JP4477355B2 - 吸入のために流体を噴霧するためのデバイスおよび方法 - Google Patents

吸入のために流体を噴霧するためのデバイスおよび方法 Download PDF

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Publication number
JP4477355B2
JP4477355B2 JP2003557645A JP2003557645A JP4477355B2 JP 4477355 B2 JP4477355 B2 JP 4477355B2 JP 2003557645 A JP2003557645 A JP 2003557645A JP 2003557645 A JP2003557645 A JP 2003557645A JP 4477355 B2 JP4477355 B2 JP 4477355B2
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Prior art keywords
reservoir
plunger
dose
nebulizer
vial
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Expired - Lifetime
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JP2003557645A
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Japanese (ja)
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JP2005514974A (ja
JP2005514974A5 (https=
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ラジャン パテル，
マイケル エー． クリモウィッズ，
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エアロジェン，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0085—Inhalators using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
    • B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0024—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
JP2003557645A 2002-01-07 2003-01-07 吸入のために流体を噴霧するためのデバイスおよび方法 Expired - Lifetime JP4477355B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34678902P 2002-01-07 2002-01-07
US40345402P 2002-08-13 2002-08-13
PCT/US2003/000504 WO2003057291A1 (en) 2002-01-07 2003-01-07 Devices and methods for nebulizing fluids for inhalation

Publications (3)

Publication Number Publication Date
JP2005514974A JP2005514974A (ja) 2005-05-26
JP2005514974A5 JP2005514974A5 (https=) 2006-02-16
JP4477355B2 true JP4477355B2 (ja) 2010-06-09

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JP2003557645A Expired - Lifetime JP4477355B2 (ja) 2002-01-07 2003-01-07 吸入のために流体を噴霧するためのデバイスおよび方法

Country Status (7)

Country Link
US (2) US7360536B2 (https=)
EP (1) EP1471960B1 (https=)
JP (1) JP4477355B2 (https=)
AU (1) AU2003202925B2 (https=)
CA (1) CA2472644C (https=)
MX (1) MXPA04006629A (https=)
WO (1) WO2003057291A1 (https=)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US6540154B1 (en) 1991-04-24 2003-04-01 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US7600511B2 (en) 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US6948491B2 (en) 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
MXPA02010884A (es) 2000-05-05 2003-03-27 Aerogen Ireland Ltd Aparato y metodo para el suministro de medicamentos al sistema respiratorio.
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US7100600B2 (en) 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US6732944B2 (en) 2001-05-02 2004-05-11 Aerogen, Inc. Base isolated nebulizing device and methods
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
EP1471960B1 (en) * 2002-01-07 2019-03-13 Novartis AG Devices for nebulizing fluids for inhalation
EP1474196B1 (en) 2002-01-15 2016-08-17 Novartis AG Methods and systems for operating an aerosol generator
AU2003256253A1 (en) 2002-05-20 2003-12-02 Aerogen, Inc. Aerosol for medical treatment and methods
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US20070235555A1 (en) * 2006-04-11 2007-10-11 Helf Thomas A Electronic aerosol device
GB0402697D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402690D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402694D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402693D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402695D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A metering pump system
GB0402691D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
GB0402692D0 (en) * 2004-02-06 2004-03-10 Glaxo Group Ltd A fluid dispenser
CN2719043Y (zh) 2004-04-14 2005-08-24 韩力 雾化电子烟
US7267121B2 (en) 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
US7290541B2 (en) 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
DE102005006374B3 (de) * 2005-02-11 2006-07-20 Pari GmbH Spezialisten für effektive Inhalation Aerosolerzeugungsvorrichtung und Inhalationstherapiegerät mit einer derartigen Vorrichtung
BRPI0611198B1 (pt) 2005-05-25 2018-02-06 Aerogen, Inc. Vibration systems and methods
DE102005038619A1 (de) 2005-08-16 2007-02-22 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments
EP2037999B1 (en) 2006-07-07 2016-12-28 Proteus Digital Health, Inc. Smart parenteral administration system
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
DE102007056462B4 (de) * 2007-11-23 2011-10-27 Pari Pharma Gmbh Einwegampulle für eine Vorrichtung zur Erzeugung von Aerosolen
US8276587B2 (en) * 2008-02-15 2012-10-02 Tsi, Incorporated Automated qualitative mask fit tester
US9278048B2 (en) * 2009-05-06 2016-03-08 Baxter International, Inc. Pharmaceutical product and method of use
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
US8950394B2 (en) 2010-01-12 2015-02-10 Dance Biopharm Inc. Preservative-free single dose inhaler systems
US10525214B2 (en) * 2010-01-12 2020-01-07 Dance Biopharm Inc. Preservative-free single dose inhaler system
KR20120114368A (ko) 2010-02-01 2012-10-16 프로테우스 디지털 헬스, 인코포레이티드 양 손목을 이용한 데이터 수집 시스템
KR101798128B1 (ko) 2010-02-01 2017-11-16 프로테우스 디지털 헬스, 인코포레이티드 데이터 수집 시스템
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
WO2012026963A2 (en) 2010-08-23 2012-03-01 Darren Rubin Systems and methods of aerosol delivery with airflow regulation
WO2012046220A1 (en) 2010-10-04 2012-04-12 Stamford Devices Limited An aerosol generator
US20130269694A1 (en) * 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Inhaler controlled by mobile device
EP2735328A1 (en) * 2012-11-27 2014-05-28 PARI Pharma GmbH Fluid reservoir for an aerosol generation device, combination of fluid reservoir and primary fluid package, and aerosol generation device for use with the fluid reservoir
JP6434973B2 (ja) 2013-07-24 2018-12-05 スタムフォード・ディバイセズ・リミテッド 噴霧器振動開口板駆動周波数の制御および監視
US10610651B2 (en) 2014-06-09 2020-04-07 Aerami Therapeutics, Inc. Self-puncturing liquid drug cartridges and associated dispenser
CN106999681B (zh) 2014-08-28 2021-02-02 诺顿（沃特福特）有限公司 吸入器的依从性辅助模块
US20160158471A1 (en) * 2014-12-05 2016-06-09 Dance Biopharm, Inc. Integration of glucose data to adjust inhaled insulin dose
WO2016138413A1 (en) 2015-02-27 2016-09-01 Board Of Regents, The University Of Texas System Polypeptide therapeutics and uses thereof
US11517525B2 (en) * 2015-09-18 2022-12-06 Hikma Pharmaceuticals Usa Inc. Epinephrine spray formulations
CN108525082B (zh) * 2017-03-31 2020-06-09 纳智源科技（唐山）有限责任公司 具有吸药量监测功能的雾化器及吸药量监测系统
JP7227163B2 (ja) 2017-06-10 2023-02-21 アイノビア，インコーポレイティド 流体を取扱い、目に流体を送出するための方法および装置
KR102055609B1 (ko) * 2017-06-13 2019-12-13 동국대학교 경주캠퍼스 산학협력단 약액전달장치
US11000068B2 (en) 2017-06-20 2021-05-11 Cascadia Technologies, LLC Aerosol inhalant producing device with measurable dose and/or other features
AU2019339260B2 (en) 2018-09-10 2025-06-26 Rein Therapeutics, Inc. Modified peptide fragments of Cav-1 protein and the use thereof in the treatment of fibrosis
US11344686B2 (en) * 2018-12-21 2022-05-31 Bn Intellectual Properties, Inc. Method of respiratory system treatment
CN109568738A (zh) * 2019-02-02 2019-04-05 上海方予健康医药科技有限公司 雾化给药装置及其系统
US11135379B2 (en) * 2019-02-15 2021-10-05 Bn Intellectual Properties, Inc. Method of delivering pharmaceutical products
WO2020185826A1 (en) 2019-03-11 2020-09-17 Lung Therapeutics, Inc. Compositions and methods for protecting type 2 alveolar epithelial cells (aec2)
US20210077753A1 (en) * 2019-04-01 2021-03-18 Bn Intellectual Properties, Inc. Nebulizer delivery systems and methods
US12396480B2 (en) * 2019-05-22 2025-08-26 Rai Strategic Holdings, Inc. Reservoir configuration for aerosol delivery device
WO2021119513A1 (en) 2019-12-11 2021-06-17 Eyenovia, Inc. Systems and devices for delivering fluids to the eye and methods of use
US10806868B1 (en) 2020-02-03 2020-10-20 Monq, Llc Mesh nebulizer systems
US11529311B2 (en) * 2021-01-28 2022-12-20 Bn Intellectual Properties, Inc. Method of using nebulized alcohol for analgesia
EP4295879A1 (de) * 2022-06-21 2023-12-27 HATCHMORE Labs GmbH Nasenapplikator
CN117413977A (zh) * 2022-07-11 2024-01-19 深圳市卓力能技术有限公司 气溶胶产生装置
CN120346407B (zh) * 2025-06-12 2025-10-28 合肥力成药业有限公司 一种气溶胶吸入装置

Family Cites Families (462)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US550315A (en) 1895-11-26 Frank napoleon allen
US2735427A (en) * 1956-02-21 Hypodermic syringe
US809159A (en) 1905-09-30 1906-01-02 Richard M Willis Dispensing bottle or jar.
US1680616A (en) 1922-06-06 1928-08-14 Horst Friedrich Wilhelm Sealed package
US2022520A (en) 1934-07-07 1935-11-26 Parsons Ammonia Company Inc Bottle
US2101304A (en) 1936-06-05 1937-12-07 Sheaffer W A Pen Co Fountain pen
US2187528A (en) 1937-06-07 1940-01-16 Russell T Wing Fountain pen
US2158615A (en) 1937-07-26 1939-05-16 Sheaffer W A Pen Co Fountain pen
US2266706A (en) 1938-08-06 1941-12-16 Stanley L Fox Nasal atomizing inhaler and dropper
BE436027A (https=) 1939-01-06
US2292381A (en) 1940-12-24 1942-08-11 Esterbrook Steel Pen Mfg Co Fountain pen feed
US2283333A (en) 1941-05-22 1942-05-19 Sheaffer W A Pen Co Fountain pen
US2383098A (en) 1942-07-21 1945-08-21 Jr Frank H Wheaton Double-mouthed bottle
US2375770A (en) 1943-11-19 1945-05-15 Arthur O Dahiberg Fountain pen
US2430023A (en) 1944-01-27 1947-11-04 Esterbrook Pen Co Writing implement
NL63900C (https=) 1944-04-10
US2404063A (en) 1944-04-27 1946-07-16 Parker Pen Co Fountain pen
US2521657A (en) 1944-07-07 1950-09-05 Scripto Inc Fountain pen
US2512004A (en) 1945-03-05 1950-06-20 Russell T Wing Fountain pen
US2474996A (en) 1945-10-12 1949-07-05 Sheaffer W A Pen Co Fountain pen
NL68028C (https=) 1946-06-08
US2705007A (en) 1951-09-10 1955-03-29 Louis P Gerber Inhaler
US2764979A (en) 1953-04-09 1956-10-02 Henderson Edward Medicament dispensing unit
US2764946A (en) 1954-04-05 1956-10-02 Scognamillo Frank Rotary pump
US2779623A (en) 1954-09-10 1957-01-29 Bernard J Eisenkraft Electromechanical atomizer
US2935970A (en) 1955-03-23 1960-05-10 Sapphire Products Inc Fountain pen ink reservoir
DE1103522B (de) 1957-10-24 1961-03-30 Transform Roentgen Matern Veb Abatmungseinrichtung fuer mittels Ultraschall erzeugte Aerosole
US3103310A (en) 1961-11-09 1963-09-10 Exxon Research Engineering Co Sonic atomizer for liquids
GB973458A (en) 1962-10-16 1964-10-28 Exxon Research Engineering Co Improvements in or relating to methods and apparatus for atomising liquids
FR1449600A (fr) 1964-09-14 1966-05-06 Fr Des Laboratoires Labaz Soc Perfectionnements aux flacons en matière souple, notamment pour produits médicamenteux
US3680954A (en) 1965-04-30 1972-08-01 Eastman Kodak Co Electrography
DE1461628A1 (de) 1965-04-30 1969-03-27 Montblanc Simplo Gmbh Tintenleiter fuer Fuellfederhalter
US3353537A (en) * 1965-08-11 1967-11-21 George W Knox Automatic multi-dosage inoculating instrument
DE1654994A1 (de) 1967-02-17 1970-03-26 Neff Werke Carl Neff Gmbh Bret Bodenfreie Kochgeraete,insbesondere fuer Grosskuechen
US3550864A (en) 1967-12-11 1970-12-29 Borg Warner High efficiency flashing nozzle
US3561444A (en) 1968-05-22 1971-02-09 Bio Logics Inc Ultrasonic drug nebulizer
US3515348A (en) 1968-07-22 1970-06-02 Lewbill Ind Inc Mist-producing device
US3558052A (en) 1968-10-31 1971-01-26 F I N D Inc Method and apparatus for spraying electrostatic dry powder
US3563415A (en) 1969-06-04 1971-02-16 Multi Drop Adapter Corp Multidrop adapter
US3719328A (en) 1970-10-22 1973-03-06 C Hindman Adjustable spray head
US3690317A (en) * 1970-10-29 1972-09-12 Bendix Corp Sonic nebulizer
US3738574A (en) 1971-06-15 1973-06-12 Siemens Ag Apparatus for atomizing fluids with a piezoelectrically stimulated oscillator system
NO134730L (https=) 1971-07-19 1900-01-01
US3838686A (en) 1971-10-14 1974-10-01 G Szekely Aerosol apparatus for inhalation therapy
US3983740A (en) 1971-12-07 1976-10-05 Societe Grenobloise D'etudes Et D'applications Hydrauliques (Sogreah) Method and apparatus for forming a stream of identical drops at very high speed
US3790079A (en) 1972-06-05 1974-02-05 Rnb Ass Inc Method and apparatus for generating monodisperse aerosol
US3778786A (en) 1972-06-28 1973-12-11 Nasa Data storage, image tube type
US3812854A (en) 1972-10-20 1974-05-28 A Michaels Ultrasonic nebulizer
US3842833A (en) * 1972-12-11 1974-10-22 Ims Ltd Neb-u-pack
US3858739A (en) * 1973-03-05 1975-01-07 Barnes Hind Diagnostics Inc Breakaway neck container with integral cap
FR2224175B1 (https=) 1973-04-04 1978-04-14 Isf Spa
AT323114B (de) 1973-05-07 1975-06-25 Voest Ag Verfahren zum prillen
US3804329A (en) 1973-07-27 1974-04-16 J Martner Ultrasonic generator and atomizer apparatus and method
US3903884A (en) 1973-08-15 1975-09-09 Becton Dickinson Co Manifold nebulizer system
DE2361781A1 (de) 1973-12-12 1975-06-19 Philips Patentverwaltung Schreibwerk zum schreiben mit fluessiger farbe
US3865106A (en) 1974-03-18 1975-02-11 Bernard P Palush Positive pressure breathing circuit
US3951313A (en) 1974-06-05 1976-04-20 Becton, Dickinson And Company Reservoir with prepacked diluent
US3993223A (en) 1974-07-25 1976-11-23 American Home Products Corporation Dispensing container
US3908654A (en) 1974-08-02 1975-09-30 Rit Rech Ind Therapeut Dispensing package for a dry biological and a liquid diluent
DE2445791C2 (de) 1974-09-25 1984-04-19 Siemens AG, 1000 Berlin und 8000 München Ultraschall-Flüssigkeitszerstäuber
AR205589A1 (es) 1974-10-09 1976-05-14 Reckitt & Colmann Prod Ltd Dispositivo introductor de una composicion acuosa en una cavidad corporal
US3958249A (en) 1974-12-18 1976-05-18 International Business Machines Corporation Ink jet drop generator
US4059384A (en) 1975-01-20 1977-11-22 Misto2 Gen Equipment Co. Two-step injection molding
AT337345B (de) 1975-02-05 1977-06-27 Draegerwerk Ag Gerat zur unterstutzung der atmung und/oder kunstlichen beatmung zur humanen verwendung
US4005435A (en) 1975-05-15 1977-01-25 Burroughs Corporation Liquid jet droplet generator
AU67278S (en) 1975-06-04 1975-11-12 Warner Lambert Co Bottle
DE2537765B2 (de) 1975-08-25 1981-04-09 Siemens AG, 1000 Berlin und 8000 München Medizinisches Inhalationsgerät zur Behandlung von Krankheiten der Atmungswege
GB1571304A (en) 1976-02-24 1980-07-16 Lucas Industries Ltd Drive circuit for a piezo electric crystal
US4094317A (en) 1976-06-11 1978-06-13 Wasnich Richard D Nebulization system
US4121583A (en) 1976-07-13 1978-10-24 Wen Yuan Chen Method and apparatus for alleviating asthma attacks
US4076021A (en) 1976-07-28 1978-02-28 Thompson Harris A Positive pressure respiratory apparatus
US4083368A (en) 1976-09-01 1978-04-11 Freezer Winthrop J Inhaler
JPS5364830A (en) 1976-11-19 1978-06-09 Howa Sangyo Kk Air inlet and outlet device of onnvehicle refrigerator
USD249958S (en) 1977-01-10 1978-10-17 Warner-Lambert Company Dispensing container for pharmaceutical diluents
US4106503A (en) 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
US4159803A (en) 1977-03-31 1979-07-03 MistO2 Gen Equipment Company Chamber for ultrasonic aerosol generation
US4113809A (en) 1977-04-04 1978-09-12 Champion Spark Plug Company Hand held ultrasonic nebulizer
US4101041A (en) 1977-08-01 1978-07-18 Becton, Dickinson And Company Prefillable, hermetically sealed container adapted for use with a humidifier or nebulizer head
US4268460A (en) 1977-12-12 1981-05-19 Warner-Lambert Company Nebulizer
USD259213S (en) 1978-03-13 1981-05-12 Automatic Liquid Packaging, Inc. Vial suitable for pharmaceuticals
DE2811248C3 (de) 1978-03-15 1981-11-26 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Flüssigkeitszerstäuber
US4298045A (en) 1978-04-17 1981-11-03 Automatic Liquid Packaging, Inc. Dispensing container with plural removable closure means unitary therewith
US4338576A (en) 1978-07-26 1982-07-06 Tdk Electronics Co., Ltd. Ultrasonic atomizer unit utilizing shielded and grounded elements
US4210155A (en) 1978-08-03 1980-07-01 Jerry Grimes Inspirational inhalation spirometer apparatus
DE2843756C3 (de) 1978-10-06 1988-05-26 Klarhorst, Günter, 4800 Bielefeld Vorrichtung zum Erzeugen eines Aerosols
US4240081A (en) 1978-10-13 1980-12-16 Dennison Manufacturing Company Ink jet printing
DE2849493C2 (de) 1978-11-15 1982-01-14 Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems In der Hand zu haltender Aerosolspender
DE2854841C2 (de) 1978-12-19 1981-03-26 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Flüssigkeitszerstäuber, vorzugsweise Inhalationsgerät
JPS5848225B2 (ja) * 1979-01-09 1983-10-27 オムロン株式会社 超音波液体霧化装置の霧化量制御方式
DE2907348A1 (de) 1979-02-24 1980-09-04 Boehringer Sohn Ingelheim Verbesserte inhalationsgeraete
US4207990A (en) 1979-05-03 1980-06-17 Automatic Liquid Packaging, Inc. Hermetically sealed container with plural access ports
US4226236A (en) 1979-05-07 1980-10-07 Abbott Laboratories Prefilled, vented two-compartment syringe
US4248227A (en) 1979-05-14 1981-02-03 Bristol-Myers Company Fluid unit dispensing device
US4240417A (en) 1979-06-13 1980-12-23 Holever Bernard K Tracheal tube adapter for ventilating apparatus
DE7917568U1 (de) 1979-06-19 1979-09-20 Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart Inhalationsgeraet
JPS5689569A (en) 1979-12-19 1981-07-20 Canon Inc Ink jet recording head
US4368850A (en) 1980-01-17 1983-01-18 George Szekely Dry aerosol generator
DE3010178C2 (de) 1980-03-17 1985-10-03 Kraftwerk Union AG, 4330 Mülheim Mit einem Schnellschlußventil ausgerüstete Schlitzdüse zur Herbeiführung impulsartiger Gasströmungen
NL189237C (nl) 1980-04-12 1993-02-16 Battelle Institut E V Inrichting voor het verstuiven van vloeistoffen.
JPS604714Y2 (ja) 1980-05-08 1985-02-12 スズキ株式会社 搬送装置
US4336544A (en) 1980-08-18 1982-06-22 Hewlett-Packard Company Method and apparatus for drop-on-demand ink jet printing
JPS5750006U (https=) * 1980-09-05 1982-03-20
JPS5929118B2 (ja) 1980-09-19 1984-07-18 セイコーエプソン株式会社 パラジウム・ニツケル合金メツキ液
US4465234A (en) 1980-10-06 1984-08-14 Matsushita Electric Industrial Co., Ltd. Liquid atomizer including vibrator
US4474251A (en) 1980-12-12 1984-10-02 Hydronautics, Incorporated Enhancing liquid jet erosion
US4389071A (en) 1980-12-12 1983-06-21 Hydronautics, Inc. Enhancing liquid jet erosion
JPS57105608U (https=) 1980-12-20 1982-06-29
US4374707A (en) 1981-03-19 1983-02-22 Xerox Corporation Orifice plate for ink jet printing machines
US5862802A (en) 1981-04-03 1999-01-26 Forrest M. Bird Ventilator having an oscillatory inspiratory phase and method
US4454877A (en) 1981-05-26 1984-06-19 Andrew Boettner Portable nebulizer or mist producing device
NL8202263A (nl) 1981-06-06 1983-01-03 Rowenta Werke Gmbh Ultrasonore respirator.
US4408719A (en) 1981-06-17 1983-10-11 Last Anthony J Sonic liquid atomizer
US4475113A (en) 1981-06-18 1984-10-02 International Business Machines Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids
JPS5861857U (ja) 1981-09-26 1983-04-26 ナショナル住宅産業株式会社 ル−バ取付構造
JPS5861857A (ja) 1981-10-09 1983-04-13 Matsushita Electric Works Ltd 液体噴霧器
AU553251B2 (en) 1981-10-15 1986-07-10 Matsushita Electric Industrial Co., Ltd. Arrangement for ejecting liquid
US4474326A (en) 1981-11-24 1984-10-02 Tdk Electronics Co., Ltd. Ultrasonic atomizing device
CA1206996A (en) 1982-01-18 1986-07-02 Naoyoshi Maehara Ultrasonic liquid ejecting apparatus
US5073484A (en) 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
JPS58139757U (ja) 1982-03-15 1983-09-20 株式会社日立製作所 リングトリツプ回路
DE3311956A1 (de) 1982-03-31 1983-10-13 Ricoh Co., Ltd., Tokyo Farbstrahl-druckerkopf
US4823784A (en) * 1982-04-30 1989-04-25 Cadema Medical Products, Inc. Aerosol inhalation apparatus
US4566452A (en) 1982-07-12 1986-01-28 American Hospital Supply Corporation Nebulizer
JPS5912775A (ja) 1982-07-14 1984-01-23 Matsushita Electric Ind Co Ltd 霧化ポンプユニツト
DE3229921A1 (de) 1982-08-11 1984-02-16 Linde Ag, 6200 Wiesbaden Verfahren zum gleichzeitigen befuellen von mehreren mit acetylen gefuellten flaschen mit loesungsmitteln
US5512329A (en) 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5217492A (en) 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US5258041A (en) 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US4973493A (en) 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US4722906A (en) 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
IT1156090B (it) 1982-10-26 1987-01-28 Olivetti & Co Spa Metodo e dispositivo di stampa a getto d inchiostro
US4512341A (en) 1982-11-22 1985-04-23 Lester Victor E Nebulizer with capillary feed
US4632311A (en) 1982-12-20 1986-12-30 Matsushita Electric Industrial Co., Ltd. Atomizing apparatus employing a capacitive piezoelectric transducer
JPS59142163A (ja) 1983-02-04 1984-08-15 Canon Inc ドツト式プリンタおよびその印字方法
DE3320441A1 (de) 1983-06-06 1984-12-06 Siemens AG, 1000 Berlin und 8000 München Mit fluessigkeitstroepfchen arbeitendes schreibgeraet mit an beiden enden starr mit einer duesenplatte verbundenen stabfoermigen piezoelektrischen wandlern
JPS607721A (ja) 1983-06-28 1985-01-16 Toshiba Corp 化合物半導体装置の製造方法
EP0134847B1 (en) 1983-08-02 1987-05-27 Trutek Research Inc. Inhalation valve
US4544933A (en) 1983-09-20 1985-10-01 Siemens Aktiengesellschaft Apparatus and method for ink droplet ejection for a printer
EP0156409A3 (en) 1984-02-23 1986-06-25 Jean Michel Anthony Device for moistening parts of the human body
US4593291A (en) 1984-04-16 1986-06-03 Exxon Research And Engineering Co. Method for operating an ink jet device to obtain high resolution printing
JPS618357A (ja) 1984-06-22 1986-01-16 Toshiba Corp ドツトプリンタ
DE3574344D1 (en) 1984-08-29 1989-12-28 Omron Tateisi Electronics Co Ultrasonic atomizer
US4628890A (en) 1984-08-31 1986-12-16 Freeman Winifer W Fuel atomizer
EP0174033B1 (en) 1984-09-07 1991-03-27 OMRON Corporation Oscillating construction for an ultrasonic atomizing inhaler
US4826759A (en) 1984-10-04 1989-05-02 Bio-Metric Systems, Inc. Field assay for ligands
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4550325A (en) 1984-12-26 1985-10-29 Polaroid Corporation Drop dispensing device
DE3500985A1 (de) 1985-01-14 1986-07-17 Siemens AG, 1000 Berlin und 8000 München Anordnung zur erzeugung von einzeltroepfchen in tintenschreibeinrichtungen
JPS61215059A (ja) 1985-03-22 1986-09-24 Toshiba Corp インクジエツト記録装置
SE447318B (sv) 1985-05-21 1986-11-03 Nils Goran Stemme Integrerad halvledarkrets med fog av termiskt isolerande fogemne, sett att framstella kretsen samt dess anvendning i en flodesmetare
DE3523947A1 (de) 1985-07-04 1987-01-08 Draegerwerk Ag Narkosemittelverdunster mit auswechselbarer verdunsterkammer
DE3524701A1 (de) 1985-07-11 1987-01-15 Bosch Gmbh Robert Ultraschallzerstaeuberduese
US4613326A (en) 1985-07-12 1986-09-23 Becton, Dickinson And Company Two-component medication syringe assembly
US4659014A (en) 1985-09-05 1987-04-21 Delavan Corporation Ultrasonic spray nozzle and method
US4702418A (en) 1985-09-09 1987-10-27 Piezo Electric Products, Inc. Aerosol dispenser
WO1987002895A1 (fr) * 1985-11-08 1987-05-21 Disetronic Ag Instrument d'injection
EP0426205B1 (en) 1985-12-02 1993-07-21 Marco Alfredo Ganser Device for the control of electro-hydraulically actuated fuel injectors
US4753579A (en) 1986-01-22 1988-06-28 Piezo Electric Products, Inc. Ultrasonic resonant device
US4678680A (en) 1986-02-20 1987-07-07 Xerox Corporation Corrosion resistant aperture plate for ink jet printers
JPS62221352A (ja) 1986-03-22 1987-09-29 株式会社新素材総合研究所 酸素による薬液の変質を防止する薬液入りプラスチック容器の製造方法
SE8601351D0 (sv) 1986-03-24 1986-03-24 Nilsson Sven Erik Styrd administration av fysiologiskt aktiva emnen
US4658269A (en) 1986-06-02 1987-04-14 Xerox Corporation Ink jet printer with integral electrohydrodynamic electrodes and nozzle plate
US4849303A (en) 1986-07-01 1989-07-18 E. I. Du Pont De Nemours And Company Alloy coatings for electrical contacts
US4799622A (en) 1986-08-05 1989-01-24 Tao Nenryo Kogyo Kabushiki Kaisha Ultrasonic atomizing apparatus
DE3627222A1 (de) 1986-08-11 1988-02-18 Siemens Ag Ultraschall-taschenzerstaeubergeraet
US4819834A (en) 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
US4871489A (en) 1986-10-07 1989-10-03 Corning Incorporated Spherical particles having narrow size distribution made by ultrasonic vibration
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4979959A (en) 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
DE3636669C2 (de) 1986-10-28 2001-08-16 Siemens Ag Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten
DE3637631C1 (de) 1986-11-05 1987-08-20 Philips Patentverwaltung Verfahren zum Aufbringen kleiner schmelzfluessiger,tropfenfoermiger Lotmengen aus einer Duese auf zu benetzende Flaechen und Vorrichtung zur Durchfuehrung des Verfahrens
US4976259A (en) 1986-12-22 1990-12-11 Mountain Medical Equipment, Inc. Ultrasonic nebulizer
EP0282616B1 (de) 1987-03-17 1989-10-04 Lechler GmbH & Co.KG Ultraschall-Flüssigkeitszerstäuber
JPS63230957A (ja) 1987-03-20 1988-09-27 Hitachi Ltd 液体微粒化装置
US4850534A (en) 1987-05-30 1989-07-25 Tdk Corporation Ultrasonic wave nebulizer
DE3775054D1 (de) 1987-06-16 1992-01-16 Akzo Nv Zweikammer-spritze und herstellungsverfahren.
US5199424A (en) 1987-06-26 1993-04-06 Sullivan Colin E Device for monitoring breathing during sleep and control of CPAP treatment that is patient controlled
US5522382A (en) 1987-06-26 1996-06-04 Rescare Limited Device and method for treating obstructed breathing having a delay/ramp feature
IL86799A (en) 1987-07-02 1993-03-15 Kabi Pharmacia Ab Method and device for injection
US5080093A (en) 1987-07-08 1992-01-14 Vortran Medical Technology, Inc. Intermittant signal actuated nebulizer
US5322057A (en) 1987-07-08 1994-06-21 Vortran Medical Technology, Inc. Intermittent signal actuated nebulizer synchronized to operate in the exhalation phase, and its method of use
US4805609A (en) * 1987-07-17 1989-02-21 Josephine A. Roberts Pressurized ventilation system for patients
US5388571A (en) 1987-07-17 1995-02-14 Roberts; Josephine A. Positive-pressure ventilator system with controlled access for nebulizer component servicing
DE3724629A1 (de) 1987-07-22 1989-02-02 Siemens Ag Piezoelektrisch anregbares resonanzsystem
US5139016A (en) 1987-08-07 1992-08-18 Sorin Biomedica S.P.A. Process and device for aerosol generation for pulmonary ventilation scintigraphy
FI82808C (fi) 1987-12-31 1991-04-25 Etelae Haemeen Keuhkovammayhdi Ultraljudfinfoerdelningsanordning.
DE3808308A1 (de) 1988-03-12 1989-09-21 Merck Patent Gmbh Oeffnungshilfe fuer ampullen
US5115971A (en) 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device
NL8801260A (nl) 1988-05-16 1989-12-18 Mobacc Bv Sproeikop voor een spuitbus.
DE3818682A1 (de) 1988-06-01 1989-12-21 Deussen Stella Kg Ampulle
US5201322A (en) 1988-08-17 1993-04-13 Elf Atochem North America, Inc. Device for detecting air flow through a passageway
US4922901A (en) 1988-09-08 1990-05-08 R. J. Reynolds Tobacco Company Drug delivery articles utilizing electrical energy
DE3916840A1 (de) 1988-09-21 1990-03-29 Bernd Hansen Ampulle
US5511726A (en) 1988-09-23 1996-04-30 Battelle Memorial Institute Nebulizer device
US5021701A (en) 1988-10-20 1991-06-04 Tdk Corporation Piezoelectric vibrator mounting system for a nebulizer
USD312209S (en) 1988-10-21 1990-11-20 Becton, Dickinson And Company Dispensing vial or the like
JP2685847B2 (ja) 1988-11-15 1997-12-03 松下電工株式会社 超音波式噴霧装置
EP0373237A1 (de) 1988-12-13 1990-06-20 Siemens Aktiengesellschaft Inhalationsgerät, insbesondere Taschen-Inhalationsgerät
JP2888437B2 (ja) 1989-01-14 1999-05-10 松下電工株式会社 超音波式噴霧装置
SE466684B (sv) 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
JPH02269058A (ja) 1989-03-14 1990-11-02 Seiko Epson Corp レーリーモード弾性表面波による液滴ジェット装置
JPH03505424A (ja) 1989-04-14 1991-11-28 アゼルバイジャンスキ　ポリテフニチェスキ　インスティテュト　イメニ　チェー．イルドリマ 液状媒質の超音波霧化装置
US5022587A (en) 1989-06-07 1991-06-11 Hochstein Peter A Battery powered nebulizer
US5086785A (en) 1989-08-10 1992-02-11 Abrams/Gentille Entertainment Inc. Angular displacement sensors
US5562608A (en) 1989-08-28 1996-10-08 Biopulmonics, Inc. Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation
US5024733A (en) 1989-08-29 1991-06-18 At&T Bell Laboratories Palladium alloy electroplating process
US5007419A (en) 1989-09-25 1991-04-16 Allan Weinstein Inhaler device
US5227168A (en) 1989-11-21 1993-07-13 Bruce Barber Method of treating a wound
US5152456A (en) 1989-12-12 1992-10-06 Bespak, Plc Dispensing apparatus having a perforate outlet member and a vibrating device
US5002048A (en) 1989-12-12 1991-03-26 Makiej Jr Walter J Inhalation device utilizing two or more aerosol containers
CH680546A5 (https=) 1989-12-15 1992-09-15 Klaus Weigelt Dr Ing
US4971665A (en) 1989-12-18 1990-11-20 Eastman Kodak Company Method of fabricating orifice plates with reusable mandrel
US5016024A (en) 1990-01-09 1991-05-14 Hewlett-Packard Company Integral ink jet print head
US4954225A (en) 1990-01-10 1990-09-04 Dynamics Research Corporation Method for making nozzle plates
DK0440846T3 (da) 1990-02-07 1993-07-12 Vetter & Co Apotheker Dobbeltkammersprøjte og anvendelsesfremgangsmåde
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
US5122116A (en) 1990-04-24 1992-06-16 Science Incorporated Closed drug delivery system
FR2662672B1 (fr) 1990-05-31 1992-08-21 Aerosols & Bouchage Dispensateur de melange.
GB9015077D0 (en) 1990-07-09 1990-08-29 Riker Laboratories Inc Inhaler
US5309135A (en) 1990-07-13 1994-05-03 Langford Gordon B Flexible potentiometer in a horn control system
US5157372A (en) 1990-07-13 1992-10-20 Langford Gordon B Flexible potentiometer
FR2665849B1 (fr) 1990-08-20 1995-03-24 Dynamad Dispositif ultrasonique pour la production en continu de particules.
US5086765A (en) 1990-08-29 1992-02-11 Walter Levine Nebulizer
USD327008S (en) 1990-08-29 1992-06-16 True Products Sampling, Inc. Cosmetic sample container
US5115803A (en) 1990-08-31 1992-05-26 Minnesota Mining And Manufacturing Company Aerosol actuator providing increased respirable fraction
GB9020555D0 (en) 1990-09-20 1990-10-31 Bespak Plc Dispensing apparatus
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
DE69117127T2 (de) 1990-10-11 1996-11-07 Toda Koji Ultraschall-Zerstäuber
CA2027690A1 (en) 1990-10-18 1992-04-19 Christian Laing Plastic ampul
GB9023281D0 (en) 1990-10-25 1990-12-05 Riker Laboratories Inc Inhaler
US5129579A (en) 1990-10-25 1992-07-14 Sun Microsystems, Inc. Vacuum attachment for electronic flux nozzle
NZ241034A (en) 1990-12-17 1995-03-28 Minnesota Mining & Mfg Inhaler device with a dosage control that deactivates an aerosol generator after predetermined time or dosage
US5062419A (en) 1991-01-07 1991-11-05 Rider Donald L Nebulizer with valved "T" assembly
US5147073A (en) 1991-02-11 1992-09-15 Spruhventile Gmbh Fluid pump dispenser for pharmaceutical use
US5217148A (en) 1991-02-11 1993-06-08 Spruhventile Gmbh Pharmaceutical pump dispenser
DE69430303T2 (de) 1991-03-05 2002-11-28 Aradigm Corp Verfahren und vorrichtung zur korrektur eines nullsignals eines drucksensors fur einen durchflussmesser
US5392768A (en) 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5404871A (en) 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5186164A (en) 1991-03-15 1993-02-16 Puthalath Raghuprasad Mist inhaler
WO1992017231A1 (en) 1991-03-28 1992-10-15 Innomed, Inc. Microelectronic inhaler having a counter and timer
US5348189A (en) 1991-04-10 1994-09-20 Bespak Plc Air purge pump dispenser
US5993805A (en) 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
US5938117A (en) 1991-04-24 1999-08-17 Aerogen, Inc. Methods and apparatus for dispensing liquids as an atomized spray
US6540154B1 (en) 1991-04-24 2003-04-01 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US5164740A (en) 1991-04-24 1992-11-17 Yehuda Ivri High frequency printing mechanism
US6629646B1 (en) 1991-04-24 2003-10-07 Aerogen, Inc. Droplet ejector with oscillating tapered aperture
US5160334A (en) * 1991-04-30 1992-11-03 Utah Medical Products, Inc. Electrosurgical generator and suction apparatus
DE69210096T2 (de) 1991-05-27 1996-09-19 Tdk Corp Ultraschallzerstäuber
JPH0614756Y2 (ja) 1991-06-26 1994-04-20 株式会社アルテ 組み立て式の２室式容器兼用注射器
WO1993000951A1 (en) 1991-07-02 1993-01-21 Inhale, Inc. Method and device for delivering aerosolized medicaments
WO1993001404A1 (en) 1991-07-08 1993-01-21 Yehuda Ivri Ultrasonic fluid ejector
DE4124032A1 (de) 1991-07-19 1993-01-21 Bosch Gmbh Robert Messelement
US5180482A (en) 1991-07-22 1993-01-19 At&T Bell Laboratories Thermal annealing of palladium alloys
US5230496A (en) 1991-08-06 1993-07-27 Med-Safe Systems, Inc. Pole mounting clamp
US5601077A (en) 1991-08-07 1997-02-11 Becton, Dickinson And Company Nasal syringe sprayer with removable dose limiting structure
DE4127650C1 (https=) 1991-08-21 1993-02-25 Arzneimittel Gmbh Apotheker Vetter & Co Ravensburg, 7980 Ravensburg, De
CA2116579A1 (en) 1991-08-29 1993-03-18 Christoph Klein Medical device for inhaling doses of spray
US5170782A (en) 1991-09-12 1992-12-15 Devilbiss Health Care, Inc. Medicament nebulizer with improved aerosol chamber
DK0540775T3 (da) 1991-11-07 1997-08-25 Ritzau Pari Werk Gmbh Paul Forstøver især til anvendelse i apparater til inhalationsterapi
DE69206824C5 (de) 1991-12-04 2009-07-09 The Technology Partnership PLC, Melbourn, Royston Vorrichtung und verfahren zur erzeugung von fluessigkeitstroepfchen
EP0546964B1 (en) 1991-12-10 1997-04-09 TDK Corporation An ultrasonic wave nebulizer
AU3664693A (en) 1992-02-13 1993-09-03 Bio-Metric Systems, Inc. Immobilization of chemical species in crosslinked matrices
US5355872B1 (en) 1992-03-04 1998-10-20 John H Riggs Low flow rate nebulizer apparatus and method of nebulization
US5186166A (en) 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
JPH05271980A (ja) 1992-03-30 1993-10-19 Yazaki Corp パラジウム−ニッケル合金メッキ液
WO1993020949A1 (fr) 1992-04-09 1993-10-28 Omron Corporation Atomiseur a ultrasons, inhalateur a ultrasons et procede de commande de ceux-ci
EP0933138B1 (en) 1992-04-09 2004-03-03 Omron Healthcare Co., Ltd. Ultrasonic atomizer
GB9207940D0 (en) 1992-04-10 1992-05-27 Alcan Int Ltd Motors
US5248087A (en) 1992-05-08 1993-09-28 Dressler John L Liquid droplet generator
EP0739654A3 (de) * 1992-05-13 1997-01-02 Siemens Ag Zerstäubungsgerät, insbesondere Taschen-Zerstäubungsgerät
US5512474A (en) 1992-05-29 1996-04-30 Bsi Corporation Cell culture support containing a cell adhesion factor and a positively-charged molecule
US5431155A (en) 1992-06-03 1995-07-11 Elettro Plastica S.P.A. Single-dose nasal dispenser for atomized liquid drugs
JP3178945B2 (ja) 1992-08-25 2001-06-25 日本碍子株式会社 インクジェットプリントヘッド
DE4230645C2 (de) 1992-09-12 1996-03-07 Bernd Hansen Ampulle
US5372126A (en) 1992-09-14 1994-12-13 Blau; Anthony D. Pulmonary sampling chamber
US5392769A (en) 1992-10-06 1995-02-28 Vinatroics Division One-way valve
US5357946A (en) 1992-10-19 1994-10-25 Sherwood Medical Company Ventilator manifold with accessory access port and adaptors therefore
US5445141A (en) 1992-10-19 1995-08-29 Sherwood Medical Company Respiratory support system
EP0595290B1 (en) 1992-10-27 1997-07-30 Canon Kabushiki Kaisha Method for driving liquid
US5313955A (en) 1992-10-30 1994-05-24 Rodder Jerome A Pulmonary flow head
GB2272389B (en) 1992-11-04 1996-07-24 Bespak Plc Dispensing apparatus
US5414075A (en) 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
US5346132A (en) 1992-11-12 1994-09-13 Gary S. Hahn Mist generator
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US5547131A (en) * 1992-12-04 1996-08-20 Bespak Plc Dispensing device with spray nozzle and driven piston
US5452711A (en) 1992-12-24 1995-09-26 Exar Corporation Small form factor atomizer
US5449502A (en) 1992-12-30 1995-09-12 Sanden Corp. Sterilizing apparatus utilizing ultrasonic vibration
US5342011A (en) 1993-01-19 1994-08-30 Sherwood Medical Company Fluid container attachment adaptor for an ambulatory fluid delivery system
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US6012450A (en) 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
DE69426415T2 (de) 1993-01-29 2001-07-26 Aradigm Corp., Hayward Intrapulmonares hormonabgabesystem
US5724957A (en) 1993-01-29 1998-03-10 Aradigm Corporation Intrapulmonary delivery of narcotics
US5350116A (en) 1993-03-01 1994-09-27 Bespak Plc Dispensing apparatus
US5458289A (en) 1993-03-01 1995-10-17 Bespak Plc Liquid dispensing apparatus with reduced clogging
US5279568A (en) 1993-04-30 1994-01-18 Spruhventile Gmbh Pharmaceutical pump dispenser for fluid suspensions and fluid mixtures
US5303854A (en) 1993-03-08 1994-04-19 Spruhventile Gmbh Pharmaceutical pump dispenser having hydraulically closed outlet port
GB9305975D0 (en) 1993-03-23 1993-05-12 Minnesota Mining & Mfg Metered-dose aerosol valves
US5383906A (en) 1993-05-12 1995-01-24 Burchett; Mark T. Nursing bottle with medication dispenser
US5396883A (en) 1993-05-18 1995-03-14 Knupp; Jacob E. Nebulizer valve assembly for use in a ventilation circuit
US5709202A (en) 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US5497763A (en) 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
FR2705911B1 (fr) 1993-06-02 1995-08-11 Oreal Appareil de nébulisation piézoélectrique.
US5819730A (en) 1993-06-09 1998-10-13 Glaxo Wellcome Australia Ltd. Device for administering pharmaceutical substances
GB9312984D0 (en) 1993-06-23 1993-08-04 Bespak Plc Atomising dispenser
JP3553599B2 (ja) 1993-06-29 2004-08-11 インジェット ディジタル エアロソルズ リミテッド ディスペンサー
US5433343A (en) * 1993-07-30 1995-07-18 Meshberg; Philip Delivery system for measured quantities of liquids, especially medications
US5437267A (en) 1993-08-03 1995-08-01 Weinstein; Allan Device for delivering aerosol to the nasal membranes and method of use
CH686872A5 (de) 1993-08-09 1996-07-31 Disetronic Ag Medizinisches Inhalationsgeraet.
US5426458A (en) 1993-08-09 1995-06-20 Hewlett-Packard Corporation Poly-p-xylylene films as an orifice plate coating
US5918637A (en) 1993-08-16 1999-07-06 Fleischman; William H. Plates perforated with venturi-like orifices
US5415161A (en) 1993-09-15 1995-05-16 Ryder; Steven L. Intermittant demand aerosol control device
GB9324250D0 (en) 1993-11-25 1994-01-12 Minnesota Mining & Mfg Inhaler
GB9412669D0 (en) 1994-06-23 1994-08-10 The Technology Partnership Plc Liquid spray apparatus
US5752502A (en) 1993-12-16 1998-05-19 King; Russell Wayne General purpose aerosol inhalation apparatus
US5489266A (en) 1994-01-25 1996-02-06 Becton, Dickinson And Company Syringe assembly and method for lyophilizing and reconstituting injectable medication
US5632878A (en) 1994-02-01 1997-05-27 Fet Engineering, Inc. Method for manufacturing an electroforming mold
US5579757A (en) 1994-02-02 1996-12-03 Baxter International, Inc. Anti-siphon flow restricter for a nebulizer
US5479920A (en) 1994-03-01 1996-01-02 Vortran Medical Technology, Inc. Breath actuated medicinal aerosol delivery apparatus
US5664557A (en) 1994-03-10 1997-09-09 Respiratory Delivery Systems, Inc. Releasably engageable coupling for an inhaler
USD375352S (en) 1994-03-14 1996-11-05 Columbia Laboratories, Inc. Dispensing vial for feminine hygiene products
US5435282A (en) 1994-05-19 1995-07-25 Habley Medical Technology Corporation Nebulizer
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
USD362390S (en) 1994-06-02 1995-09-19 Automatic Liquid Packaging, Inc. Hermetically sealed vial
US5516043A (en) 1994-06-30 1996-05-14 Misonix Inc. Ultrasonic atomizing device
US5666946A (en) 1994-07-13 1997-09-16 Respirogenics Corporation Apparatus for delivering drugs to the lungs
FR2722765B1 (fr) 1994-07-25 1996-08-23 Oreal Recipient permettant le stockage d'au moins deux produits, le melange de ces produits et la distribution du melange ainsi obtenu
GB9418870D0 (en) 1994-09-19 1994-11-09 Minnesota Mining & Mfg Aerosol dispenser comprising contents indicator
US5664706A (en) 1994-10-13 1997-09-09 Bespak Plc Apparatus for dispensing liquid in aerosol spray form
AU128844S (en) 1994-10-21 1996-12-05 Glaxo Wellcome Australia Ltd Ampoule
GB9421687D0 (en) 1994-10-27 1994-12-14 Aid Medic Ltd Dosimetric spacer
US5560837A (en) 1994-11-08 1996-10-01 Hewlett-Packard Company Method of making ink-jet component
US5707818A (en) 1994-12-13 1998-01-13 Bsi Corporation Device and method for simultaneously performing multiple competitive immunoassays
US5582330A (en) 1994-12-28 1996-12-10 Allergan, Inc. Specific volume dispenser
US5588166A (en) 1995-01-04 1996-12-31 Burnett; John Medical attachment device
US5685491A (en) 1995-01-11 1997-11-11 Amtx, Inc. Electroformed multilayer spray director and a process for the preparation thereof
GB2298406B (en) 1995-02-21 1998-05-06 Bespak Plc Dual component dispensing apparatus
NO950760L (no) 1995-02-28 1996-08-29 Elkem Materials Fremgangsmåte for fremstilling av alkylhalosilaner
DE59505300D1 (de) 1995-03-09 1999-04-15 Hansen Bernd Flasche aus Kunststoff und Verfahren zu ihrer Herstellung
DE69605025T2 (de) * 1995-03-14 2000-07-20 Siemens Ag Ultraschallzerstäuber mit abnehmbarer präzisionsdosiereinheit
US5970974A (en) 1995-03-14 1999-10-26 Siemens Aktiengesellschaft Dosating unit for an ultrasonic atomizer device
US5503628A (en) 1995-03-15 1996-04-02 Jettek, Inc. Patient-fillable hypodermic jet injector
US5533497A (en) 1995-03-27 1996-07-09 Ryder; Steven L. Sidestream aerosol generator and method in variable positions
US6427682B1 (en) 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US6014970A (en) 1998-06-11 2000-01-18 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6205999B1 (en) 1995-04-05 2001-03-27 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US20020121274A1 (en) 1995-04-05 2002-09-05 Aerogen, Inc. Laminated electroformed aperture plate
US6782886B2 (en) * 1995-04-05 2004-08-31 Aerogen, Inc. Metering pumps for an aerosolizer
US5474059A (en) 1995-04-08 1995-12-12 Cooper; Guy F. Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
US5657926A (en) 1995-04-13 1997-08-19 Toda; Kohji Ultrasonic atomizing device
US6029666A (en) 1995-05-02 2000-02-29 Alexander Aloy Device for delivering a ventilation gas
JP3318578B2 (ja) 1995-05-26 2002-08-26 サーモディックス，インコーポレイティド 内皮化を促進するための方法及び移植用製品
JP3320261B2 (ja) 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
US5584285A (en) 1995-06-07 1996-12-17 Salter Labs Breathing circuit apparatus for a nebulizer
US5609798A (en) 1995-06-07 1997-03-11 Msp Corporation High output PSL aerosol generator
US5654007A (en) 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5829723A (en) 1995-06-28 1998-11-03 Medex, Inc. Medical device mounting structure
US5904773A (en) 1995-08-11 1999-05-18 Atotech Usa, Inc. Fluid delivery apparatus
US6000396A (en) 1995-08-17 1999-12-14 University Of Florida Hybrid microprocessor controlled ventilator unit
SE9502957D0 (sv) 1995-08-28 1995-08-28 Pharmacia Ab Device for displacing a member in a container
JP3115805B2 (ja) * 1995-09-14 2000-12-11 矢崎総業株式会社 端子金具及び端子金具の製造方法
US5639851A (en) 1995-10-02 1997-06-17 Ethicon, Inc. High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers
JP3317827B2 (ja) 1995-10-09 2002-08-26 株式会社ユニシアジェックス 投薬器
US6254219B1 (en) 1995-10-25 2001-07-03 Hewlett-Packard Company Inkjet printhead orifice plate having related orifices
US6123413A (en) 1995-10-25 2000-09-26 Hewlett-Packard Company Reduced spray inkjet printhead orifice
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
ATE206626T1 (de) * 1995-11-09 2001-10-15 Disetronic Licensing Ag Injektionsvorrichtung
US5807335A (en) 1995-12-22 1998-09-15 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
FR2743313B1 (fr) 1996-01-04 1998-02-06 Imra Europe Sa Dispositif de pulverisation a rendement eleve notamment d'eau sous forme de micro-gouttelettes
US6026809A (en) 1996-01-25 2000-02-22 Microdose Technologies, Inc. Inhalation device
US5694920A (en) * 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US5823179A (en) 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
USD392184S (en) 1996-02-21 1998-03-17 Automatic Liquid Packaging, Inc. Vial with a frangible closure
FR2746656B1 (fr) 1996-03-26 1999-05-28 System Assistance Medical Nebuliseur a capteur de pression
US5790151A (en) 1996-03-27 1998-08-04 Imaging Technology International Corp. Ink jet printhead and method of making
SE9601719D0 (sv) 1996-05-06 1996-05-06 Siemens Elema Ab Doserare för tillförsel av tillsatsgas eller vätska till andningsgas vid anestesiapparat eller ventilator
AUPN976496A0 (en) 1996-05-10 1996-05-30 Glaxo Wellcome Australia Ltd Unit dose dispensing device
US5976344A (en) 1996-05-10 1999-11-02 Lucent Technologies Inc. Composition for electroplating palladium alloys and electroplating process using that composition
US6090080A (en) * 1996-07-05 2000-07-18 Disetronic Licensing Ag Injection device for injection of liquid
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
JP3418507B2 (ja) 1996-08-07 2003-06-23 ワイケイケイ株式会社 圧電振動制御方法
AUPO247496A0 (en) 1996-09-23 1996-10-17 Resmed Limited Assisted ventilation to match patient respiratory need
US5775506A (en) 1996-09-25 1998-07-07 Abbott Laboratories Pharmaceutical ampul
DE19647947A1 (de) 1996-11-20 1998-05-28 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
AUPP855099A0 (en) 1999-02-09 1999-03-04 Resmed Limited Gas delivery connection assembly
US5954268A (en) 1997-03-03 1999-09-21 Joshi; Ashok V. Fluid delivery system
US5948483A (en) 1997-03-25 1999-09-07 The Board Of Trustees Of The University Of Illinois Method and apparatus for producing thin film and nanoparticle deposits
SE509141C2 (sv) 1997-04-10 1998-12-07 Nobel Biocare Ab Arrangemang och system för dental produktframställning och informationsgivning
US6336454B1 (en) 1997-05-16 2002-01-08 Resmed Limited Nasal ventilation as a treatment for stroke
US6055869A (en) 1997-06-12 2000-05-02 Stemme; Erik Lift force fluid flow sensor for measuring fluid flow velocities
US5839617A (en) 1997-07-29 1998-11-24 Owens-Illinois Closure Inc. Pump dispenser
GB2327895B (en) * 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
US6045215A (en) 1997-08-28 2000-04-04 Hewlett-Packard Company High durability ink cartridge printhead and method for making the same
US6145963A (en) 1997-08-29 2000-11-14 Hewlett-Packard Company Reduced size printhead for an inkjet printer
US6139674A (en) 1997-09-10 2000-10-31 Xerox Corporation Method of making an ink jet printhead filter by laser ablation
EP1829618A3 (en) 1997-10-06 2007-09-19 Omron Healthcare Co., Ltd. Atomizer
ATE215820T1 (de) 1997-10-08 2002-04-15 Sepracor Inc Dosierungsform zur verabreichung von aerosolen
US6155676A (en) 1997-10-16 2000-12-05 Hewlett-Packard Company High-durability rhodium-containing ink cartridge printhead and method for making the same
US6037587A (en) 1997-10-17 2000-03-14 Hewlett-Packard Company Chemical ionization source for mass spectrometry
US6039696A (en) 1997-10-31 2000-03-21 Medcare Medical Group, Inc. Method and apparatus for sensing humidity in a patient with an artificial airway
AUPP026997A0 (en) 1997-11-07 1997-12-04 Resmed Limited Administration of cpap treatment pressure in presence of apnea
DK0923957T3 (da) 1997-11-19 2002-02-18 Microflow Eng Sa Dyseemne og væskedråbesprøjteindretning til en inhalator egnet til respirationsterapi
US6096011A (en) 1998-01-29 2000-08-01 Medrad, Inc. Aseptic connector and fluid delivery system using such an aseptic connector
US6358058B1 (en) 1998-01-30 2002-03-19 1263152 Ontario Inc. Aerosol dispensing inhaler training device
US6223746B1 (en) 1998-02-12 2001-05-01 Iep Pharmaceutical Devices Inc. Metered dose inhaler pump
US6158431A (en) 1998-02-13 2000-12-12 Tsi Incorporated Portable systems and methods for delivery of therapeutic material to the pulmonary system
US6204182B1 (en) 1998-03-02 2001-03-20 Hewlett-Packard Company In-situ fluid jet orifice
JP2003504092A (ja) 1998-03-05 2003-02-04 バテル・メモリアル・インスティテュート 肺投薬システムおよび方法
GB9808182D0 (en) 1998-04-17 1998-06-17 The Technology Partnership Plc Liquid projection apparatus
DE19822031C2 (de) * 1998-05-15 2000-03-23 Disetronic Licensing Ag Autoinjektionsgerät
US7731704B2 (en) * 1998-05-19 2010-06-08 Lexion Medical, Llc Method and apparatus for delivering an agent to the abdomen
US6068148A (en) 1998-05-26 2000-05-30 Automatic Liquid Packaging, Inc. Hermetically sealed container including a nozzle with a sealing bead
US20020104530A1 (en) 1998-06-11 2002-08-08 Aerogen, Inc. Piezoelectric polymer flow sensor and methods
US6152130A (en) 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
US6106504A (en) 1998-07-15 2000-08-22 Urrutia; Hector Drip chamber for medical fluid delivery system
US6182662B1 (en) 1998-07-23 2001-02-06 Mcghee Chad J. Intravenous transport/support device
AUPP496198A0 (en) 1998-07-31 1998-08-20 Resmed Limited Switches with graphical display
GB2343122B (en) * 1998-10-26 2003-01-08 Medic Aid Ltd Improvements in and relating to nebulisers
AUPP693398A0 (en) 1998-11-05 1998-12-03 Resmed Limited Fault diagnosis in CPAP and NIPPV devices
ATE344108T1 (de) 1998-12-01 2006-11-15 Microflow Eng Sa Inhalator mit ultraschallzerstäuber dessen sprühöffnungen den maximalamplituden eines stehenden wellenmusters überlagert sind
JP3312216B2 (ja) 1998-12-18 2002-08-05 オムロン株式会社 噴霧装置
US6163588A (en) 1998-12-23 2000-12-19 General Electric Company Core plate and reactor internal pump differential pressure lines for a boiling water reactor
US6116234A (en) 1999-02-01 2000-09-12 Iep Pharmaceutical Devices Inc. Metered dose inhaler agitator
US6196218B1 (en) 1999-02-24 2001-03-06 Ponwell Enterprises Ltd Piezo inhaler
US6328030B1 (en) 1999-03-12 2001-12-11 Daniel E. Kidwell Nebulizer for ventilation system
AUPQ019899A0 (en) 1999-05-06 1999-06-03 Resmed Limited Control of supplied pressure in assisted ventilation
US6328033B1 (en) 1999-06-04 2001-12-11 Zohar Avrahami Powder inhaler
SE9902627D0 (sv) * 1999-07-08 1999-07-08 Siemens Elema Ab Medical nebulizer
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US6216916B1 (en) 1999-09-16 2001-04-17 Joseph S. Kanfer Compact fluid pump
US6530370B1 (en) 1999-09-16 2003-03-11 Instrumentation Corp. Nebulizer apparatus
JP3673893B2 (ja) 1999-10-15 2005-07-20 日本碍子株式会社 液滴吐出装置
DE19962280A1 (de) 1999-12-23 2001-07-12 Draeger Medizintech Gmbh Ultraschallvernebler
US6948491B2 (en) 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7600511B2 (en) 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
MXPA02010884A (es) 2000-05-05 2003-03-27 Aerogen Ireland Ltd Aparato y metodo para el suministro de medicamentos al sistema respiratorio.
US7100600B2 (en) 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US6341732B1 (en) 2000-06-19 2002-01-29 S. C. Johnson & Son, Inc. Method and apparatus for maintaining control of liquid flow in a vibratory atomizing device
US6543443B1 (en) 2000-07-12 2003-04-08 Aerogen, Inc. Methods and devices for nebulizing fluids
US6769626B1 (en) 2000-10-30 2004-08-03 Instrumentarium Corp. Device and method for detecting and controlling liquid supply to an apparatus discharging liquids
US6581595B1 (en) 2000-11-14 2003-06-24 Sensormedics Corporation Positive airway pressure device with indirect calorimetry system
US20020078958A1 (en) 2000-12-21 2002-06-27 Sensormedics Corporation Infant CPAP system with airway pressure control
US6546927B2 (en) 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
US7225807B2 (en) * 2001-03-15 2007-06-05 Creare Incorporated Systems and methods for aerosol delivery of agents
US6550472B2 (en) 2001-03-16 2003-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids using flow directors
US6554201B2 (en) 2001-05-02 2003-04-29 Aerogen, Inc. Insert molded aerosol generator and methods
US20020162551A1 (en) 2001-05-02 2002-11-07 Litherland Craig M. Cymbal-shaped actuator for a nebulizing element
US6732944B2 (en) 2001-05-02 2004-05-11 Aerogen, Inc. Base isolated nebulizing device and methods
US6851626B2 (en) 2002-01-07 2005-02-08 Aerogen, Inc. Methods and devices for nebulizing fluids
EP1471960B1 (en) * 2002-01-07 2019-03-13 Novartis AG Devices for nebulizing fluids for inhalation
US6745770B2 (en) 2002-01-08 2004-06-08 Resmed Limited Flow diverter for controlling the pressure and flow rate in a CPAP device
ES2562682T3 (es) 2002-01-15 2016-03-07 Novartis Ag Sistema para liberar aerosoles del espacio muerto anatómico efectivo
EP1474196B1 (en) 2002-01-15 2016-08-17 Novartis AG Methods and systems for operating an aerosol generator
US6860268B2 (en) 2002-02-06 2005-03-01 Shelly Bohn Pediatric ventilation mask and headgear system
US8245708B2 (en) 2002-05-07 2012-08-21 The Research Foundation Of State University Of New York Methods, devices and formulations for targeted endobronchial therapy
AU2003256253A1 (en) 2002-05-20 2003-12-02 Aerogen, Inc. Aerosol for medical treatment and methods
DE202004021759U1 (de) 2003-02-21 2010-10-07 ResMed Ltd., Bella Vista Nasale Anordnung
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication

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