JP4327909B2 - 組み換え生物による１，３―プロパンジオールの生産方法 - Google Patents

組み換え生物による１，３―プロパンジオールの生産方法 Download PDF

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JP4327909B2
JP4327909B2 JP52268698A JP52268698A JP4327909B2 JP 4327909 B2 JP4327909 B2 JP 4327909B2 JP 52268698 A JP52268698 A JP 52268698A JP 52268698 A JP52268698 A JP 52268698A JP 4327909 B2 JP4327909 B2 JP 4327909B2
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glycerol
seq
sequence
amino acid
gene
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JP2001504338A5 (enExample
JP2001504338A (ja
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ゲイトンビイ，アンソニー・アーサー
ヘイニイ，シヤロン・ロレツタ
ナガラジヤン，バサンサ
ネア，ラメシユ・ブイ
ナカムラ，チヤールズ・イー
ペイン，マーク・スコツト
ピカタジオ，スチーブン・ケネス
デイアズ―トレス，マリア
フス，アミイ・クアング―フア
ラロウ，リチヤード・デイ
トリンバー，ドナルド・イー
ホワイテド，グレゴリー・エム
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イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー
ジエネンカー・インターナシヨナル・インコーポレーテツド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/823—Lower fungi, e.g. mold
    • Y10S530/824—Yeasts

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP52268698A 1996-11-13 1997-11-10 組み換え生物による１，３―プロパンジオールの生産方法 Expired - Fee Related JP4327909B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3060196P 1996-11-13 1996-11-13
US60/030,601 1996-11-13
PCT/US1997/020292 WO1998021339A1 (en) 1996-11-13 1997-11-10 Method for the production of 1,3-propanediol by recombinant organisms

Publications (3)

Publication Number Publication Date
JP2001504338A JP2001504338A (ja) 2001-04-03
JP2001504338A5 JP2001504338A5 (enExample) 2005-06-16
JP4327909B2 true JP4327909B2 (ja) 2009-09-09

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JP52268698A Expired - Fee Related JP4327909B2 (ja) 1996-11-13 1997-11-10 組み換え生物による１，３―プロパンジオールの生産方法
JP52287098A Ceased JP2001503636A (ja) 1996-11-13 1997-11-13 １，３―プロパンジオールの組換え生産方法

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JP52287098A Ceased JP2001503636A (ja) 1996-11-13 1997-11-13 １，３―プロパンジオールの組換え生産方法

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US (3) US6013494A (enExample)
EP (2) EP0942989B1 (enExample)
JP (2) JP4327909B2 (enExample)
KR (1) KR100509310B1 (enExample)
CN (2) CN1236063C (enExample)
AT (2) ATE452979T1 (enExample)
AU (2) AU733534B2 (enExample)
BR (2) BR9712761B1 (enExample)
CA (2) CA2269088C (enExample)
DE (2) DE69739715D1 (enExample)
DK (1) DK0946732T3 (enExample)
ES (1) ES2336858T3 (enExample)
ID (1) ID21487A (enExample)
IL (2) IL129722A0 (enExample)
MY (1) MY131754A (enExample)
NZ (1) NZ335392A (enExample)
WO (2) WO1998021339A1 (enExample)
ZA (1) ZA9710194B (enExample)

Families Citing this family (171)

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Publication number Priority date Publication date Assignee Title
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US6428767B1 (en) * 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
JP4330041B2 (ja) 1996-11-13 2009-09-09 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 組換え生物体によるグリセロールの製造方法
JP4327909B2 (ja) * 1996-11-13 2009-09-09 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組み換え生物による１，３―プロパンジオールの生産方法
BR9815361B1 (pt) 1997-12-02 2010-10-05 método para produção de glicerol a partir de um microorganismo recombinante e microorganismo hospedeiro transformado.
GB9806762D0 (en) * 1998-03-31 1998-05-27 Neutec Pharma Plc Treatment and diagnosis of staphylococcal infections
US7074608B1 (en) 1998-05-12 2006-07-11 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis
US6432686B1 (en) * 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
DE69938105T2 (de) 1998-08-04 2009-01-29 Metabolix, Inc., Cambridge Herstellung von polyhydroxyalkanoaten aus polyolen
US6468773B1 (en) * 1999-05-19 2002-10-22 Genencor International, Inc. Mutant 1,3-propandiol dehydrogenase
FR2796081B1 (fr) 1999-07-09 2003-09-26 Agronomique Inst Nat Rech Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
CA2380616C (en) * 1999-08-18 2011-05-24 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high titer
EP1586647A1 (en) * 1999-08-18 2005-10-19 E.I. du Pont de Nemours and Company Process for the biological production of 1,3-propanediol with high titer
WO2001016346A1 (en) * 1999-08-30 2001-03-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6803218B1 (en) 1999-09-24 2004-10-12 Genencor Intl., Inc. Enzymes which dehydrate glycerol
FR2800751B1 (fr) 1999-11-09 2003-08-29 Roquette Freres Procede de production de 1,3 propanediol par voie fermentaire
FR2801058B1 (fr) 1999-11-16 2002-01-18 Roquette Freres Procede de purification du 1,3-propanediol a partir d'un milieu de fermentation
EP1211234A3 (en) 2000-11-29 2003-11-26 Samsung Electronics Co., Ltd. Process for preparing 1,3-alkandiols from 3-hydroxyesters
US6617478B2 (en) 2000-11-29 2003-09-09 Samsung Electronics Co., Ltd. Process for preparing a 1,3-alkandiol from 3-hydroxyester
DE60327804D1 (de) * 2002-01-18 2009-07-09 Novozymes As Alanin-2,3-aminomutase
CA2481414C (en) 2002-04-22 2013-04-09 E.I. Du Pont De Nemours And Company Promoter and plasmid system for genetic engineering
CN1653174A (zh) * 2002-05-08 2005-08-10 巴斯福植物科学有限公司 用于提高植物含油量的方法
WO2004016760A2 (en) 2002-08-16 2004-02-26 Genencor International, Inc. Novel variant hyprocrea jecorina cbh1 cellulases
AU2003287028B2 (en) 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
EP2428573A3 (en) 2002-10-04 2012-06-27 Genecor International, Inc. Improved production of bacterial strains cross reference to related applications
AU2003287625A1 (en) 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
EP1583818A4 (en) 2002-12-16 2007-08-15 Du Pont B12 DEPENDENT DEHYDRATASES WITH IMPROVED REACTION KINETICS
US20050233030A1 (en) * 2004-03-10 2005-10-20 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
MXPA05009553A (es) * 2003-03-10 2006-03-17 Broin And Associates Inc Metodo para producir etanol utilizando almidon como materia prima.
US7767788B2 (en) * 2003-03-21 2010-08-03 The Research Foundation Of State University Of New York Folding protein functioning as a molecular switch
EP2385104A1 (en) 2003-04-01 2011-11-09 Danisco US Inc. Variant Scytalidium thermophilium CBH1
US7056439B2 (en) * 2003-05-06 2006-06-06 Tate & Lyle Ingredidents Americas, Inc. Process for producing 1, 3-propanediol
DE602004028359D1 (de) 2003-05-06 2010-09-09 Du Pont Reinigung von biologisch produziertem 1,3-propandiol
ATE550424T1 (de) 2003-11-21 2012-04-15 Danisco Us Inc Expression granuläre stärke hydrolysierender enzyme in trichoderma und verfahren zur herstellung von glucose aus granulären stärkesubstraten
US20050239181A1 (en) * 2004-03-10 2005-10-27 Broin And Associates, Inc. Continuous process for producing ethanol using raw starch
EP1731604A4 (en) * 2004-03-26 2007-04-04 Nippon Catalytic Chem Ind PROCESS FOR THE PREPARATION OF 1,3-PROPANEL AND / OR 3-HYDROXYPROPIONIC ACID
WO2006022664A2 (en) * 2004-07-30 2006-03-02 Cargill Incorporated Alanine 2, 3 aminomutases
US8008056B2 (en) 2004-12-30 2011-08-30 Danisco Us Inc. Variant Hypocrea jecorina CBH2 cellulases
US7781191B2 (en) * 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
JP5149785B2 (ja) * 2005-04-12 2013-02-20 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー エタノールを得るためのバイオマスの処理
US20070029252A1 (en) * 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
US20070037267A1 (en) * 2005-05-02 2007-02-15 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
CN1327001C (zh) * 2005-06-03 2007-07-18 清华大学 利用生物柴油副产物甘油生产1,3－丙二醇的方法
WO2006138437A2 (en) * 2005-06-16 2006-12-28 Wabash Technologies, Inc. Pedal assembly having a hysteresis mechanism
CN100427605C (zh) * 2005-06-17 2008-10-22 清华大学 一种由粗淀粉原料生产1,3-丙二醇和2,3-丁二醇的方法
US7919289B2 (en) 2005-10-10 2011-04-05 Poet Research, Inc. Methods and systems for producing ethanol using raw starch and selecting plant material
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
NZ566406A (en) 2005-10-26 2012-04-27 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
CN100392071C (zh) * 2005-12-05 2008-06-04 中国农业大学 产乳酸途径缺失的工程菌及其构建方法与应用
CN100463968C (zh) * 2006-01-27 2009-02-25 华侨大学 一种由生物催化转化甘油制备1,3-丙二醇和二羟基丙酮的方法
CN101379184B (zh) * 2006-02-06 2011-12-14 帝斯曼知识产权资产管理有限公司 新颖的氧化还原酶及其用途
US20070275139A1 (en) * 2006-02-10 2007-11-29 Melissa Joerger Food compositions comprising renewably-based, biodegradable1,3-propanediol
US20070213247A1 (en) 2006-02-10 2007-09-13 Gyorgyi Fenyvesi Detergent and liquid soap compositions comprising biologically-based mono and di esters
CN1935991B (zh) * 2006-06-21 2010-05-12 南宁中诺生物工程有限责任公司 产气荚膜梭菌甘油脱水酶基因及其1,3-丙二醇的生产方法
JP5130811B2 (ja) * 2006-07-19 2013-01-30 東レ株式会社 連続発酵による１，３−プロパンジオールの製造方法
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
JP2010508013A (ja) * 2006-10-31 2010-03-18 メタボリック エクスプローラー グリセロールから１，３−プロパンジオールを高収量で生物学的に製造する方法
US20080176957A1 (en) * 2006-11-15 2008-07-24 Dupont Tate & Lyle Bio Products Company, Llc Preservative compositions comprising renewably-based, biodegradable 1,3-propanediol
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
CN101130782B (zh) * 2007-07-23 2011-01-26 江南大学 以葡萄糖为底物产1,3-丙二醇重组酿酒酵母的构建方法
US8445236B2 (en) * 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
US7819976B2 (en) * 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
US20090053800A1 (en) * 2007-08-22 2009-02-26 Julie Friend Biomass Treatment Apparatus
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
DE102007041862A1 (de) 2007-09-03 2009-03-19 Evonik Degussa Gmbh Mikrobiologische Herstellung von Isoprenoiden
CN101939435A (zh) 2007-09-21 2011-01-05 巴斯夫植物科学有限公司 具有增加的产量的植物
CN101205541B (zh) * 2007-10-18 2010-12-08 北京化工大学 重组表达载体和用其转化的宿主细胞发酵甘油高产1,3-丙二醇的方法
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
CN101918539A (zh) 2007-12-17 2010-12-15 阿姆斯特丹大学 包含发酵基因卡盒的自养生物进行光驱动的co2还原生成有机化合物以用作燃料或用作工业半成品
DE102007060705A1 (de) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-Aminocarbonsäuren oder ihre Lactame, herstellende, rekombinante Zellen
CN102057041B (zh) 2008-06-06 2014-10-15 丹尼斯科美国公司 包含具有与非纤维素物质降低的亲和力的纤维素酶变体的组合物和方法
DE102008002715A1 (de) 2008-06-27 2009-12-31 Evonik Röhm Gmbh 2-Hydroxyisobuttersäure produzierende rekombinante Zelle
DE102008041299A1 (de) 2008-08-18 2010-02-25 Evonik Degussa Gmbh Neuartiges, universell einsetzbares addiction-System
EP2326709A4 (en) * 2008-09-15 2013-01-23 Opx Biotechnologies Inc METHODS, SYSTEMS AND COMPOSITIONS RELATED TO REDUCED MICROBIAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP) IN ALDEHYDMETABOLITE
WO2010066411A2 (en) 2008-12-10 2010-06-17 Direvo Industrial Biotechnology Gmbh Polypeptides having cellobiohydrolase ii activity
US20100159521A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Ozone treatment of biomass to enhance enzymatic saccharification
US9068206B1 (en) 2009-03-03 2015-06-30 Poet Research, Inc. System for treatment of biomass to facilitate the production of ethanol
EP2403954B1 (en) 2009-03-03 2015-04-22 POET Research, Inc. Method for fermentation of biomass for the production of ethanol
US8450094B1 (en) 2009-03-03 2013-05-28 Poet Research, Inc. System for management of yeast to facilitate the production of ethanol
US20100233771A1 (en) * 2009-03-03 2010-09-16 Mcdonald William F System for pre-treatment of biomass for the production of ethanol
CN102803482B (zh) 2009-06-03 2015-04-29 丹尼斯科美国公司 具有改善的表达、活性和/或稳定性的纤维素酶变体，及其用途
WO2011038364A1 (en) 2009-09-27 2011-03-31 Opx Biotechnologies, Inc. Method for producing 3-hydroxypropionic acid and other products
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
DE102009046623A1 (de) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase
DE102010014680A1 (de) 2009-11-18 2011-08-18 Evonik Degussa GmbH, 45128 Zellen, Nukleinsäuren, Enzyme und deren Verwendung sowie Verfahren zur Herstellung von Sophorolipiden
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
US20110136190A1 (en) * 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
US8034592B2 (en) 2009-12-10 2011-10-11 The Curators Of The University Of Missouri Fossil fuel-free process of lignocellulosic pretreatment with biological hydrogen production
RU2012132908A (ru) 2010-02-11 2014-03-20 Метаболикс, Инк. Способ получения производных химических соединений
KR101144235B1 (ko) * 2010-02-25 2012-05-10 한국과학기술연구원 바이오에탄올 폐발효액을 이용한 부탄올의 제조방법
US9303274B2 (en) * 2010-04-19 2016-04-05 Sapporo Breweries Limited Microorganism, and hydrogen production process, 1,3-propanediol production process and biodiesel liquid waste treatment method each using the microorganism
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
KR101220499B1 (ko) * 2010-05-25 2013-01-10 한국생명공학연구원 글리세롤로부터 3-하이드록시프로피온산을 고수율로 제조하는 방법
EP4242320A3 (en) 2010-07-12 2023-11-29 Inbiose N.V. Metabolically engineered organisms for the production of added value bio-products
DE102010032484A1 (de) 2010-07-28 2012-02-02 Evonik Goldschmidt Gmbh Zellen und Verfahren zur Herstellung von Rhamnolipiden
US20120040414A1 (en) * 2010-09-01 2012-02-16 Eric Knight Expression of Steady State Metabolic Pathways
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
CN103649321B (zh) * 2011-04-05 2019-07-16 拉勒曼德匈牙利流动性管理有限责任公司 用于通过添加交替电子受体改善微生物中的产品收率和产量的方法
US9242930B2 (en) 2011-04-13 2016-01-26 Elc Management Llc Mild anionic surfactants suitable for personal care compositions
CA2830978C (en) 2011-04-13 2016-01-05 Elc Management Llc Conditioning agents for personal care compositions
FR2976949B1 (fr) * 2011-06-21 2015-08-28 Sanofi Sa Procede de preparation de levures genetiquement transformees capables de produire une molecule d'interet a haut titre
US8969598B2 (en) 2011-06-24 2015-03-03 Eastman Chemical Company Production of cyclic acetals or ketals using liquid-phase acid catalysts
US9056313B2 (en) 2011-06-24 2015-06-16 Eastman Chemical Company Catalysts for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US9388105B2 (en) 2011-06-24 2016-07-12 Eastman Chemical Company Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals
US8829206B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals or ketals using solid acid catalysts
US8785697B2 (en) 2011-06-24 2014-07-22 Eastman Chemical Company Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8829207B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals by reactive distillation
US9000229B2 (en) 2011-06-24 2015-04-07 Eastman Chemical Company Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
EP2540834A1 (en) 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
JP2013013353A (ja) * 2011-07-01 2013-01-24 Daicel Corp １，３−プロパンジオールの製造方法
JP2013070675A (ja) * 2011-09-28 2013-04-22 Daicel Corp アルキルジオールを産生する組換え菌の培養方法
DE102012201360A1 (de) 2012-01-31 2013-08-01 Evonik Industries Ag Zellen und Verfahren zur Herstellung von Rhamnolipiden
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
CN102634543A (zh) * 2012-05-04 2012-08-15 杭玉玲 微生物发酵生产1,3-丙二醇的方法
BR112014030203B1 (pt) 2012-06-08 2021-10-13 Cj Cheiljedang Corporation Processo para produção de produtos de ácido acrílico de base biológica
BR112015002940A2 (pt) 2012-08-10 2018-04-24 Opx Biotechnologies Inc microorganismos e métodos para a produção de ácidos graxos e produtos derivados de ácidos graxos.
KR101437040B1 (ko) * 2012-08-17 2014-09-02 삼성전자 주식회사 삼투압 보호제 첨가에 의한 1,3-프로판디올 생산방법 및 생산용 배지
WO2014036152A1 (en) * 2012-08-28 2014-03-06 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
KR20150093190A (ko) 2012-12-12 2015-08-17 다니스코 유에스 인크. 셀로바이오하이드롤라제의 변이체
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
WO2014127053A2 (en) 2013-02-13 2014-08-21 Metabolix, Inc. Process for ultra pure chemical production from biobased raw starting materials
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
WO2014160262A1 (en) 2013-03-14 2014-10-02 Abengoa Bioenergy New Technologies, Llc Methods for converting cellulosic waste to bioproducts
US10584860B2 (en) * 2013-03-14 2020-03-10 Ideal Industries, Llc Linear light fixture with interchangeable light engine unit
WO2014160050A1 (en) * 2013-03-14 2014-10-02 Butamax Advanced Biofuels Llc Glycerol 3- phosphate dehydrogenase for butanol production
EP2976141A4 (en) 2013-03-15 2016-10-05 Cargill Inc FLASHING FOR PRODUCTION CLEANING AND RECOVERY
US9447438B2 (en) 2013-03-15 2016-09-20 Cargill, Incorporated Acetyl-coA carboxylases
WO2015010103A2 (en) 2013-07-19 2015-01-22 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
KR102266181B1 (ko) 2013-09-03 2021-06-17 피티티 글로벌 케미컬 퍼블릭 컴퍼니 리미티드 1,3-프로판디올로부터 아크릴산, 아크릴로니트릴 및 1,4-부탄디올의 제조방법
CN105531373A (zh) * 2013-09-06 2016-04-27 密苏里州立大学校董 盐碱条件下甘油向1,3-丙二醇的转化
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
KR101532736B1 (ko) * 2014-02-24 2015-07-09 한국생명공학연구원 2,3-부탄디올 합성 유전자가 결실된 미생물 변이체를 이용한 1,3-프로판디올의 제조방법
FR3015186A1 (fr) * 2014-03-11 2015-06-26 Antoine Piccirilli Utilisation d'une composition renfermant du 1,3-propanediol comme e-liquide
EP2949214A1 (en) 2014-05-26 2015-12-02 Evonik Degussa GmbH Methods of producing rhamnolipids
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
EP3056561A1 (de) 2015-02-16 2016-08-17 Evonik Degussa GmbH Mikroorganismen mit reduzierter Enzymaktivität
WO2016131801A1 (en) 2015-02-19 2016-08-25 Evonik Degussa Gmbh Rhamnolipid synthesis
EP3288012B1 (en) * 2015-04-20 2022-04-27 Pi-Crystal Incorporation Method for manufacturing active matrix array device, and active matrix array device manufactured thereby
CN104774879B (zh) * 2015-04-29 2017-10-20 大连理工大学 一种混菌发酵甘油生产1,3‑丙二醇的方法
US20180230446A1 (en) 2015-07-29 2018-08-16 Abengoa Bioenergía Nuevas Tecnologías, S.A. Expression of recombinant beta-xylosidase enzymes
US9968531B2 (en) 2015-08-05 2018-05-15 Dupont Tate & Lyle Bio Products Company, Llc Deodorants containing 1,3-propanediol
EP3192866A1 (en) 2016-01-15 2017-07-19 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Endocellulases and uses thereof
CN109415716A (zh) 2016-04-08 2019-03-01 纳幕尔杜邦公司 用于酵母的阿拉伯糖异构酶
JP7597507B2 (ja) 2016-10-24 2024-12-10 エボニック オペレーションズ ゲーエムベーハー 代替グルコーストランスポーターを使用してラムノリピドを製造するための細胞および方法
US11685905B2 (en) 2016-10-24 2023-06-27 Evonik Operations Gmbh Rhamnolipid-producing cell having reduced glucose dehydrogenase activity
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
EP3502126A1 (en) 2017-12-19 2019-06-26 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Ancestral cellulases and uses thereof
KR102103408B1 (ko) * 2018-01-16 2020-04-23 한국과학기술원 1,3-프로판디올 생성능을 가지는 변이미생물 및 이를 이용한 1,3-pdo의 제조방법
US20190233853A1 (en) * 2018-02-01 2019-08-01 Invista North America S.A.R.L. Methods and materials for the biosynthesis of beta hydroxy acids and/or derivatives thereof and/or compounds related thereto
JP7411557B2 (ja) 2018-02-09 2024-01-11 エボニック オペレーションズ ゲーエムベーハー グルコリピドを含有する混合組成物
US11390889B2 (en) 2018-10-30 2022-07-19 Green Earth Institute Co., Ltd. Method for manufacturing 1,3-propanediol
CN109370969B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在制备1，3-丙二醇中的应用
CN109337852B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在生产1,3-丙二醇中的应用
CN109750011B (zh) * 2019-02-20 2022-05-10 中国科学院天津工业生物技术研究所 一种甘露糖6-磷酸磷酸酶及甘露糖生物制备方法
KR20210128742A (ko) * 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
CN116323929A (zh) * 2020-11-05 2023-06-23 株式会社Lg化学 具有从葡萄糖生产3-羟基丙酸能力的微生物及其用途
CN112625994B (zh) * 2021-01-05 2022-04-15 清华大学 一种重组需钠弧菌及其应用
CN114806981B (zh) * 2021-01-18 2023-05-23 中国科学院上海高等研究院 克雷伯氏菌工程菌在生产1,3-丙二醇中的应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用
WO2024231217A1 (en) 2023-05-11 2024-11-14 Evonik Operations Gmbh Glucolipid production

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3634764A1 (de) 1986-10-11 1988-04-14 Mueller Haidmann Roland Dipl I Aus platten zusammengesetzte decke
DE3734764A1 (de) * 1987-10-14 1989-05-03 Huels Chemische Werke Ag Verfahren zur herstellung von propandiol-(1,3)
EP0373230B1 (en) * 1988-12-12 1993-02-17 Unilever N.V. Process for the microbiological preparation of 1,3-propane-diol from glycerol
US5633362A (en) * 1995-05-12 1997-05-27 E. I. Du Pont De Nemours And Company Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
US5686276A (en) * 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5599689A (en) * 1995-05-12 1997-02-04 E. I. Du Pont De Nemours And Company Process for making 1,3-propanediol from carbohydrates using mixed microbial cultures
JP4327909B2 (ja) * 1996-11-13 2009-09-09 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組み換え生物による１，３―プロパンジオールの生産方法

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