JP5758878B2 - ヒアルロン酸の精製方法 - Google Patents

ヒアルロン酸の精製方法 Download PDF

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Publication number
JP5758878B2
JP5758878B2 JP2012505379A JP2012505379A JP5758878B2 JP 5758878 B2 JP5758878 B2 JP 5758878B2 JP 2012505379 A JP2012505379 A JP 2012505379A JP 2012505379 A JP2012505379 A JP 2012505379A JP 5758878 B2 JP5758878 B2 JP 5758878B2
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Prior art keywords
activated carbon
hyaluronic acid
purification
stirring
cooling
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JP2012505379A
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Japanese (ja)
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JPWO2011114472A1 (ja
Inventor
昌信 香坂
昌信 香坂
克己 石毛
克己 石毛
和利 日置
和利 日置
強志 辻
強志 辻
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Denka Co Ltd
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Denki Kagaku Kogyo KK
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Publication of JPWO2011114472A1 publication Critical patent/JPWO2011114472A1/ja
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
JP2012505379A 2010-03-17 2010-03-17 ヒアルロン酸の精製方法 Active JP5758878B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2010/054595 WO2011114472A1 (ja) 2010-03-17 2010-03-17 ヒアルロン酸の精製方法

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JPWO2011114472A1 JPWO2011114472A1 (ja) 2013-06-27
JP5758878B2 true JP5758878B2 (ja) 2015-08-05

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JP2012505379A Active JP5758878B2 (ja) 2010-03-17 2010-03-17 ヒアルロン酸の精製方法

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JP (1) JP5758878B2 (zh)
KR (1) KR101627014B1 (zh)
CN (1) CN102803298B (zh)
TW (1) TWI549970B (zh)
WO (1) WO2011114472A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105899544B (zh) * 2014-01-14 2019-09-20 丘比株式会社 透明质酸和/或其盐及其制造方法、以及包含该透明质酸和/或其盐的食品、化妆品和药品

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62501471A (ja) * 1985-01-18 1987-06-18 バイオ−テクノロジ−・ジエネラル・コ−ポレイシヨン 連鎖球菌の発酵による高分子量ヒアルロン酸ナトリウムの製造方法
JPS63270701A (ja) * 1987-04-30 1988-11-08 Nippon Kayaku Co Ltd ヒアルロン酸の精製法
JP2009242522A (ja) * 2008-03-31 2009-10-22 Mitsubishi Rayon Co Ltd ヒアルロン酸およびその塩の製造方法
JP2009256463A (ja) * 2008-04-16 2009-11-05 Mitsubishi Rayon Co Ltd ヒアルロン酸の精製方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6312293A (ja) 1986-07-03 1988-01-19 Kyowa Hakko Kogyo Co Ltd ヒアルロン酸の精製法
JP2728542B2 (ja) 1990-05-07 1998-03-18 株式会社日立製作所 同時2軸延伸装置のリンク過負荷検出装置
BRPI0713215A2 (pt) * 2006-07-06 2012-04-17 Realince Life Sciences Pvt Ltd processo eficiente de produção e purificação de ácido hialurÈnico de elevado peso molecular e produto resultante
KR101509139B1 (ko) * 2006-11-23 2015-04-08 주식회사 엘지생명과학 히알루론산의 정제방법
CN101935362B (zh) * 2009-06-30 2012-07-25 上海佰加壹医药有限公司 预铺助滤剂纯化透明质酸的方法
WO2013132506A1 (en) * 2012-03-07 2013-09-12 Praj Industries Limited Process for the purification of hyaluronic acid salts (ha) from fermentation broth

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62501471A (ja) * 1985-01-18 1987-06-18 バイオ−テクノロジ−・ジエネラル・コ−ポレイシヨン 連鎖球菌の発酵による高分子量ヒアルロン酸ナトリウムの製造方法
JPS63270701A (ja) * 1987-04-30 1988-11-08 Nippon Kayaku Co Ltd ヒアルロン酸の精製法
JP2009242522A (ja) * 2008-03-31 2009-10-22 Mitsubishi Rayon Co Ltd ヒアルロン酸およびその塩の製造方法
JP2009256463A (ja) * 2008-04-16 2009-11-05 Mitsubishi Rayon Co Ltd ヒアルロン酸の精製方法

Also Published As

Publication number Publication date
KR20130056223A (ko) 2013-05-29
WO2011114472A1 (ja) 2011-09-22
TWI549970B (zh) 2016-09-21
TW201139464A (en) 2011-11-16
CN102803298B (zh) 2015-09-23
KR101627014B1 (ko) 2016-06-03
CN102803298A (zh) 2012-11-28
JPWO2011114472A1 (ja) 2013-06-27

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