HUP9901570A2 - Nanodiszperziók alkalmazása gyógyszerkészítményekben - Google Patents

Nanodiszperziók alkalmazása gyógyszerkészítményekben

Info

Publication number
HUP9901570A2
HUP9901570A2 HU9901570A HUP9901570A HUP9901570A2 HU P9901570 A2 HUP9901570 A2 HU P9901570A2 HU 9901570 A HU9901570 A HU 9901570A HU P9901570 A HUP9901570 A HU P9901570A HU P9901570 A2 HUP9901570 A2 HU P9901570A2
Authority
HU
Hungary
Prior art keywords
nanodispersions
pharmaceutical compositions
pharmaceutical preparations
pharmaceutical
ananodispersion
Prior art date
Application number
HU9901570A
Other languages
English (en)
Inventor
Dietmar Hüglin
Joachim Friedrich Röding
Andreas Werner Supersaxo
Hans Georg Weder
Original Assignee
Ciba Specialty Chemicals Holding Inc.
Vesifact Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Specialty Chemicals Holding Inc., Vesifact Ag. filed Critical Ciba Specialty Chemicals Holding Inc.
Publication of HU9901570D0 publication Critical patent/HU9901570D0/hu
Publication of HUP9901570A2 publication Critical patent/HUP9901570A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya nanodiszperziók alkalmazásagyógyszerkészítményekben, az ilyen nanodiszperziókat tartalmazógyógyszerkészítmények, és ezek különböző gyógyászati alkalmazásai. Ananodiszperzió egy membránképző vegyületet, egy koemulgeátort és egylipofil komponenst tartalmaz, előállítására (a) a fenti komponensekethomogén, tiszta folyadékká (úgynevezett nanodiszperziós előfázis)keverik össze, majd (b) az (a) lépésben kapott folyadékot hozzáadják agyógyszerkészítmény vizes fázisához; és mindkét lépést kiegészítőenergiaforrások alkalmazása nélkül hajtják végre. Ó
HU9901570A 1998-05-11 1999-05-11 Nanodiszperziók alkalmazása gyógyszerkészítményekben HUP9901570A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98810422 1998-05-11

Publications (2)

Publication Number Publication Date
HU9901570D0 HU9901570D0 (en) 1999-07-28
HUP9901570A2 true HUP9901570A2 (hu) 2001-06-28

Family

ID=8236078

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901570A HUP9901570A2 (hu) 1998-05-11 1999-05-11 Nanodiszperziók alkalmazása gyógyszerkészítményekben

Country Status (20)

Country Link
US (2) US7081253B2 (hu)
EP (1) EP0956853B1 (hu)
JP (1) JP4755742B2 (hu)
KR (1) KR100622285B1 (hu)
CN (1) CN1220483C (hu)
AR (1) AR019274A1 (hu)
AT (1) ATE312597T1 (hu)
AU (1) AU767896B2 (hu)
BR (1) BRPI9902068B8 (hu)
CZ (1) CZ166999A3 (hu)
DE (1) DE59912910D1 (hu)
ES (1) ES2253871T3 (hu)
HU (1) HUP9901570A2 (hu)
ID (1) ID22565A (hu)
MY (1) MY133019A (hu)
PL (1) PL332934A1 (hu)
RU (1) RU2224505C2 (hu)
SG (1) SG71923A1 (hu)
TW (1) TWI241915B (hu)
ZA (1) ZA993200B (hu)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9908309D0 (en) * 1999-04-12 1999-06-02 Phares Pharm Res Nv Lipid aggregate forming compositions and their use
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
MY128762A (en) * 2001-01-12 2007-02-28 Novartis Ag Lens care product containing dexpanthenol
US20030113366A1 (en) * 2001-12-14 2003-06-19 Macgregor Alexander Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
AT6609U3 (de) * 2003-04-07 2004-04-26 Unipack Ges M B H Abfuell Und Verfahren zum herstellen einer klaren lecithin enthaltenden oralen zubereitung
ITMI20032019A1 (it) * 2003-10-17 2005-04-18 Fidia Farmaceutici Microemulsioni di retinoidi e composizioni farmaceutiche che le contengono
TWI350183B (en) * 2003-12-31 2011-10-11 Ind Tech Res Inst A liposome and a preparation method
KR101225257B1 (ko) * 2004-06-04 2013-01-22 카무러스 에이비 유동성 데포 제제
US20060198891A1 (en) * 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
US20090107495A1 (en) * 2005-07-21 2009-04-30 National Institute For Materials Science Device for inhalation of medicine
US7745400B2 (en) 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
AU2007233155B2 (en) 2006-03-29 2012-04-26 Scitech Development Llc Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
JP4840031B2 (ja) 2006-08-31 2011-12-21 ソニー株式会社 ナビゲーション装置、ナビゲーション処理方法及びナビゲーション処理プログラム
EP1938801A1 (en) * 2006-12-22 2008-07-02 Biofrontera Bioscience GmbH Nanoemulsion
CL2008000037A1 (es) * 2007-01-16 2008-10-10 Bayer Consumer Care Ag Solucion coloidal que comprende al menos un ingrediente activo, al menos una molecula formadora de membrana y al menos un componente espumante; procedimiento para fabricar la solucion coloidal; y su uso para tratar trastornos dermatologicos.
WO2008135855A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
US8309129B2 (en) 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
US9724362B2 (en) 2007-12-06 2017-08-08 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
EP2240162A4 (en) 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
CN100536826C (zh) * 2007-12-28 2009-09-09 清华大学 一种绵羊油纳米乳液及其制备方法和应用
US20110033545A1 (en) * 2009-08-06 2011-02-10 Absize, Inc. Topical pharmaceutical preparations having both a nanoparticle solution and a nanoparticle suspension and methods for the treatment of acute and chronic pain therewith
FR2949063B1 (fr) * 2009-08-11 2011-09-30 Pf Medicament Composition pharmaceutique comprenant un ester de dha destinee a etre administree par voie parenterale
DE202010004750U1 (de) 2010-04-09 2011-10-11 Biofrontera Bioscience Gmbh Pharmazeutische oder/und kosmetische Zusammensetzung zur Behandlung der Haut
CN102277748A (zh) * 2010-06-12 2011-12-14 罗莱家纺股份有限公司 纳米维生素微胶囊整理剂的使用方法
KR101494594B1 (ko) 2011-08-30 2015-02-23 주식회사 종근당 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
KR101586789B1 (ko) 2012-12-28 2016-01-19 주식회사 종근당 양이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
KR101586790B1 (ko) 2012-12-28 2016-01-19 주식회사 종근당 음이온성 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
KR101586791B1 (ko) 2012-12-28 2016-01-19 주식회사 종근당 ＧｎＲＨ 유도체의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
EP3583954A1 (en) * 2018-06-19 2019-12-25 neubourg skin care GmbH Nanodispersions of birch bark extract, electrospun fibers containing such nanodispersions and their use for the treatment of wounds
CN111388744B (zh) * 2020-01-15 2021-05-18 华中科技大学 一种凝胶贮库及其制法与制备术后止血制剂的应用
US20230248801A1 (en) 2020-06-30 2023-08-10 Chong Kun Dang Pharmaceutical Corp. INJECTABLE COMPOSITION COMPRISING GnRH ANALOGUE

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3150990A1 (de) 1981-12-23 1983-06-30 A. Nattermann & Cie GmbH, 5000 Köln Neue pflanzenschutzmittelsuspensionskonzentrate
US4675193A (en) * 1983-10-31 1987-06-23 Borden, Inc. Cheese-flavored substance and method of producing same
US4816247A (en) * 1985-09-11 1989-03-28 American Cyanamid Company Emulsion compositions for administration of sparingly water soluble ionizable hydrophobic drugs
EP0262344B1 (de) 1986-08-07 1996-03-27 MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG N-alkylierte quartäre stickstoffhaltige Heterozyklen, Verfahren zu deren Herstellung und deren Verwendung in Arzneimitteln
ES2068197T3 (es) 1987-01-27 1995-04-16 Vestar Inc Vehiculo de liberacion a base de fosfolipidos para ingredientes activos insolubles en agua.
DE68917544T2 (de) 1988-06-20 1994-12-15 Shiseido Co Ltd Durchsichtiges Präparat.
US5338761A (en) * 1988-09-29 1994-08-16 Shiseido Company Ltd. Emulsified composition
FR2648462B1 (fr) * 1989-06-15 1994-01-28 Oreal Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede
JP2785981B2 (ja) * 1989-11-20 1998-08-13 株式会社資生堂 乳化組成物
DK0580778T3 (da) * 1991-04-19 2000-01-31 Lds Technologies Inc Konvertible mikroemulsionsformuleringer
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
DE69214652T2 (de) * 1991-07-26 1997-03-20 Smithkline Beecham Corp W/o mikroemulsionen
US5260065A (en) 1991-09-17 1993-11-09 Micro Vesicular Systems, Inc. Blended lipid vesicles
IL101007A (en) * 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
IL101387A (en) 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
CH685674A5 (de) 1993-12-19 1995-09-15 Marigen Sa Ultramikroemulsionen aus spontan dispergierbaren Konzentraten mit pharmakologisch wirksamen Estern von Apocarotinolen.
MY129435A (en) * 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
EP0711557A1 (de) * 1994-11-09 1996-05-15 Ciba-Geigy Ag Pharmazeutische Formulierungsgrundlage
EP0733358A3 (de) * 1995-03-21 1998-05-20 Novartis AG Intravenös applizierbare Nanosuspensionen
WO1996037192A1 (en) * 1995-05-26 1996-11-28 Vesifact Ag Pharmaceutical and cosmetic compositions containing sphingo- and glycolipids
DE19522693A1 (de) 1995-06-22 1997-01-02 Dianorm G Maierhofer Gmbh Zusammensetzung zur Herstellung feindisperser Systeme und Verfahren zu ihrer Herstellung
JP3508314B2 (ja) * 1995-08-18 2004-03-22 大正製薬株式会社 ビタミンｃを配合した液剤
AU7689996A (en) * 1995-12-12 1997-07-03 Vesifact Ag Cortisone spray for topical administration
US6245349B1 (en) * 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
ATE240088T1 (de) * 1996-12-13 2003-05-15 Vesifact Ag Kosmetische präparate in form einer nanodispersion
US6028067A (en) * 1997-12-05 2000-02-22 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition

Also Published As

Publication number Publication date
CZ166999A3 (cs) 1999-11-17
ES2253871T3 (es) 2006-06-01
RU2224505C2 (ru) 2004-02-27
AU767896B2 (en) 2003-11-27
TWI241915B (en) 2005-10-21
BRPI9902068B8 (pt) 2021-05-25
HU9901570D0 (en) 1999-07-28
ATE312597T1 (de) 2005-12-15
EP0956853A2 (de) 1999-11-17
ZA993200B (en) 1999-11-11
CN1220483C (zh) 2005-09-28
MY133019A (en) 2007-10-31
ID22565A (id) 1999-11-11
JPH11335266A (ja) 1999-12-07
DE59912910D1 (de) 2006-01-19
SG71923A1 (en) 2000-04-18
JP4755742B2 (ja) 2011-08-24
AU2805099A (en) 1999-11-18
KR19990088156A (ko) 1999-12-27
US7081253B2 (en) 2006-07-25
BR9902068A (pt) 2000-06-06
EP0956853B1 (de) 2005-12-14
BR9902068B1 (pt) 2014-10-29
US20060292191A1 (en) 2006-12-28
KR100622285B1 (ko) 2006-09-11
PL332934A1 (en) 1999-11-22
CN1235017A (zh) 1999-11-17
EP0956853A3 (de) 2000-01-05
US20030190347A1 (en) 2003-10-09
US7871642B2 (en) 2011-01-18
AR019274A1 (es) 2002-02-13

Similar Documents

Publication Publication Date Title
HUP9901570A2 (hu) Nanodiszperziók alkalmazása gyógyszerkészítményekben
HUP9901572A2 (hu) Nanodiszperziók alkalmazása kozmetikai készítményekben
ES2157993T3 (es) Benzoilguanidinas, su preparacion y su uso en medicamentos.
NO20003698D0 (no) Orale sammensetninger
DK67783D0 (da) Pulverformig blanding omfattende amphifile lipidbestanddele og eventuelt hydrofobe bestanddele, fremgangsmade til fremstilling af samme, hydratiserede, lagdelte lipidfaser, fremgangsmade til fremstilling heraf samt kosmetisk sammensaetning
HUP0302797A2 (hu) Eljárás nem kristályos atorvasztatin-kalcium előállítására
FI960012A (fi) Vedellinen, monifaasinen, stabiili valmisformulaatti kasvinsuojelussa käytettäviä vaikuttavia aineita varten ja menetelmiä sen valmistamiseksi
BR0005936A (pt) Liberação de produtos farmacêuticos instáveis
HUP0303182A2 (hu) Gyógyászati készítmények
DK0695171T3 (da) Lyosfærer indeholdende gonadotropin
RS50495B (sr) Postupak za pripremanje preparata u obliku praha
HUP0302060A2 (hu) Eljárás készítmények elżállítására
HUP0102521A2 (hu) Sztilbénszármazékot és platina koordinációs vegyületet tartalmazó daganatellenes szer
ATE224717T1 (de) Oral anzuwendende arzneizubereitungen enthaltend eine benzhydrylpiperazine und eine zyklodextrin
HUP0104489A2 (hu) Stabilizált makrolidek és ezeket tartalmazó gyógyászati készítmények
AU7665287A (en) Pharmaceutical preparations
DK1264602T3 (da) Farmaceutiske præparater
DK0399903T3 (da) Præparater på basis af imipramin
ES2140565T3 (es) Nuevos derivados de pirazina-carboxamida, su preparacion y su utilizacion en medicamentos.
FI954579A (fi) Uusia pednisolonijohdannaisia
ES2191174T3 (es) (-)hidroxicitrato de magnesio, procedimiento de preparacion, aplicaciones y composiciones principalmente farmaceuticas que lo contienen.
HUP0300653A2 (hu) Herbicid hatóanyagot tartalmazó folyékony készítmények előállítása és alkalmazása
DK1054686T3 (da) Farmaceutisk formulering af en didemninforbindelse
DK164161C (da) Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater
DK0885208T3 (da) Taxoider, fremstilling af disse forbindelser og farmaceutiske præparater indeholdende disse forbindelser

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees