JP6016260B2 - 自動注射装置に関する改良 - Google Patents
自動注射装置に関する改良 Download PDFInfo
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- JP6016260B2 JP6016260B2 JP2012108830A JP2012108830A JP6016260B2 JP 6016260 B2 JP6016260 B2 JP 6016260B2 JP 2012108830 A JP2012108830 A JP 2012108830A JP 2012108830 A JP2012108830 A JP 2012108830A JP 6016260 B2 JP6016260 B2 JP 6016260B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
本発明は自動注射装置に関する。
種々の形態の自動注射装置が存在し、操作によって注射器の針は前方へ移動し、注射器の作動前に保護ハウジングから突出して針から所定投与量の液体を発射する。液体が加圧発射される前に、注射器が確実に前方へ移動し針を露出させ、実際の注射が行われる前に針から滴下が発生しないようにすることが重要である。
本発明の課題は、このような所望方法で作動する機構を提供することにある。
本発明によれば、注射装置のハウジング内の注射器の一端の針から所定投与量の液体を発射するための注射装置が提供され、前記注射器はプランジャにより移動可能であり、前記プランジャは、前記ハウジングの一端の作動付勢部材の解放後に、針がハウジングにより覆われる第一位置から針がハウジングの他端から突出する第二位置へ前記注射器を移動させ、前記プランジャは、作動付勢部材の解放前には前記注射器の他端から延びた長手中央に位置決めされた可撓性突出部を有するロッドの形態であり、前記プランジャの第一移動が作動付勢部材の付勢下で可撓性突出部を注射器の他端に対して付勢して、注射器が第一位置から第二位置へ移動するようにし、それにより注射器の更なる移動を抑制し、結果として可撓突出性部が内方へ崩壊し注射器へ侵入し、そのようにしてプランジャを第二移動により注射器内で移動させて栓に接触し作用して注射器内の液体を圧縮しかつ注射器の針へ液体を発現させる。
上述の構成により、前記可撓性突出部は、かかる突出部を内方へ崩壊させ前記プランジャを注射器内へ移動させて液体を注射器から発射させる程度の力が加わるまで、第一位置から第二位置へ注射器を移動せるために、その突出位置を維持する。
前記可撓性突出部は前記ロッドの通常の周辺から突出するが、その周辺内へ圧縮可能である一つまたはそれ以上の肘部を含んでよい。二つの前記肘部は前記ロッドの長手スリットの両側で形成されていてよい。前記肘部は、前記ロッドの上中実部と下中実部との間の長手スリットの両側に、一対のアームとして予め形成されていてよい。
好適には、前記注射装置は、前記作動付勢部材が解放されるまで前記ハウジング内に注射器を後退維持するために、前記注射器のハウジングと前記注射器の他端との間に作用する復帰付勢部材を含む。
前記ハウジング内に設けられた一つまたはそれ以上の前記付勢部材はコイルバネの形態であってよい。
本発明は種々の方法で実行されてよく、かつ次に好適形態を添付図面を参照して説明する。
図面に示された注射装置は、保護ハウジング２内に設置された注射器１を含む。注射器１は栓（bung)４により所定位置に保持される液体投与量を収容し、かつ栓４へ圧力を加えることにより投与量を発射する針５を具備した容器３を含む。前記３は拡大頭部６を有する。プランジャ７はコイルバネ８により前方へ付勢されるが、１１で概略的に示されたトリガが作動してプランジャ７およびコイルバネ８を解放するときにまで、係止位置（図１）に後退保持される。使用前に、注射器１はコイルバネ９によりハウジング２内に引っ込んでいる。
理解されるように、プランジャ７は一対の突出肘部１０を形成する中央部を有するロッドの形態である。突出肘部１０は成形プランジャ７の一部として予備形成される。突出肘部１０は可撓性であり、内方へ移動可能であり、ロッドの一部の周辺をロッドの残部の類似の周辺に適合させる。図２から理解されるように、プランジャ７が解放されかつバネ８により付勢されるときに、肘部１０により形成された拡大領域は３の拡大頭部６に当接し、かつ加えられる力は、拡大頭部６がハウジング２の上部に当接するまで、バネ９を圧縮するに十分であり、それにより３の移動が抑制される。肘部１０が３の内部へ侵入するときに、バネ８により生じる連続的付勢により肘部１０は内方へ圧縮される。崩壊状態の肘部１０によりプランジャ７は３内で容易に移動でき、栓４に作用して注射器の内容物を針５から発射させる。
プランジャ７の図示形態は、幾つかの技術的利点を提供する。プランジャ７の図示形態は一体成形できる。同様に、突出肘部の崩壊運動は、適宜発射力を提供して針を皮膚の適宜深さまで侵入させるが、注射器の容器の内壁に対する空気抵抗は比較的小さく、その一撃の残部に対するバネの推進力の大部分が栓４へ付与されるようにする。理解されるように、崩壊突出部の他の形態が崩壊肘部に代わって使用できる。
１ 注射器
２ ハウジング
３ 容器
４ 栓
５ 針
６ 拡大頭部
７ プランジャ
１０ 肘部
２ ハウジング
３ 容器
４ 栓
５ 針
６ 拡大頭部
７ プランジャ
１０ 肘部
Claims (5)
- ハウジング、
前記ハウジングに対して被覆される後退位置と、前記ハウジングに対して突出する発射位置との間を移動するために、前記ハウジング内に摺動自在に取り付けられた注射器、
前記注射器に摺動自在に取り付けられ、かつ前記注射器の先端に設けられた針を通って液体を前記注射器から排出するために、摺動可能に取り付けられた栓、
上中実部、前記栓を移動させかつ前記栓に排出力を伝達する働きをする先端を有する下中実部、および前記上中実部と前記下中実部との間で中心軸に沿って延在する長手スリットの両側に設けられた二つの可撓性肘部を有する崩壊可能に突出する領域を含むプランジャ、
前記ハウジングに対して被覆される後退位置から突出する発射位置へ、前記注射器を駆動するために、前記プランジャを移動させる働きをする作動付勢コイルスプリング、ならびに
前記作動付勢コイルスプリングが解放されるまで、前記ハウジングに対して被覆される後退位置に前記注射器を保持するために、前記ハウジングと前記注射器の近位端との間で作用する復帰付勢部材を含み、
前記作動付勢コイルスプリングが解放されると、前記崩壊可能に突出する領域は、前記注射器へ侵入する前に第一の膨張位置になり、前記注射器の前記近位端に静止し、
かつ、前記作動付勢コイルスプリングにより生じる連続的付勢のもとで、前記崩壊可能に突出する領域は、前記注射器内で第二の圧縮位置において、前記注射器に侵入するように前記長手方向のスリットに向けて内方に崩壊し、こうして前記栓に排出力を付与して前記注射器から液体投与量を排出するために、前記崩壊可能に突出する領域は、前記プランジャを注射器内において前進させることを可能とする、自動注射装置。 - 前記プランジャの崩壊可能に突出する領域は、前記ハウジングに対して被覆される後退位置から、前記ハウジングに対して突出する発射位置へ、前記注射器を駆動して、前記針が前記ハウジングから突出するように構成されている、請求項１に記載の自動注射装置。
- 前記復帰付勢部材は、コイルバネの形態である、請求項１に記載の自動注射装置。
- 前記ハウジングは、前記注射器が、前記ハウジングに対して被覆される後退位置と突出する発射位置との間を移動するときに、使用者の身体の注射部位に固定される、請求項１の自動注射装置。
- 前記プランジャは一体成形されている、請求項１に記載の自動注射装置。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0414054.7 | 2004-06-23 | ||
| GB0414054A GB0414054D0 (en) | 2004-06-23 | 2004-06-23 | Improvements relating to automatic injection devices |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007517459A Division JP2008503296A (ja) | 2004-06-23 | 2005-06-23 | 自動注射装置に関する改良 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016136734A Division JP2016179256A (ja) | 2004-06-23 | 2016-07-11 | 自動注射装置に関する改良 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012143646A JP2012143646A (ja) | 2012-08-02 |
| JP6016260B2 true JP6016260B2 (ja) | 2016-10-26 |
Family
ID=32800025
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007517459A Pending JP2008503296A (ja) | 2004-06-23 | 2005-06-23 | 自動注射装置に関する改良 |
| JP2011196424A Withdrawn JP2011240202A (ja) | 2004-06-23 | 2011-09-08 | 自動注射装置に関する改良 |
| JP2012108830A Expired - Fee Related JP6016260B2 (ja) | 2004-06-23 | 2012-05-10 | 自動注射装置に関する改良 |
| JP2014077283A Expired - Fee Related JP5883057B2 (ja) | 2004-06-23 | 2014-04-03 | 自動注射装置に関する改良 |
| JP2016136734A Pending JP2016179256A (ja) | 2004-06-23 | 2016-07-11 | 自動注射装置に関する改良 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007517459A Pending JP2008503296A (ja) | 2004-06-23 | 2005-06-23 | 自動注射装置に関する改良 |
| JP2011196424A Withdrawn JP2011240202A (ja) | 2004-06-23 | 2011-09-08 | 自動注射装置に関する改良 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014077283A Expired - Fee Related JP5883057B2 (ja) | 2004-06-23 | 2014-04-03 | 自動注射装置に関する改良 |
| JP2016136734A Pending JP2016179256A (ja) | 2004-06-23 | 2016-07-11 | 自動注射装置に関する改良 |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US7938802B2 (ja) |
| EP (3) | EP1758627B1 (ja) |
| JP (5) | JP2008503296A (ja) |
| KR (2) | KR101202123B1 (ja) |
| CN (4) | CN103083763B (ja) |
| AU (1) | AU2005256832B2 (ja) |
| BR (1) | BRPI0512554B1 (ja) |
| CA (2) | CA2571571C (ja) |
| ES (1) | ES2672336T3 (ja) |
| GB (1) | GB0414054D0 (ja) |
| HK (1) | HK1184738A1 (ja) |
| IN (1) | IN2014DN04769A (ja) |
| MX (2) | MXPA06015056A (ja) |
| NZ (3) | NZ552340A (ja) |
| RU (1) | RU2387460C2 (ja) |
| WO (1) | WO2006000785A1 (ja) |
| ZA (1) | ZA200700289B (ja) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003209095A1 (en) | 2002-02-11 | 2003-09-04 | Antares Pharma, Inc. | Intradermal injector |
| US20090204076A1 (en) * | 2003-02-03 | 2009-08-13 | Barry Peter Liversidge | Medical Injector |
| GB0414054D0 (en) * | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| US11590286B2 (en) | 2004-11-22 | 2023-02-28 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
| US7648483B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| US10737028B2 (en) | 2004-11-22 | 2020-08-11 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
| US7947017B2 (en) | 2004-11-22 | 2011-05-24 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| GB2453069B (en) | 2004-11-22 | 2009-12-09 | Intelliject Llc | Devices,systems and methods for medicament delivery |
| DK1850892T4 (da) | 2005-01-24 | 2023-06-06 | Antares Pharma Inc | Forfyldt nål-assisteret sprøjtejetinjektor |
| US8231573B2 (en) | 2005-02-01 | 2012-07-31 | Intelliject, Inc. | Medicament delivery device having an electronic circuit system |
| US9022980B2 (en) | 2005-02-01 | 2015-05-05 | Kaleo, Inc. | Medical injector simulation device |
| US8361026B2 (en) | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
| US8206360B2 (en) | 2005-02-01 | 2012-06-26 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| AU2006210865B2 (en) | 2005-02-01 | 2008-12-04 | Kaleo, Inc. | Devices, systems, and methods for medicament delivery |
| EP2316504B1 (en) | 2006-02-09 | 2019-09-25 | DEKA Products Limited Partnership | Fluid delivery system |
| CA2536845C (en) * | 2006-02-16 | 2009-10-27 | Pka Softtouch Corp. | Drug delivery device |
| US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
| TWI498137B (zh) * | 2006-06-30 | 2015-09-01 | Abbvie Biotechnology Ltd | 自動注射裝置 |
| EP2125075A2 (en) | 2007-01-22 | 2009-12-02 | Intelliject, Inc. | Medical injector with compliance tracking and monitoring |
| EP2990067B1 (en) | 2008-03-10 | 2019-09-04 | Antares Pharma, Inc. | Injector safety device |
| US8021344B2 (en) | 2008-07-28 | 2011-09-20 | Intelliject, Inc. | Medicament delivery device configured to produce an audible output |
| USD994111S1 (en) | 2008-05-12 | 2023-08-01 | Kaleo, Inc. | Medicament delivery device cover |
| AU2009256710B2 (en) * | 2008-06-11 | 2012-04-19 | Shl Group Ab | Medicament delivery device |
| EP2318075B1 (en) | 2008-08-05 | 2019-05-22 | Antares Pharma, Inc. | Multiple dosage injector |
| EP2401587A2 (en) | 2009-02-27 | 2012-01-04 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
| US9250106B2 (en) | 2009-02-27 | 2016-02-02 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
| WO2010108116A1 (en) | 2009-03-20 | 2010-09-23 | Antares Pharma, Inc. | Hazardous agent injection system |
| RU2524487C2 (ru) | 2009-04-29 | 2014-07-27 | Эббви Байотекнолоджи Лтд | Автоматическое инъекционное устройство |
| GB0910681D0 (en) * | 2009-06-19 | 2009-08-05 | Ucb Pharma Sa | Auto-injector |
| US8641671B2 (en) | 2009-07-30 | 2014-02-04 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| US20110046559A1 (en) | 2009-08-21 | 2011-02-24 | Becton Dickinson France S.A.S. | Syringe Assembly Having a Flexible or Slidable Flange |
| US8758301B2 (en) | 2009-12-15 | 2014-06-24 | Abbvie Biotechnology Ltd | Firing button for automatic injection device |
| RU2573042C2 (ru) | 2010-04-21 | 2016-01-20 | Эббви Байотекнолоджи Лтд. | Носимое устройство для автоматической инъекции для управляемой подачи терапевтических агентов |
| AU2012210170B2 (en) | 2011-01-24 | 2016-09-29 | Elcam Medical Agricultural Cooperative Association Ltd. | Injector |
| BR112013018773A2 (pt) | 2011-01-24 | 2016-10-25 | Abbvie Biotechnology Ltd | remoção de proteções de agulha de seringas e dispositivos de injeção automática |
| BR112013018905B1 (pt) | 2011-01-24 | 2021-07-13 | Abbvie Biotechnology Ltd | Dispositivos de injeção automática que têm superfícies de pega sobremoldadas. |
| US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
| US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
| US9084849B2 (en) | 2011-01-26 | 2015-07-21 | Kaleo, Inc. | Medicament delivery devices for administration of a medicament within a prefilled syringe |
| US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
| US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
| US9186459B2 (en) * | 2011-09-09 | 2015-11-17 | Merck Patent Gmbh | Auto-injector for epinephrine injection |
| SG11201400796TA (en) | 2011-09-22 | 2014-04-28 | Abbvie Inc | Automatic injection device |
| US8992476B2 (en) | 2011-09-22 | 2015-03-31 | Abbvie Inc. | Automatic injection device |
| DK2822618T3 (da) | 2012-03-06 | 2024-01-22 | Antares Pharma Inc | Forfyldt nål med brudkraftfunktion |
| JP5855522B2 (ja) * | 2012-04-27 | 2016-02-09 | 株式会社吉野工業所 | 定量シリンジ型噴出器 |
| AU2013203784A1 (en) | 2012-04-06 | 2013-10-24 | Kaushik J. Dave | Needle assisted jet injection administration of testosterone compositions |
| US9364611B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
| US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
| US9522235B2 (en) | 2012-05-22 | 2016-12-20 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
| EP2698180A1 (en) | 2012-08-15 | 2014-02-19 | Sanofi-Aventis Deutschland GmbH | Autoinjector |
| EP2926849B1 (en) * | 2012-11-30 | 2019-04-03 | Yoshino Kogyosho Co., Ltd. | Metered syringe-type ejector |
| WO2014106056A2 (en) | 2012-12-27 | 2014-07-03 | Kaleo, Inc. | Devices, systems and methods for locating and interacting with medicament delivery systems |
| JP2016507305A (ja) | 2013-02-11 | 2016-03-10 | アンタレス・ファーマ・インコーポレーテッド | トリガ力を低減した針支援式ジェット注射装置 |
| EP2968792B1 (en) | 2013-03-11 | 2019-05-15 | Antares Pharma, Inc. | Dosage injector with pinion system |
| WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
| US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
| EP2902061A1 (en) | 2014-01-30 | 2015-08-05 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device |
| US9517307B2 (en) | 2014-07-18 | 2016-12-13 | Kaleo, Inc. | Devices and methods for delivering opioid antagonists including formulations for naloxone |
| KR101628349B1 (ko) * | 2014-12-03 | 2016-06-08 | 김준호 | 시린지 교체형 자동투약기 |
| JP6573761B2 (ja) * | 2015-01-06 | 2019-09-11 | 小林製薬株式会社 | 押出器具 |
| WO2016134221A1 (en) | 2015-02-20 | 2016-08-25 | Regeneron Pharmaceuticals, Inc. | Syringe systems, piston seal systems, stopper systems, and methods of use and assembly |
| CA2980004C (en) | 2015-03-24 | 2023-10-10 | Kaleo, Inc. | Devices and methods for delivering a lyophilized medicament |
| JP6830067B2 (ja) | 2015-06-30 | 2021-02-17 | カレオ，インコーポレイテッド | プレフィルドシリンジ内の医薬を投与する自動注射器 |
| US10279123B2 (en) * | 2015-10-01 | 2019-05-07 | Noble International, Inc. | Microcartridge |
| KR101705050B1 (ko) * | 2015-10-15 | 2017-02-09 | (주)풍림파마텍 | 필러용 자동 주사장치 |
| USD818587S1 (en) | 2016-03-29 | 2018-05-22 | Abbevie Inc. | Automatic injection device |
| US20180015224A1 (en) | 2016-07-13 | 2018-01-18 | California Institute Of Technology | Dampers and Methods for Performing Measurements in an Autoinjector |
| WO2018119218A1 (en) | 2016-12-23 | 2018-06-28 | Kaleo, Inc. | Medicament delivery device and methods for delivering drugs to infants and children |
| CA3046354A1 (en) | 2017-01-17 | 2018-07-26 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and event detection |
| WO2020018433A1 (en) | 2018-07-16 | 2020-01-23 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and compliance detection |
| AU2020331302A1 (en) | 2019-08-09 | 2022-01-06 | Kaleo, Inc. | Devices and methods for delivery of substances within a prefilled syringe |
| CN114748778B (zh) * | 2021-01-11 | 2024-05-03 | 苏州纳生微电子有限公司 | 传动结构、应用传动结构的给液装置及其使用方法 |
| CN114917449B (zh) * | 2022-05-26 | 2024-02-27 | 曹清香 | 一种麻醉科用剂量可调的局部麻醉设备 |
Family Cites Families (512)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2459875A (en) | 1944-09-11 | 1949-01-25 | Marvin L Folkman | Syringe and ampoule |
| US2398544A (en) | 1945-01-06 | 1946-04-16 | Marshall L Lockhart | Hypodermic injector |
| US2565081A (en) | 1948-09-15 | 1951-08-21 | Emma C Maynes | Device for operating hypodermic syringes |
| US2591457A (en) | 1948-09-15 | 1952-04-01 | Emma C Maynes | Syringe operating device |
| DE902776C (de) | 1949-08-17 | 1954-01-28 | August Rooseboom | Selbsttaetiger Injektionsapparat mit Ampulle |
| US2701566A (en) | 1950-02-07 | 1955-02-08 | Becton Dickinson Co | Injection apparatus |
| BE531562A (ja) * | 1953-09-02 | |||
| US2960087A (en) | 1954-02-16 | 1960-11-15 | Auguste Rooseboom | Hypodermic injection apparatus |
| DK97966C (da) | 1954-10-27 | 1964-02-10 | Astra Apotekarnes Kem Fab | Injektionssprøjte. |
| US3055362A (en) | 1956-05-16 | 1962-09-25 | Auguste Rooseboom | Hypodermic injection apparatus |
| NL106573C (ja) | 1957-05-31 | |||
| US2888924A (en) | 1958-02-25 | 1959-06-02 | Russell P Dunmire | Hypodermic syringes |
| US3051173A (en) | 1960-05-12 | 1962-08-28 | Alvin P Johnson | Veterinary hypodermic syringe |
| US3330279A (en) | 1963-10-18 | 1967-07-11 | Sarnoff | Automatic hypodermic syringe |
| US3314428A (en) | 1963-12-04 | 1967-04-18 | Alvin P Johnson | Veterinary hypodermic syringe |
| US3403679A (en) | 1964-12-11 | 1968-10-01 | Secr Defence Brit | Hypodermic injection apparatus with a secondary capsule-collapsing means |
| US3496937A (en) | 1967-05-18 | 1970-02-24 | John E Balson | Hypodermic syringe |
| US3543603A (en) | 1968-01-10 | 1970-12-01 | Rex Chainbelt Inc | Automatic quick release mechanism |
| US3541663A (en) | 1968-08-21 | 1970-11-24 | Roman Szpur | Syringe needle attachment device |
| US3605743A (en) | 1968-10-14 | 1971-09-20 | Raul Olvera Arce | Hypodermic syringe |
| DE1957833A1 (de) | 1968-11-21 | 1970-07-02 | Maurice Steiner | Injektionsspritze,insbesondere von dem Patienten selbst gehandhabte Injektionsspritze |
| US3618603A (en) | 1969-01-29 | 1971-11-09 | Levenson M F | Syringe |
| BE755224A (fr) * | 1969-08-25 | 1971-02-24 | Philips Nv | Seringue d'injection |
| JPS5014835Y1 (ja) | 1969-11-18 | 1975-05-09 | ||
| DE2019296A1 (de) | 1970-04-22 | 1971-11-04 | Walter Dr Stein | Injektionsgeraet,insbesondere Injektionsspritze mit portionierter Packung |
| US3712301A (en) | 1971-01-11 | 1973-01-23 | Survival Technology | Gun type hypodermic injector with rapid cartridge displacement within holder |
| BE795162A (fr) * | 1972-02-10 | 1973-08-08 | Philips Nv | Injektie-inrichting |
| US3910260A (en) | 1972-03-01 | 1975-10-07 | Survival Technology | Method and apparatus of treating heart attack patients prior to the establishment of qualified direct contact personal care |
| US3797488A (en) | 1972-07-10 | 1974-03-19 | Ampoules Inc | Ampoule applicator with one-way clutch |
| US4004577A (en) | 1972-12-04 | 1977-01-25 | Survival Technology, Inc. | Method of treating heart attack patients prior to the establishment of qualified direct contact personal care |
| JPS5014835A (ja) | 1973-06-18 | 1975-02-17 | ||
| FR2237643B1 (ja) | 1973-07-17 | 1978-03-17 | Steiner Maurice | |
| US3882863A (en) | 1973-08-01 | 1975-05-13 | Survival Technology | Hypodermic injection device having cannula covered with resilient sheath |
| US3941130A (en) | 1975-03-18 | 1976-03-02 | Tibbs Robert C | Sequential trigger release for injection device |
| US4031893A (en) | 1976-05-14 | 1977-06-28 | Survival Technology, Inc. | Hypodermic injection device having means for varying the medicament capacity thereof |
| US4106770A (en) | 1976-09-01 | 1978-08-15 | Gray John M | Hypodermic syringe projectile |
| US4178928A (en) | 1977-08-10 | 1979-12-18 | Tischlinger Edward A | Self injector |
| SU787035A1 (ru) | 1978-01-11 | 1980-12-15 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Устройство дл введени лекарственных препаратов |
| US4202314A (en) | 1978-11-20 | 1980-05-13 | Busygin Valery P | Device for injection of medicinal preparations |
| US4226235A (en) | 1979-01-25 | 1980-10-07 | Survival Technology, Inc. | Plural injecting device |
| US4258713A (en) | 1979-07-23 | 1981-03-31 | Wardlaw Stephen C | Automatic disposable hypodermic syringe |
| US4261358A (en) | 1979-10-01 | 1981-04-14 | Walter Vargas | Automatic syringe plunger |
| US4275729A (en) | 1979-10-29 | 1981-06-30 | Jules Silver | Adjustable dosage syringe |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| AU549690B2 (en) | 1981-06-29 | 1986-02-06 | Sherwood Services Ag | Pin prick device to pierce skin |
| ATE15860T1 (de) | 1981-07-27 | 1985-10-15 | Duphar Int Res | Automatische injektionsspritze. |
| US4437859A (en) | 1981-08-03 | 1984-03-20 | Drs Infusion Systems, Inc. | Hydraulic syringe drive |
| US4394863A (en) | 1981-10-23 | 1983-07-26 | Survival Technology, Inc. | Automatic injector with cartridge having separate sequentially injectable medicaments |
| US4425120A (en) | 1982-04-15 | 1984-01-10 | Sampson Norma A | Shielded hypodermic syringe |
| EP0107874B1 (en) | 1982-10-27 | 1986-11-26 | Duphar International Research B.V | Automatic injection device |
| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| US4530695A (en) | 1982-12-31 | 1985-07-23 | N.J. Phillips Pty. Limited | Injector |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4578064A (en) | 1983-12-21 | 1986-03-25 | Survival Technology Inc. | Plural dosage automatic injector with improved safety |
| EP0154316B1 (en) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemically modified lymphokine and production thereof |
| US4610254A (en) | 1984-03-08 | 1986-09-09 | Physio-Control Corporation | Interactive portable defibrillator |
| US4619265A (en) | 1984-03-08 | 1986-10-28 | Physio-Control Corporation | Interactive portable defibrillator including ECG detection circuit |
| US4573976A (en) | 1984-05-24 | 1986-03-04 | Dolores A. Smith | Shielded needle |
| US4636202A (en) * | 1984-07-27 | 1987-01-13 | Syntex (U.S.A.) Inc. | Medicament applicator with plunger assembly and automatically-openable closure therefor |
| US4795433A (en) | 1985-05-20 | 1989-01-03 | Survival Technology, Inc. | Automatic injector for emergency treatment |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4678461A (en) | 1984-11-01 | 1987-07-07 | Survival Technology, Inc. | Automatic injector with improved glass container protector |
| EP0186916B1 (en) | 1984-11-02 | 1988-12-21 | Duphar International Research B.V | Automatic injection device |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4627445A (en) | 1985-04-08 | 1986-12-09 | Garid, Inc. | Glucose medical monitoring system |
| US4723937A (en) | 1985-05-20 | 1988-02-09 | Survival Technology, Inc. | Plural dosage automatic injector with a by-pass fitment |
| US4689042A (en) | 1985-05-20 | 1987-08-25 | Survival Technology, Inc. | Automatic medicament ingredient mixing and injecting apparatus |
| EP0242373A1 (de) | 1985-10-11 | 1987-10-28 | Physionic Gesellschaft Für Medizin- Und Systemtechnik Gmbh | Injektionsspritze |
| ES2017924B3 (es) | 1985-10-11 | 1991-03-16 | Duphar Int Res B V | Inyector automatico. |
| DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
| US4640686A (en) | 1986-02-24 | 1987-02-03 | Survival Technology, Inc. | Audible signal autoinjector training device |
| US4664653A (en) | 1986-02-24 | 1987-05-12 | Sagstetter William E | Manually operated reusable injection apparatus |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| EP0245895B1 (en) | 1986-05-15 | 1991-09-18 | Duphar International Research B.V | Automatic injector |
| DE3631229A1 (de) | 1986-09-13 | 1988-03-24 | Basf Ag | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
| DE3645245C2 (de) | 1986-11-14 | 1994-01-27 | Haselmeier Wilhelm Fa | Injektionsgerät |
| US4795432A (en) | 1987-02-19 | 1989-01-03 | Karczmer Claude M | Shield assembly for hypodermic injection devices |
| DE3709783C1 (de) | 1987-03-25 | 1988-04-14 | Blendax Werke Schneider Co | Dosierspritze |
| DE3715340C2 (de) | 1987-05-08 | 1995-10-19 | Haselmeier Wilhelm Fa | Injektionsgerät |
| DE3715258C2 (de) | 1987-05-08 | 1996-10-31 | Haselmeier Wilhelm Fa | Injektionsgerät |
| US4927416A (en) | 1987-12-02 | 1990-05-22 | National Medical Device Corporation | User-protective hypodermic syringe holder |
| GB8809115D0 (en) | 1988-04-18 | 1988-05-18 | Turner R C | Syringes |
| JPH025504A (ja) | 1988-06-24 | 1990-01-10 | Matsushita Electric Ind Co Ltd | 電圧非直線抵抗体 |
| WO1990001047A1 (en) | 1988-07-28 | 1990-02-08 | Idemitsu Petrochemical Company Limited | Rubber-modified styrene resin composition |
| GB8819977D0 (en) | 1988-08-23 | 1988-09-21 | Medimech Ltd | Automatic injectors |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US4902279A (en) | 1988-10-05 | 1990-02-20 | Autoject Systems Inc. | Liquid medicament safety injector |
| US5244465A (en) | 1988-10-19 | 1993-09-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Reusable injection device for distributing a preselected dose |
| US4929237A (en) | 1988-11-07 | 1990-05-29 | David Medway | Hypodermic needle protection device |
| US4955868A (en) | 1988-11-28 | 1990-09-11 | Edward Klein | Disposable safety medical syringe |
| IT1227658B (it) | 1988-12-01 | 1991-04-23 | Vittorio Boschetti B | Siringa monouso con rientro e blocco dell'ago a fine iniezione a scopo di evitare il reimpiego |
| JP2989002B2 (ja) | 1988-12-22 | 1999-12-13 | キリン―アムジエン・インコーポレーテツド | 化学修飾顆粒球コロニー刺激因子 |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2019792A6 (es) | 1990-01-17 | 1991-07-01 | Caralt Batlle Jaime | Jeringuilla hipodrmica de un solo uso. |
| ES2009709A6 (es) | 1989-01-24 | 1989-10-01 | Villar Pascual Jose Antonio | Jeronguilla de seguridad monouso. |
| US4923447A (en) | 1989-02-17 | 1990-05-08 | Morgan Michael W | Syringe assembly |
| ATE84205T1 (de) | 1989-03-28 | 1993-01-15 | Duphar Int Res | Vorgefuellte injektionsvorrichtung mit einem fass, das mit einer fluessigen diazepam-formulierung gefuellt ist. |
| US4966592A (en) | 1989-05-05 | 1990-10-30 | Burns Cameron A | Protective sleeve for hypodermic needle |
| USD322479S (en) | 1989-06-02 | 1991-12-17 | Terumo Kabushiki Kaisha | Holder for lancet |
| US4994034A (en) | 1989-07-11 | 1991-02-19 | Botich Michael J | Retractable needle hypodermic syringe system |
| US5407431A (en) | 1989-07-11 | 1995-04-18 | Med-Design Inc. | Intravenous catheter insertion device with retractable needle |
| US5085641A (en) | 1989-07-17 | 1992-02-04 | Survival Technology, Inc. | Conveniently carried frequent use auto-injector with improved cap structure |
| US5085642A (en) | 1989-07-17 | 1992-02-04 | Survival Technology, Inc. | Conveniently carried frequent use autoinjector |
| US5102393A (en) | 1989-07-17 | 1992-04-07 | Survival Technology, Inc. | Autoinjector converted from intramuscular to subcutaneous mode of injection |
| US6498237B2 (en) | 1989-08-07 | 2002-12-24 | Peptech Limited | Tumor necrosis factor antibodies |
| US5959087A (en) | 1989-08-07 | 1999-09-28 | Peptide Technology, Ltd. | Tumour necrosis factor binding ligands |
| WO1991003553A1 (en) | 1989-09-05 | 1991-03-21 | Immunex Corporation | TUMOR NECROSIS FACTOR-α AND -β RECEPTORS |
| CN2077717U (zh) * | 1989-10-05 | 1991-05-29 | 薛建仁 | 医用一次性输液瓶及输液控制器 |
| EP0423864A1 (en) | 1989-10-16 | 1991-04-24 | Duphar International Research B.V | Training device for an automatic injector |
| GB8926825D0 (en) | 1989-11-28 | 1990-01-17 | Glaxo Group Ltd | Device |
| ATE112690T1 (de) | 1990-03-08 | 1994-10-15 | Blue Star Corp Sa | Spritze mit sich automatisch zurückziehender nadel. |
| GB2243552A (en) | 1990-03-21 | 1991-11-06 | Transfertec Limited | Improvements in or relating to single-use syringes |
| US5092843A (en) | 1990-04-12 | 1992-03-03 | Survival Technology, Inc. | Dispersion multichamber auto-injector |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ES2082052T3 (es) | 1990-07-19 | 1996-03-16 | Nardino Righi | Jeringuilla de seguridad, de un solo uso. |
| DK285990A (da) | 1990-11-30 | 1992-05-31 | Nujenko Pty Ltd | Sproejteenhed |
| ATE164395T1 (de) | 1990-12-03 | 1998-04-15 | Genentech Inc | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
| AU114410S (en) | 1990-12-21 | 1992-06-29 | Glaxo Group Ltd | An injector |
| GB9100819D0 (en) * | 1991-01-15 | 1991-02-27 | Medimech Int Ltd | Subcutaneous injector |
| US5376080A (en) | 1991-01-30 | 1994-12-27 | Petrussa; Gian L. | Single use retractable needle syringe |
| DK1820858T3 (da) | 1991-03-01 | 2009-11-02 | Dyax Corp | Kimært protein omfatende mikroprotein med to eller flere disulfidbindinger og udförelsesformer deraf |
| US5656272A (en) | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| CA2108147C (en) | 1991-04-10 | 2009-01-06 | Angray Kang | Heterodimeric receptor libraries using phagemids |
| CN2094999U (zh) * | 1991-04-13 | 1992-02-05 | 张卫 | 自动注射枪 |
| GB9111600D0 (en) * | 1991-05-30 | 1991-07-24 | Owen Mumford Ltd | Improvements relating to injection devices |
| EP0518416A1 (en) | 1991-06-13 | 1992-12-16 | Duphar International Research B.V | Injection device |
| RU2004256C1 (ru) | 1991-06-26 | 1993-12-15 | Липов Борис Петрович, Сафронов Игорь Николаевич | Инъектор |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| DE59202070D1 (de) | 1991-07-24 | 1995-06-08 | Medico Dev Investment Co | Injektor. |
| US5259840A (en) | 1991-09-03 | 1993-11-09 | Boris Craig R | Locking syringe |
| DE69229477T2 (de) | 1991-09-23 | 1999-12-09 | Cambridge Antibody Tech | Methoden zur Herstellung humanisierter Antikörper |
| US5242240A (en) | 1991-10-17 | 1993-09-07 | Minnesota Scientific, Inc. | Clamping device for a surgical retractor |
| USD346219S (en) | 1991-11-25 | 1994-04-19 | Actimed Plast AB | Erection pump |
| US5263934A (en) | 1991-11-28 | 1993-11-23 | Haak Abraham Van Den | Stroke limiting syringe with retractable needle |
| DK194291D0 (da) | 1991-11-29 | 1991-11-29 | Novo Nordisk As | Sproejte til automatisk injektion. |
| EP0620748B1 (en) | 1992-01-07 | 2010-07-28 | Meridian Medical Technologies, Inc. | Automatic injectors |
| GB9200219D0 (en) | 1992-01-07 | 1992-02-26 | Medimech Int Ltd | Automatic injectors |
| AT398037B (de) | 1992-01-10 | 1994-08-25 | Med Plastic Ag | Vorrichtung zur selbst-injektion |
| US5201708A (en) | 1992-02-03 | 1993-04-13 | Timothy A. Kershenstine | Self-locking safety syringe |
| ATE138582T1 (de) | 1992-03-27 | 1996-06-15 | Duphar Int Res | Automatische spritze |
| WO1993019751A1 (en) | 1992-04-02 | 1993-10-14 | Smithkline Beecham Corporation | Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor |
| US5267972A (en) | 1992-07-20 | 1993-12-07 | Anderson Wayne W | Hypodermic syringe with needle guard |
| US5267963A (en) | 1992-08-21 | 1993-12-07 | Nicholas Bachynsky | Medication injection device |
| AU670125B2 (en) | 1992-09-15 | 1996-07-04 | Immunex Corporation | Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists |
| GB9219849D0 (en) | 1992-09-19 | 1992-10-28 | Hypoguard Uk Ltd | Device |
| US5224936A (en) | 1992-10-15 | 1993-07-06 | Brian Gallagher | Automatic self-protecting hypodermic needle assembly |
| WO1994008609A1 (en) | 1992-10-15 | 1994-04-28 | Dana-Farber Cancer Institute, Inc. | TREATMENT OF INSULIN RESISTANCE IN OBESITY LINKED TYPE II DIABETES USING ANTAGONISTS TO TNF-α FUNCTION |
| US5295975A (en) | 1992-10-28 | 1994-03-22 | Lockwood Jr Hanford N | Hypodermic needle safety device with sliding outer cover |
| US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
| GB9223183D0 (en) | 1992-11-05 | 1992-12-16 | Medimech Int Ltd | Improvements related to auto injectors |
| US5378233A (en) | 1992-11-18 | 1995-01-03 | Habley Medical Technology Corporation | Selected dose pharmaceutical dispenser |
| US5681291A (en) | 1992-11-19 | 1997-10-28 | Tebro S.A. | Disposable auto-injector for prefilled syringes |
| US5320609A (en) | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
| IT1256577B (it) | 1992-12-11 | 1995-12-11 | Ermanno Greco | Dispositivo predisposto per la somministrazione automatica di un farmaco per via intradermica. |
| US5346480A (en) | 1992-12-14 | 1994-09-13 | Q-Med, Inc. | Syringe with retractable needle |
| US5298024A (en) | 1992-12-28 | 1994-03-29 | Frank Richmond | Multi-liquid medicament delivery system with reflex valves |
| FR2701211B1 (fr) | 1993-02-08 | 1995-05-24 | Aguettant Lab | Instrument doseur, notamment d'injection |
| US5383865A (en) | 1993-03-15 | 1995-01-24 | Eli Lilly And Company | Medication dispensing device |
| DE69427226T2 (de) | 1993-03-24 | 2001-08-30 | Owen Mumford Ltd | Vorrichtung zur injektion |
| DK55693D0 (da) | 1993-05-13 | 1993-05-13 | Radiometer As | Afskydningsmekanisme til afskydning af en kanyle placeret i forbindelse med en beholder, samt et beholderemne omfattende en saadan afskydningsmekanisme |
| US5358489A (en) | 1993-05-27 | 1994-10-25 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
| US5540664A (en) | 1993-05-27 | 1996-07-30 | Washington Biotech Corporation | Reloadable automatic or manual emergency injection system |
| US5433712A (en) | 1993-06-10 | 1995-07-18 | Donald E. Stiles | Self-sheathing hypodermic syringe |
| US5425715A (en) | 1993-08-05 | 1995-06-20 | Survival Technology, Inc. | Reloadable injector |
| US5620421A (en) * | 1993-12-09 | 1997-04-15 | Schmitz; William L. | Syringe injector system |
| FR2715071B1 (fr) | 1994-01-17 | 1996-03-01 | Aguettant Lab | Injecteur automatique de médicament. |
| US5478316A (en) | 1994-02-02 | 1995-12-26 | Becton, Dickinson And Company | Automatic self-injection device |
| DK1228777T3 (da) | 1994-05-30 | 2004-03-01 | B D Medico S A R L | Injektionsudstyr |
| GB9412301D0 (en) | 1994-06-17 | 1994-08-10 | Safe T Ltd | Hollow-needle drugs etc applicators |
| US5645534A (en) | 1994-06-24 | 1997-07-08 | Becton Dickinson And Company | Time of last injection indicator for medication delivery pen |
| DE69534405T2 (de) | 1994-07-01 | 2006-03-09 | Edwards Lifesciences Corp., Irvine | Vorrichtung zum gewinnen von autologen, mikrovaskulären endothelialen zellen enthaltendem fettgewebe |
| CN2224628Y (zh) * | 1994-10-26 | 1996-04-17 | 周正龙 | 双簧式自动注射器 |
| US5637094A (en) | 1994-11-04 | 1997-06-10 | Pos-T-Vac, Inc. | Multiple dosage syringe |
| RU2069584C1 (ru) | 1994-11-24 | 1996-11-27 | Виктор Владимирович Барелко | Катализатор для химических процессов, например конверсии аммиака, окисления углеводородов, диоксида серы, очистки выхлопных газов |
| US5993421A (en) | 1994-12-02 | 1999-11-30 | Science Incorporated | Medicament dispenser |
| GB9504878D0 (en) | 1995-03-10 | 1995-04-26 | Weston Medical Ltd | Viscously coupled actuator |
| US6319011B1 (en) | 1995-04-06 | 2001-11-20 | Michael J. Motti | Automatic training defibrillator simulator and method |
| FR2733155B1 (fr) | 1995-04-18 | 1997-09-19 | Tebro | Auto-injecteur rechargeable |
| FR2736553B1 (fr) * | 1995-07-12 | 1998-01-09 | Soc Et Et D Applic Tech Sedat | Seringue d'injection, notamment de produits medicaux liquides, a protecteur d'aiguille mobile |
| US5797969A (en) | 1995-08-01 | 1998-08-25 | Survivalink Corporation | One button lid activated automatic external defibrillator |
| US5645571B1 (en) | 1995-08-01 | 1999-08-24 | Surviva Link Corp | Automated external defibrillator with lid activated self-test system |
| EP1637181A1 (en) | 1995-08-08 | 2006-03-22 | Cardiac Science, Inc. | Automated external defibrillator |
| US5591138A (en) | 1995-08-10 | 1997-01-07 | Vaillancourt; Vincent L. | Protected needle assembly |
| US5735818A (en) | 1995-10-11 | 1998-04-07 | Science Incorporated | Fluid delivery device with conformable ullage |
| US5658259A (en) | 1995-10-19 | 1997-08-19 | Meridian Medical Technologies, Inc. | Dental cartridge assembly auto-injector with protective needle cover |
| US5567160A (en) | 1995-10-26 | 1996-10-22 | Survival Technology, Inc. | Autoinjector training device |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| US5807335A (en) | 1995-12-22 | 1998-09-15 | Science Incorporated | Fluid delivery device with conformable ullage and fill assembly |
| US5634906A (en) | 1995-12-27 | 1997-06-03 | Habley Medical Technology Corporation | Needle hiding shield for a dose metering syringe |
| MX336813B (es) | 1996-02-09 | 2016-02-02 | Abbvie Biotechnology Ltd | Anticuerpos humanos que ligan el tnfa humano. |
| DE19604838A1 (de) | 1996-02-12 | 1997-08-14 | Alfred Von Schuckmann | Vorrichtung zum Ausgeben von Flüssigkeit in abgeteilten Mengen |
| US6277098B1 (en) | 1996-03-12 | 2001-08-21 | Novo Nordisk A/S | Injection device with electronic presentation of set doses |
| US5817111A (en) | 1996-03-28 | 1998-10-06 | Riza; Erol D. | Open loop suture snare |
| IT1284642B1 (it) | 1996-05-02 | 1998-05-21 | Ermanno Greco | Perfezionamenti alle siringhe automatiche per iniezione |
| EP1579814A3 (en) | 1996-05-17 | 2006-06-14 | Roche Diagnostics Operations, Inc. | Methods and apparatus for sampling and analyzing body fluid |
| GB9612724D0 (en) | 1996-06-18 | 1996-08-21 | Owen Mumford Ltd | Improvements relating to injection devices |
| WO1998001172A1 (de) | 1996-07-05 | 1998-01-15 | Disetronic Licensing Ag | Injektionsgerät zum injizieren von flüssigkeit |
| US5843036A (en) | 1996-08-23 | 1998-12-01 | Becton Dickinson And Company | Non-dosing cartridge for an injection device |
| US6325066B1 (en) | 1996-08-26 | 2001-12-04 | Charles B. Hughes | Bladder and bowel training system with removable voice module system |
| US5845644A (en) | 1996-08-26 | 1998-12-08 | Hughes; Charles B. | Bladder and bowel training system |
| US6593456B1 (en) | 1996-11-06 | 2003-07-15 | The Regents Of The University Of California | Tumor necrosis factor receptor releasing enzyme |
| BR9712900A (pt) | 1996-11-06 | 2000-11-28 | Univ California | Enzima liberadora de receptor de fator de necrose de tumor isolado, composições que compreendem a enzima e métodos de utilização da mesma |
| SE9604162D0 (sv) | 1996-11-13 | 1996-11-13 | Astra Ab | Membrane |
| US6203530B1 (en) | 1997-01-28 | 2001-03-20 | Pos-T-Vac, Inc. | Auto-injection device |
| US20070142776A9 (en) * | 1997-02-05 | 2007-06-21 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
| US5860957A (en) | 1997-02-07 | 1999-01-19 | Sarcos, Inc. | Multipathway electronically-controlled drug delivery system |
| BR9700930A (pt) | 1997-02-07 | 1998-12-08 | Rhone Poulenc Rorer Gmbh | Unidade para venda que se destina a aplicação parenteral um dispositivo para a execução da aplicação parenteral bem como uma unidade de recarga destinada á unidade para venda acima mencionada |
| AU6719198A (en) | 1997-02-12 | 1998-09-08 | Sergio Restelli | Disposable safety syringe |
| DE29703820U1 (de) | 1997-03-03 | 1998-07-02 | Medico Dev Investment Co | Injektionsgerät |
| US6277097B1 (en) | 1997-03-25 | 2001-08-21 | Novo Nordisk A/S | Injection system |
| US6454746B1 (en) | 1997-06-04 | 2002-09-24 | Eli Lilly And Company | Medication delivery apparatus |
| US6500150B1 (en) | 1997-06-16 | 2002-12-31 | Elan Pharma International Limited | Pre-filled drug-delivery device and method of manufacture and assembly of same |
| US6979307B2 (en) | 1997-06-24 | 2005-12-27 | Cascade Medical Enterprises Llc | Systems and methods for preparing autologous fibrin glue |
| GB9714948D0 (en) | 1997-07-16 | 1997-09-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| GB9716065D0 (en) | 1997-07-31 | 1997-10-01 | Owen Mumford Ltd | Improvements relating to injection devices |
| CA2300930C (en) | 1997-08-21 | 2007-10-16 | Owen Mumford Limited | Improvements relating to injection devices |
| AU9202398A (en) | 1997-09-29 | 1999-04-23 | Becton Dickinson & Company | Injection device and drug cartridge for preventing cross-use of the device and drug cartridge |
| US5931817A (en) | 1997-09-12 | 1999-08-03 | Becton Dickinson And Company | Pen needle assembly |
| JP3968445B2 (ja) * | 1997-09-16 | 2007-08-29 | 株式会社アルテ | プレフィルドシリンジ |
| US6149626A (en) | 1997-10-03 | 2000-11-21 | Bachynsky; Nicholas | Automatic injecting syringe apparatus |
| WO1999022792A1 (en) | 1997-11-03 | 1999-05-14 | Ermanno Greco | Self-injection device |
| FR2770404B1 (fr) | 1997-11-05 | 2000-01-28 | Sedat | Injecteur automatique a retraction d'aiguille en fin d'injection |
| IL136714A0 (en) | 1997-12-16 | 2001-06-14 | Meridian Medical Technologies | Automatic injector for administrating a medicament |
| IT1304761B1 (it) | 1998-01-20 | 2001-03-29 | Nardino Righi | Siringa monouso di sicurezza. |
| DE29801168U1 (de) | 1998-01-24 | 1999-08-12 | Medico Dev Investment Co | Injektionsgerät |
| FR2774294B1 (fr) | 1998-02-04 | 2000-04-14 | Marc Brunel | Dispositif d'injection automatique d'une dose de produit medicamenteux |
| US7056306B1 (en) | 1998-02-05 | 2006-06-06 | Mdc Investment Holdings, Inc. | Fluid sampling device with retractable needle |
| GB9803084D0 (en) | 1998-02-14 | 1998-04-08 | Owen Mumford Ltd | Improvements relating to medical injection devices |
| FI109272B (fi) | 1998-02-26 | 2002-06-28 | Raimo Juselius | Ottotapahtuman ilmaisinlaite ja menetelmä ottotapahtuman ilmaisemiseksi |
| US6319233B1 (en) | 1998-04-17 | 2001-11-20 | Becton, Dickinson And Company | Safety shield system for prefilled syringes |
| GB9808408D0 (en) | 1998-04-18 | 1998-06-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| DE19821933C1 (de) | 1998-05-15 | 1999-11-11 | Disetronic Licensing Ag | Vorrichtung zur Verabreichung eines injizierbaren Produkts |
| DE19822031C2 (de) | 1998-05-15 | 2000-03-23 | Disetronic Licensing Ag | Autoinjektionsgerät |
| SE9803662D0 (sv) | 1998-10-26 | 1998-10-26 | Pharmacia & Upjohn Ab | Autoinjector |
| USD428651S (en) | 1998-10-26 | 2000-07-25 | Pharmacia & Upjohn Ab | Autoinjector for standardized single dose syringes |
| US6125299A (en) | 1998-10-29 | 2000-09-26 | Survivalink Corporation | AED with force sensor |
| US6059756A (en) * | 1998-11-04 | 2000-05-09 | Yeh; Song-Hwa | Safety injection device |
| WO2000029049A1 (en) | 1998-11-13 | 2000-05-25 | Elan Pharma International Limited | Drug delivery systems and methods |
| US6334070B1 (en) | 1998-11-20 | 2001-12-25 | Medtronic Physio-Control Manufacturing Corp. | Visual and aural user interface for an automated external defibrillator |
| US20060058848A1 (en) | 1998-11-20 | 2006-03-16 | Medtronic Emergency Response Systems, Inc. | AED with user inputs in response to prompts |
| US6312412B1 (en) | 1998-12-02 | 2001-11-06 | V. C. Saied, M.D. | Apparatus and method for painless intramuscular or subcutaneous injections |
| US6872080B2 (en) | 1999-01-29 | 2005-03-29 | Cardiac Science, Inc. | Programmable AED-CPR training device |
| GB9903475D0 (en) | 1999-02-17 | 1999-04-07 | Owen Mumford Ltd | Improvements relating to injection devices |
| PT1198263E (pt) | 1999-07-27 | 2003-09-30 | Pharma Consult Gmbh | Dispositivo para a injeccao automatica de liquidos injectaveis |
| US6213987B1 (en) | 1999-08-02 | 2001-04-10 | Michael N. Hirsch | Shroud for a used hypodermic syringe needle |
| US6277099B1 (en) | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
| DE60015996T2 (de) | 1999-09-07 | 2005-11-10 | Computer Controlled Syringe Inc., London | Zurückziehbare nadelanordnung |
| US6102896A (en) | 1999-09-08 | 2000-08-15 | Cambridge Biostability Limited | Disposable injector device |
| US7011650B2 (en) * | 1999-09-09 | 2006-03-14 | Paradigm Medical, Llc | Multiple-dose syringe with collapsible container |
| US20020091361A1 (en) * | 1999-09-09 | 2002-07-11 | Rosoff Jack P. | Multiple-dose syringe |
| AU7578600A (en) | 1999-09-13 | 2001-04-17 | Vitro Diagnostics, Inc. | Multi-dose syringe driver |
| US6171285B1 (en) | 1999-10-06 | 2001-01-09 | R. Steven Johnson | Retractable syringe |
| US6673035B1 (en) | 1999-10-22 | 2004-01-06 | Antares Pharma, Inc. | Medical injector and medicament loading system for use therewith |
| ES2332595T3 (es) | 1999-11-18 | 2010-02-09 | Tyco Healthcare Group Lp | Envoltura automatica de seguridad para agujas. |
| GB9927715D0 (en) | 1999-11-24 | 2000-01-19 | Safe T Ltd | Hollow-needle devices |
| EP1233803B1 (en) | 1999-11-29 | 2006-02-15 | MDC Investment Holdings, Inc. | Combination safety needle assembly and medical apparatus |
| US7483743B2 (en) | 2000-01-11 | 2009-01-27 | Cedars-Sinai Medical Center | System for detecting, diagnosing, and treating cardiovascular disease |
| US8298150B2 (en) | 2000-01-11 | 2012-10-30 | Cedars-Sinai Medical Center | Hemodynamic waveform-based diagnosis and treatment |
| US6328699B1 (en) | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
| RU2169584C1 (ru) | 2000-01-17 | 2001-06-27 | Лисовой Дмитрий Григорьевич | Инъектор |
| GB0003790D0 (en) | 2000-02-18 | 2000-04-05 | Astrazeneca Uk Ltd | Medical device |
| ATE297769T1 (de) * | 2000-02-23 | 2005-07-15 | Hospira Inc | Spritzen und spritzensysteme zur selektiven verabreichung von kontrollierten mengen einer therapeutischen substanz |
| DE10009814B4 (de) | 2000-03-01 | 2008-03-06 | Tecpharma Licensing Ag | Einweg-Injektorkappe |
| DE10009815B4 (de) | 2000-03-01 | 2009-07-16 | Tecpharma Licensing Ag | Injektionsgerät mit einer Nadelabdeckung |
| US6322540B1 (en) | 2000-03-10 | 2001-11-27 | International Technology Group | Safe needle device for syringe |
| US6475194B2 (en) | 2000-04-05 | 2002-11-05 | Gem Plastics, Inc. | Safety syringe |
| US6547763B2 (en) | 2000-05-18 | 2003-04-15 | Novo Nordisk A/S | Dose display for injection device |
| USD461555S1 (en) | 2000-05-25 | 2002-08-13 | Jean Marc Binet | Safety syringe |
| ES2269418T3 (es) | 2000-06-08 | 2007-04-01 | Meridian Medical Technologies, Inc. | Montaje de inyector automatico para material liquido/seco. |
| US6517517B1 (en) | 2000-06-08 | 2003-02-11 | Mayo Foundation For Medical Education And Research | Automated injection device for administration of liquid medicament |
| US6502699B1 (en) | 2000-06-21 | 2003-01-07 | Robert L. Watson | Method and kit for making injections and withdrawing blood without the use of protective gloves |
| NO312059B1 (no) | 2000-06-23 | 2002-03-11 | Syringus As | En kanyletildekkingsmekanisme, en kanyleholder og en injeksjonsspröyte |
| EP1317296A4 (en) | 2000-07-28 | 2004-11-17 | Mdc Invest Holdings Inc | MEDICAL DEVICE WITH RETRACTABLE NEEDLE FOR THE INJECTION OF FLUIDS FROM A PRE-FILLED CARTRIDGE |
| US6986760B2 (en) | 2000-08-02 | 2006-01-17 | Becton, Dickinson And Company | Pen needle and safety shield system |
| UA81743C2 (uk) | 2000-08-07 | 2008-02-11 | Центокор, Инк. | МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ |
| WO2002017996A1 (en) | 2000-08-29 | 2002-03-07 | Novo Nordisk A/S | Automatic injection device with torsion function for retraction of needle |
| US6413237B1 (en) | 2000-08-31 | 2002-07-02 | Becton, Dickinson And Company | Hypodermic syringe with selectively retractable needle |
| US6964647B1 (en) | 2000-10-06 | 2005-11-15 | Ellaz Babaev | Nozzle for ultrasound wound treatment |
| US6953445B2 (en) | 2000-10-10 | 2005-10-11 | Meridian Medical Technologies, Inc. | Wet/dry automatic injector assembly |
| FR2815543B1 (fr) | 2000-10-19 | 2003-10-24 | Sedat | Seringue d'auto-injection d'un melange extemporane |
| US20040229854A1 (en) | 2000-11-28 | 2004-11-18 | Pieter Haan De | Immediate release dosage form for HRT |
| SE518981C2 (sv) | 2000-12-14 | 2002-12-17 | Shl Medical Ab | Autoinjektor |
| US6387078B1 (en) | 2000-12-21 | 2002-05-14 | Gillespie, Iii Richard D. | Automatic mixing and injecting apparatus |
| EP1345968A2 (en) | 2000-12-28 | 2003-09-24 | Altus Biologics Inc. | Crystals of whole antibodies and fragments thereof and methods for making and using them |
| USD453569S1 (en) | 2001-01-08 | 2002-02-12 | Pharmacia Ab | Injection device |
| US6673049B2 (en) | 2001-02-15 | 2004-01-06 | Disetronic Licensing Ag | Injection device for injecting fluid |
| AUPR373001A0 (en) | 2001-03-14 | 2001-04-12 | Glenord Pty Ltd | Improved non-reusable syringe |
| WO2002096461A1 (en) | 2001-05-25 | 2002-12-05 | Abbott Gmbh & Co. Kg | Use of anti-tnf antibodies as drugs in treating septic disorders of anemic patients |
| CA2385745C (en) | 2001-06-08 | 2015-02-17 | Abbott Laboratories (Bermuda) Ltd. | Methods of administering anti-tnf.alpha. antibodies |
| US6802827B2 (en) | 2001-06-26 | 2004-10-12 | Stig O. Andersson | Hypodermic implant device |
| GB0118419D0 (en) | 2001-07-28 | 2001-09-19 | Owen Mumford Ltd | Improvements relating to injection devices |
| EP1281410A1 (en) | 2001-08-03 | 2003-02-05 | Sergio Restelli | Automatic safety syringe |
| US7163943B2 (en) | 2001-09-21 | 2007-01-16 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| FR2830765B1 (fr) | 2001-10-15 | 2004-07-23 | Plastic Omnium Cie | Dispositif de securite pour une seringue |
| US6494863B1 (en) | 2001-10-15 | 2002-12-17 | Retractable Technologies, Inc. | One-use retracting syringe with positive needle retention |
| JP2003122442A (ja) | 2001-10-16 | 2003-04-25 | Sony Corp | ソフトウェア・ダウンロードシステムのための無線データ通信方法および装置 |
| US6796967B2 (en) | 2001-10-22 | 2004-09-28 | Nps Pharmaceuticals, Inc. | Injection needle assembly |
| US7569035B1 (en) | 2001-11-02 | 2009-08-04 | Meridian Medical Technologies, Inc. | Automatic injector with anti-coring needle |
| AUPR867901A0 (en) | 2001-11-05 | 2001-11-29 | University of Newcastel Research Associates Limited, The | 'Liquid dispenser' |
| US7011649B2 (en) | 2001-11-09 | 2006-03-14 | Alza Corporation | Collapsible syringe cartridge |
| US20030105430A1 (en) | 2001-11-30 | 2003-06-05 | Elan Pharma International Limited Wil House | Automatic injector |
| GB0200637D0 (en) | 2002-01-12 | 2002-02-27 | Dca Design Int Ltd | Improvements in and relating to medicament injection apparatus |
| US6872194B2 (en) | 2002-01-31 | 2005-03-29 | Safety Syringes, Inc. | Disposable self-shielding syringe guard |
| EP1334740A1 (en) | 2002-02-11 | 2003-08-13 | Sergio Restelli | Glass safety syringe and relative safety kit for glass syringe |
| WO2003070296A2 (en) | 2002-02-15 | 2003-08-28 | Antares Pharma, Inc. | Injector with bypass channel |
| US20030161828A1 (en) | 2002-02-19 | 2003-08-28 | Abbott Gmbh & Co. Kg | Use of TNF antagonists as drugs for the treatment of patients with an inflammatory reaction and without suffering from total organ failure |
| US7033338B2 (en) | 2002-02-28 | 2006-04-25 | Smiths Medical Md, Inc. | Cartridge and rod for axially loading medication pump |
| GB0205066D0 (en) | 2002-03-05 | 2002-04-17 | Owen Mumford Ltd | Improvements relating to injection devices |
| AU2003208948A1 (en) | 2002-03-13 | 2003-09-29 | Eli Lilly And Company | Method of treating a medical condition with a portable medication delivery device |
| CN101143221A (zh) | 2002-03-15 | 2008-03-19 | 布赖汉姆妇女医院 | 适合治疗剂全身性递送的中央气道给药 |
| US7678084B2 (en) | 2002-03-18 | 2010-03-16 | Eli Lilly And Company | Medication dispensing apparatus with gear set for mechanical advantage |
| US20030187401A1 (en) | 2002-03-27 | 2003-10-02 | Safety Syringes, Inc. | Syringe with integral safety system |
| US6976976B2 (en) | 2002-03-27 | 2005-12-20 | Safety Syringes, Inc. | Syringe with needle guard injection device |
| US7004929B2 (en) | 2002-03-29 | 2006-02-28 | Mdc Investment Holdings, Inc. | Safety pre-filled cartridge injector |
| WO2003093108A1 (en) * | 2002-04-05 | 2003-11-13 | Comar, Inc. | Dispenser for medicaments and method and apparatus for making same |
| US20040009172A1 (en) | 2002-04-26 | 2004-01-15 | Steven Fischkoff | Use of anti-TNFalpha antibodies and another drug |
| US20030206898A1 (en) | 2002-04-26 | 2003-11-06 | Steven Fischkoff | Use of anti-TNFalpha antibodies and another drug |
| GB2388033A (en) * | 2002-05-02 | 2003-11-05 | Pa Consulting Services | Automatic injection device |
| MXPA04010861A (es) | 2002-05-02 | 2005-07-14 | Pa Knowledge Ltd | Dispositivo para inyeccion. |
| US7247151B2 (en) | 2002-05-09 | 2007-07-24 | Adam Slawson | Injector with shielded needle |
| US6808507B2 (en) | 2002-05-10 | 2004-10-26 | Cambridge Biostability Ltd. | Safety injectors |
| US8527044B2 (en) | 2002-05-15 | 2013-09-03 | Physio-Control, Inc. | User interface method and apparatus for a medical device |
| GB0211294D0 (en) | 2002-05-17 | 2002-06-26 | Owen Mumford Ltd | Improvements relating to injection devices |
| US6979316B1 (en) | 2002-05-23 | 2005-12-27 | Seedlings Life Science Ventures Llc | Apparatus and method for rapid auto-injection of medication |
| EP1511526A1 (en) | 2002-05-24 | 2005-03-09 | Eli Lilly And Company | Medical syringe pump with motor driven piston |
| WO2003103750A1 (en) | 2002-06-05 | 2003-12-18 | Elan Pharma International Limited | Injector adapter and combination thereof |
| GB0214452D0 (en) | 2002-06-22 | 2002-07-31 | Liversidge Barry P | Medical needle assemblies |
| US20100160869A1 (en) | 2002-06-22 | 2010-06-24 | Barry Peter Liversidge | Medical Needle Assemblies |
| TWI314464B (en) | 2002-06-24 | 2009-09-11 | Alza Corp | Reusable, spring driven autoinjector |
| DE10229138B4 (de) | 2002-06-28 | 2008-01-31 | Tecpharma Licensing Ag | Produktausschüttvorrichtung mit Kolbenstangen-Eilrücksetzung |
| JP4598520B2 (ja) | 2002-07-02 | 2010-12-15 | パナソニック株式会社 | 医療用自動投与器具 |
| US20090280065A1 (en) | 2006-04-10 | 2009-11-12 | Willian Mary K | Uses and Compositions for Treatment of Psoriasis |
| FR2842428B1 (fr) | 2002-07-19 | 2004-10-08 | Becton Dickinson France | Dispositif d'injection d'un produit, notamment a usage medical |
| NZ598346A (en) | 2002-07-19 | 2013-10-25 | Abbvie Biotechnology Ltd | Treatment of tnf alpha related disorders |
| WO2004011065A1 (en) | 2002-07-31 | 2004-02-05 | Alza Corporation | Injection device providing automatic needle retraction |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| US20040039337A1 (en) | 2002-08-21 | 2004-02-26 | Letzing Michael Alexander | Portable safety auto-injector |
| BR0314111A (pt) | 2002-09-12 | 2005-07-26 | Childrens Hosp Medical Center | Método e dispositivo para injeção de medicação sem dor |
| CA2500195C (en) | 2002-09-24 | 2009-07-21 | Shl Medical Ab | Injecting device |
| US7699816B2 (en) | 2002-10-15 | 2010-04-20 | Tecpharma Licensing Ag | Injection device with priming stroke |
| MY150740A (en) | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
| CN1726059A (zh) | 2002-11-05 | 2006-01-25 | M2医药有限公司 | 一种一次性可穿戴的胰岛素分配装置,这种装置和一个程序控制器的组合以及控制这种装置工作的方法 |
| AU2003275893B2 (en) | 2002-11-25 | 2008-11-13 | Tecpharma Licensing Ag | Device for automatically injecting an active agent |
| JP2006507061A (ja) | 2002-11-25 | 2006-03-02 | テクファーマ・ライセンシング・アクチェンゲゼルシャフト | リセット可能な解放安全装置を有する自動注射装置 |
| WO2004047892A1 (de) | 2002-11-25 | 2004-06-10 | Tecpharma Licensing Ag | Injektionsvorrichtung mit nadelschutz |
| GB2396816A (en) | 2002-12-17 | 2004-07-07 | Pa Consulting Services | Injection device |
| GB0229345D0 (en) | 2002-12-17 | 2003-01-22 | Safe T Ltd | Hollow needle applicators |
| US6767336B1 (en) | 2003-01-09 | 2004-07-27 | Sheldon Kaplan | Automatic injector |
| AU2003303809A1 (en) | 2003-01-24 | 2004-08-23 | Alza Corporation | Collapsible syringe cartridge |
| USD494270S1 (en) | 2003-02-04 | 2004-08-10 | Sherwood Services Ag | Electrosurgical pencil with multiple scallops |
| US6932794B2 (en) | 2003-04-03 | 2005-08-23 | Becton, Dickinson And Company | Medication delivery pen |
| WO2004093029A2 (en) | 2003-04-14 | 2004-10-28 | The General Hospital Corporation | Inoculation training kit |
| US6805686B1 (en) * | 2003-05-06 | 2004-10-19 | Abbott Laboratories | Autoinjector with extendable needle protector shroud |
| US6926697B2 (en) | 2003-05-13 | 2005-08-09 | Robert Malenchek | Adaptor for converting a non-safety syringe into a safety syringe |
| GB0315600D0 (en) | 2003-07-04 | 2003-08-13 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| US7500963B2 (en) | 2003-07-22 | 2009-03-10 | Safety Syringes, Inc. | Systems and methods for automatic medical injection with safeguard |
| US20050027255A1 (en) | 2003-07-31 | 2005-02-03 | Sid Technologies, Llc | Automatic injector |
| EP1502613A1 (en) | 2003-08-01 | 2005-02-02 | Novo Nordisk A/S | Needle device with retraction means |
| DE20312677U1 (de) * | 2003-08-16 | 2004-12-23 | Schwarzbich, Jörg | Spritze mit einer Wiederverwendungssperre |
| DE10339794A1 (de) | 2003-08-28 | 2005-04-07 | Tecpharma Licensing Ag | Verabreichungsvorrichtung mit einer Schutzkappenabziehvorrichtung und einer Nadelschutzhülsenblockiereinrichtung |
| DE10340586A1 (de) | 2003-09-03 | 2005-04-07 | Tecpharma Licensing Ag | Abmischvorrichtung für Mehrkammerampulle |
| FR2860162B1 (fr) | 2003-09-26 | 2006-06-02 | Becton Dickinson France | Dispositif de protection d'un appareil d'injection |
| GB0406458D0 (en) | 2003-10-09 | 2004-04-28 | Liversidge Barry P | Safety medical needle assemblies |
| US20050085776A1 (en) | 2003-10-16 | 2005-04-21 | Edgar Hommann | Injection device for administering a fluid product |
| USD518175S1 (en) | 2003-10-31 | 2006-03-28 | Wilson-Cook Medical Inc. | Handle for medical devices, and medical device assemblies using a handle |
| US9554984B2 (en) | 2003-11-03 | 2017-01-31 | Jaleva Pharmaceuticals, Llc | Oral care compositions for topical application |
| US20050096597A1 (en) | 2003-11-03 | 2005-05-05 | Becton, Dickinson And Company | Safety shield system for a syringe |
| US7497847B2 (en) | 2003-11-03 | 2009-03-03 | Becton, Dickinson And Company | Safety shield system for a syringe |
| US7635348B2 (en) | 2003-11-04 | 2009-12-22 | Meridian Medical Technologies, Inc. | Container for medicament automatic injector and automatic injector adapted therefor |
| US20050101919A1 (en) | 2003-11-07 | 2005-05-12 | Lennart Brunnberg | Device for an injector |
| US20050115508A1 (en) | 2003-12-01 | 2005-06-02 | Little Cynthia L. | Healthy pet appropriate food and drink table |
| GB2410188B (en) | 2004-01-23 | 2006-01-25 | Medical House Plc | Injection device |
| GB0403335D0 (en) | 2004-02-14 | 2004-03-17 | Liversidge Barry P | Medical injector handling device |
| ITTO20040169A1 (it) | 2004-03-15 | 2004-06-15 | Teksid Aluminum S R L | Sistema di tenuta per recipienti ad alte pressioni ed alte temperature |
| US20050222539A1 (en) | 2004-03-30 | 2005-10-06 | Pediamed Pharmaceuticals, Inc. | Automatic injection device |
| PT1732629T (pt) | 2004-03-30 | 2019-06-07 | Lilly Co Eli | Aparelho de dispensação de medicamento com uma característica de bloqueio acionada por mola ativada por administração de dose final |
| US8372030B2 (en) | 2004-03-31 | 2013-02-12 | Cook Medical Technologies Llc | Apparatus for an improved high pressure medicinal dispenser |
| TWI439284B (zh) | 2004-04-09 | 2014-06-01 | Abbvie Biotechnology Ltd | 用於治療ＴＮＦα相關失調症之多重可變劑量療法 |
| EP3804789A1 (en) | 2004-04-29 | 2021-04-14 | AbbVie Inc. | Autoinjector with extendable needle protector shroud |
| US6976676B2 (en) * | 2004-05-10 | 2005-12-20 | Adams Troy E | Game apparatus |
| GB2414405B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414406B (en) | 2004-05-28 | 2009-03-18 | Cilag Ag Int | Injection device |
| GB2414400B (en) | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
| GB2414403B (en) | 2004-05-28 | 2009-01-07 | Cilag Ag Int | Injection device |
| GB2414404B (en) | 2004-05-28 | 2009-06-03 | Cilag Ag Int | Injection device |
| GB2414399B (en) | 2004-05-28 | 2008-12-31 | Cilag Ag Int | Injection device |
| GB2414402B (en) | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
| US20050273054A1 (en) | 2004-06-03 | 2005-12-08 | Florida Atlantic University | Epinephrine auto-injector |
| US7294119B2 (en) * | 2004-06-10 | 2007-11-13 | Safety Syringes, Inc. | Passive delivery system diluents mixing and delivery |
| US20050283162A1 (en) * | 2004-06-22 | 2005-12-22 | Stratas Byron A | Intraocular lens inserter |
| GB0414054D0 (en) | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| AU2005263180B2 (en) | 2004-07-16 | 2010-05-27 | Unitract Syringe Pty Ltd | Syringe needle sheath |
| US20060100588A1 (en) | 2004-07-23 | 2006-05-11 | Lennart Brunnberg | Needle handling device |
| US7449012B2 (en) | 2004-08-06 | 2008-11-11 | Meridian Medical Technologies, Inc. | Automatic injector |
| US20060074519A1 (en) | 2004-08-27 | 2006-04-06 | Barker Kenneth N | Medication accuracy comparison system |
| US20060047250A1 (en) | 2004-08-30 | 2006-03-02 | Hickingbotham Dyson W | Fluid delivery device |
| DE102004042581B4 (de) | 2004-09-02 | 2022-09-15 | Ypsomed Ag | Auto-Pen für Zweikammerampulle |
| US20060069350A1 (en) | 2004-09-30 | 2006-03-30 | Buenger David R | Medical syringe injector pen |
| US20060069354A1 (en) | 2004-09-30 | 2006-03-30 | Buenger David R | Syringe activation device |
| WO2006041970A2 (en) | 2004-10-08 | 2006-04-20 | Abbott Biotechnology Ltd. | Treatment of respiratory syncytial virus (rsv) infection |
| US20060089540A1 (en) | 2004-10-27 | 2006-04-27 | Alan Meissner | Device for diabetes management |
| US20060178865A1 (en) | 2004-10-29 | 2006-08-10 | Edwards D Craig | Multilingual user interface for a medical device |
| US7947017B2 (en) | 2004-11-22 | 2011-05-24 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| US7648483B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| GB2453069B (en) | 2004-11-22 | 2009-12-09 | Intelliject Llc | Devices,systems and methods for medicament delivery |
| US7648482B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems, and methods for medicament delivery |
| US8092420B2 (en) | 2004-11-24 | 2012-01-10 | Becton, Dickinson And Company | Automatic reconstitution injector device |
| US7905352B2 (en) | 2004-12-06 | 2011-03-15 | Washington Biotech Corporation | Kits containing medicine injection devices and containers |
| US20060129122A1 (en) | 2004-12-06 | 2006-06-15 | Wyrick Ronald E | Method and apparatus for delivering epinephrine |
| US8361026B2 (en) | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
| US8206360B2 (en) | 2005-02-01 | 2012-06-26 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| US7731686B2 (en) | 2005-02-01 | 2010-06-08 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
| AU2006210865B2 (en) | 2005-02-01 | 2008-12-04 | Kaleo, Inc. | Devices, systems, and methods for medicament delivery |
| US8231573B2 (en) | 2005-02-01 | 2012-07-31 | Intelliject, Inc. | Medicament delivery device having an electronic circuit system |
| US9022980B2 (en) | 2005-02-01 | 2015-05-05 | Kaleo, Inc. | Medical injector simulation device |
| US8062252B2 (en) | 2005-02-18 | 2011-11-22 | Becton, Dickinson And Company | Safety shield system for a syringe |
| US20090240210A1 (en) | 2005-03-14 | 2009-09-24 | Global Medisafe Holdings Limited | Auto retractable syringe |
| USD545439S1 (en) | 2005-04-15 | 2007-06-26 | Becton, Dickinson And Company | Blood glucose meter |
| FR2884723B1 (fr) | 2005-04-20 | 2008-03-14 | Becton Dickinson France Soc Pa | Dispositif de protection d'un dispositif d'injection |
| CN100544784C (zh) * | 2005-04-26 | 2009-09-30 | 刘文杰 | 针头回缩式注射器的筒式推杆及针头回缩可控式注射器 |
| US7694828B2 (en) | 2005-04-27 | 2010-04-13 | Biomet Manufacturing Corp. | Method and apparatus for producing autologous clotting components |
| US7905868B2 (en) | 2006-08-23 | 2011-03-15 | Medtronic Minimed, Inc. | Infusion medium delivery device and method with drive device for driving plunger in reservoir |
| KR101465456B1 (ko) | 2005-05-16 | 2014-11-27 | 애브비 바이오테크놀로지 리미티드 | 미란성 다발관절염의 치료를 위한 ｔｎｆ 억제제의 용도 |
| US20070041905A1 (en) | 2005-08-19 | 2007-02-22 | Hoffman Rebecca S | Method of treating depression using a TNF-alpha antibody |
| EP1948269A1 (en) | 2005-10-11 | 2008-07-30 | Eli Lilly And Company | Apparatus for injecting a pharmaceutical |
| TW201337266A (zh) | 2005-11-01 | 2013-09-16 | Abbott Biotech Ltd | 利用生物標記診斷關節黏連脊椎炎之方法及組合物 |
| US7682155B2 (en) | 2005-11-03 | 2010-03-23 | Meridian Medical Technologies, Inc. | Training device for an automatic injector |
| US20070161960A1 (en) | 2006-01-12 | 2007-07-12 | Fu-Yuan Li | Lancet device |
| AU2007227200B2 (en) | 2006-03-21 | 2013-01-24 | Covidien Lp | Passive latch ring safety shield for injection devices |
| GB2477046B (en) | 2006-03-29 | 2011-08-24 | Intelliject Inc | Devices,systems and methods for medicament delivery |
| SG170837A1 (en) | 2006-04-05 | 2011-05-30 | Abbott Biotech Ltd | Antibody purification |
| US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
| EP2666472A3 (en) | 2006-04-10 | 2014-04-02 | Abbott Biotechnology Ltd | Uses and compositions for treatment of psoriatic arthritis |
| US20090317399A1 (en) | 2006-04-10 | 2009-12-24 | Pollack Paul F | Uses and compositions for treatment of CROHN'S disease |
| EP2010214A4 (en) | 2006-04-10 | 2010-06-16 | Abbott Biotech Ltd | USES AND COMPOSITIONS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS |
| US20080118496A1 (en) | 2006-04-10 | 2008-05-22 | Medich John R | Uses and compositions for treatment of juvenile rheumatoid arthritis |
| EP2012586A4 (en) | 2006-04-10 | 2010-08-18 | Abbott Biotech Ltd | USES AND COMPOSITIONS FOR THE TREATMENT OF ANKYLOSANTE SPONDYLARTHRITIS |
| US20080131374A1 (en) | 2006-04-19 | 2008-06-05 | Medich John R | Uses and compositions for treatment of rheumatoid arthritis |
| US20080311043A1 (en) | 2006-06-08 | 2008-12-18 | Hoffman Rebecca S | Uses and compositions for treatment of psoriatic arthritis |
| US20100021451A1 (en) | 2006-06-08 | 2010-01-28 | Wong Robert L | Uses and compositions for treatment of ankylosing spondylitis |
| TWI498137B (zh) | 2006-06-30 | 2015-09-01 | Abbvie Biotechnology Ltd | 自動注射裝置 |
| US20100040609A1 (en) | 2006-07-07 | 2010-02-18 | Gorman James R | Methods for preventing, postponing or improving the outcome of invasive spinal procedures |
| DE102006038101A1 (de) | 2006-08-14 | 2008-02-21 | Tecpharma Licensing Ag | Injektionsvorrichtung mit Klauensicherung |
| USD629509S1 (en) | 2006-09-06 | 2010-12-21 | Abbott Biotechnology Ltd. | Automatic injection device |
| USD622374S1 (en) | 2006-09-06 | 2010-08-24 | Abbott Biotechnology Ltd. | Automatic injection device |
| MY185872A (en) | 2006-09-13 | 2021-06-14 | Abbvie Inc | Cell culture improvements |
| CN100563740C (zh) | 2006-09-28 | 2009-12-02 | 明辰股份有限公司 | 医疗药物安全注射装置及用于医疗药物注射的推杆组合件 |
| CN101616932A (zh) | 2006-10-27 | 2009-12-30 | 艾博特生物技术有限公司 | 结晶型抗-hTNFα抗体 |
| JP5680852B2 (ja) | 2006-11-21 | 2015-03-04 | カレオ，インコーポレイテッド | 薬物送達のための装置 |
| EP2125075A2 (en) | 2007-01-22 | 2009-12-02 | Intelliject, Inc. | Medical injector with compliance tracking and monitoring |
| JP5014835B2 (ja) | 2007-02-28 | 2012-08-29 | 株式会社山越 | 雨水浸透桝、及び既設雨水桝の雨水浸透桝化工法 |
| US9044378B2 (en) | 2007-05-31 | 2015-06-02 | Safety Syringes, Inc. | Anti-needle stick safety device or system for use with drugs requiring reconstitution |
| US8092998B2 (en) | 2007-05-31 | 2012-01-10 | Abbott Laboratories | Biomarkers predictive of the responsiveness to TNFα inhibitors in autoimmune disorders |
| EP2152318A4 (en) | 2007-06-01 | 2011-12-07 | Abbott Biotech Ltd | COMPOSITIONS AND USES FOR THE TREATMENT OF PSORIASIS AND CROHN'S DISEASE |
| EP2171451A4 (en) | 2007-06-11 | 2011-12-07 | Abbott Biotech Ltd | METHOD FOR TREATING JUVENILIAN IDIOPATHIC ARTHRITIS |
| CN101848733A (zh) | 2007-07-13 | 2010-09-29 | 艾博特生物技术有限公司 | 用于肺部给予TNFα抑制剂的方法和组合物 |
| RU2010107994A (ru) | 2007-08-08 | 2011-09-20 | Эбботт Лэборетриз (Us) | Композиции и способы кристаллизации антител |
| ES2742504T3 (es) | 2007-09-25 | 2020-02-14 | Becton Dickinson France | Autoinyector con elemento de eliminación de blindaje que comprende medios antimanipulación |
| JP5653217B2 (ja) | 2007-10-02 | 2015-01-14 | メディモップ メディカル プロジェクツ、エル・ティー・ディー | 外部薬剤ポンプ |
| USD619702S1 (en) | 2007-11-15 | 2010-07-13 | Tecpharma Licensing Ag | Medicine injector |
| KR20150080038A (ko) | 2007-11-30 | 2015-07-08 | 애브비 바이오테크놀로지 리미티드 | 단백질 제형 및 이의 제조방법 |
| US20090157012A1 (en) | 2007-12-13 | 2009-06-18 | University Of Victoria Innovation And Development Corporation | Syringe with extendable and retractable needle |
| CA2710333A1 (en) | 2008-01-03 | 2009-07-09 | Abbott Biotechnology Ltd. | Predicting long-term efficacy of a compound in the treatment of psoriasis |
| UA101825C2 (ru) | 2008-01-11 | 2013-05-13 | Юсб Фарма Са | Шприц (варианты), шприцевая система, цилиндр шприца, концевой колпачок для защиты иглы шприца и система доставки лекарственного вещества |
| BRPI0906490A2 (pt) | 2008-01-15 | 2015-07-14 | Abbott Lab | Vetores de expressão de mamífero melhorados e uso dos mesmos |
| CA2711984A1 (en) | 2008-01-15 | 2009-07-23 | Abbott Gmbh & Co. Kg | Powdered protein compositions and methods of making same |
| MX2010010503A (es) | 2008-03-24 | 2010-11-09 | Abbott Biotech Ltd | Metodos y composiciones para tratar perdida osea. |
| MX337305B (es) | 2008-05-12 | 2016-02-24 | Kaleo Inc | Dispositivo de administracion de medicamentos provisto de un sistema de circuitos electronicos. |
| US8021344B2 (en) | 2008-07-28 | 2011-09-20 | Intelliject, Inc. | Medicament delivery device configured to produce an audible output |
| BRPI0913189A2 (pt) | 2008-05-30 | 2016-01-12 | Allergan Inc | dispositivo de injeção para cargas de aumento de tecido mole, agentes bioativos e outros materiais biocompatíveis em forma líquida ou gel |
| US8069097B2 (en) | 2008-06-05 | 2011-11-29 | Harris Corporation | Media inventory service |
| US8900197B2 (en) | 2008-06-20 | 2014-12-02 | West Pharmaceutical Services, Inc. | Automatic injection mechanism with frontal buttress |
| JP5161712B2 (ja) | 2008-09-03 | 2013-03-13 | キヤノン株式会社 | 撮像装置、及び撮像方法 |
| BRPI0918297A2 (pt) | 2008-09-10 | 2016-05-03 | Hoffmann La Roche | "dispositivo de distribuição de droga para bombear a medicação para dentro do corpo de um usuário" |
| USD641077S1 (en) | 2008-09-15 | 2011-07-05 | Sanofi-Aventis Deutschland Gmbh | Medical injector |
| EP2180459A1 (en) | 2008-10-24 | 2010-04-28 | Sanofi-Aventis Deutschland GmbH | Device for simulating the operation of a medication delivery device |
| GB2465389A (en) | 2008-11-17 | 2010-05-19 | Owen Mumford Ltd | Syringe needle cover remover |
| USD655060S1 (en) | 2009-03-23 | 2012-02-28 | Karl Storz Gmbh & Co. Kg | Cleaning adapter |
| USD621932S1 (en) | 2009-03-23 | 2010-08-17 | Karl Storz Gmbh & Co. Kg | Videolaparoscope |
| RU2524487C2 (ru) | 2009-04-29 | 2014-07-27 | Эббви Байотекнолоджи Лтд | Автоматическое инъекционное устройство |
| CN104490767A (zh) | 2009-05-04 | 2015-04-08 | 艾伯维生物技术有限公司 | 人抗TNF-α抗体的稳定高蛋白质浓度制剂 |
| EP2255842B2 (en) | 2009-05-26 | 2023-05-24 | SHL Medical AG | Needle cover assembly |
| US8641671B2 (en) | 2009-07-30 | 2014-02-04 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
| CA2769102C (en) | 2009-07-31 | 2017-09-19 | 3M Innovative Properties Company | Hollow microneedle arrays |
| USD633199S1 (en) | 2009-10-05 | 2011-02-22 | Pyng Medical Corp. | Insertion tool for bone portals |
| US8758301B2 (en) | 2009-12-15 | 2014-06-24 | Abbvie Biotechnology Ltd | Firing button for automatic injection device |
| CA2789168A1 (en) | 2010-02-02 | 2011-08-11 | Abbott Biotechnology Ltd. | Methods and compositions for predicting responsiveness to treatment with tnf-.alpha. inhibitor |
| EP2361648A1 (en) | 2010-02-18 | 2011-08-31 | Sanofi-Aventis Deutschland GmbH | Remover for a protective needle shield |
| RU2573042C2 (ru) | 2010-04-21 | 2016-01-20 | Эббви Байотекнолоджи Лтд. | Носимое устройство для автоматической инъекции для управляемой подачи терапевтических агентов |
| USD645139S1 (en) | 2010-05-11 | 2011-09-13 | Discus Dental, Llc | Dental composite syringe |
| HUE039740T2 (hu) | 2010-06-03 | 2019-01-28 | Abbvie Biotechnology Ltd | Alkalmazások és készítmények hidradenitis suppurativa (HS) kezelésére |
| USD638935S1 (en) | 2010-06-25 | 2011-05-31 | Abbott Cardiovascular Systems Inc. | Medical device handle |
| USD650070S1 (en) | 2010-09-16 | 2011-12-06 | Panasonic Corporation | Injector |
| USD647613S1 (en) | 2010-12-30 | 2011-10-25 | Kimberly-Clark, Inc. | Ergonomic handle for medical device |
| BR112013018905B1 (pt) | 2011-01-24 | 2021-07-13 | Abbvie Biotechnology Ltd | Dispositivos de injeção automática que têm superfícies de pega sobremoldadas. |
| USD677380S1 (en) | 2011-01-24 | 2013-03-05 | Abbvie Biotechnology Ltd. | Automatic injection device |
| AU2012210170B2 (en) | 2011-01-24 | 2016-09-29 | Elcam Medical Agricultural Cooperative Association Ltd. | Injector |
| BR112013018773A2 (pt) | 2011-01-24 | 2016-10-25 | Abbvie Biotechnology Ltd | remoção de proteções de agulha de seringas e dispositivos de injeção automática |
| CN103608053B (zh) | 2011-03-18 | 2016-06-22 | 艾伯维公司 | 用于组装自动注射装置及其子组件的系统、装置和方法 |
| CA2831563A1 (en) | 2011-03-29 | 2012-10-04 | Abbvie Inc. | Improved shroud deployment in automatic injection devices |
| USD653329S1 (en) | 2011-05-11 | 2012-01-31 | Femasys Inc. | Device for relieving fluid pressure |
| SG11201405200PA (en) | 2012-03-02 | 2014-09-26 | Abbvie Inc | Automatic injection training device |
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