TW200510303A - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- TW200510303A TW200510303A TW093123728A TW93123728A TW200510303A TW 200510303 A TW200510303 A TW 200510303A TW 093123728 A TW093123728 A TW 093123728A TW 93123728 A TW93123728 A TW 93123728A TW 200510303 A TW200510303 A TW 200510303A
- Authority
- TW
- Taiwan
- Prior art keywords
- novel compounds
- relates
- present
- pharmaceutical compounds
- respiratory disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0302232A SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Novel Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200510303A true TW200510303A (en) | 2005-03-16 |
Family
ID=28450248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW093123728A TW200510303A (en) | 2003-08-18 | 2004-08-06 | Novel compounds |
Country Status (18)
Country | Link |
---|---|
US (1) | US7709521B2 (zh) |
EP (1) | EP1656347B1 (zh) |
JP (1) | JP4709758B2 (zh) |
AR (1) | AR045462A1 (zh) |
AT (1) | ATE484494T1 (zh) |
CY (1) | CY1110977T1 (zh) |
DE (1) | DE602004029580D1 (zh) |
DK (1) | DK1656347T3 (zh) |
ES (1) | ES2352201T3 (zh) |
MY (1) | MY143367A (zh) |
PL (1) | PL1656347T3 (zh) |
PT (1) | PT1656347E (zh) |
SA (1) | SA04250255B1 (zh) |
SE (1) | SE0302232D0 (zh) |
SI (1) | SI1656347T1 (zh) |
TW (1) | TW200510303A (zh) |
UY (1) | UY28473A1 (zh) |
WO (1) | WO2005019171A1 (zh) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
SE0303180D0 (sv) * | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
US7714132B2 (en) | 2004-03-11 | 2010-05-11 | Actelion Pharmaceuticals, Ltd. | Tetrahydropyridoindole derivatives |
PT1833791E (pt) | 2004-12-27 | 2011-10-19 | Actelion Pharmaceuticals Ltd | Derivados de 2,3,4,9-tetra-hidro-1h-carbazol como antgonistas do receptor crth2 |
GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
GB0505048D0 (en) * | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
JP5072594B2 (ja) | 2005-07-22 | 2012-11-14 | 塩野義製薬株式会社 | Pgd2受容体アンタゴニスト活性を有するインドール誘導体 |
US7842692B2 (en) | 2005-07-22 | 2010-11-30 | Shionogi & Co., Ltd. | Azaindole derivative having PGD2 receptor antagonistic activity |
GB0521275D0 (en) * | 2005-10-19 | 2005-11-30 | Argenta Discovery Ltd | 3-Aminoindole compounds |
WO2007138282A2 (en) * | 2006-05-26 | 2007-12-06 | Astrazeneca Ab | Bi-aryl or aryl-heteroaryl substituted indoles |
WO2007149312A2 (en) * | 2006-06-16 | 2007-12-27 | The Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting or reducing hair loss, acne, rosacea, prostate cancer, and bph |
US20150072963A1 (en) * | 2006-06-16 | 2015-03-12 | The Trustees Of The University Of Pennsylvania | Compositions and methods for regulating hair growth |
PL2046740T3 (pl) | 2006-07-22 | 2012-10-31 | Oxagen Ltd | Związki o aktywności antagonisty CRTH2 |
ES2374321T3 (es) | 2006-08-07 | 2012-02-15 | Actelion Pharmaceuticals Ltd. | Derivados del ácido (3-amino-1,2,3,4-tetrahidro-9h-carbazol-9-il)-acético. |
CA2682391C (en) | 2007-04-11 | 2014-07-08 | Kissei Pharmaceutical Co., Ltd. | (aza)indole derivative and use thereof for medical purposes |
US7960567B2 (en) * | 2007-05-02 | 2011-06-14 | Amgen Inc. | Compounds and methods useful for treating asthma and allergic inflammation |
DK2327693T3 (da) | 2007-12-14 | 2012-08-13 | Pulmagen Therapeutics Asthma Ltd | Indoler og terapeutisk anvendelse deraf |
MY155133A (en) | 2008-01-18 | 2015-09-15 | Atopix Therapeutics Ltd | Compounds having crth2 antagonist activity |
US7750027B2 (en) * | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
JP2011509990A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Crth2アンタゴニスト活性を有する化合物 |
EP2240444A1 (en) | 2008-01-22 | 2010-10-20 | Oxagen Limited | Compounds having crth2 antagonist activity |
WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
RU2011130793A (ru) | 2008-12-25 | 2013-01-27 | Тайсо Фармасьютикал, Ко., Лтд. | Изохинолиновое производное |
SG176571A1 (en) * | 2009-05-19 | 2012-01-30 | Vivia Biotech Sl | Methods for providing personalized medicine tests ex vivo for hematological neoplasms |
SG177286A1 (en) * | 2009-07-06 | 2012-02-28 | Astrazeneca Ab | Intermediates and processes for the preparation of 4- (acetylamino) ) -3- [ (4-chloro-phenyl) thio] -2-methyl-1h-indole-1-acetic acid |
AU2011215638B2 (en) | 2010-02-11 | 2016-04-28 | Vanderbilt University | Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as mGluR4 allosteric potentiators, compounds, and methods of treating neurological dysfunction |
RU2562255C2 (ru) | 2010-03-22 | 2015-09-10 | Актелион Фармасьютиклз Лтд | Производные 3-(гетероариламино)-1,2,3,4-тетрагидро-9н-карбазола и их применение в качестве модуляторов рецепторов простагландина d2 |
WO2011162274A1 (ja) | 2010-06-23 | 2011-12-29 | 大正製薬株式会社 | イソキノリン誘導体 |
EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
KR101928595B1 (ko) | 2011-04-14 | 2018-12-12 | 이도르시아 파마슈티컬스 리미티드 | 7-(헤테로아릴-아미노)-6,7,8,9-테트라히드로피리도[1,2-a]인돌 아세트산 유도체 및 프로스타글란딘 d2 수용체 조절자로서의 이의 용도 |
EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
AU2012351342A1 (en) | 2011-12-16 | 2014-07-24 | Atopix Therapeutics Limited | Combination of CRTH2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
CA2867901A1 (en) | 2012-03-21 | 2013-09-26 | The Trustees Of The University Of Pennsylvania | Compositions and methods for regulating hair growth |
HUE039614T2 (hu) | 2014-03-17 | 2019-01-28 | Idorsia Pharmaceuticals Ltd | Azaindol-ecetsav-származékok és prosztaglandin D2 receptor modulátorokként történõ alkalmazásuk |
CA2938107A1 (en) | 2014-03-18 | 2015-09-24 | Actelion Pharmaceuticals Ltd | Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators |
GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
TWI695831B (zh) | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Crth2拮抗劑化合物及其用途 |
CA2993972A1 (en) | 2015-07-30 | 2017-02-02 | The Trustees Of The University Of Pennsylvania | Single nucleotide polymorphic alleles of human dp-2 gene for detection of susceptibility to hair growth inhibition by pgd2 |
UA123156C2 (uk) | 2015-09-15 | 2021-02-24 | Ідорсія Фармасьютікалз Лтд | КРИСТАЛІЧНА ФОРМА (S)-2-(8-((5-ХЛОРПІРИМІДИН-2-ІЛ)(МЕТИЛ)АМІНО)-2-ФТОР-6,7,8,9-ТЕТРАГІДРО-5H-ПІРИДО[3,2-b]ІНДОЛ-5-ІЛ)ОЦТОВОЇ КИСЛОТИ, ЇЇ ЗАСТОСУВАННЯ ТА ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЇЇ МІСТИТЬ |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE790679A (fr) * | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
JPH0615542B2 (ja) | 1986-07-22 | 1994-03-02 | 吉富製薬株式会社 | ピラゾロピリジン化合物 |
US5095031A (en) * | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
WO1993005020A1 (en) | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
FR2692574B1 (fr) | 1992-06-23 | 1995-06-23 | Sanofi Elf | Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles. |
PL175788B1 (pl) | 1993-02-24 | 1999-02-26 | Merck & Co Inc | Amidowe pochodne indolu i zawierające je kompozycje farmaceutyczne |
US5486525A (en) | 1993-12-16 | 1996-01-23 | Abbott Laboratories | Platelet activating factor antagonists: imidazopyridine indoles |
US5567711A (en) | 1995-04-19 | 1996-10-22 | Abbott Laboratories | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists |
TW472045B (en) | 1996-09-25 | 2002-01-11 | Astra Ab | Protein kinase C inhibitor compounds, method for their preparation, pharmaceutical composition thereof and intermediate used for their preparation |
WO1999009007A1 (en) | 1997-08-21 | 1999-02-25 | American Home Products Corporation | Solid phase synthesis of 2,3-disubstituted indole compounds |
AU2003099A (en) | 1997-12-19 | 1999-07-12 | Eli Lilly And Company | Method for treating diabetes |
US6916841B2 (en) | 1998-02-25 | 2005-07-12 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
WO2000078761A1 (en) | 1999-06-23 | 2000-12-28 | Sepracor, Inc. | Indolyl-benzimidazole antibacterials, and methods of use thereof |
WO2001032621A1 (fr) | 1999-10-29 | 2001-05-10 | Wakunaga Pharmaceutical Co., Ltd. | Nouveaux derives d'indole, et medicaments contenant lesdits derives comme principe actif |
EE05180B1 (et) | 1999-12-24 | 2009-06-15 | Aventis Pharma Limited | Asaindooli sisaldav farmatseutiline kompositsioon raviotstarbeliseks kasutamiseks, asaindoolid ning nende kasutamine ravimite valmistamiseks, mis on ette nhtud proteiinikinaasi kataltilise toime prssimiseks |
EP1289952A1 (en) | 2000-05-31 | 2003-03-12 | AstraZeneca AB | Indole derivatives with vascular damaging activity |
US6878522B2 (en) * | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
TWI317634B (en) | 2001-12-13 | 2009-12-01 | Nat Health Research Institutes | Aroyl indoles compounds |
WO2003064387A2 (en) | 2002-02-01 | 2003-08-07 | F. Hoffman-La Roche Ag | Substituted indoles as alpha-1 agonists |
SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
EP2423190A1 (en) | 2002-05-16 | 2012-02-29 | Shionogi&Co., Ltd. | Compounds Exhibiting PGD 2 Receptor Antagonism |
SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0202463D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
AU2004283139A1 (en) | 2003-10-14 | 2005-05-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
GB2422831A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
WO2007138282A2 (en) | 2006-05-26 | 2007-12-06 | Astrazeneca Ab | Bi-aryl or aryl-heteroaryl substituted indoles |
US20090318526A1 (en) | 2006-06-08 | 2009-12-24 | Uno Jacob Weber | Use of cannabinoid receptor agonists as hypothermia inducing drugs for the treatment of ischemia |
JP5237938B2 (ja) | 2006-06-28 | 2013-07-17 | サノフイ | 新規なcxcr2阻害剤 |
-
2003
- 2003-08-18 SE SE0302232A patent/SE0302232D0/xx unknown
-
2004
- 2004-08-06 TW TW093123728A patent/TW200510303A/zh unknown
- 2004-08-16 SA SA04250255A patent/SA04250255B1/ar unknown
- 2004-08-16 WO PCT/GB2004/003502 patent/WO2005019171A1/en active Search and Examination
- 2004-08-16 SI SI200431554T patent/SI1656347T1/sl unknown
- 2004-08-16 DE DE602004029580T patent/DE602004029580D1/de active Active
- 2004-08-16 MY MYPI20043328A patent/MY143367A/en unknown
- 2004-08-16 US US10/568,889 patent/US7709521B2/en not_active Expired - Fee Related
- 2004-08-16 PL PL04768065T patent/PL1656347T3/pl unknown
- 2004-08-16 EP EP04768065A patent/EP1656347B1/en not_active Not-in-force
- 2004-08-16 PT PT04768065T patent/PT1656347E/pt unknown
- 2004-08-16 DK DK04768065.7T patent/DK1656347T3/da active
- 2004-08-16 JP JP2006523677A patent/JP4709758B2/ja not_active Expired - Fee Related
- 2004-08-16 AT AT04768065T patent/ATE484494T1/de active
- 2004-08-16 ES ES04768065T patent/ES2352201T3/es active Active
- 2004-08-17 UY UY28473A patent/UY28473A1/es unknown
- 2004-08-18 AR ARP040102959A patent/AR045462A1/es not_active Application Discontinuation
-
2010
- 2010-12-09 CY CY20101101133T patent/CY1110977T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP4709758B2 (ja) | 2011-06-22 |
PT1656347E (pt) | 2010-12-09 |
SI1656347T1 (sl) | 2011-01-31 |
JP2007502804A (ja) | 2007-02-15 |
SA04250255B1 (ar) | 2009-02-25 |
EP1656347A1 (en) | 2006-05-17 |
US20060264444A1 (en) | 2006-11-23 |
ATE484494T1 (de) | 2010-10-15 |
EP1656347B1 (en) | 2010-10-13 |
US7709521B2 (en) | 2010-05-04 |
ES2352201T3 (es) | 2011-02-16 |
CY1110977T1 (el) | 2015-06-11 |
DE602004029580D1 (de) | 2010-11-25 |
UY28473A1 (es) | 2005-03-31 |
AR045462A1 (es) | 2005-10-26 |
PL1656347T3 (pl) | 2011-02-28 |
WO2005019171A1 (en) | 2005-03-03 |
MY143367A (en) | 2011-04-29 |
SE0302232D0 (sv) | 2003-08-18 |
DK1656347T3 (da) | 2011-01-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200510301A (en) | Novel compounds | |
TW200510303A (en) | Novel compounds | |
TW200407305A (en) | Novel compounds | |
SE0202241D0 (sv) | Novel Compounds | |
SE0303180D0 (sv) | Novel compounds | |
TW200612892A (en) | Novel compounds | |
TW200732296A (en) | Novel compounds | |
TW200505837A (en) | Novel compounds | |
TW200519075A (en) | Novel compounds | |
MX2007011847A (es) | Derivados de pirimidindiona como antagonistas del receptor de procineticina 2. | |
TW200630336A (en) | Novel compounds | |
TW200621690A (en) | Novel compounds | |
TW200745003A (en) | Novel compounds | |
GB0510143D0 (en) | Novel compounds A1 | |
SE0301009D0 (sv) | Novel compounds | |
MX2007003108A (es) | Compuestos imidazo-3-il-amina sustituidos y biciclicos. | |
WO2007052023A3 (en) | Novel compounds | |
MY153719A (en) | Prokineticin 1 receptor antagonists | |
PL1891004T3 (pl) | Pentafluorosulfanylo-podstawiony związek i jego zastosowanie do wytwarzania środków leczniczych | |
MX2007002393A (es) | Compuestos indolicos sustituidos y su uso como moduladores del receptor de 5-hidroxitriptamina 6 (5-ht6). | |
WO2007079214A3 (en) | Prokineticin 2 receptor antagonists | |
WO2007138282A3 (en) | Bi-aryl or aryl-heteroaryl substituted indoles | |
TW200508201A (en) | Novel process for the preparation of roflumilast | |
MX2008013196A (es) | 5-amido-2-carboxiamida-indoles. | |
TW200745039A (en) | Isotopically substituted pantoprazole |