | 2002-12-18 | 2009-05-14 | Alpha Plan Gmbh | Filtermodul zur Aufbereitung von Flüssigkeiten |
ITTO20030039A1 (it) | 2003-01-24 | 2004-07-25 | Fresenius Hemocare Italia Srl | Filtro per separare leucociti da sangue intero e/o da preparati derivati dal sangue, procedimento per la fabbricazione del filtro, dispositivo e utilizzazione. |
US7517453B2 (en) | 2003-03-01 | 2009-04-14 | The Trustees Of Boston University | Microvascular network device |
US8828226B2 (en) | 2003-03-01 | 2014-09-09 | The Trustees Of Boston University | System for assessing the efficacy of stored red blood cells using microvascular networks |
US6709492B1 (en) | 2003-04-04 | 2004-03-23 | United Technologies Corporation | Planar membrane deoxygenator |
US20040254560A1 (en) | 2003-06-11 | 2004-12-16 | Coelho Philip H. | Rupture resistant blow molded freezer bag for containing blood products |
US7754798B2 (en) | 2003-08-28 | 2010-07-13 | Cryovac, Inc. | Oxygen scavenger block copolymers and compositions |
US7078100B2 (en) | 2003-08-28 | 2006-07-18 | Cryovac, Inc. | Oxygen scavenger compositions derived from isophthalic acid and/or terephthalic acid monomer or derivatives thereof |
US8070952B2 (en) | 2003-10-03 | 2011-12-06 | Medical Service S.R.L. | Apparatus and method for the treatment of blood |
US7097690B2 (en) | 2003-10-10 | 2006-08-29 | Scimed Life Systems, Inc. | Apparatus and method for removing gasses from a liquid |
US20050085785A1 (en) | 2003-10-17 | 2005-04-21 | Sherwin Shang | High impact strength film and non-pvc containing container and pouch and overpouch |
CA2544612C (en) | 2003-11-24 | 2011-12-20 | Gambro Lundia Ab | Degassing device and end-cap assembly for a filter including such a degassing device |
US20050137517A1 (en) * | 2003-12-19 | 2005-06-23 | Baxter International Inc. | Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation |
US7347887B2 (en) | 2003-12-22 | 2008-03-25 | The Boc Group, Inc. | Oxygen sorbent compositions and methods of using same |
WO2005066042A2 (en) * | 2003-12-24 | 2005-07-21 | Cryovac, Inc. | Oxygen scavenger compositions |
US7125498B2 (en) | 2004-02-04 | 2006-10-24 | Multisorb Technologies, Inc. | Oxygen-absorbing compositions and method |
US9314014B2 (en) | 2004-02-18 | 2016-04-19 | University Of Maryland, Baltimore | Compositions and methods for the storage of red blood cells |
JP4579569B2 (ja) | 2004-04-16 | 2010-11-10 | 株式会社クレハ | 多層二軸延伸ブローボトル及びその製造方法 |
WO2006031385A2 (en) | 2004-08-24 | 2006-03-23 | The General Hospital Corporation | Particle separating devices, systems and methods |
US20060081524A1 (en) | 2004-10-15 | 2006-04-20 | Amitava Sengupta | Membrane contactor and method of making the same |
KR100721054B1 (ko) | 2004-11-23 | 2007-05-25 | 주식회사 뉴하트바이오 | 혈액정화 및/또는 혈액산화용 필터모듈, 그를 이용한혈액정화 및 혈액산화 방법 그리고 그를 포함하는혈액정화 장치 |
AU2005322136B2 (en) | 2004-12-23 | 2011-01-06 | Hospira, Inc. | Port closure system for intravenous fluid container |
US20100221697A1 (en) | 2005-01-12 | 2010-09-02 | BioVec Transfusions, LLC | Composition for preserving platelets and method of using and storing the same |
EP1683579A1 (fr) * | 2005-01-25 | 2006-07-26 | Jean-Denis Rochat | Dispositif jetable pour la séparation en continu par centrifugation d'un liquide physiologique |
US7465335B2 (en) | 2005-02-02 | 2008-12-16 | United Technologies Corporation | Fuel deoxygenation system with textured oxygen permeable membrane |
BRPI0520102A2 (pt) | 2005-02-17 | 2009-04-22 | Univ Cincinnati | composiÇço aquosa para armazenagem de hemÁcias suspensço de hemÁcias, mÉtodo de preservaÇço de hemÁcias ou glàbulos vermelhos do sangue ("red blood cells" - rbc`s) durante um perÍodo de armazenagem, mÉtodo para aperfeiÇoamento da manutenÇço de membrana de hemÁcias ou glàbulos vermelhos do sangue ("red blood cells" - rbc) e supressço de apoptose de rbc`s durante um perÍodo de armazenagem, mÉtodo para reduÇço de fragilidade de hemÁcias (rbc`s) e supressço de hemàlise de rbc`s durante um perÍodo de armazenagem, mÉtodo para aumentar a viabilidade de hemÁcias (rbc`s), mÉtodo de preservaÇço de hamÁcias (rbc`s) durante um perÍodo de armazenagem, combinaÇço, e composiÇço aquosa |
JP3772909B1 (ja) | 2005-04-04 | 2006-05-10 | 東洋紡績株式会社 | 血液浄化器 |
US20060226087A1 (en) | 2005-04-08 | 2006-10-12 | Mission Medical, Inc. | Method and apparatus for blood separations |
CN2780207Y (zh) | 2005-04-12 | 2006-05-17 | 浙江科锐生物科技有限公司 | 一次性使用的活性炭血液灌流器 |
EP1879599B1 (en) | 2005-04-20 | 2013-10-16 | Fred Hutchinson Cancer Research Center | Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms |
JP4584018B2 (ja) | 2005-05-09 | 2010-11-17 | 日東電工株式会社 | 脱気装置 |
US7465336B2 (en) | 2005-06-09 | 2008-12-16 | United Technologies Corporation | Fuel deoxygenation system with non-planar plate members |
CN2894710Y (zh) | 2006-03-31 | 2007-05-02 | 天津市海河医院 | 医用血气交换器 |
US7763097B2 (en) | 2006-06-08 | 2010-07-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Devices, systems and methods for reducing the concentration of a chemical entity in fluids |
US7571903B2 (en) | 2006-08-18 | 2009-08-11 | Goss International Americas, Inc. | Mobile hopper system |
US7517146B2 (en) | 2006-08-30 | 2009-04-14 | Temptime Corporation | Color-retaining excess-temperature exposure indicator |
EP1902740A1 (en) | 2006-09-19 | 2008-03-26 | Maco Pharma S.A. | Blood bag system and process for the inactivation of pathogens in platelet concentrates by use of the blood bag system |
US7713614B2 (en) | 2006-09-19 | 2010-05-11 | Kuraray Co., Ltd. | Resin composition and multilayer structure |
BRPI0717293A2 (pt) | 2006-09-25 | 2013-10-15 | Nipro Corp | Recipiente de plástico moldado a sopro para infusão |
US20080098894A1 (en) | 2006-11-01 | 2008-05-01 | Sabatino Daniel R | Acoustic degassing heat exchanger |
WO2008089337A1 (en) | 2007-01-19 | 2008-07-24 | The Regents Of The University Of Michigan | Compositions and methods for preserving red blood cells |
JP2008253452A (ja) | 2007-04-03 | 2008-10-23 | Sekisui Chem Co Ltd | 真空採血管 |
US8398743B2 (en) | 2007-05-08 | 2013-03-19 | General Electric Company | Methods and systems for reducing carbon dioxide in combustion flue gases |
KR101071402B1 (ko) | 2007-09-11 | 2011-10-07 | (주) 비에이치케이 | 혈액 정화장치 |
EP2252362A1 (en) | 2008-02-07 | 2010-11-24 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Intracorporeal gas exchange devices, systems and methods |
EP2274083A1 (en) | 2008-04-30 | 2011-01-19 | Gambro Lundia AB | Hydrophobic deaeration membrane |
EP2113266A1 (en) | 2008-04-30 | 2009-11-04 | Gambro Lundia AB | Degassing device |
JP5560459B2 (ja) | 2008-10-17 | 2014-07-30 | 三菱マテリアル株式会社 | 金属ナノ粒子の合成方法 |
US8177884B2 (en) | 2009-05-20 | 2012-05-15 | United Technologies Corporation | Fuel deoxygenator with porous support plate |
US8377172B2 (en) * | 2009-06-11 | 2013-02-19 | Georgia Tech Research Corporation | Fiber sorbents |
CA2772320A1 (en) | 2009-07-31 | 2011-02-03 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Removal of oxygen from biological fluids |
CN102574322B (zh) | 2009-08-04 | 2014-06-25 | 三菱瓦斯化学株式会社 | 容器的制造方法 |
WO2011046963A1 (en) | 2009-10-12 | 2011-04-21 | New Health Sciences, Inc. | Oxygen depletion devices and methods for removing oxygen from red blood cells |
BR112012008683B8 (pt) * | 2009-10-12 | 2022-11-08 | Hemanext Inc | dispositivo de armazenagem de sangue para armazenar sangue depletado de oxigênio e dióxido de carbono, dispositivo de depleção de oxigênio e dióxido de carbono, método para remover oxigênio e dióxido de carbono de hemácias, sistema de armazenagem de sangue, dispositivo de armazenagem de sangue, método para remover oxigênio de hemácias e método para aumentar os níveis de adenosina trifosfato (atp) nas hemácias |
US9199016B2 (en) | 2009-10-12 | 2015-12-01 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
JP2011092905A (ja) | 2009-10-30 | 2011-05-12 | Japan Gore Tex Inc | 脱気膜の製造方法、封筒状物、および該封筒状物を用いた脱気装置 |
WO2011068897A1 (en) | 2009-12-01 | 2011-06-09 | Exthera Medical, Llc | Method for removing cytokines from blood with surface immobilized polysaccharides |
WO2011091074A2 (en) | 2010-01-19 | 2011-07-28 | The Cleveland Clinic Foundation | Nanoporous membranes, devices, and methods for respiratory gas exchange |
WO2012027582A1 (en) | 2010-08-25 | 2012-03-01 | New Health Sciences | Method for enhancing red blood cell quality and survival during storage |
PT2635114T (pt) | 2010-11-05 | 2020-06-16 | New Health Sciences Inc | Irradiação de glóbulos vermelhos e armazenamento anaeróbico |
US20120219633A1 (en) | 2011-02-28 | 2012-08-30 | Pall Corporation | Removal of immunoglobulins and leukocytes from biological fluids |
CN103429214B (zh) | 2011-03-09 | 2015-09-30 | 泰尔茂株式会社 | 氧运输体给予系统、氧运输体氧合装置及氧运输体用收容体 |
CN103492041B (zh) | 2011-03-28 | 2017-02-08 | 新健康科学股份有限公司 | 用于在红细胞血液处理过程中使用惰性载气和歧管组件去除氧和二氧化碳的方法和系统 |
US9067004B2 (en) | 2011-03-28 | 2015-06-30 | New Health Sciences, Inc. | Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly |
EP4190154A1 (en) | 2011-07-05 | 2023-06-07 | Hemanext Inc. | A system for extended storage of red blood cells |
ES2923571T3 (es) * | 2011-08-10 | 2022-09-28 | Hemanext Inc | Dispositivo integrado de filtrado de leucocitos, oxígeno y/o CO2 y separación de plasma |
EP2836956B1 (en) | 2012-04-13 | 2019-06-26 | OLogN Technologies AG | Secure zone for digital communications |
EP2852461B1 (en) | 2012-05-22 | 2022-06-15 | Hemanext Inc. | Capillary network devices and methods of use |
US9083010B2 (en) | 2012-07-18 | 2015-07-14 | Nthdegree Technologies Worldwide Inc. | Diatomaceous energy storage devices |
US9057901B2 (en) | 2012-11-29 | 2015-06-16 | Shenzhen China Star Optoelectronics Technology Co., Ltd | Plastic frame, backlight module and liquid crystal display device |
US20140158604A1 (en) | 2012-12-12 | 2014-06-12 | Jacques Chammas | Platelet Storage Container |
AU2014223165B2 (en) | 2013-02-28 | 2017-04-13 | Hemanext Inc. | Gas depletion and gas addition devices for blood treatment |
US20140248005A1 (en) | 2013-03-01 | 2014-09-04 | Stokely-Van Camp, Inc. | Stand-Up Pouch |
US9174771B2 (en) | 2013-03-15 | 2015-11-03 | Sangart, Inc. | Packaging system for preserving a nonoxygenated hemoglobin based oxygen therapeutic product |
WO2014194931A1 (en) | 2013-06-03 | 2014-12-11 | Onderzoeks- En Ontwikkelingsfonds Rode Kruis-Vlaanderen | Pathogen reduction treatment |
EP3706298A1 (en) | 2014-03-05 | 2020-09-09 | LG Innotek Co., Ltd. | Lens driving device and camera module comprising same |
KR20180012242A (ko) | 2015-03-10 | 2018-02-05 | 뉴 헬스 사이언시즈 인코포레이티드 | 산소 감소 1회용 키트, 장치 및 이의 사용 방법 |
IL285359B2 (en) | 2015-04-23 | 2024-01-01 | Hemanext Inc | Anaerobic blood storage containers |
-
2012
- 2012-08-10 ES ES19163305T patent/ES2923571T3/es active Active
- 2012-08-10 CA CA2844449A patent/CA2844449A1/en not_active Abandoned
- 2012-08-10 WO PCT/US2012/050380 patent/WO2013023156A1/en unknown
- 2012-08-10 EP EP19163305.6A patent/EP3533507B1/en active Active
- 2012-08-10 ES ES12822387.2T patent/ES2576977T3/es active Active
- 2012-08-10 US US13/572,412 patent/US9005343B2/en active Active
- 2012-08-10 ES ES16154118T patent/ES2742949T3/es active Active
- 2012-08-10 PT PT191633056T patent/PT3533507T/pt unknown
- 2012-08-10 AU AU2012294269A patent/AU2012294269B2/en active Active
- 2012-08-10 PT PT16154118T patent/PT3061509T/pt unknown
- 2012-08-10 EP EP16154118.0A patent/EP3061509B1/en active Active
- 2012-08-10 EP EP22165200.1A patent/EP4074395B1/en active Active
- 2012-08-10 EP EP12822387.2A patent/EP2741834B1/en active Active
- 2012-08-10 JP JP2014525177A patent/JP6097293B2/ja active Active
-
2015
- 2015-03-02 US US14/635,560 patent/US9539375B2/en active Active
-
2016
- 2016-10-31 AU AU2016253545A patent/AU2016253545B2/en active Active
- 2016-11-29 US US15/363,687 patent/US10065134B2/en active Active
-
2017
- 2017-02-17 JP JP2017028200A patent/JP6515122B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
US10065134B2 (en) | 2018-09-04 |
US9005343B2 (en) | 2015-04-14 |
EP2741834B1 (en) | 2016-05-04 |
EP3061509B1 (en) | 2019-05-22 |
EP4074395A2 (en) | 2022-10-19 |
AU2012294269B2 (en) | 2016-11-24 |
EP3061509A1 (en) | 2016-08-31 |
US9539375B2 (en) | 2017-01-10 |
JP6097293B2 (ja) | 2017-03-15 |
US20150165102A1 (en) | 2015-06-18 |
EP2741834A1 (en) | 2014-06-18 |
EP3533507B1 (en) | 2022-03-30 |
JP2014527436A (ja) | 2014-10-16 |
EP3533507A1 (en) | 2019-09-04 |
EP2741834A4 (en) | 2015-02-18 |
WO2013023156A1 (en) | 2013-02-14 |
PT3533507T (pt) | 2022-07-25 |
EP4074395A3 (en) | 2022-11-23 |
EP4074395B1 (en) | 2024-01-24 |
AU2016253545A1 (en) | 2016-11-17 |
PT3061509T (pt) | 2019-09-10 |
US20130047861A1 (en) | 2013-02-28 |
US20170072339A1 (en) | 2017-03-16 |
CA2844449A1 (en) | 2013-02-14 |
AU2016253545B2 (en) | 2018-07-05 |
AU2012294269A1 (en) | 2014-03-06 |
ES2742949T3 (es) | 2020-02-17 |
ES2923571T3 (es) | 2022-09-28 |
JP2017094207A (ja) | 2017-06-01 |
ES2576977T3 (es) | 2016-07-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6515122B2 (ja) | 一体型の白血球、酸素及び/又は二酸化炭素減損・血漿分離フィルタ装置 | |
JP6796664B2 (ja) | 血液処理のためのガス枯渇化およびガス添加デバイス | |
CN107530377B (zh) | 氧减少一次性套件、装置及其使用方法 | |
US20230173147A1 (en) | Blood separation system and blood products |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20180111 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180117 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180416 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180618 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A132 Effective date: 20181119 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20190218 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190311 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190325 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20190415 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6515122 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |