JP5592792B2 - 二重特異性抗体の融合体 - Google Patents
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Landscapes
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| GB0718834.5 | 2007-09-26 | ||
| PCT/GB2008/003331 WO2009040562A1 (en) | 2007-09-26 | 2008-09-26 | Dual specificity antibody fusions |
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| AT503889B1 (de) | 2006-07-05 | 2011-12-15 | Star Biotechnologische Forschungs Und Entwicklungsges M B H F | Multivalente immunglobuline |
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| EP2014680A1 (en) | 2007-07-10 | 2009-01-14 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Recombinant, single-chain, trivalent tri-specific or bi-specific antibody derivatives |
| CA2694488A1 (en) | 2007-07-31 | 2009-02-05 | Medimmune, Llc | Multispecific epitope binding proteins and uses thereof |
| ES2628395T3 (es) | 2007-08-15 | 2017-08-02 | Bayer Pharma Aktiengesellschaft | Anticuerpo regulado por proteasa |
| EP2195341B1 (en) | 2007-09-26 | 2017-03-22 | UCB Biopharma SPRL | Dual specificity antibody fusions |
| EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| MX2010005783A (es) | 2007-11-27 | 2010-08-10 | Ablynx Nv | Secuencias de aminoacidos dirigidas contra citoquinas heterodimericas y/o sus receptores y polipeptidos que comprenden las mismas. |
| EA023031B1 (ru) | 2007-11-30 | 2016-04-29 | Глаксо Груп Лимитед | Антиген-связывающая конструкция и ее применение |
| US8227577B2 (en) | 2007-12-21 | 2012-07-24 | Hoffman-La Roche Inc. | Bivalent, bispecific antibodies |
| CA2737241C (en) * | 2008-09-26 | 2017-08-29 | Ucb Pharma S.A. | Multivalent antibody fusion proteins |
| JP2012510821A (ja) | 2008-12-04 | 2012-05-17 | アボット・ラボラトリーズ | 二重可変ドメイン免疫グロブリンおよびその使用 |
| BRPI1007602A2 (pt) | 2009-05-27 | 2016-02-16 | Hoffmann La Roche | "anticorpo tri ou tetraespecífico, método para preparação de um anticorpo triespecífico ou tetraespecífico, célula hospedeira, composição, composição farmacêutica e método para o tratamento de um paciente com necessidade de terapia" |
| WO2011030107A1 (en) | 2009-09-10 | 2011-03-17 | Ucb Pharma S.A. | Multivalent antibodies |
| GB201005063D0 (en) | 2010-03-25 | 2010-05-12 | Ucb Pharma Sa | Biological products |
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| Publication number | Publication date |
|---|---|
| CA2700714A1 (en) | 2009-04-02 |
| CN101842387B (zh) | 2014-05-07 |
| CN101842387A (zh) | 2010-09-22 |
| ES2667729T3 (es) | 2018-05-14 |
| CN104004088A (zh) | 2014-08-27 |
| US8629246B2 (en) | 2014-01-14 |
| US20140194596A1 (en) | 2014-07-10 |
| US20100239582A1 (en) | 2010-09-23 |
| EP2535350B1 (en) | 2018-01-24 |
| CA2700714C (en) | 2018-09-11 |
| CN104004088B (zh) | 2017-11-07 |
| US10100130B2 (en) | 2018-10-16 |
| JP2015002744A (ja) | 2015-01-08 |
| EP2195341B1 (en) | 2017-03-22 |
| US11427650B2 (en) | 2022-08-30 |
| ES2622460T3 (es) | 2017-07-06 |
| JP6106640B2 (ja) | 2017-04-05 |
| US20190127489A1 (en) | 2019-05-02 |
| EP2535349A1 (en) | 2012-12-19 |
| WO2009040562A1 (en) | 2009-04-02 |
| US20160311930A1 (en) | 2016-10-27 |
| EP2535350A1 (en) | 2012-12-19 |
| US9309327B2 (en) | 2016-04-12 |
| EP2535351A3 (en) | 2013-04-03 |
| EP2195341A1 (en) | 2010-06-16 |
| EP2535351A2 (en) | 2012-12-19 |
| US20180118853A1 (en) | 2018-05-03 |
| JP2010539921A (ja) | 2010-12-24 |
| US9828438B2 (en) | 2017-11-28 |
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