JP4709758B2 - 呼吸器系疾患の処置用医薬組成物のための置換インドール誘導体 - Google Patents

呼吸器系疾患の処置用医薬組成物のための置換インドール誘導体 Download PDF

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Publication number
JP4709758B2
JP4709758B2 JP2006523677A JP2006523677A JP4709758B2 JP 4709758 B2 JP4709758 B2 JP 4709758B2 JP 2006523677 A JP2006523677 A JP 2006523677A JP 2006523677 A JP2006523677 A JP 2006523677A JP 4709758 B2 JP4709758 B2 JP 4709758B2
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JP
Japan
Prior art keywords
methyl
indole
acetic acid
phenoxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2006523677A
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English (en)
Japanese (ja)
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JP2007502804A5 (en:Method
JP2007502804A (ja
Inventor
ロジャー・ビクター・ボナート
アンソニー・ロナルド・クック
ティモシー・ジョン・ルーカー
ルクサナ・タスニーム・モハンメド
スティーブン・トム
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AstraZeneca AB
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AstraZeneca AB
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Publication of JP2007502804A publication Critical patent/JP2007502804A/ja
Publication of JP2007502804A5 publication Critical patent/JP2007502804A5/ja
Application granted granted Critical
Publication of JP4709758B2 publication Critical patent/JP4709758B2/ja
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Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2006523677A 2003-08-18 2004-08-16 呼吸器系疾患の処置用医薬組成物のための置換インドール誘導体 Expired - Fee Related JP4709758B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0302232-4 2003-08-18
SE0302232A SE0302232D0 (sv) 2003-08-18 2003-08-18 Novel Compounds
PCT/GB2004/003502 WO2005019171A1 (en) 2003-08-18 2004-08-16 Substituted indole derivatives for pharmaceutical composition for treating respiratory diseases

Publications (3)

Publication Number Publication Date
JP2007502804A JP2007502804A (ja) 2007-02-15
JP2007502804A5 JP2007502804A5 (en:Method) 2007-09-27
JP4709758B2 true JP4709758B2 (ja) 2011-06-22

Family

ID=28450248

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006523677A Expired - Fee Related JP4709758B2 (ja) 2003-08-18 2004-08-16 呼吸器系疾患の処置用医薬組成物のための置換インドール誘導体

Country Status (18)

Country Link
US (1) US7709521B2 (en:Method)
EP (1) EP1656347B1 (en:Method)
JP (1) JP4709758B2 (en:Method)
AR (1) AR045462A1 (en:Method)
AT (1) ATE484494T1 (en:Method)
CY (1) CY1110977T1 (en:Method)
DE (1) DE602004029580D1 (en:Method)
DK (1) DK1656347T3 (en:Method)
ES (1) ES2352201T3 (en:Method)
MY (1) MY143367A (en:Method)
PL (1) PL1656347T3 (en:Method)
PT (1) PT1656347E (en:Method)
SA (1) SA04250255B1 (en:Method)
SE (1) SE0302232D0 (en:Method)
SI (1) SI1656347T1 (en:Method)
TW (1) TW200510303A (en:Method)
UY (1) UY28473A1 (en:Method)
WO (1) WO2005019171A1 (en:Method)

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KR101864060B1 (ko) 2014-03-17 2018-06-01 이도르시아 파마슈티컬스 리미티드 아자인돌 아세트산 유도체 및 프로스타글란딘 ｄ2 수용체 조절제로서의 그의 용도
AU2015233046A1 (en) 2014-03-18 2016-11-03 Idorsia Pharmaceuticals Ltd Azaindole acetic acid derivatives and their use as prostaglandin D2 receptor modulators
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
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TWI695831B (zh) 2014-09-13 2020-06-11 香港商南北兄弟藥業投資有限公司 Ｃｒｔｈ２拮抗劑化合物及其用途
JP6770522B2 (ja) 2015-02-13 2020-10-14 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 全身性エリテマトーデスを予防し、及び／又は、治療するためのｐｔｇｄｒ−１及び／又はｐｔｇｄｒ−２アンタゴニスト
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Also Published As

Publication number Publication date
EP1656347B1 (en) 2010-10-13
UY28473A1 (es) 2005-03-31
EP1656347A1 (en) 2006-05-17
SE0302232D0 (sv) 2003-08-18
DK1656347T3 (da) 2011-01-10
US7709521B2 (en) 2010-05-04
PL1656347T3 (pl) 2011-02-28
ES2352201T3 (es) 2011-02-16
JP2007502804A (ja) 2007-02-15
WO2005019171A1 (en) 2005-03-03
PT1656347E (pt) 2010-12-09
CY1110977T1 (el) 2015-06-11
US20060264444A1 (en) 2006-11-23
SI1656347T1 (sl) 2011-01-31
DE602004029580D1 (de) 2010-11-25
TW200510303A (en) 2005-03-16
ATE484494T1 (de) 2010-10-15
MY143367A (en) 2011-04-29
SA04250255B1 (ar) 2009-02-25
AR045462A1 (es) 2005-10-26

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