PT2250161E - Compostos tendo atividade antagonista de crth2 - Google Patents

Compostos tendo atividade antagonista de crth2 Download PDF

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Publication number
PT2250161E
PT2250161E PT97025985T PT09702598T PT2250161E PT 2250161 E PT2250161 E PT 2250161E PT 97025985 T PT97025985 T PT 97025985T PT 09702598 T PT09702598 T PT 09702598T PT 2250161 E PT2250161 E PT 2250161E
Authority
PT
Portugal
Prior art keywords
compounds
antagonist activity
crth2 antagonist
crth2
activity
Prior art date
Application number
PT97025985T
Other languages
English (en)
Inventor
Eric Roy Pettipher
Richard Edward Armer
Graham Michael Wynne
Mark Whittaker
Julia Vile
Frank Schroer
Original Assignee
Atopix Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0800874A external-priority patent/GB0800874D0/en
Priority claimed from GB0820526A external-priority patent/GB0820526D0/en
Application filed by Atopix Therapeutics Ltd filed Critical Atopix Therapeutics Ltd
Publication of PT2250161E publication Critical patent/PT2250161E/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P13/08—Drugs for disorders of the urinary system of the prostate
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
PT97025985T 2008-01-18 2009-01-19 Compostos tendo atividade antagonista de crth2 PT2250161E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0800874A GB0800874D0 (en) 2008-01-18 2008-01-18 Compounds having CRTH2 antagonist activity
GB0820526A GB0820526D0 (en) 2008-11-10 2008-11-10 Compounds having crth2 antagonist activity

Publications (1)

Publication Number Publication Date
PT2250161E true PT2250161E (pt) 2014-01-21

Family

ID=40473418

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97025985T PT2250161E (pt) 2008-01-18 2009-01-19 Compostos tendo atividade antagonista de crth2

Country Status (25)

Country Link
US (1) US20090186923A1 (pt)
EP (1) EP2250161B1 (pt)
JP (2) JP2011509988A (pt)
KR (1) KR101644170B1 (pt)
CN (1) CN101932571B (pt)
AU (1) AU2009204700B2 (pt)
BR (1) BRPI0906786B1 (pt)
CA (1) CA2712017C (pt)
CY (1) CY1114748T1 (pt)
DK (1) DK2250161T3 (pt)
ES (1) ES2442717T3 (pt)
HK (1) HK1145175A1 (pt)
HR (1) HRP20140045T1 (pt)
IL (1) IL206959A (pt)
MA (1) MA32075B1 (pt)
MX (1) MX2010007833A (pt)
MY (1) MY155133A (pt)
NZ (1) NZ587251A (pt)
PL (1) PL2250161T3 (pt)
PT (1) PT2250161E (pt)
RS (1) RS53142B (pt)
RU (1) RU2503672C2 (pt)
SI (1) SI2250161T1 (pt)
WO (1) WO2009090414A1 (pt)
ZA (1) ZA201005799B (pt)

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WO2009093029A1 (en) * 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
JP2011509990A (ja) * 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
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GB2465062B (en) * 2008-11-06 2011-04-13 Amira Pharmaceuticals Inc Cycloalkane(B)azaindole antagonists of prostaglandin D2 receptors
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KR20120038544A (ko) * 2009-07-31 2012-04-23 판미라 파마슈티칼스, 엘엘씨 Ｄｐ2 수용체 길항제의 안과용 약학 조성물
WO2011017201A2 (en) * 2009-08-05 2011-02-10 Amira Pharmaceuticals, Inc. Dp2 antagonist and uses thereof
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KR101444572B1 (ko) 2010-03-22 2014-09-24 액테리온 파마슈티칼 리미티드 3-(헤테로아릴-아미노)-1,2,3,4-테트라히드로-9ｈ-카르바졸 유도체 및 이의 프로스타글란딘 ｄ2 수용체 조절제로서의 용도
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