JP5236628B2 - １１−β−ヒドロキシステロイドデヒドロゲナーゼ１阻害剤としての、シクロヘキシルイミダゾールラクタム誘導体 - Google Patents

１１−β−ヒドロキシステロイドデヒドロゲナーゼ１阻害剤としての、シクロヘキシルイミダゾールラクタム誘導体 Download PDF

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JP5236628B2
JP5236628B2 JP2009506760A JP2009506760A JP5236628B2 JP 5236628 B2 JP5236628 B2 JP 5236628B2 JP 2009506760 A JP2009506760 A JP 2009506760A JP 2009506760 A JP2009506760 A JP 2009506760A JP 5236628 B2 JP5236628 B2 JP 5236628B2
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tetrahydro
dichloro
pyrrolidin
benzimidazol
ylmethyl
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JP2009534412A (ja
JP2009534412A5 (enExample
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レベッカ・リン・グエンザー
トーマス・エドワード・マブリー
アシュラフ・サイード
ナンシー・ジューン・スナイダー
オーウェン・ブレンダン・ウォレス
ヤンピン・シュ
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イーライ リリー アンド カンパニー
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

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JP2009506760A 2006-04-21 2007-04-19 １１−β−ヒドロキシステロイドデヒドロゲナーゼ１阻害剤としての、シクロヘキシルイミダゾールラクタム誘導体 Expired - Fee Related JP5236628B2 (ja)

Applications Claiming Priority (3)

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US74532106P 2006-04-21 2006-04-21
US60/745,321 2006-04-21
PCT/US2007/066907 WO2007124329A1 (en) 2006-04-21 2007-04-19 Cyclohexylimidazole lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

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JP2009534412A JP2009534412A (ja) 2009-09-24
JP2009534412A5 JP2009534412A5 (enExample) 2011-01-13
JP5236628B2 true JP5236628B2 (ja) 2013-07-17

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US (1) US7820659B2 (enExample)
EP (1) EP2029576B1 (enExample)
JP (1) JP5236628B2 (enExample)
CN (1) CN101426780B (enExample)
AU (1) AU2007240450B2 (enExample)
BR (1) BRPI0710273A2 (enExample)
CA (1) CA2646678C (enExample)
EA (1) EA014717B1 (enExample)
ES (1) ES2422165T3 (enExample)
MX (1) MX2008013328A (enExample)
WO (1) WO2007124329A1 (enExample)

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EP2029576A1 (en) 2009-03-04
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CA2646678C (en) 2014-02-11
AU2007240450B2 (en) 2011-12-22
EA200870461A1 (ru) 2009-04-28
ES2422165T3 (es) 2013-09-09
AU2007240450A1 (en) 2007-11-01
EP2029576B1 (en) 2013-06-19
CN101426780A (zh) 2009-05-06
CN101426780B (zh) 2013-06-26
CA2646678A1 (en) 2007-11-01
MX2008013328A (es) 2008-10-27
WO2007124329A1 (en) 2007-11-01
US20090088428A1 (en) 2009-04-02
BRPI0710273A2 (pt) 2011-08-09

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