SG10201402346UA - Methods for providing personalized medicine tests ex vivo for hematological neoplasms - Google Patents

Methods for providing personalized medicine tests ex vivo for hematological neoplasms

Info

Publication number
SG10201402346UA
SG10201402346UA SG10201402346UA SG10201402346UA SG10201402346UA SG 10201402346U A SG10201402346U A SG 10201402346UA SG 10201402346U A SG10201402346U A SG 10201402346UA SG 10201402346U A SG10201402346U A SG 10201402346UA SG 10201402346U A SG10201402346U A SG 10201402346UA
Authority
SG
Singapore
Prior art keywords
vivo
methods
personalized medicine
providing personalized
hematological neoplasms
Prior art date
Application number
SG10201402346UA
Inventor
Juan Ballesteros
Teresa Bennett
Daniel Primo
Alberto Orfao
Coyt Jackson
Santiago Lago
Maria Matoses
Lilia Suarez
Sandra Sapia
Andrew Bosanquet
Julian Gorrochategui
Consuelo Tudela
Pilar Hernandez
Luis Ignacio Caveda
Original Assignee
Vivia Biotech Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42342776&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201402346U(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vivia Biotech Sl filed Critical Vivia Biotech Sl
Publication of SG10201402346UA publication Critical patent/SG10201402346UA/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57426Specifically defined cancers leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10201402346UA 2009-05-19 2010-05-19 Methods for providing personalized medicine tests ex vivo for hematological neoplasms SG10201402346UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17968509P 2009-05-19 2009-05-19

Publications (1)

Publication Number Publication Date
SG10201402346UA true SG10201402346UA (en) 2014-10-30

Family

ID=42342776

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2011085479A SG176571A1 (en) 2009-05-19 2010-05-19 Methods for providing personalized medicine tests ex vivo for hematological neoplasms
SG10201402346UA SG10201402346UA (en) 2009-05-19 2010-05-19 Methods for providing personalized medicine tests ex vivo for hematological neoplasms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2011085479A SG176571A1 (en) 2009-05-19 2010-05-19 Methods for providing personalized medicine tests ex vivo for hematological neoplasms

Country Status (17)

Country Link
US (2) US20100298255A1 (en)
EP (1) EP2433124B1 (en)
JP (1) JP5851984B2 (en)
CN (1) CN102460165B (en)
AR (1) AR076590A1 (en)
AU (1) AU2010249593B2 (en)
BR (1) BRPI1012980A2 (en)
CA (1) CA2762783C (en)
CL (1) CL2011002905A1 (en)
DK (1) DK2433124T3 (en)
ES (1) ES2628219T3 (en)
IL (1) IL216419A (en)
MX (1) MX2011012267A (en)
RU (1) RU2636614C2 (en)
SG (2) SG176571A1 (en)
TW (1) TWI546537B (en)
WO (1) WO2010135468A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130226469A1 (en) * 2008-04-01 2013-08-29 Purdue Research Foundation Gate-free flow cytometry data analysis
US8491927B2 (en) * 2009-12-02 2013-07-23 Nimble Epitech, Llc Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
US10571475B2 (en) 2010-12-03 2020-02-25 Cellply S.R.L. Rapid screening of monoclonal antibodies
TWI503545B (en) * 2010-12-24 2015-10-11 Methods of Screening Probiotics for Individual Differences
CA2833212C (en) * 2011-05-12 2020-06-09 Genentech, Inc. Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides
HUE043001T2 (en) * 2011-11-09 2019-07-29 Bristol Myers Squibb Co Treatment of hematologic malignancies with an anti-cxcr4 antibody
KR101327533B1 (en) * 2012-12-11 2013-11-08 사회복지법인 삼성생명공익재단 Novel screening system for personalized anti-cancer agents
SG11201600604QA (en) * 2013-07-29 2016-02-26 Univ California Real-time feedback system control technology platform with dynamically changing stimulations
EP2959904A1 (en) * 2014-06-27 2015-12-30 Institut De Recerca Contra La Leucemia Josep Carreras Methods for treating, diagnosing and prognosing a haematological malignancy
CN104606207A (en) * 2015-02-09 2015-05-13 南京格耀生物科技有限公司 Application of sulfamethoxazole in preparing medicament for inhibiting tumor cell metastasis and diffusion
CN104958312A (en) * 2015-05-14 2015-10-07 四川大学华西医院 Combined medicine for treating acute lymphocytic leukemia
WO2017077046A1 (en) * 2015-11-04 2017-05-11 Vivia Biotech, S.L An ex vivo method for testing cellular responsiveness of primary cell populations to a drug or combination of drugs
KR20180108572A (en) 2015-11-11 2018-10-04 셀라토 파마슈티칼즈, 인코포레이티드 Assay and method for selecting therapeutic regimens for subjects with leukemia
CN109789195A (en) 2016-04-13 2019-05-21 维维雅生物技术公司 The T cell of in vitro BITE activation
CN106093394B (en) * 2016-06-07 2017-12-26 中国人民解放军第二军医大学 Flt3 albumen is preparing liver cancer to the application in Sorafenib curative effect evaluation kit
CA3027317A1 (en) 2016-06-14 2017-12-21 Cellply S.R.L. Screening kit and method
WO2019077062A1 (en) 2017-10-18 2019-04-25 Vivia Biotech, S.L. Bite-activated car-t cells
CA3079134A1 (en) 2017-10-31 2019-05-09 Cemm-Forschungszentrum Fur Molekulare Modezin Gmbh Methods for determining selectivity of test compounds
US11116692B2 (en) 2018-06-07 2021-09-14 Gecko Alliance Group Inc. Method, system, computer program product and device for facilitating centralized control and monitoring over a network of a set of remote bathing unit systems
WO2020043716A1 (en) * 2018-08-27 2020-03-05 Katholieke Universiteit Leuven Pharmacological targeting of de novo serine/glycine synthesis
WO2020074723A1 (en) * 2018-10-11 2020-04-16 Vivia Biotech Sl A method for determining the efficacy of treatment with a combination of drugs in a subject diagnosed with a disease and a method for classifying the utility of drug combinations in treatment of said subject
US20220011296A1 (en) * 2018-11-14 2022-01-13 Dana-Farber Cancer Institute, Inc. Determining treatment response in single cells
EP3887395A4 (en) * 2018-11-30 2022-07-27 Intima Bioscience, Inc. Methods of identifying immunomodulatory genes
CN112569342A (en) * 2020-12-21 2021-03-30 中南大学 Application of caspofungin and/or pharmaceutical salt thereof in preparation of antitumor drugs and antitumor drugs
CN115531391B (en) * 2022-11-03 2023-07-18 浙江大学 Medicine for treating leukemia and application

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006162A1 (en) * 1988-01-04 1989-07-13 Oncotech Incorporated Methods and apparatus assessing tumor resistance
US5366885A (en) * 1992-06-09 1994-11-22 Barranco Iii Sam C Method and kit for testing tumors for drug sensitivity
US5474909A (en) * 1992-08-07 1995-12-12 Anticancer, Inc. Noncolorimetric histoculture method for predicting drug response of tumors
WO1996022085A1 (en) * 1995-01-17 1996-07-25 Pfizer Inc. The use of sertraline to treat cancer patients
US6825174B2 (en) * 1995-06-07 2004-11-30 East Carolina University Composition, formulations & method for prevention & treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) & inflammation
US5736129A (en) * 1995-11-17 1998-04-07 Medenica; Rajko D. Flow cytometric pharmacosensitivity assay and method of cancer treatment
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
WO1997045105A1 (en) * 1996-05-24 1997-12-04 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating or preventing diseases of body passageways
US8828432B2 (en) * 1996-10-28 2014-09-09 General Mills, Inc. Embedding and encapsulation of sensitive components into a matrix to obtain discrete controlled release particles
US7026447B2 (en) * 1997-10-09 2006-04-11 Human Genome Sciences, Inc. 53 human secreted proteins
US20030049618A1 (en) * 1997-03-07 2003-03-13 Ruben Steven M. 186 human secreted proteins
US20030059471A1 (en) * 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
US6207717B1 (en) * 1999-01-12 2001-03-27 Dow Corning Corporation Entrapment of vitamins with an elastomeric silicone polyether
US6890904B1 (en) * 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
US6911306B1 (en) * 1999-10-18 2005-06-28 Emory University TMS1 compositions and methods of use
WO2001032677A1 (en) * 1999-11-04 2001-05-10 Human Genome Sciences, Inc. Uteroglobin-like polynucleotides, polypeptides, and antibodies
US6448030B1 (en) * 2000-02-18 2002-09-10 University Of Nevada-Las Vegas Method for predicting the efficacy of anti-cancer drugs
US7723303B2 (en) * 2000-08-24 2010-05-25 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
AU2002220265A1 (en) * 2000-11-03 2002-05-15 University Of Vermont And State Agricultural College Compositions for inhibiting grb7
WO2002046750A2 (en) * 2000-11-13 2002-06-13 Vanderbilt University Methods of predicting chemotherapy response
US20050013853A1 (en) * 2000-11-29 2005-01-20 Irit Gil-Ad Anti-proliferative drugs
IL139975A0 (en) * 2000-11-29 2002-02-10 Univ Ramot Anti proliferative drugs
DE10064997A1 (en) * 2000-12-23 2002-06-27 Merck Patent Gmbh New 1-benzoyl-3-phenyl-tetrahydropyridazine derivatives, useful for treating e.g. allergy, are selective inhibitors of phosphodiesterase IV, and new intermediates
IL156460A0 (en) * 2001-01-31 2004-01-04 Pfizer Prod Inc Ether derivatives useful as inhibitors of pde4 isozymes
WO2002062792A1 (en) * 2001-02-02 2002-08-15 Takeda Chemical Industries, Ltd. Jnk inhibitor
ATE412893T1 (en) * 2001-02-14 2008-11-15 Evotec Ag DISPENSION DEVICE
JP4634694B2 (en) * 2001-03-23 2011-02-16 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド Fatty alcohol drug complex
US20070021360A1 (en) * 2001-04-24 2007-01-25 Nyce Jonathan W Compositions, formulations and kit with anti-sense oligonucleotide and anti-inflammatory steroid and/or obiquinone for treatment of respiratory and lung disesase
US20040072824A1 (en) * 2001-06-01 2004-04-15 Adam Telerman Methods and compositions for the treatment of cancer
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
CA2466138A1 (en) * 2001-11-02 2003-05-15 Shen Wu Wang B-cell lymphoma specific antigen for use in diagnosis and treatment of b-cell malignancies
US20040072181A1 (en) * 2002-01-22 2004-04-15 Whitehead Alexander Steven Methods for determining drug responsiveness
GB0202337D0 (en) * 2002-02-01 2002-03-20 Univ Birmingham Cancer treatment
GB0203276D0 (en) * 2002-02-12 2002-03-27 Novartis Ag Organic compounds
DE10214388A1 (en) * 2002-03-30 2003-10-16 Cognis Deutschland Gmbh Process for the production of solid materials
WO2003102158A2 (en) * 2002-05-31 2003-12-11 The Forsyth Institute Methods for increasing bone density
AU2003265264A1 (en) * 2002-07-09 2004-01-23 Point Therapeutics, Inc. Methods and compositions relating to isoleucine boroproline compounds
CN1389462A (en) * 2002-07-12 2003-01-08 复旦大学 Grandifoliate burchellin and its homologue and application in preparing composite medicine
US20060009378A1 (en) * 2002-11-14 2006-01-12 Itshak Golan Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
US20040101477A1 (en) * 2002-11-27 2004-05-27 Xanthus Life Sciences, Inc. Individualization of therapy with anesthetics
WO2004091572A2 (en) * 2003-04-09 2004-10-28 Biodelivery Sciences International, Inc. Cochleate compositions directed against expression of proteins
EP1624858B1 (en) * 2003-04-09 2018-06-06 Rutgers, the State University of New Jersey Novel encochleation methods
US7329638B2 (en) * 2003-04-30 2008-02-12 The Regents Of The University Of Michigan Drug delivery compositions
US20050136043A1 (en) * 2003-08-07 2005-06-23 Ludwig Institute For Cancer Research TGFbeta signaling inhibitors
SE0302232D0 (en) * 2003-08-18 2003-08-18 Astrazeneca Ab Novel Compounds
WO2005020933A2 (en) * 2003-09-02 2005-03-10 University Of South Florida Nanoparticles for drug-delivery
WO2005081687A2 (en) * 2003-09-30 2005-09-09 Centocor, Inc. Human hinge core mimetibodies, compositions, methods and uses
US20050143378A1 (en) * 2003-12-29 2005-06-30 Yun Anthony J. Treatment of conditions through pharmacological modulation of the autonomic nervous system
US9173847B2 (en) * 2003-10-10 2015-11-03 Veloxis Pharmaceuticals A/S Tablet comprising a fibrate
EP1691891A2 (en) * 2003-11-13 2006-08-23 The Board Of Regents, The University Of Texas System Inhibition of trp channels as a treatment for cardiac hypertrophy and heart failure
US7211275B2 (en) * 2004-01-16 2007-05-01 Massachusetts Institute Of Technology Composite materials for controlled release of water soluble products
US20070166363A1 (en) * 2004-02-19 2007-07-19 Lane Roger M Use of cholinesterase inhibitors for treating vascular depression
EP1746976B1 (en) * 2004-05-03 2017-01-11 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery
US8529889B2 (en) * 2004-06-29 2013-09-10 Massachusetts Institute Of Technology Methods and compositions related to the modulation of intercellular junctions
US20060009506A1 (en) * 2004-07-09 2006-01-12 Odyssey Thera, Inc. Drugs for the treatment of neoplastic disorders
ES2341559T3 (en) * 2004-07-23 2010-06-22 The Medicines Company (Leipzig) Gmbh PIRIDO (3 ', 2': 4,5) HAVING (3,2-D) PYRIMIDINES AND PIRIDO (3 ', 2': 4,5) FURO (3,2-D) PIRIMIDINES REPLACED FOR USE AS INHIBITORS OF THE RELEASE OF PDA-4 AND / OR TNF-ALFA.
US7566548B2 (en) * 2004-08-13 2009-07-28 University Of Massachusetts Methods for identifying therapeutic agents and for treating disease
US20060039975A1 (en) * 2004-08-20 2006-02-23 Zalman Vilkov Paroxetine formulations
EP1627610A1 (en) * 2004-08-21 2006-02-22 TLT Medical Ltd Drug delivery throug application in nails
US7393662B2 (en) * 2004-09-03 2008-07-01 Centocor, Inc. Human EPO mimetic hinge core mimetibodies, compositions, methods and uses
EP1792519A4 (en) * 2004-09-10 2010-09-15 Otologics Llc Adjustable bone bracket
US20060058966A1 (en) * 2004-09-15 2006-03-16 Bruckner Howard W Methods and systems for guiding selection of chemotherapeutic agents
US20060062734A1 (en) * 2004-09-20 2006-03-23 Melker Richard J Methods and systems for preventing diversion of prescription drugs
JP2008514612A (en) * 2004-09-23 2008-05-08 ミシャロウ、アレクサンダー Methods of modulating neurotransmitter systems by inducing counter adaptation
EP2444071A1 (en) * 2004-09-27 2012-04-25 Sigmoid Pharma Limited Minicapsule formulations
US20090011410A1 (en) * 2004-10-20 2009-01-08 Masato Mitsuhashi Method for tailoring administration of drugs by quantitation of mrna
DE602005011844D1 (en) * 2004-11-02 2009-01-29 Pfizer SULFONYLBENZIMIDAZOLDERIVATE
US20090082304A1 (en) * 2004-11-12 2009-03-26 Northwestern University Methods of Treating Hematological Malignancies with Nucleoside Analog Drugs
US20080096872A1 (en) * 2004-12-22 2008-04-24 Friedman Robert S Composition for Treatment of Pain Specification
CA2594505A1 (en) * 2005-02-01 2006-08-10 Icagen, Inc. Imines as ion channel modulators
CN1834659A (en) * 2005-03-17 2006-09-20 希森美康株式会社 Sample analyzer and sample analyzing method
WO2007053189A2 (en) * 2005-06-01 2007-05-10 Northwestern University Compositions and methods for altering immune function
US7655421B2 (en) * 2005-06-17 2010-02-02 Ciencia, Inc. Cytometer on a chip
HUE042561T2 (en) * 2005-06-30 2019-07-29 Janssen Biotech Inc Anti-IL-23 antibodies, compositions, methods and uses
US20090118288A1 (en) * 2005-07-21 2009-05-07 Astrazeneca Ab N-Benzyl-Morpholine Derivatives as Modulators of the Chemokine Receptor
WO2007015926A2 (en) * 2005-07-25 2007-02-08 Oregon Health And Science University Multiparameter flow cytometric cytometric cytotoxicity systems, methods, compositions and kits for evaluating the susceptibility of cancer
AR058071A1 (en) * 2005-10-03 2008-01-23 Astrazeneca Ab DERIVATIVES OF DIHYDROPIRAZOLO (3,4-E) (1,4) DIAZEPINA. PROCESSES OF OBTAINING AND PHARMACEUTICAL COMPOSITIONS.
EP1931798A1 (en) * 2005-10-05 2008-06-18 AstraZeneca UK Limited Method to predict or monitor the response of a patient to an erbb receptor drug
US20080318252A1 (en) * 2007-04-23 2008-12-25 Scott Kachlany Rapid assay to test anti-cancer drugs under physiological conditions
EA200801145A1 (en) * 2005-12-02 2008-10-30 Пфайзер Лимитед SPYROCYCLIC DERIVATIVES OF HINAZOLIN AS PDE7 INHIBITORS
US20070178165A1 (en) * 2005-12-15 2007-08-02 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for parenteral administration
AU2007223560A1 (en) * 2006-03-01 2007-09-13 Tristrata, Inc. Composition and method for topical treatment of tar-responsive dermatological disorders
DE602007009807D1 (en) * 2006-03-06 2010-11-25 Raqualia Pharma Inc SULFONYLBENZIMIDAZOLDERIVATE
EP1996551A2 (en) * 2006-03-07 2008-12-03 AstraZeneca AB Piperidine derivatives, their process for preparation, their use as therapeutic agents and pharmaceutical compositions containing them.
US20090029958A1 (en) * 2006-03-08 2009-01-29 Lilian Alcaraz Phenethanolamine derivatives as beta2 adrenoreceptor agonists
TW200808763A (en) * 2006-05-08 2008-02-16 Astrazeneca Ab Novel compounds I
EP2032983A2 (en) * 2006-05-24 2009-03-11 Cellumen, Inc. Method for modeling a disease
TW200815469A (en) * 2006-06-23 2008-04-01 Astrazeneca Ab Compounds
CN101511775A (en) * 2006-06-29 2009-08-19 詹森药业有限公司 Butyl and butynyl benzyl amine compounds
CA2659655A1 (en) * 2006-08-08 2008-02-21 Alan M. Fogelman Salicylanilides enhance oral delivery of therapeutic peptides
US20080066739A1 (en) * 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
ME02829B (en) * 2006-09-26 2018-01-20 Celgene Corp 5-substituted quinazolinone derivatives as anti-cancer agents
US8841300B2 (en) * 2006-10-02 2014-09-23 Jerry M. Held Treatment for Parkinson's disease—combination high dose serotonergic synaptic reuptake inhibitor with phosphodiesterase inhibitor
EP2078016B1 (en) * 2006-10-19 2012-02-01 Signal Pharmaceuticals LLC Heteroaryl compounds, compositions thereof, and methods of treatment therewith
US7661326B2 (en) * 2006-10-26 2010-02-16 Beckman Coulter, Inc. Apparatus for aspirating and dispensing liquids in an automated analyzer
TW200825084A (en) * 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
GB0625322D0 (en) * 2006-12-19 2007-01-24 Pharmakodex Ltd Pharmaceutical compositions
CN101677957A (en) * 2007-02-05 2010-03-24 卡比兰生物外科公司 The polymer formulations that is used for delivery of bioactive agents
GB0704000D0 (en) * 2007-03-01 2007-04-11 Astrazeneca Ab Salts 670
AU2008222745A1 (en) * 2007-03-07 2008-09-12 Janssen Pharmaceutica N.V. Substituted phenoxy thiazolidinediones as estrogen related receptor-alpha modulators
GB0707127D0 (en) * 2007-04-13 2007-05-23 Zysis Ltd Pharmaceutical compositions
US20090004281A1 (en) * 2007-06-26 2009-01-01 Biovail Laboratories International S.R.L. Multiparticulate osmotic delivery system
US7943658B2 (en) * 2007-07-23 2011-05-17 Bristol-Myers Squibb Company Indole indane amide compounds useful as CB2 agonists and method
SI2200588T1 (en) * 2007-09-25 2019-08-30 Solubest Ltd. Compositions comprising lipophilic active compounds and method for their preparation
US8354417B2 (en) * 2007-09-26 2013-01-15 Celgene Corporation Solid forms comprising 3-(2,5-dimethyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, compositions comprising the same, and methods of using the same
WO2009051238A1 (en) * 2007-10-18 2009-04-23 Riken Mouse having human leukemic stem cell and leukemic non-stem cell amplified therein, and method for production thereof
US20090124675A1 (en) * 2007-10-19 2009-05-14 Burnham Institute For Medical Research Inhibitors of anti-apoptotic proteins
CN101896068A (en) * 2007-10-19 2010-11-24 伯恩哈姆医学研究协会 The naphthyl inhibitor of anti-apoptotic proteins
EP2249806A2 (en) * 2008-01-08 2010-11-17 Sirtris Pharmaceuticals, Inc. Resveratrol formulations
CA2721065C (en) * 2008-05-27 2016-09-27 Astrazeneca Ab Phenoxypyridinylamide derivatives and their use as pde4 inhibitors
EP2304436A1 (en) * 2008-07-10 2011-04-06 Nodality, Inc. Methods for diagnosis, prognosis and treatment
TWI453207B (en) * 2008-09-08 2014-09-21 Signal Pharm Llc Aminotriazolopyridines, compositions thereof, and methods of treatment therewith
US20100099109A1 (en) * 2008-10-17 2010-04-22 Nodality, Inc., A Delaware Corporation Methods for Analyzing Drug Response
KR101046883B1 (en) * 2008-11-19 2011-07-06 재단법인 아산사회복지재단 How to collectively determine sensitivity to anticancer drugs

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JP2012527627A (en) 2012-11-08
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US20170205395A1 (en) 2017-07-20
MX2011012267A (en) 2012-04-11
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IL216419A (en) 2016-05-31
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AU2010249593A1 (en) 2012-01-12
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JP5851984B2 (en) 2016-02-03
WO2010135468A1 (en) 2010-11-25

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