JP4729269B2 - レーザ走査型顕微鏡 - Google Patents

レーザ走査型顕微鏡 Download PDF

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Publication number
JP4729269B2
JP4729269B2 JP2004163360A JP2004163360A JP4729269B2 JP 4729269 B2 JP4729269 B2 JP 4729269B2 JP 2004163360 A JP2004163360 A JP 2004163360A JP 2004163360 A JP2004163360 A JP 2004163360A JP 4729269 B2 JP4729269 B2 JP 4729269B2
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Japan
Prior art keywords
laser
laser light
wavelength
microscope
deviation
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Expired - Fee Related
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JP2004163360A
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English (en)
Japanese (ja)
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JP2005345614A5 (https=
JP2005345614A (ja
Inventor
牧男 上野
昭典 顕谷
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Olympus Corp
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Olympus Corp
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Application filed by Olympus Corp filed Critical Olympus Corp
Priority to JP2004163360A priority Critical patent/JP4729269B2/ja
Priority to US11/141,517 priority patent/US7342219B2/en
Publication of JP2005345614A publication Critical patent/JP2005345614A/ja
Publication of JP2005345614A5 publication Critical patent/JP2005345614A5/ja
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B26/00—Optical devices or arrangements for the control of light using movable or deformable optical elements
    • G02B26/08—Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
    • G02B26/10—Scanning systems
    • G02B26/101—Scanning systems with both horizontal and vertical deflecting means, e.g. raster or XY scanners
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
    • G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
    • G02F1/01—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour 
    • G02F1/11—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour  based on acousto-optical elements, e.g. using variable diffraction by sound or like mechanical waves
    • G—PHYSICS
    • G02—OPTICS
    • G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
    • G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
    • G02F1/29—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the position or the direction of light beams, i.e. deflection
    • G02F1/33—Acousto-optical deflection devices
    • G—PHYSICS
    • G02—OPTICS
    • G02F—OPTICAL DEVICES OR ARRANGEMENTS FOR THE CONTROL OF LIGHT BY MODIFICATION OF THE OPTICAL PROPERTIES OF THE MEDIA OF THE ELEMENTS INVOLVED THEREIN; NON-LINEAR OPTICS; FREQUENCY-CHANGING OF LIGHT; OPTICAL LOGIC ELEMENTS; OPTICAL ANALOGUE/DIGITAL CONVERTERS
    • G02F1/00—Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics
    • G02F1/35—Non-linear optics
    • G02F1/365—Non-linear optics in an optical waveguide structure

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  • Physics & Mathematics (AREA)
  • Nonlinear Science (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microscoopes, Condenser (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
JP2004163360A 2004-06-01 2004-06-01 レーザ走査型顕微鏡 Expired - Fee Related JP4729269B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2004163360A JP4729269B2 (ja) 2004-06-01 2004-06-01 レーザ走査型顕微鏡
US11/141,517 US7342219B2 (en) 2004-06-01 2005-05-31 Laser scanning microscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004163360A JP4729269B2 (ja) 2004-06-01 2004-06-01 レーザ走査型顕微鏡

Publications (3)

Publication Number Publication Date
JP2005345614A JP2005345614A (ja) 2005-12-15
JP2005345614A5 JP2005345614A5 (https=) 2007-07-12
JP4729269B2 true JP4729269B2 (ja) 2011-07-20

Family

ID=35424154

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004163360A Expired - Fee Related JP4729269B2 (ja) 2004-06-01 2004-06-01 レーザ走査型顕微鏡

Country Status (2)

Country Link
US (1) US7342219B2 (https=)
JP (1) JP4729269B2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2827180A1 (en) 2013-06-24 2015-01-21 Olympus Corporation Scanning optical microscope

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JP4518549B2 (ja) * 2004-08-20 2010-08-04 正樹 小林 蛍光断層画像計測装置
JP4869734B2 (ja) * 2005-04-25 2012-02-08 オリンパス株式会社 多光子励起走査型レーザ顕微鏡
EP1862838B1 (en) * 2006-05-29 2009-08-19 Olympus Corporation Laser scanning microscope and microscopic observing method
GB0617945D0 (en) 2006-09-12 2006-10-18 Ucl Business Plc Imaging apparatus and methods
US7551359B2 (en) * 2006-09-14 2009-06-23 3M Innovative Properties Company Beam splitter apparatus and system
EP1959292A3 (en) * 2007-02-13 2009-06-17 Olympus Corporation Laser microscope
JP5058625B2 (ja) * 2007-02-19 2012-10-24 オリンパス株式会社 レーザ顕微鏡
JP5058624B2 (ja) * 2007-02-19 2012-10-24 オリンパス株式会社 レーザ顕微鏡
US7936503B2 (en) * 2007-02-19 2011-05-03 Olympus Corporation Laser scanning microscope
JP5307439B2 (ja) * 2007-04-23 2013-10-02 オリンパス株式会社 レーザ顕微鏡
JP4928351B2 (ja) * 2007-05-25 2012-05-09 オリンパス株式会社 顕微鏡
GB0900526D0 (en) * 2009-01-14 2009-02-11 Perkinelmer Ltd Fluorescence microscopy methods and apparatus
TWI594828B (zh) * 2009-05-28 2017-08-11 伊雷克托科學工業股份有限公司 應用於雷射處理工件中的特徵的聲光偏轉器及相關雷射處理方法
WO2011052248A1 (en) * 2009-11-02 2011-05-05 Olympus Corporation Beam splitter apparatus, light source apparatus, and scanning observation apparatus
EP3151052B1 (en) 2010-02-01 2025-03-26 Illumina, Inc. Focusing methods and optical systems and assemblies using the same
GB201006679D0 (en) 2010-04-21 2010-06-09 Ucl Business Plc Methods and apparatus to control acousto-optic deflectors
US9494781B2 (en) * 2011-01-19 2016-11-15 California Institute Of Technology Plane-projection multi-photon microscopy
JP5616824B2 (ja) * 2011-03-10 2014-10-29 オリンパス株式会社 顕微鏡装置
JP5620319B2 (ja) 2011-03-23 2014-11-05 オリンパス株式会社 顕微鏡
GB201106787D0 (en) 2011-04-20 2011-06-01 Ucl Business Plc Methods and apparatus to control acousto-optic deflectors
US9095414B2 (en) * 2011-06-24 2015-08-04 The Regents Of The University Of California Nonlinear optical photodynamic therapy (NLO-PDT) of the cornea
US9200887B2 (en) * 2012-10-12 2015-12-01 Thorlabs, Inc. Compact, low dispersion, and low aberration adaptive optics scanning system
JP6257312B2 (ja) * 2013-12-24 2018-01-10 オリンパス株式会社 顕微鏡システム
US10423017B2 (en) 2014-10-15 2019-09-24 Inserm (Institut National De La Sante Et De La Recherche Medicale) Method for determining the characteristics of a system for generating a spatial light modulation in phase and amplitude at high refresh rate
KR102309213B1 (ko) * 2015-03-06 2021-10-05 인텔 코포레이션 레이저 빔 조향용 음향 광학 편향기 및 거울
US10754223B2 (en) 2016-11-03 2020-08-25 Harris Corporation Multi-channel laser system including an acoustic-optic modulator (AOM) with atom trap and related methods
US11506877B2 (en) 2016-11-10 2022-11-22 The Trustees Of Columbia University In The City Of New York Imaging instrument having objective axis and light sheet or light beam projector axis intersecting at less than 90 degrees
EP3540500B1 (en) * 2018-03-12 2021-04-07 Harris Corporation Multi-channel phase-capable acousto-optic modulator (aom) including beam stabilizer and related methods
JP7013066B2 (ja) * 2019-06-07 2022-01-31 インスペック株式会社 キャリブレーションシステム及び描画装置
GB2632850A (en) * 2023-08-24 2025-02-26 Renishaw Plc Spectrometer, module and method

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63170608A (ja) * 1987-01-09 1988-07-14 Olympus Optical Co Ltd 走査型レ−ザ−顕微鏡
JPH06302491A (ja) * 1993-04-15 1994-10-28 Nikon Corp 露光量制御装置
US6166385A (en) 1995-09-19 2000-12-26 Cornell Research Foundation, Inc. Multi-photon laser microscopy
JPH10246876A (ja) * 1997-03-06 1998-09-14 Asahi Optical Co Ltd レーザー変調光学系
JPH11125792A (ja) * 1997-10-21 1999-05-11 Canon Inc 投・受光装置
JPH11202212A (ja) * 1998-01-13 1999-07-30 Nikon Corp 顕微鏡
JPH11296922A (ja) * 1998-04-07 1999-10-29 Sony Corp 露光装置及び露光方法
DE19827139C2 (de) * 1998-06-18 2002-01-31 Zeiss Carl Jena Gmbh Mikroskop mit einem über eine Lichtleitfaser eingekoppelten Kurzpulslaser
JP4576664B2 (ja) * 2000-03-08 2010-11-10 株式会社ニコン 光路ズレ検知装置、および共焦点顕微鏡
JP4693972B2 (ja) * 2000-09-29 2011-06-01 オリンパス株式会社 レーザ顕微鏡
JP2003322799A (ja) 2002-04-30 2003-11-14 Olympus Optical Co Ltd レーザ顕微鏡システム
JP2007504445A (ja) * 2003-08-26 2007-03-01 ブルーシフト・バイオテクノロジーズ・インコーポレーテッド 時間依存蛍光計測

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2827180A1 (en) 2013-06-24 2015-01-21 Olympus Corporation Scanning optical microscope
US9261689B2 (en) 2013-06-24 2016-02-16 Olympus Corporation Scanning optical microscope

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Publication number Publication date
US7342219B2 (en) 2008-03-11
JP2005345614A (ja) 2005-12-15
US20050263690A1 (en) 2005-12-01

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