SE0302232D0 - Novel Compounds - Google Patents
Novel CompoundsInfo
- Publication number
- SE0302232D0 SE0302232D0 SE0302232A SE0302232A SE0302232D0 SE 0302232 D0 SE0302232 D0 SE 0302232D0 SE 0302232 A SE0302232 A SE 0302232A SE 0302232 A SE0302232 A SE 0302232A SE 0302232 D0 SE0302232 D0 SE 0302232D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel compounds
- useful
- formula
- relates
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0302232A SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Novel Compounds |
TW093123728A TW200510303A (en) | 2003-08-18 | 2004-08-06 | Novel compounds |
ES04768065T ES2352201T3 (es) | 2003-08-18 | 2004-08-16 | Derivados de indol sustituidos para composiciones farmacéuticas para tratar enfermedades respiratorias. |
JP2006523677A JP4709758B2 (ja) | 2003-08-18 | 2004-08-16 | 呼吸器系疾患の処置用医薬組成物のための置換インドール誘導体 |
US10/568,889 US7709521B2 (en) | 2003-08-18 | 2004-08-16 | Substituted indole derivatives for pharmaceutical compositions for treating respiratory diseases |
SA04250255A SA04250255B1 (ar) | 2003-08-18 | 2004-08-16 | مشتقات اندول مستبدلة لعمل تركيبات صيدلانية لعلاج امراض يسببها بروستجلاندين d2 |
AT04768065T ATE484494T1 (de) | 2003-08-18 | 2004-08-16 | Substituierte indolderivate für eine pharmazeutische zusammensetzung zur behandlung von atemwegserkrankungen |
MYPI20043328A MY143367A (en) | 2003-08-18 | 2004-08-16 | Substituted indole derivatives for pharmaceutical compositions for treating respiratory diseases |
PL04768065T PL1656347T3 (pl) | 2003-08-18 | 2004-08-16 | Podstawione pochodne indolu do środków farmaceutycznych do leczenia chorób układu oddechowego |
DK04768065.7T DK1656347T3 (da) | 2003-08-18 | 2004-08-16 | Substituerede indolderivater til farmaceutisk sammensætning til behandling af luftvejssygdomme |
DE602004029580T DE602004029580D1 (de) | 2003-08-18 | 2004-08-16 | Substituierte indolderivate für eine pharmazeutische zusammensetzung zur behandlung von atemwegserkrankungen |
SI200431554T SI1656347T1 (sl) | 2003-08-18 | 2004-08-16 | Substituirani indolni derivati za farmacevtske sestavke za zdravljenje respiratornih bolezni |
EP04768065A EP1656347B1 (en) | 2003-08-18 | 2004-08-16 | Substituted indole derivatives for pharmaceutical composition for treating respiratory diseases |
PCT/GB2004/003502 WO2005019171A1 (en) | 2003-08-18 | 2004-08-16 | Substituted indole derivatives for pharmaceutical composition for treating respiratory diseases |
PT04768065T PT1656347E (pt) | 2003-08-18 | 2004-08-16 | Derivados de indole substituídos para composição farmacêutica para tratar doenças respiratórias |
UY28473A UY28473A1 (es) | 2003-08-18 | 2004-08-17 | Nuevos compuestos |
ARP040102959A AR045462A1 (es) | 2003-08-18 | 2004-08-18 | DERIVADOS DE INDOLES SUSTITUIDOS eTILES COMO COMPUESTOS FARMACEUTICOS PARA EL TRATAMIENTO DE ENFERMEDADES RESPIRATORIAS |
CY20101101133T CY1110977T1 (el) | 2003-08-18 | 2010-12-09 | Υποκατεστημενα παραγωγα ινδολης για φαρμακευτικη συνθεση για θεραπεια ασθενειων του αναπνευστικου |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0302232A SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Novel Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0302232D0 true SE0302232D0 (sv) | 2003-08-18 |
Family
ID=28450248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0302232A SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Novel Compounds |
Country Status (18)
Country | Link |
---|---|
US (1) | US7709521B2 (xx) |
EP (1) | EP1656347B1 (xx) |
JP (1) | JP4709758B2 (xx) |
AR (1) | AR045462A1 (xx) |
AT (1) | ATE484494T1 (xx) |
CY (1) | CY1110977T1 (xx) |
DE (1) | DE602004029580D1 (xx) |
DK (1) | DK1656347T3 (xx) |
ES (1) | ES2352201T3 (xx) |
MY (1) | MY143367A (xx) |
PL (1) | PL1656347T3 (xx) |
PT (1) | PT1656347E (xx) |
SA (1) | SA04250255B1 (xx) |
SE (1) | SE0302232D0 (xx) |
SI (1) | SI1656347T1 (xx) |
TW (1) | TW200510303A (xx) |
UY (1) | UY28473A1 (xx) |
WO (1) | WO2005019171A1 (xx) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
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TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) * | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0301569D0 (sv) * | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
SE0303180D0 (sv) * | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
PT1725553E (pt) | 2004-03-11 | 2008-07-16 | Actelion Pharmaceuticals Ltd | Derivados de tetra-hidropiridoindole |
NZ556657A (en) | 2004-12-27 | 2010-10-29 | Actelion Pharmaceuticals Ltd | 2,3,4,9-tetrahydro-1H-carbazole derivatives as CRTH2 receptor antagonists |
GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
GB0505048D0 (en) * | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
EP1911759A4 (en) | 2005-07-22 | 2010-07-21 | Shionogi & Co | AZAINDOL DERIVATIVE ANTAGONISTIC EFFECT ON PGD2 RECEPTOR |
EP2397476A3 (en) | 2005-07-22 | 2011-12-28 | Shionogi & Co., Ltd. | Indole derivative having PGD2 receptor antagonist activity |
GB0521275D0 (en) * | 2005-10-19 | 2005-11-30 | Argenta Discovery Ltd | 3-Aminoindole compounds |
CN102558021A (zh) * | 2006-05-26 | 2012-07-11 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
US20150072963A1 (en) * | 2006-06-16 | 2015-03-12 | The Trustees Of The University Of Pennsylvania | Compositions and methods for regulating hair growth |
SI2037967T1 (sl) | 2006-06-16 | 2017-04-26 | The Trustees Of The University Of Pennsylvania | Antagonisti receptorja za prostaglandin d2 za zdravljenje androgene alopecije |
PT2046740E (pt) | 2006-07-22 | 2012-08-28 | Oxagen Ltd | Compostos com atividade antagonista do crth2 |
PL2051962T3 (pl) | 2006-08-07 | 2012-03-30 | Actelion Pharmaceuticals Ltd | Pochodne kwasu (3-amino-1,2,3,4-tetrahydro-9h-karbazol-9-ilo)-octowego |
PL2133332T3 (pl) | 2007-04-11 | 2014-02-28 | Kissei Pharmaceutical | Pochodna aza(indolu) i jej zastosowanie do celów medycznych |
US7960567B2 (en) * | 2007-05-02 | 2011-06-14 | Amgen Inc. | Compounds and methods useful for treating asthma and allergic inflammation |
DK2229358T3 (da) | 2007-12-14 | 2011-07-04 | Pulmagen Therapeutics Asthma Ltd | Indoler og deres terapeutiske anvendelse |
MX2010007833A (es) | 2008-01-18 | 2010-08-11 | Oxagen Ltd | Compuestos que tienen actividad antagonista de crth2. |
US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
JP2011509991A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Crth2アンタゴニスト活性を有する化合物 |
EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
JPWO2010074244A1 (ja) * | 2008-12-25 | 2012-06-21 | 大正製薬株式会社 | イソキノリン誘導体 |
DK2433124T3 (en) * | 2009-05-19 | 2017-06-19 | Vivia Biotech Sl | PROCEDURES FOR PROVIDING PERSONALIZED MEDICAL EX VIVO TESTS FOR HEMATOLOGICAL NEOPLASMS |
KR101752932B1 (ko) * | 2009-07-06 | 2017-07-03 | 아스트라제네카 아베 | 4-(아세틸아미노))-3-[(4-클로로-페닐)티오]-2-메틸-1h-인돌-1-아세트산의 중간체 및 그의 제조 방법 |
WO2011100607A1 (en) | 2010-02-11 | 2011-08-18 | Vanderbilt University | Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as mglur4 allosteric potentiators, compounds, and methods of treating neurological dysfunction |
TWI562987B (en) | 2010-03-22 | 2016-12-21 | Actelion Pharmaceuticals Ltd | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators |
WO2011162274A1 (ja) | 2010-06-23 | 2011-12-29 | 大正製薬株式会社 | イソキノリン誘導体 |
EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
US9096595B2 (en) | 2011-04-14 | 2015-08-04 | Actelion Pharmaceuticals Ltd | 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators |
EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
WO2013088109A1 (en) | 2011-12-16 | 2013-06-20 | Oxagen Limited | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
EP2827952B1 (en) | 2012-03-21 | 2021-07-07 | The Trustees Of The University Of Pennsylvania | Composition for stimulating hair growth |
PE20161177A1 (es) | 2014-03-17 | 2016-11-18 | Actelion Pharmaceuticals Ltd | Derivados del acido acetico azaindol y su uso como moduladores del receptor de prostaglandina d2 |
MX2016011900A (es) | 2014-03-18 | 2016-12-05 | Actelion Pharmaceuticals Ltd | Derivados de acido azaindol-acetico y su uso como moduladores del receptor de prostaglandina d2. |
GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
TWI695831B (zh) | 2014-09-13 | 2020-06-11 | 香港商南北兄弟藥業投資有限公司 | Crth2拮抗劑化合物及其用途 |
CA2993972A1 (en) | 2015-07-30 | 2017-02-02 | The Trustees Of The University Of Pennsylvania | Single nucleotide polymorphic alleles of human dp-2 gene for detection of susceptibility to hair growth inhibition by pgd2 |
EA035752B1 (ru) | 2015-09-15 | 2020-08-05 | Идорсиа Фармасьютиклз Лтд | КРИСТАЛЛИЧЕСКАЯ ФОРМА (S)-2-(8-((5-ХЛОРПИРИМИДИН-2-ИЛ)(МЕТИЛ)-АМИНО)-2-ФТОР-6,7,8,9-ТЕТРАГИДРО-5Н-ПИРИДО[3,2-b]ИНДОЛ-5-ИЛ)УКСУСНОЙ КИСЛОТЫ И СОДЕРЖАЩИЕ ЕЁ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE790679A (fr) | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
JPH0615542B2 (ja) | 1986-07-22 | 1994-03-02 | 吉富製薬株式会社 | ピラゾロピリジン化合物 |
US5095031A (en) * | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
WO1993005020A1 (en) | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
FR2692574B1 (fr) | 1992-06-23 | 1995-06-23 | Sanofi Elf | Derives hydroxy-4 benzenethio, leur preparation ainsi que leur utilisation pour la preparation de derives aminoalkoxybenzenesulfonyles. |
JPH08507067A (ja) | 1993-02-24 | 1996-07-30 | メルク エンド カンパニー インコーポレーテッド | Hiv逆転写酵素阻害剤 |
US5486525A (en) | 1993-12-16 | 1996-01-23 | Abbott Laboratories | Platelet activating factor antagonists: imidazopyridine indoles |
US5567711A (en) | 1995-04-19 | 1996-10-22 | Abbott Laboratories | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists |
TW472045B (en) | 1996-09-25 | 2002-01-11 | Astra Ab | Protein kinase C inhibitor compounds, method for their preparation, pharmaceutical composition thereof and intermediate used for their preparation |
WO1999009007A1 (en) | 1997-08-21 | 1999-02-25 | American Home Products Corporation | Solid phase synthesis of 2,3-disubstituted indole compounds |
ATE239013T1 (de) | 1997-12-19 | 2003-05-15 | Lilly Co Eli | Hypoglykamische imidazoline derivate |
US6916841B2 (en) | 1998-02-25 | 2005-07-12 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
AU5886500A (en) | 1999-06-23 | 2001-01-09 | Sepracor, Inc. | Indolyl-benzimidazole antibacterials, and methods of use thereof |
AU7962200A (en) | 1999-10-29 | 2001-05-14 | Wakunaga Pharmaceutical Co., Ltd | Novel indole derivatives and drugs containing the same as the active ingredient |
BR0017038A (pt) | 1999-12-24 | 2003-01-07 | Aventis Pharma Ltd | Azaindóis |
CN1431999A (zh) * | 2000-05-31 | 2003-07-23 | 阿斯特拉曾尼卡有限公司 | 具有血管损伤活性的吲哚衍生物 |
US6878522B2 (en) * | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
TWI317634B (en) | 2001-12-13 | 2009-12-01 | Nat Health Research Institutes | Aroyl indoles compounds |
CA2473803A1 (en) | 2002-02-01 | 2003-08-07 | Robert Greenhouse | Substituted indoles as alpha-1 agonists |
SE0200356D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
JP4484108B2 (ja) | 2002-05-16 | 2010-06-16 | 塩野義製薬株式会社 | Pgd2受容体拮抗作用を有する化合物 |
SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0202463D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
EP1675826A1 (en) | 2003-10-14 | 2006-07-05 | Oxagen Limited | Compounds having crth2 antagonist activity |
SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
GB2422831A (en) | 2005-02-04 | 2006-08-09 | Oxagen Ltd | Pyrrolopyridines and their use in the treatment of diseases mediated by PGD2 at the CRTH2 receptor |
CN102558021A (zh) | 2006-05-26 | 2012-07-11 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
AU2007256564A1 (en) | 2006-06-08 | 2007-12-13 | Neurokey A/S | Use of cannabinoid receptor agonists as hypothermia inducing drugs for the treatment of ischemia |
AU2007264114A1 (en) | 2006-06-28 | 2008-01-03 | Sanofi-Aventis | New CXCR2 inhibitors |
-
2003
- 2003-08-18 SE SE0302232A patent/SE0302232D0/xx unknown
-
2004
- 2004-08-06 TW TW093123728A patent/TW200510303A/zh unknown
- 2004-08-16 EP EP04768065A patent/EP1656347B1/en not_active Not-in-force
- 2004-08-16 DK DK04768065.7T patent/DK1656347T3/da active
- 2004-08-16 WO PCT/GB2004/003502 patent/WO2005019171A1/en active Search and Examination
- 2004-08-16 AT AT04768065T patent/ATE484494T1/de active
- 2004-08-16 SA SA04250255A patent/SA04250255B1/ar unknown
- 2004-08-16 PT PT04768065T patent/PT1656347E/pt unknown
- 2004-08-16 MY MYPI20043328A patent/MY143367A/en unknown
- 2004-08-16 ES ES04768065T patent/ES2352201T3/es active Active
- 2004-08-16 JP JP2006523677A patent/JP4709758B2/ja not_active Expired - Fee Related
- 2004-08-16 SI SI200431554T patent/SI1656347T1/sl unknown
- 2004-08-16 DE DE602004029580T patent/DE602004029580D1/de active Active
- 2004-08-16 PL PL04768065T patent/PL1656347T3/pl unknown
- 2004-08-16 US US10/568,889 patent/US7709521B2/en not_active Expired - Fee Related
- 2004-08-17 UY UY28473A patent/UY28473A1/es unknown
- 2004-08-18 AR ARP040102959A patent/AR045462A1/es not_active Application Discontinuation
-
2010
- 2010-12-09 CY CY20101101133T patent/CY1110977T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2005019171A1 (en) | 2005-03-03 |
EP1656347A1 (en) | 2006-05-17 |
AR045462A1 (es) | 2005-10-26 |
SI1656347T1 (sl) | 2011-01-31 |
PT1656347E (pt) | 2010-12-09 |
SA04250255B1 (ar) | 2009-02-25 |
JP2007502804A (ja) | 2007-02-15 |
PL1656347T3 (pl) | 2011-02-28 |
CY1110977T1 (el) | 2015-06-11 |
DK1656347T3 (da) | 2011-01-10 |
JP4709758B2 (ja) | 2011-06-22 |
TW200510303A (en) | 2005-03-16 |
ATE484494T1 (de) | 2010-10-15 |
US20060264444A1 (en) | 2006-11-23 |
DE602004029580D1 (de) | 2010-11-25 |
EP1656347B1 (en) | 2010-10-13 |
MY143367A (en) | 2011-04-29 |
US7709521B2 (en) | 2010-05-04 |
ES2352201T3 (es) | 2011-02-16 |
UY28473A1 (es) | 2005-03-31 |
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