JP4755742B2 - 医薬最終処方物におけるナノディスパージョンの使用 - Google Patents
医薬最終処方物におけるナノディスパージョンの使用 Download PDFInfo
- Publication number
- JP4755742B2 JP4755742B2 JP12999099A JP12999099A JP4755742B2 JP 4755742 B2 JP4755742 B2 JP 4755742B2 JP 12999099 A JP12999099 A JP 12999099A JP 12999099 A JP12999099 A JP 12999099A JP 4755742 B2 JP4755742 B2 JP 4755742B2
- Authority
- JP
- Japan
- Prior art keywords
- polyoxyethylene
- nanodispersion
- nano
- fatty acid
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98810422.0 | 1998-05-11 | ||
| EP98810422 | 1998-05-11 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11335266A JPH11335266A (ja) | 1999-12-07 |
| JPH11335266A5 JPH11335266A5 (https=) | 2006-06-22 |
| JP4755742B2 true JP4755742B2 (ja) | 2011-08-24 |
Family
ID=8236078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12999099A Expired - Lifetime JP4755742B2 (ja) | 1998-05-11 | 1999-05-11 | 医薬最終処方物におけるナノディスパージョンの使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7081253B2 (https=) |
| EP (1) | EP0956853B1 (https=) |
| JP (1) | JP4755742B2 (https=) |
| KR (1) | KR100622285B1 (https=) |
| CN (1) | CN1220483C (https=) |
| AR (1) | AR019274A1 (https=) |
| AT (1) | ATE312597T1 (https=) |
| AU (1) | AU767896B2 (https=) |
| BR (1) | BRPI9902068B8 (https=) |
| CZ (1) | CZ166999A3 (https=) |
| DE (1) | DE59912910D1 (https=) |
| ES (1) | ES2253871T3 (https=) |
| HU (1) | HUP9901570A2 (https=) |
| ID (1) | ID22565A (https=) |
| MY (1) | MY133019A (https=) |
| PL (1) | PL332934A1 (https=) |
| RU (1) | RU2224505C2 (https=) |
| SG (1) | SG71923A1 (https=) |
| TW (1) | TWI241915B (https=) |
| ZA (1) | ZA993200B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230270691A1 (en) * | 2020-06-01 | 2023-08-31 | Advent Therapeutics, Inc. | Pharmaceutical compositions comprising insoluble active ingredients |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9908309D0 (en) * | 1999-04-12 | 1999-06-02 | Phares Pharm Res Nv | Lipid aggregate forming compositions and their use |
| FR2805761B1 (fr) * | 2000-03-02 | 2002-08-30 | Mainelab | Nanocapsules lipidiques, procede de preparation et utilisation comme medicament |
| TW586945B (en) * | 2001-01-12 | 2004-05-11 | Novartis Ag | Lens care product containing dexpanthenol |
| US20030113366A1 (en) * | 2001-12-14 | 2003-06-19 | Macgregor Alexander | Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents |
| RU2200558C1 (ru) * | 2002-04-23 | 2003-03-20 | Нестерук Владимир Викторович | Лекарственное средство, содержащее финастерид |
| AT6609U3 (de) * | 2003-04-07 | 2004-04-26 | Unipack Ges M B H Abfuell Und | Verfahren zum herstellen einer klaren lecithin enthaltenden oralen zubereitung |
| ITMI20032019A1 (it) * | 2003-10-17 | 2005-04-18 | Fidia Farmaceutici | Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono |
| WO2005117830A1 (en) * | 2004-06-04 | 2005-12-15 | Camurus Ab | Liquid depot formulations |
| TWI350183B (en) * | 2003-12-31 | 2011-10-11 | Ind Tech Res Inst | A liposome and a preparation method |
| US20060198891A1 (en) * | 2004-11-29 | 2006-09-07 | Francois Ravenelle | Solid formulations of liquid biologically active agents |
| DE112006001898B4 (de) * | 2005-07-21 | 2013-05-08 | National Institute For Materials Science | Vorrichtung zur Inhalation von Arzneimitteln |
| US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
| US7745400B2 (en) | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
| NZ572601A (en) | 2006-03-29 | 2012-03-30 | Univ Wayne State | Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery |
| JP4840031B2 (ja) | 2006-08-31 | 2011-12-21 | ソニー株式会社 | ナビゲーション装置、ナビゲーション処理方法及びナビゲーション処理プログラム |
| GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
| EP1938801A1 (en) * | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
| CL2008000037A1 (es) * | 2007-01-16 | 2008-10-10 | Bayer Consumer Care Ag | Solucion coloidal que comprende al menos un ingrediente activo, al menos una molecula formadora de membrana y al menos un componente espumante; procedimiento para fabricar la solucion coloidal; y su uso para tratar trastornos dermatologicos. |
| WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
| WO2008135855A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
| US9545384B2 (en) | 2007-06-04 | 2017-01-17 | Bend Research, Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate |
| EP2162120B1 (en) | 2007-06-04 | 2016-05-04 | Bend Research, Inc | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
| US9233078B2 (en) | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
| WO2009073215A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
| CN100536826C (zh) * | 2007-12-28 | 2009-09-09 | 清华大学 | 一种绵羊油纳米乳液及其制备方法和应用 |
| US20110033545A1 (en) * | 2009-08-06 | 2011-02-10 | Absize, Inc. | Topical pharmaceutical preparations having both a nanoparticle solution and a nanoparticle suspension and methods for the treatment of acute and chronic pain therewith |
| FR2949063B1 (fr) * | 2009-08-11 | 2011-09-30 | Pf Medicament | Composition pharmaceutique comprenant un ester de dha destinee a etre administree par voie parenterale |
| DE202010004750U1 (de) | 2010-04-09 | 2011-10-11 | Biofrontera Bioscience Gmbh | Pharmazeutische oder/und kosmetische Zusammensetzung zur Behandlung der Haut |
| CN102277748A (zh) * | 2010-06-12 | 2011-12-14 | 罗莱家纺股份有限公司 | 纳米维生素微胶囊整理剂的使用方法 |
| KR101494594B1 (ko) * | 2011-08-30 | 2015-02-23 | 주식회사 종근당 | 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| KR101586791B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | GnRH 유도체의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| KR101586790B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | 음이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| KR101586789B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | 양이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| EP3583954A1 (en) * | 2018-06-19 | 2019-12-25 | neubourg skin care GmbH | Nanodispersions of birch bark extract, electrospun fibers containing such nanodispersions and their use for the treatment of wounds |
| EP4065108B1 (en) | 2019-11-25 | 2025-08-06 | The Johns Hopkins University | Formulations of terameprocol and temozolomide and their use in stimulation of humoral immunity in tumors |
| CN111388744B (zh) * | 2020-01-15 | 2021-05-18 | 华中科技大学 | 一种凝胶贮库及其制法与制备术后止血制剂的应用 |
| CA3170810A1 (en) * | 2020-02-11 | 2021-08-19 | Advent Therapeutics Inc. | Compositions of vitamin a palmitate, processes for their preparation, uses and methods comprising them |
| US20230310386A1 (en) * | 2020-05-20 | 2023-10-05 | Intervet Inc. | Injectable pharmaceutical compositions and uses thereof |
| MX2022016437A (es) | 2020-06-30 | 2023-01-30 | Chong Kun Dang Pharmaceutical Corp | Composicion inyectable que comprende un analogo de gnrh. |
| WO2024165166A1 (en) | 2023-02-10 | 2024-08-15 | Tetra Pharm Technologies | A cannabinoid-based o/w emulsification system for oral administration targeting endocannabinoid receptors |
| WO2024208434A1 (en) | 2023-04-06 | 2024-10-10 | Biofrontera Bioscience Gmbh | Pressurized nanoemulsion |
| WO2024208433A1 (en) | 2023-04-06 | 2024-10-10 | Biofrontera Bioscience Gmbh | Nanoemulsion without propylene glycol |
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| DE3150990A1 (de) | 1981-12-23 | 1983-06-30 | A. Nattermann & Cie GmbH, 5000 Köln | Neue pflanzenschutzmittelsuspensionskonzentrate |
| US4675193A (en) * | 1983-10-31 | 1987-06-23 | Borden, Inc. | Cheese-flavored substance and method of producing same |
| US4816247A (en) * | 1985-09-11 | 1989-03-28 | American Cyanamid Company | Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs |
| US4965357A (en) | 1986-08-07 | 1990-10-23 | Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | 2,5,6-substituted N1 -alkylpyrimidines |
| DE3852409T2 (de) | 1987-01-27 | 1995-04-20 | Vestar Inc | Aus Phospholipiden bestehende Darreichungsform für wasserunlösliche Wirksubstanzen. |
| DE68917544T2 (de) | 1988-06-20 | 1994-12-15 | Shiseido Co Ltd | Durchsichtiges Präparat. |
| CA1337397C (en) * | 1988-09-29 | 1995-10-24 | Hideo Nakajima | Emulsified composition |
| FR2648462B1 (fr) | 1989-06-15 | 1994-01-28 | Oreal | Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede |
| CH677886A5 (https=) * | 1989-06-26 | 1991-07-15 | Hans Georg Prof Dr Weder | |
| JP2785981B2 (ja) * | 1989-11-20 | 1998-08-13 | 株式会社資生堂 | 乳化組成物 |
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| US5688761A (en) * | 1991-04-19 | 1997-11-18 | Lds Technologies, Inc. | Convertible microemulsion formulations |
| ZA925581B (en) * | 1991-07-26 | 1993-05-14 | Smithkline Beecham Corp | Pharmaceutical microemulsions. |
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| CH685674A5 (de) | 1993-12-19 | 1995-09-15 | Marigen Sa | Ultramikroemulsionen aus spontan dispergierbaren Konzentraten mit pharmakologisch wirksamen Estern von Apocarotinolen. |
| ES2094688B1 (es) * | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| PE52896A1 (es) * | 1994-10-26 | 1996-12-12 | Novartis Ag | Composicion farmaceutica |
| EP0711557A1 (de) | 1994-11-09 | 1996-05-15 | Ciba-Geigy Ag | Pharmazeutische Formulierungsgrundlage |
| EP0733358A3 (de) * | 1995-03-21 | 1998-05-20 | Novartis AG | Intravenös applizierbare Nanosuspensionen |
| WO1996037192A1 (en) * | 1995-05-26 | 1996-11-28 | Vesifact Ag | Pharmaceutical and cosmetic compositions containing sphingo- and glycolipids |
| DE19522693A1 (de) | 1995-06-22 | 1997-01-02 | Dianorm G Maierhofer Gmbh | Zusammensetzung zur Herstellung feindisperser Systeme und Verfahren zu ihrer Herstellung |
| JP3508314B2 (ja) * | 1995-08-18 | 2004-03-22 | 大正製薬株式会社 | ビタミンcを配合した液剤 |
| AU7689996A (en) * | 1995-12-12 | 1997-07-03 | Vesifact Ag | Cortisone spray for topical administration |
| US6245349B1 (en) * | 1996-02-23 | 2001-06-12 | éLAN CORPORATION PLC | Drug delivery compositions suitable for intravenous injection |
| DE59710082D1 (de) * | 1996-12-13 | 2003-06-18 | Vesifact Ag Baar | Kosmetische Präparate in Form einer Nanodispersion |
| US6028067A (en) * | 1997-12-05 | 2000-02-22 | Chong Kun Dang Corp. | Cyclosporin-containing microemulsion preconcentrate composition |
-
1999
- 1999-04-19 TW TW088106257A patent/TWI241915B/zh not_active IP Right Cessation
- 1999-04-23 MY MYPI99001603A patent/MY133019A/en unknown
- 1999-05-04 AT AT99810383T patent/ATE312597T1/de not_active IP Right Cessation
- 1999-05-04 DE DE59912910T patent/DE59912910D1/de not_active Expired - Lifetime
- 1999-05-04 PL PL99332934A patent/PL332934A1/xx unknown
- 1999-05-04 EP EP99810383A patent/EP0956853B1/de not_active Expired - Lifetime
- 1999-05-04 ES ES99810383T patent/ES2253871T3/es not_active Expired - Lifetime
- 1999-05-05 SG SG1999002127A patent/SG71923A1/en unknown
- 1999-05-06 US US09/306,006 patent/US7081253B2/en not_active Expired - Lifetime
- 1999-05-06 ID IDP990417A patent/ID22565A/id unknown
- 1999-05-07 AR ARP990102160A patent/AR019274A1/es active IP Right Grant
- 1999-05-10 BR BRPI9902068A patent/BRPI9902068B8/pt not_active IP Right Cessation
- 1999-05-10 CN CNB991063686A patent/CN1220483C/zh not_active Expired - Lifetime
- 1999-05-10 AU AU28050/99A patent/AU767896B2/en not_active Ceased
- 1999-05-10 KR KR1019990016580A patent/KR100622285B1/ko not_active Expired - Fee Related
- 1999-05-10 CZ CZ991669A patent/CZ166999A3/cs unknown
- 1999-05-10 ZA ZA9903200A patent/ZA993200B/xx unknown
- 1999-05-11 RU RU99109958/15A patent/RU2224505C2/ru not_active IP Right Cessation
- 1999-05-11 JP JP12999099A patent/JP4755742B2/ja not_active Expired - Lifetime
- 1999-05-11 HU HU9901570A patent/HUP9901570A2/hu unknown
-
2006
- 2006-06-05 US US11/446,844 patent/US7871642B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230270691A1 (en) * | 2020-06-01 | 2023-08-31 | Advent Therapeutics, Inc. | Pharmaceutical compositions comprising insoluble active ingredients |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0956853B1 (de) | 2005-12-14 |
| EP0956853A2 (de) | 1999-11-17 |
| AU2805099A (en) | 1999-11-18 |
| PL332934A1 (en) | 1999-11-22 |
| US7081253B2 (en) | 2006-07-25 |
| ID22565A (id) | 1999-11-11 |
| JPH11335266A (ja) | 1999-12-07 |
| HU9901570D0 (en) | 1999-07-28 |
| SG71923A1 (en) | 2000-04-18 |
| CN1235017A (zh) | 1999-11-17 |
| US7871642B2 (en) | 2011-01-18 |
| ATE312597T1 (de) | 2005-12-15 |
| RU2224505C2 (ru) | 2004-02-27 |
| BRPI9902068B8 (pt) | 2021-05-25 |
| MY133019A (en) | 2007-10-31 |
| TWI241915B (en) | 2005-10-21 |
| CZ166999A3 (cs) | 1999-11-17 |
| BR9902068A (pt) | 2000-06-06 |
| CN1220483C (zh) | 2005-09-28 |
| KR19990088156A (ko) | 1999-12-27 |
| EP0956853A3 (de) | 2000-01-05 |
| KR100622285B1 (ko) | 2006-09-11 |
| DE59912910D1 (de) | 2006-01-19 |
| AR019274A1 (es) | 2002-02-13 |
| AU767896B2 (en) | 2003-11-27 |
| BR9902068B1 (pt) | 2014-10-29 |
| US20060292191A1 (en) | 2006-12-28 |
| ZA993200B (en) | 1999-11-11 |
| ES2253871T3 (es) | 2006-06-01 |
| US20030190347A1 (en) | 2003-10-09 |
| HUP9901570A2 (hu) | 2001-06-28 |
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