KR100622285B1 - 나노분산액을 사용한 약제학적 최종 제형의 제조 방법, 나노분산액의 예비상 및 나노분산액 - Google Patents
나노분산액을 사용한 약제학적 최종 제형의 제조 방법, 나노분산액의 예비상 및 나노분산액 Download PDFInfo
- Publication number
- KR100622285B1 KR100622285B1 KR1019990016580A KR19990016580A KR100622285B1 KR 100622285 B1 KR100622285 B1 KR 100622285B1 KR 1019990016580 A KR1019990016580 A KR 1019990016580A KR 19990016580 A KR19990016580 A KR 19990016580A KR 100622285 B1 KR100622285 B1 KR 100622285B1
- Authority
- KR
- South Korea
- Prior art keywords
- polyethoxylated
- delete delete
- nanodispersion
- nanodispersions
- components
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98810422.0 | 1998-05-11 | ||
| EP98810422 | 1998-05-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR19990088156A KR19990088156A (ko) | 1999-12-27 |
| KR100622285B1 true KR100622285B1 (ko) | 2006-09-11 |
Family
ID=8236078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019990016580A Expired - Fee Related KR100622285B1 (ko) | 1998-05-11 | 1999-05-10 | 나노분산액을 사용한 약제학적 최종 제형의 제조 방법, 나노분산액의 예비상 및 나노분산액 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7081253B2 (https=) |
| EP (1) | EP0956853B1 (https=) |
| JP (1) | JP4755742B2 (https=) |
| KR (1) | KR100622285B1 (https=) |
| CN (1) | CN1220483C (https=) |
| AR (1) | AR019274A1 (https=) |
| AT (1) | ATE312597T1 (https=) |
| AU (1) | AU767896B2 (https=) |
| BR (1) | BRPI9902068B8 (https=) |
| CZ (1) | CZ166999A3 (https=) |
| DE (1) | DE59912910D1 (https=) |
| ES (1) | ES2253871T3 (https=) |
| HU (1) | HUP9901570A2 (https=) |
| ID (1) | ID22565A (https=) |
| MY (1) | MY133019A (https=) |
| PL (1) | PL332934A1 (https=) |
| RU (1) | RU2224505C2 (https=) |
| SG (1) | SG71923A1 (https=) |
| TW (1) | TWI241915B (https=) |
| ZA (1) | ZA993200B (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9908309D0 (en) * | 1999-04-12 | 1999-06-02 | Phares Pharm Res Nv | Lipid aggregate forming compositions and their use |
| FR2805761B1 (fr) * | 2000-03-02 | 2002-08-30 | Mainelab | Nanocapsules lipidiques, procede de preparation et utilisation comme medicament |
| TW586945B (en) * | 2001-01-12 | 2004-05-11 | Novartis Ag | Lens care product containing dexpanthenol |
| US20030113366A1 (en) * | 2001-12-14 | 2003-06-19 | Macgregor Alexander | Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents |
| RU2200558C1 (ru) * | 2002-04-23 | 2003-03-20 | Нестерук Владимир Викторович | Лекарственное средство, содержащее финастерид |
| AT6609U3 (de) * | 2003-04-07 | 2004-04-26 | Unipack Ges M B H Abfuell Und | Verfahren zum herstellen einer klaren lecithin enthaltenden oralen zubereitung |
| ITMI20032019A1 (it) * | 2003-10-17 | 2005-04-18 | Fidia Farmaceutici | Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono |
| WO2005117830A1 (en) * | 2004-06-04 | 2005-12-15 | Camurus Ab | Liquid depot formulations |
| TWI350183B (en) * | 2003-12-31 | 2011-10-11 | Ind Tech Res Inst | A liposome and a preparation method |
| US20060198891A1 (en) * | 2004-11-29 | 2006-09-07 | Francois Ravenelle | Solid formulations of liquid biologically active agents |
| DE112006001898B4 (de) * | 2005-07-21 | 2013-05-08 | National Institute For Materials Science | Vorrichtung zur Inhalation von Arzneimitteln |
| US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
| US7745400B2 (en) | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
| NZ572601A (en) | 2006-03-29 | 2012-03-30 | Univ Wayne State | Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery |
| JP4840031B2 (ja) | 2006-08-31 | 2011-12-21 | ソニー株式会社 | ナビゲーション装置、ナビゲーション処理方法及びナビゲーション処理プログラム |
| GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
| EP1938801A1 (en) * | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
| CL2008000037A1 (es) * | 2007-01-16 | 2008-10-10 | Bayer Consumer Care Ag | Solucion coloidal que comprende al menos un ingrediente activo, al menos una molecula formadora de membrana y al menos un componente espumante; procedimiento para fabricar la solucion coloidal; y su uso para tratar trastornos dermatologicos. |
| WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
| WO2008135855A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
| US9545384B2 (en) | 2007-06-04 | 2017-01-17 | Bend Research, Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate |
| EP2162120B1 (en) | 2007-06-04 | 2016-05-04 | Bend Research, Inc | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
| US9233078B2 (en) | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
| WO2009073215A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
| CN100536826C (zh) * | 2007-12-28 | 2009-09-09 | 清华大学 | 一种绵羊油纳米乳液及其制备方法和应用 |
| US20110033545A1 (en) * | 2009-08-06 | 2011-02-10 | Absize, Inc. | Topical pharmaceutical preparations having both a nanoparticle solution and a nanoparticle suspension and methods for the treatment of acute and chronic pain therewith |
| FR2949063B1 (fr) * | 2009-08-11 | 2011-09-30 | Pf Medicament | Composition pharmaceutique comprenant un ester de dha destinee a etre administree par voie parenterale |
| DE202010004750U1 (de) | 2010-04-09 | 2011-10-11 | Biofrontera Bioscience Gmbh | Pharmazeutische oder/und kosmetische Zusammensetzung zur Behandlung der Haut |
| CN102277748A (zh) * | 2010-06-12 | 2011-12-14 | 罗莱家纺股份有限公司 | 纳米维生素微胶囊整理剂的使用方法 |
| KR101494594B1 (ko) * | 2011-08-30 | 2015-02-23 | 주식회사 종근당 | 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| KR101586791B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | GnRH 유도체의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| KR101586790B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | 음이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| KR101586789B1 (ko) | 2012-12-28 | 2016-01-19 | 주식회사 종근당 | 양이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물 |
| EP3583954A1 (en) * | 2018-06-19 | 2019-12-25 | neubourg skin care GmbH | Nanodispersions of birch bark extract, electrospun fibers containing such nanodispersions and their use for the treatment of wounds |
| EP4065108B1 (en) | 2019-11-25 | 2025-08-06 | The Johns Hopkins University | Formulations of terameprocol and temozolomide and their use in stimulation of humoral immunity in tumors |
| CN111388744B (zh) * | 2020-01-15 | 2021-05-18 | 华中科技大学 | 一种凝胶贮库及其制法与制备术后止血制剂的应用 |
| CA3170810A1 (en) * | 2020-02-11 | 2021-08-19 | Advent Therapeutics Inc. | Compositions of vitamin a palmitate, processes for their preparation, uses and methods comprising them |
| US20230310386A1 (en) * | 2020-05-20 | 2023-10-05 | Intervet Inc. | Injectable pharmaceutical compositions and uses thereof |
| CA3185481A1 (en) * | 2020-06-01 | 2021-12-09 | Advent Therapeutics, Inc. | Pharmaceutical compositions comprising insoluble active ingredients |
| MX2022016437A (es) | 2020-06-30 | 2023-01-30 | Chong Kun Dang Pharmaceutical Corp | Composicion inyectable que comprende un analogo de gnrh. |
| WO2024165166A1 (en) | 2023-02-10 | 2024-08-15 | Tetra Pharm Technologies | A cannabinoid-based o/w emulsification system for oral administration targeting endocannabinoid receptors |
| WO2024208434A1 (en) | 2023-04-06 | 2024-10-10 | Biofrontera Bioscience Gmbh | Pressurized nanoemulsion |
| WO2024208433A1 (en) | 2023-04-06 | 2024-10-10 | Biofrontera Bioscience Gmbh | Nanoemulsion without propylene glycol |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR960016908A (ko) * | 1994-11-09 | 1996-06-17 | 베르너 발데크 | 제약학상 담체 |
| KR960033470A (ko) * | 1995-03-21 | 1996-10-22 | 베르너 발데크 | 정맥내 투여용 나노현탁액 |
| US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3150990A1 (de) | 1981-12-23 | 1983-06-30 | A. Nattermann & Cie GmbH, 5000 Köln | Neue pflanzenschutzmittelsuspensionskonzentrate |
| US4675193A (en) * | 1983-10-31 | 1987-06-23 | Borden, Inc. | Cheese-flavored substance and method of producing same |
| US4816247A (en) * | 1985-09-11 | 1989-03-28 | American Cyanamid Company | Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs |
| US4965357A (en) | 1986-08-07 | 1990-10-23 | Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg | 2,5,6-substituted N1 -alkylpyrimidines |
| DE3852409T2 (de) | 1987-01-27 | 1995-04-20 | Vestar Inc | Aus Phospholipiden bestehende Darreichungsform für wasserunlösliche Wirksubstanzen. |
| DE68917544T2 (de) | 1988-06-20 | 1994-12-15 | Shiseido Co Ltd | Durchsichtiges Präparat. |
| CA1337397C (en) * | 1988-09-29 | 1995-10-24 | Hideo Nakajima | Emulsified composition |
| FR2648462B1 (fr) | 1989-06-15 | 1994-01-28 | Oreal | Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede |
| CH677886A5 (https=) * | 1989-06-26 | 1991-07-15 | Hans Georg Prof Dr Weder | |
| JP2785981B2 (ja) * | 1989-11-20 | 1998-08-13 | 株式会社資生堂 | 乳化組成物 |
| AU668509B2 (en) * | 1991-04-19 | 1996-05-09 | Affinity Biotech, Inc. | Convertible microemulsion formulations |
| US5688761A (en) * | 1991-04-19 | 1997-11-18 | Lds Technologies, Inc. | Convertible microemulsion formulations |
| ZA925581B (en) * | 1991-07-26 | 1993-05-14 | Smithkline Beecham Corp | Pharmaceutical microemulsions. |
| US5260065A (en) | 1991-09-17 | 1993-11-09 | Micro Vesicular Systems, Inc. | Blended lipid vesicles |
| IL101007A (en) * | 1992-02-18 | 1997-08-14 | Pharmos Ltd | Dry stable compositions prepared by lyophilization |
| IL101387A (en) | 1992-03-26 | 1999-11-30 | Pharmos Ltd | Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets |
| CH685674A5 (de) | 1993-12-19 | 1995-09-15 | Marigen Sa | Ultramikroemulsionen aus spontan dispergierbaren Konzentraten mit pharmakologisch wirksamen Estern von Apocarotinolen. |
| ES2094688B1 (es) * | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| PE52896A1 (es) * | 1994-10-26 | 1996-12-12 | Novartis Ag | Composicion farmaceutica |
| WO1996037192A1 (en) * | 1995-05-26 | 1996-11-28 | Vesifact Ag | Pharmaceutical and cosmetic compositions containing sphingo- and glycolipids |
| DE19522693A1 (de) | 1995-06-22 | 1997-01-02 | Dianorm G Maierhofer Gmbh | Zusammensetzung zur Herstellung feindisperser Systeme und Verfahren zu ihrer Herstellung |
| JP3508314B2 (ja) * | 1995-08-18 | 2004-03-22 | 大正製薬株式会社 | ビタミンcを配合した液剤 |
| AU7689996A (en) * | 1995-12-12 | 1997-07-03 | Vesifact Ag | Cortisone spray for topical administration |
| US6245349B1 (en) * | 1996-02-23 | 2001-06-12 | éLAN CORPORATION PLC | Drug delivery compositions suitable for intravenous injection |
| DE59710082D1 (de) * | 1996-12-13 | 2003-06-18 | Vesifact Ag Baar | Kosmetische Präparate in Form einer Nanodispersion |
| US6028067A (en) * | 1997-12-05 | 2000-02-22 | Chong Kun Dang Corp. | Cyclosporin-containing microemulsion preconcentrate composition |
-
1999
- 1999-04-19 TW TW088106257A patent/TWI241915B/zh not_active IP Right Cessation
- 1999-04-23 MY MYPI99001603A patent/MY133019A/en unknown
- 1999-05-04 AT AT99810383T patent/ATE312597T1/de not_active IP Right Cessation
- 1999-05-04 DE DE59912910T patent/DE59912910D1/de not_active Expired - Lifetime
- 1999-05-04 PL PL99332934A patent/PL332934A1/xx unknown
- 1999-05-04 EP EP99810383A patent/EP0956853B1/de not_active Expired - Lifetime
- 1999-05-04 ES ES99810383T patent/ES2253871T3/es not_active Expired - Lifetime
- 1999-05-05 SG SG1999002127A patent/SG71923A1/en unknown
- 1999-05-06 US US09/306,006 patent/US7081253B2/en not_active Expired - Lifetime
- 1999-05-06 ID IDP990417A patent/ID22565A/id unknown
- 1999-05-07 AR ARP990102160A patent/AR019274A1/es active IP Right Grant
- 1999-05-10 BR BRPI9902068A patent/BRPI9902068B8/pt not_active IP Right Cessation
- 1999-05-10 CN CNB991063686A patent/CN1220483C/zh not_active Expired - Lifetime
- 1999-05-10 AU AU28050/99A patent/AU767896B2/en not_active Ceased
- 1999-05-10 KR KR1019990016580A patent/KR100622285B1/ko not_active Expired - Fee Related
- 1999-05-10 CZ CZ991669A patent/CZ166999A3/cs unknown
- 1999-05-10 ZA ZA9903200A patent/ZA993200B/xx unknown
- 1999-05-11 RU RU99109958/15A patent/RU2224505C2/ru not_active IP Right Cessation
- 1999-05-11 JP JP12999099A patent/JP4755742B2/ja not_active Expired - Lifetime
- 1999-05-11 HU HU9901570A patent/HUP9901570A2/hu unknown
-
2006
- 2006-06-05 US US11/446,844 patent/US7871642B2/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
| KR960016908A (ko) * | 1994-11-09 | 1996-06-17 | 베르너 발데크 | 제약학상 담체 |
| US5658898A (en) * | 1994-11-09 | 1997-08-19 | Ciba Geigy Corporation | Intravenous solutions for a derivative of staurosporine |
| KR960033470A (ko) * | 1995-03-21 | 1996-10-22 | 베르너 발데크 | 정맥내 투여용 나노현탁액 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0956853B1 (de) | 2005-12-14 |
| EP0956853A2 (de) | 1999-11-17 |
| AU2805099A (en) | 1999-11-18 |
| PL332934A1 (en) | 1999-11-22 |
| US7081253B2 (en) | 2006-07-25 |
| JP4755742B2 (ja) | 2011-08-24 |
| ID22565A (id) | 1999-11-11 |
| JPH11335266A (ja) | 1999-12-07 |
| HU9901570D0 (en) | 1999-07-28 |
| SG71923A1 (en) | 2000-04-18 |
| CN1235017A (zh) | 1999-11-17 |
| US7871642B2 (en) | 2011-01-18 |
| ATE312597T1 (de) | 2005-12-15 |
| RU2224505C2 (ru) | 2004-02-27 |
| BRPI9902068B8 (pt) | 2021-05-25 |
| MY133019A (en) | 2007-10-31 |
| TWI241915B (en) | 2005-10-21 |
| CZ166999A3 (cs) | 1999-11-17 |
| BR9902068A (pt) | 2000-06-06 |
| CN1220483C (zh) | 2005-09-28 |
| KR19990088156A (ko) | 1999-12-27 |
| EP0956853A3 (de) | 2000-01-05 |
| DE59912910D1 (de) | 2006-01-19 |
| AR019274A1 (es) | 2002-02-13 |
| AU767896B2 (en) | 2003-11-27 |
| BR9902068B1 (pt) | 2014-10-29 |
| US20060292191A1 (en) | 2006-12-28 |
| ZA993200B (en) | 1999-11-11 |
| ES2253871T3 (es) | 2006-06-01 |
| US20030190347A1 (en) | 2003-10-09 |
| HUP9901570A2 (hu) | 2001-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100622285B1 (ko) | 나노분산액을 사용한 약제학적 최종 제형의 제조 방법, 나노분산액의 예비상 및 나노분산액 | |
| US5726164A (en) | Nanosuspensions for intravenous administration | |
| US5658898A (en) | Intravenous solutions for a derivative of staurosporine | |
| US6479540B1 (en) | Compositions of tocol-soluble therapeutics | |
| DE69935602T2 (de) | Verabreichungssyteme für proteinarzneistoffe unter verwendung von membranmimetika | |
| JP3202999B2 (ja) | 肝移行性リポソーム製剤 | |
| WO1999044594A1 (fr) | Emulsions huileuses destinees a etre administrees par inhalation | |
| JPH02203A (ja) | 薬物担体 | |
| JP2688235B2 (ja) | 医薬物質含有脂肪乳剤の用時調製型キットおよび医薬物質含有脂肪乳剤の調製方法 | |
| JPH0145446B2 (https=) | ||
| DE60101370T2 (de) | Pharmazeutische zusammensetzungen, die terbinafin enthalten | |
| HU201873B (en) | Process for producing lipide micromedium containing ibudilaste | |
| EP1256337A1 (de) | Verfahren und Zusammensetzungen zum Aufbringen eines Wirkstoffs auf ein Substrat | |
| TWI911987B (zh) | 含有傳明酸與維a酸的複方組合物 | |
| MXPA99004334A (es) | Uso de nanodispersiones en formulaciones farmaceuticas finales | |
| EP0467838A2 (de) | Verfahren zur Herstellung einer injizierbaren Liposomendispersion | |
| JPS61221114A (ja) | 脂肪乳剤 | |
| JP2616240B2 (ja) | 脂肪乳剤の製法 | |
| WO2002009670A1 (en) | Liquid or semi-solid pharmaceutical excipient and pharmaceutical composition comprising the same | |
| MXPA96001033A (en) | Nanosuspensions for intraven administration | |
| JPWO1999044594A1 (ja) | 吸入投与用脂肪乳剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
St.27 status event code: A-0-1-A10-A12-nap-PA0109 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| D13-X000 | Search requested |
St.27 status event code: A-1-2-D10-D13-srh-X000 |
|
| D14-X000 | Search report completed |
St.27 status event code: A-1-2-D10-D14-srh-X000 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U11-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 6 |
|
| FPAY | Annual fee payment |
Payment date: 20120904 Year of fee payment: 7 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 7 |
|
| FPAY | Annual fee payment |
Payment date: 20130829 Year of fee payment: 8 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 8 |
|
| FPAY | Annual fee payment |
Payment date: 20140901 Year of fee payment: 9 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 9 |
|
| FPAY | Annual fee payment |
Payment date: 20150730 Year of fee payment: 10 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 10 |
|
| FPAY | Annual fee payment |
Payment date: 20160818 Year of fee payment: 11 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 11 |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20170905 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
|
| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20170905 |