MX2011012267A - Metodos para proveer pruebas de medicina personalizadas ex vivo en cuanto a neoplasmas hematologicos. - Google Patents

Metodos para proveer pruebas de medicina personalizadas ex vivo en cuanto a neoplasmas hematologicos.

Info

Publication number
MX2011012267A
MX2011012267A MX2011012267A MX2011012267A MX2011012267A MX 2011012267 A MX2011012267 A MX 2011012267A MX 2011012267 A MX2011012267 A MX 2011012267A MX 2011012267 A MX2011012267 A MX 2011012267A MX 2011012267 A MX2011012267 A MX 2011012267A
Authority
MX
Mexico
Prior art keywords
vivo
methods
personalized medicine
providing personalized
hematological neoplasms
Prior art date
Application number
MX2011012267A
Other languages
English (en)
Inventor
Juan Ballesteros
Teresa Bennett
Daniel Primo
Alberto Orfao
Jackson Coyt
Santiago Lago
Maria Matoses
Lilia Suarez
Sandra Sapia
Andrew Bosanquet
Julian Gorrochategui
Consuelo Tudela
Pilar Hernandez
Luis Ignacio Caveda
Original Assignee
Vivia Biotech Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42342776&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011012267(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vivia Biotech Sl filed Critical Vivia Biotech Sl
Publication of MX2011012267A publication Critical patent/MX2011012267A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57426—Specifically defined cancers leukemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

Se describen métodos, dispositivos y composiciones para proveer pruebas de medicina personalizadas en cuanto a neoplasmas hematológicos. En algunas modalidades, los métodos comprenden medir la eficacia de inducir apoptosis selectivamente en células malignas usando cualquier número de tratamientos de fármacos combinados alternativos potenciales. En algunas modalidades, las pruebas ex vivo son medidas usando muestras hematológicas de paciente extraídas recientemente. En otras modalidades, la eficacia es medida ex vivo usando una plataforma de citometría de flujo automatizada. Por ejemplo, al usar una plataforma de citometría de flujo automatizada, la evaluación de cientos o aún miles de fármacos y composiciones puede ser efectuada ex vivo. Así, se pueden explorar tratamientos de poli-terapia alternativos. Los fármacos no citotóxicos inducen apoptosis selectivamente en células malignas ex vivo. En algunas modalidades, los métodos descritos en la presente comprenden evaluar fármacos no citotóxicos.
MX2011012267A 2009-05-19 2010-05-19 Metodos para proveer pruebas de medicina personalizadas ex vivo en cuanto a neoplasmas hematologicos. MX2011012267A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17968509P 2009-05-19 2009-05-19
PCT/US2010/035474 WO2010135468A1 (en) 2009-05-19 2010-05-19 Methods for providing personalized medicine tests ex vivo for hematological neoplasms

Publications (1)

Publication Number Publication Date
MX2011012267A true MX2011012267A (es) 2012-04-11

Family

ID=42342776

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011012267A MX2011012267A (es) 2009-05-19 2010-05-19 Metodos para proveer pruebas de medicina personalizadas ex vivo en cuanto a neoplasmas hematologicos.

Country Status (17)

Country Link
US (2) US20100298255A1 (es)
EP (1) EP2433124B1 (es)
JP (1) JP5851984B2 (es)
CN (1) CN102460165B (es)
AR (1) AR076590A1 (es)
AU (1) AU2010249593B2 (es)
BR (1) BRPI1012980A2 (es)
CA (1) CA2762783C (es)
CL (1) CL2011002905A1 (es)
DK (1) DK2433124T3 (es)
ES (1) ES2628219T3 (es)
IL (1) IL216419A (es)
MX (1) MX2011012267A (es)
RU (1) RU2636614C2 (es)
SG (2) SG10201402346UA (es)
TW (1) TWI546537B (es)
WO (1) WO2010135468A1 (es)

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AR076590A1 (es) 2011-06-22
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