JP4651814B2 - 血中のフィブリノーゲン・レベルを低下させるためのラクトバシラスの使用 - Google Patents

血中のフィブリノーゲン・レベルを低下させるためのラクトバシラスの使用 Download PDF

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Publication number
JP4651814B2
JP4651814B2 JP2000506312A JP2000506312A JP4651814B2 JP 4651814 B2 JP4651814 B2 JP 4651814B2 JP 2000506312 A JP2000506312 A JP 2000506312A JP 2000506312 A JP2000506312 A JP 2000506312A JP 4651814 B2 JP4651814 B2 JP 4651814B2
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Japan
Prior art keywords
lactobacillus
levels
fibrinogen
cholesterol
fibrinogen levels
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Expired - Lifetime
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JP2000506312A
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Japanese (ja)
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JP2001512747A (ja
Inventor
ハンナ ブコウスカ
マリー−ルイーズ ヨハンソン
マレク ナルスゼヴィッチ
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プロビ エービー
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y10S435/856—Lactobacillus casei
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/853—Lactobacillus
    • Y10S435/857—Lactobacillus plantarum

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2000506312A 1997-08-05 1998-07-30 血中のフィブリノーゲン・レベルを低下させるためのラクトバシラスの使用 Expired - Lifetime JP4651814B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9702860A SE510753C2 (sv) 1997-08-05 1997-08-05 Användning av en stam av Lactobacillus för tillverkning av ett läkemedel för reduktion av fibrinogenhalten i blod
SE9702860-9 1997-08-05
PCT/SE1998/001423 WO1999007827A1 (en) 1997-08-05 1998-07-30 Use of lactobacillus for reduction of the fibrinogen level in blood

Publications (2)

Publication Number Publication Date
JP2001512747A JP2001512747A (ja) 2001-08-28
JP4651814B2 true JP4651814B2 (ja) 2011-03-16

Family

ID=20407874

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000506312A Expired - Lifetime JP4651814B2 (ja) 1997-08-05 1998-07-30 血中のフィブリノーゲン・レベルを低下させるためのラクトバシラスの使用

Country Status (19)

Country Link
US (1) US6214336B1 (pt)
EP (1) EP0990024B1 (pt)
JP (1) JP4651814B2 (pt)
KR (1) KR100517755B1 (pt)
CN (1) CN1142995C (pt)
AR (1) AR016798A1 (pt)
AT (1) ATE326524T1 (pt)
AU (1) AU729413B2 (pt)
BR (1) BR9811825A (pt)
CA (1) CA2297023C (pt)
DE (1) DE69834560T2 (pt)
ES (1) ES2259457T3 (pt)
IL (1) IL134113A0 (pt)
NO (1) NO324881B1 (pt)
NZ (1) NZ502610A (pt)
PL (1) PL194697B1 (pt)
SE (1) SE510753C2 (pt)
WO (1) WO1999007827A1 (pt)
ZA (1) ZA986769B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU764011B2 (en) 1998-10-01 2003-08-07 Probi Ab Reduction of oxidative stress factors
JP4193269B2 (ja) * 1999-03-04 2008-12-10 ビーエイチピーエイチ カンパニーリミテッド 新規な生体浄化活性型乳酸菌製剤
SE523771C2 (sv) * 1999-05-21 2004-05-18 Probi Ab Sportdryck innehållande mikronäringsämnen i kombination med levande laktobaciller
AUPR101600A0 (en) * 2000-10-25 2000-11-16 Atheromastat Pty Ltd Compositions and methods for diagnosis and treatment of cardiovascular disorders
SE0004124D0 (sv) * 2000-11-10 2000-11-10 Probi Ab New use
GB0124580D0 (en) * 2001-10-12 2001-12-05 Univ Reading New composition
KR20030033950A (ko) * 2001-10-20 2003-05-01 주식회사 알엔에이 유산균 세포질 분획물 또는 유산균 파쇄물을 유효성분으로포함하는 동맥경화 억제제
FR2831395B1 (fr) * 2001-10-25 2004-06-11 Triballat Laiteries Procede de fabrication de produits fermentes a base de soja, produits fermentes obtenus par ce procede et ferments correspondants
TWI241912B (en) * 2002-10-30 2005-10-21 Food Industry Res & Dev Inst Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol
SE527555C2 (sv) * 2003-04-04 2006-04-11 Probi Ab Anti-inflammatorisk komposition innehållande tannasproducerande Lactobacillusstammar
CN1207382C (zh) * 2003-04-11 2005-06-22 上海光明乳业股份有限公司 植物乳杆菌st－iii菌株及其在调节血脂方面的应用
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US7001756B1 (en) * 2004-02-19 2006-02-21 Genmont Biotech Inc. Microorganism strain of GM-020 of Lactobacillus rhamnosus and its use for treating obesity
GB0424552D0 (en) * 2004-11-05 2004-12-08 Cambridge Theranostics Ltd Methods and means
AU2006253006B8 (en) 2005-05-31 2011-09-15 Alimentary Health Ltd Feline probiotic Lactobacilli
BRPI0611492B1 (pt) 2005-05-31 2021-10-13 Mars, Incorporated Bifidobactéria probiótica felina
US20080254011A1 (en) * 2007-04-11 2008-10-16 Peter Rothschild Use of selected lactic acid bacteria for reducing atherosclerosis
KR100909586B1 (ko) * 2007-06-01 2009-07-27 신현길 혈중 콜레스테롤 농도 저하에 효과적인 유산균 및 이들의혼합균주
SE532899C2 (sv) * 2007-06-08 2010-05-04 Probi Ab Förfarande genom fermentering med Lactobacillus plantarum för tillhandahållande av en insulinsvarsreducerande produkt och dess användning farmaceutiskt eller i livsmedel
JP5469873B2 (ja) * 2008-03-11 2014-04-16 株式会社日立製作所 回転電機
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
JP5140791B2 (ja) * 2008-11-27 2013-02-13 森下仁丹株式会社 乳酸菌含有血中ホモシステイン低減剤
US9474773B2 (en) 2009-02-18 2016-10-25 University Of Florida Research Foundation, Inc. Lactobacillus supplement for alleviating type 1 diabetes
ES2729765T3 (es) * 2009-06-19 2019-11-06 Dupont Nutrition Biosci Aps Bifidobacterias para el tratamiento de la insuficiencia cardíaca congestiva
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
CN102031229B (zh) * 2009-09-24 2012-05-30 家医国际生化股份有限公司 具有肠胃道吸附能力及排除胆固醇能力的植物乳杆菌
PL2521769T3 (pl) * 2010-01-08 2017-01-31 Gervais Danone Sa Pałeczki kwasu mlekowego z działaniem przeciwutleniającym
GB201319540D0 (en) * 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition
GB201319538D0 (en) 2013-11-05 2013-12-18 Optibiotix Health Ltd Composition
GB201709763D0 (en) * 2017-06-19 2017-08-02 Probi Ab Biological materials and methods
CN110786435B (zh) * 2019-11-19 2022-08-23 四川农业大学 产高活性纤溶酶原激活剂的植物乳杆菌及用其发酵的果蔬汁饮料

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63139129A (ja) * 1986-12-01 1988-06-10 Yakult Honsha Co Ltd 血圧降下剤
JPH04208226A (ja) * 1990-11-30 1992-07-29 Yakult Honsha Co Ltd 脂質代謝改善剤
JPH04264034A (ja) * 1991-02-18 1992-09-18 Snow Brand Milk Prod Co Ltd 生体内過酸化脂質抑制剤

Family Cites Families (7)

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JP2676250B2 (ja) * 1989-03-20 1997-11-12 株式会社ヤクルト本社 血圧降下剤およびその製造法
JPH0525055A (ja) * 1991-07-22 1993-02-02 Yakult Honsha Co Ltd 血圧降下剤
SE469875C (sv) * 1991-07-25 1997-02-05 Probi Ab Stam av tarmkoloniserande Lactobacillus samt komposition för profylax eller behandling av infektioner i magtarmkanalen
JPH06116155A (ja) * 1992-10-08 1994-04-26 Yakult Honsha Co Ltd 血清コレステロール低下剤
JP2801479B2 (ja) * 1992-10-09 1998-09-21 株式会社トクヤマ 補綴材料の製造方法
JP2992945B2 (ja) * 1994-03-11 1999-12-20 カルピス株式会社 ラクトバチルス・アシドフィルス乳酸菌
JPH08208512A (ja) * 1995-02-03 1996-08-13 Nippon Chem Res Kk 血栓形成阻害剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63139129A (ja) * 1986-12-01 1988-06-10 Yakult Honsha Co Ltd 血圧降下剤
JPH04208226A (ja) * 1990-11-30 1992-07-29 Yakult Honsha Co Ltd 脂質代謝改善剤
JPH04264034A (ja) * 1991-02-18 1992-09-18 Snow Brand Milk Prod Co Ltd 生体内過酸化脂質抑制剤

Also Published As

Publication number Publication date
IL134113A0 (en) 2001-04-30
DE69834560T2 (de) 2006-11-02
EP0990024A1 (en) 2000-04-05
AU8372698A (en) 1999-03-01
SE510753C2 (sv) 1999-06-21
NO20000268L (no) 2000-01-19
EP0990024B1 (en) 2006-05-17
AR016798A1 (es) 2001-08-01
DE69834560D1 (de) 2006-06-22
KR20010022617A (ko) 2001-03-26
US6214336B1 (en) 2001-04-10
BR9811825A (pt) 2000-08-15
CN1142995C (zh) 2004-03-24
JP2001512747A (ja) 2001-08-28
ES2259457T3 (es) 2006-10-01
NO20000268D0 (no) 2000-01-19
CN1265141A (zh) 2000-08-30
NO324881B1 (no) 2007-12-27
NZ502610A (en) 2000-12-22
SE9702860D0 (sv) 1997-08-05
CA2297023C (en) 2010-03-30
PL194697B1 (pl) 2007-06-29
AU729413B2 (en) 2001-02-01
WO1999007827A1 (en) 1999-02-18
ZA986769B (en) 1999-02-02
CA2297023A1 (en) 1999-02-18
KR100517755B1 (ko) 2005-09-30
SE9702860L (sv) 1999-02-06
PL338578A1 (en) 2000-11-06
ATE326524T1 (de) 2006-06-15

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