KR100509310B1 - 재조합 유기체에 의한 1,3-프로판디올의 생산 방법 - Google Patents

재조합 유기체에 의한 1,3-프로판디올의 생산 방법 Download PDF

Info

Publication number
KR100509310B1
KR100509310B1 KR10-1999-7004181A KR19997004181A KR100509310B1 KR 100509310 B1 KR100509310 B1 KR 100509310B1 KR 19997004181 A KR19997004181 A KR 19997004181A KR 100509310 B1 KR100509310 B1 KR 100509310B1
Authority
KR
South Korea
Prior art keywords
ala
leu
seq
val
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR10-1999-7004181A
Other languages
English (en)
Korean (ko)
Other versions
KR20000053213A (ko
Inventor
안토니 아더 게이튼비
샤론 로레타 헤이니
바산싸 나가라잔
라메쉬 브이. 네어
챨스 이. 나까무라
마크 스코트 패인
스티븐 케네쓰 피카타지오
마리아 다이아스-토레스
아미 쿠앙-후아 슈
리챠드 디. 라로
도날드 이. 트림버
그레고리 엠. 화이티드
Original Assignee
이 아이 듀폰 디 네모아 앤드 캄파니
제넨코 인터내셔날 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이 아이 듀폰 디 네모아 앤드 캄파니, 제넨코 인터내셔날 인코포레이티드 filed Critical 이 아이 듀폰 디 네모아 앤드 캄파니
Publication of KR20000053213A publication Critical patent/KR20000053213A/ko
Application granted granted Critical
Publication of KR100509310B1 publication Critical patent/KR100509310B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/823—Lower fungi, e.g. mold
    • Y10S530/824—Yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
KR10-1999-7004181A 1996-11-13 1997-11-10 재조합 유기체에 의한 1,3-프로판디올의 생산 방법 Expired - Fee Related KR100509310B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3060196P 1996-11-13 1996-11-13
US60/030,601 1996-11-13

Publications (2)

Publication Number Publication Date
KR20000053213A KR20000053213A (ko) 2000-08-25
KR100509310B1 true KR100509310B1 (ko) 2005-08-22

Family

ID=21854996

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-1999-7004181A Expired - Fee Related KR100509310B1 (ko) 1996-11-13 1997-11-10 재조합 유기체에 의한 1,3-프로판디올의 생산 방법

Country Status (18)

Country Link
US (3) US6013494A (enExample)
EP (2) EP0942989B1 (enExample)
JP (2) JP4327909B2 (enExample)
KR (1) KR100509310B1 (enExample)
CN (2) CN1236063C (enExample)
AT (2) ATE452979T1 (enExample)
AU (2) AU733534B2 (enExample)
BR (2) BR9712761B1 (enExample)
CA (2) CA2269088C (enExample)
DE (2) DE69739715D1 (enExample)
DK (1) DK0946732T3 (enExample)
ES (1) ES2336858T3 (enExample)
ID (1) ID21487A (enExample)
IL (2) IL129722A0 (enExample)
MY (1) MY131754A (enExample)
NZ (1) NZ335392A (enExample)
WO (2) WO1998021339A1 (enExample)
ZA (1) ZA9710194B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015126112A1 (ko) * 2014-02-24 2015-08-27 한국생명공학연구원 2,3-부탄디올 합성 유전자가 결실된 미생물 변이체를 이용한 1,3-프로판디올의 제조방법

Families Citing this family (170)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US6428767B1 (en) 1995-05-12 2002-08-06 E. I. Du Pont De Nemours And Company Method for identifying the source of carbon in 1,3-propanediol
EP0948628B1 (en) * 1996-11-13 2010-06-23 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
ATE452979T1 (de) * 1996-11-13 2010-01-15 Du Pont Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen
AU1619199A (en) 1997-12-02 1999-06-16 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
GB9806762D0 (en) * 1998-03-31 1998-05-27 Neutec Pharma Plc Treatment and diagnosis of staphylococcal infections
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US7074608B1 (en) 1998-05-12 2006-07-11 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for coenzyme B12 synthesis
JP5042407B2 (ja) 1998-08-04 2012-10-03 メタボリックス，インコーポレイテッド ポリオールからのポリヒドロキシアルカノエートの産生
US6468773B1 (en) * 1999-05-19 2002-10-22 Genencor International, Inc. Mutant 1,3-propandiol dehydrogenase
FR2796081B1 (fr) 1999-07-09 2003-09-26 Agronomique Inst Nat Rech Procede de preparation du 1,3-propanediol par un micro-organisme recombinant en l'absence de coenzyme b12 ou de l'un de ses precurseurs
DK1204755T3 (da) 1999-08-18 2006-12-11 Du Pont Proces til biologisk produktion af 1,3-propandiol
EP1586647A1 (en) * 1999-08-18 2005-10-19 E.I. du Pont de Nemours and Company Process for the biological production of 1,3-propanediol with high titer
DE60030403D1 (de) * 1999-08-30 2006-10-12 Wisconsin Alumni Res Found Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
US6803218B1 (en) * 1999-09-24 2004-10-12 Genencor Intl., Inc. Enzymes which dehydrate glycerol
FR2800751B1 (fr) 1999-11-09 2003-08-29 Roquette Freres Procede de production de 1,3 propanediol par voie fermentaire
FR2801058B1 (fr) 1999-11-16 2002-01-18 Roquette Freres Procede de purification du 1,3-propanediol a partir d'un milieu de fermentation
EP1211234A3 (en) 2000-11-29 2003-11-26 Samsung Electronics Co., Ltd. Process for preparing 1,3-alkandiols from 3-hydroxyesters
US6617478B2 (en) 2000-11-29 2003-09-09 Samsung Electronics Co., Ltd. Process for preparing a 1,3-alkandiol from 3-hydroxyester
EP1575881B1 (en) * 2002-01-18 2009-05-27 Novozymes A/S Alanine 2,3- aminomutase
CN100366730C (zh) 2002-04-22 2008-02-06 纳幕尔杜邦公司 用于遗传工程的启动子和质粒系统
WO2003095655A2 (de) * 2002-05-08 2003-11-20 Basf Plant Science Gmbh Verfahren zum erhöhen des ölgehaltes in pflanzen
CA2865180A1 (en) 2002-08-16 2004-02-26 Genencor International, Inc. Novel variant hyprocrea jecorina cbh1 cellulases
ATE493490T1 (de) 2002-10-04 2011-01-15 Du Pont Verfahren zur biologischen herstellung von 1,3- propandiol mit hoher ausbeute
EP1546304B1 (en) 2002-10-04 2013-05-08 Danisco US Inc. Improved production of bacterial strains
AU2003287625A1 (en) 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
MXPA05006541A (es) 2002-12-16 2005-09-30 Du Pont Deshidratasas dependientes de b12 con cinetica de reaccion mejorada.
CA2517920C (en) * 2003-03-10 2012-12-18 Broin And Associates, Inc. Method for producing ethanol using raw starch
US20050233030A1 (en) 2004-03-10 2005-10-20 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
US7767788B2 (en) * 2003-03-21 2010-08-03 The Research Foundation Of State University Of New York Folding protein functioning as a molecular switch
SI1627050T1 (sl) 2003-04-01 2014-01-31 Danisco Us Inc. Varianta humicola grisea cbh1.1
US7056439B2 (en) * 2003-05-06 2006-06-06 Tate & Lyle Ingredidents Americas, Inc. Process for producing 1, 3-propanediol
EP1625224B1 (en) * 2003-05-06 2010-07-28 E.I. Du Pont De Nemours And Company Purification of biologically-produced 1,3-propanediol
US7303899B2 (en) 2003-11-21 2007-12-04 Genencor International, Inc. Expression of granular starch hydrolyzing enzymes in Trichoderma and process for producing glucose from granular starch substrates
US20050239181A1 (en) * 2004-03-10 2005-10-27 Broin And Associates, Inc. Continuous process for producing ethanol using raw starch
US20070148749A1 (en) * 2004-03-26 2007-06-28 Shinzo Yasuda Process for producting 1,3-propanediol and or/3-hydroxypropionic acid
EP2292750A3 (en) * 2004-07-30 2011-12-21 Novozymes A/S Alanine 2, 3 aminomutases
EP2302049B1 (en) 2004-12-30 2017-01-25 Danisco US Inc. Variant hypocrea jecorina cbh2 cellulases
US20070029252A1 (en) * 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
US7781191B2 (en) * 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
BRPI0612944B1 (pt) * 2005-04-12 2017-11-28 E.I.Du Pont De Nemours And Company Method of production of target substance
WO2006119386A2 (en) * 2005-05-02 2006-11-09 Broin And Associates, Inc. Methods and systems for producing ethanol using raw starch and fractionation
US7524660B2 (en) 2005-05-05 2009-04-28 E.I. Du Pont De Nemours And Company Utilization of fructose in microbial production strains
CN1327001C (zh) * 2005-06-03 2007-07-18 清华大学 利用生物柴油副产物甘油生产1,3－丙二醇的方法
BRPI0611855A2 (pt) * 2005-06-16 2010-10-05 Wabash Technologies Inc conjunto de pedal com um mecanismo de histerese
CN100427605C (zh) * 2005-06-17 2008-10-22 清华大学 一种由粗淀粉原料生产1,3-丙二醇和2,3-丁二醇的方法
DE102005048818A1 (de) 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
US7919289B2 (en) * 2005-10-10 2011-04-05 Poet Research, Inc. Methods and systems for producing ethanol using raw starch and selecting plant material
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
UA96928C2 (ru) 2005-10-26 2011-12-26 Э.И. Дю Пон Де Немур Энд Компани Ферментативное продуцирование спиртов с четырьмя атомами углерода
CN100392071C (zh) * 2005-12-05 2008-06-04 中国农业大学 产乳酸途径缺失的工程菌及其构建方法与应用
CN100463968C (zh) * 2006-01-27 2009-02-25 华侨大学 一种由生物催化转化甘油制备1,3-丙二醇和二羟基丙酮的方法
US20100074991A1 (en) * 2006-02-06 2010-03-25 Mutsaers Johanna Henrica Gerdi Novel oxidoreductases and uses thereof
CN105078773A (zh) * 2006-02-10 2015-11-25 杜邦塔特和莱尔生物产品有限责任公司 包括可再生基生物降解型1,3-丙二醇的生物降解型组合物
US20070275139A1 (en) * 2006-02-10 2007-11-29 Melissa Joerger Food compositions comprising renewably-based, biodegradable1,3-propanediol
CN1935991B (zh) * 2006-06-21 2010-05-12 南宁中诺生物工程有限责任公司 产气荚膜梭菌甘油脱水酶基因及其1,3-丙二醇的生产方法
JP5130811B2 (ja) * 2006-07-19 2013-01-30 東レ株式会社 連続発酵による１，３−プロパンジオールの製造方法
DE102006039203B4 (de) 2006-08-22 2014-06-18 Evonik Degussa Gmbh Verfahren zur Herstellung von durch Kristallisation gereinigter Acrylsäure aus Hydroxypropionsäure sowie Vorrichtung dazu
JP2010508013A (ja) * 2006-10-31 2010-03-18 メタボリック エクスプローラー グリセロールから１，３−プロパンジオールを高収量で生物学的に製造する方法
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
WO2008061187A1 (en) * 2006-11-15 2008-05-22 Dupont Tate & Lyle Bio Products Company, Llc Preservative compositions comprising renewably-based, biodegradable 1,3-propanediol
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
CN101130782B (zh) * 2007-07-23 2011-01-26 江南大学 以葡萄糖为底物产1,3-丙二醇重组酿酒酵母的构建方法
US20090053800A1 (en) * 2007-08-22 2009-02-26 Julie Friend Biomass Treatment Apparatus
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
US7819976B2 (en) * 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
US8445236B2 (en) * 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
DE102007041862A1 (de) 2007-09-03 2009-03-19 Evonik Degussa Gmbh Mikrobiologische Herstellung von Isoprenoiden
US8809059B2 (en) 2007-09-21 2014-08-19 Basf Plant Science Gmbh Plants with increased yield
CN101205541B (zh) * 2007-10-18 2010-12-08 北京化工大学 重组表达载体和用其转化的宿主细胞发酵甘油高产1,3-丙二醇的方法
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
DE102007060705A1 (de) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-Aminocarbonsäuren oder ihre Lactame, herstellende, rekombinante Zellen
CN101918539A (zh) * 2007-12-17 2010-12-15 阿姆斯特丹大学 包含发酵基因卡盒的自养生物进行光驱动的co2还原生成有机化合物以用作燃料或用作工业半成品
EP2628796A1 (en) 2008-06-06 2013-08-21 Danisco US Inc. Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials
DE102008002715A1 (de) 2008-06-27 2009-12-31 Evonik Röhm Gmbh 2-Hydroxyisobuttersäure produzierende rekombinante Zelle
DE102008041299A1 (de) 2008-08-18 2010-02-25 Evonik Degussa Gmbh Neuartiges, universell einsetzbares addiction-System
WO2010031083A2 (en) * 2008-09-15 2010-03-18 Opx Biotechnologies, Inc. Methods, systems and compositions related to reduction of conversions of microbially produced 3-hydroxypropionic acid (3-hp) to aldehyde metabolites
WO2010066411A2 (en) 2008-12-10 2010-06-17 Direvo Industrial Biotechnology Gmbh Polypeptides having cellobiohydrolase ii activity
US20100159521A1 (en) * 2008-12-19 2010-06-24 E. I. Du Pont De Nemours And Company Ozone treatment of biomass to enhance enzymatic saccharification
EP2403954B1 (en) 2009-03-03 2015-04-22 POET Research, Inc. Method for fermentation of biomass for the production of ethanol
US20100233771A1 (en) * 2009-03-03 2010-09-16 Mcdonald William F System for pre-treatment of biomass for the production of ethanol
US9068206B1 (en) 2009-03-03 2015-06-30 Poet Research, Inc. System for treatment of biomass to facilitate the production of ethanol
US8450094B1 (en) 2009-03-03 2013-05-28 Poet Research, Inc. System for management of yeast to facilitate the production of ethanol
US8679816B2 (en) 2009-06-03 2014-03-25 Danisco Us Inc. Cellulase variants with improved expression, activity and stability, and use thereof
MX2012003604A (es) 2009-09-27 2012-09-12 Opx Biotechnologies Inc Metodo para producir acido 3-hidroxipropionico y otros productos.
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
US8852903B2 (en) 2009-10-23 2014-10-07 E I Du Pont De Nemours And Company Co-metabolism of fructose and glucose in microbial production strains
DE102009046623A1 (de) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Verwendung eines zu einem MeaB-Protein homologen Proteins zur Erhöhung der enzymatischen Aktivität einer 3-Hydroxycarbonsäure-CoA-Mutase
DE102010014680A1 (de) 2009-11-18 2011-08-18 Evonik Degussa GmbH, 45128 Zellen, Nukleinsäuren, Enzyme und deren Verwendung sowie Verfahren zur Herstellung von Sophorolipiden
US20110125118A1 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an Organic Acid and/or Related Chemicals
US20110136190A1 (en) * 2009-12-04 2011-06-09 E. I. Du Pont De Nemours And Company Recombinant bacteria for producing glycerol and glycerol-derived products from sucrose
US8034592B2 (en) * 2009-12-10 2011-10-11 The Curators Of The University Of Missouri Fossil fuel-free process of lignocellulosic pretreatment with biological hydrogen production
CN102781901B (zh) 2010-02-11 2016-08-03 梅塔玻利克斯公司 用于从经遗传修饰的聚羟基链烷酸酯生物质制备单体组分的方法
KR101144235B1 (ko) * 2010-02-25 2012-05-10 한국과학기술연구원 바이오에탄올 폐발효액을 이용한 부탄올의 제조방법
JP5667174B2 (ja) * 2010-04-19 2015-02-12 サッポロビール株式会社 新規微生物並びにそれを用いた水素製造方法、１，３−プロパンジオール製造方法及びバイオディーゼル廃液の処理方法
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
KR101220499B1 (ko) * 2010-05-25 2013-01-10 한국생명공학연구원 글리세롤로부터 3-하이드록시프로피온산을 고수율로 제조하는 방법
MX386398B (es) 2010-07-12 2025-03-18 Inbiose Nv Organismos metabólicamente diseñados para la producción de bioproductos de valor agregado.
DE102010032484A1 (de) 2010-07-28 2012-02-02 Evonik Goldschmidt Gmbh Zellen und Verfahren zur Herstellung von Rhamnolipiden
US20120040414A1 (en) * 2010-09-01 2012-02-16 Eric Knight Expression of Steady State Metabolic Pathways
US8129170B1 (en) 2010-12-06 2012-03-06 E.I. Du Pont De Nemours And Company Recombinant bacteria having the ability to metabolize sucrose
CN103649321B (zh) * 2011-04-05 2019-07-16 拉勒曼德匈牙利流动性管理有限责任公司 用于通过添加交替电子受体改善微生物中的产品收率和产量的方法
CN104941507B (zh) 2011-04-13 2017-06-16 Elc管理公司 适用于个人护理组合物的温和型阴离子表面活性剂
CA2830978C (en) 2011-04-13 2016-01-05 Elc Management Llc Conditioning agents for personal care compositions
FR2976949B1 (fr) * 2011-06-21 2015-08-28 Sanofi Sa Procede de preparation de levures genetiquement transformees capables de produire une molecule d'interet a haut titre
US9388105B2 (en) 2011-06-24 2016-07-12 Eastman Chemical Company Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals
US9056313B2 (en) 2011-06-24 2015-06-16 Eastman Chemical Company Catalysts for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8829206B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals or ketals using solid acid catalysts
US8785697B2 (en) 2011-06-24 2014-07-22 Eastman Chemical Company Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8969598B2 (en) 2011-06-24 2015-03-03 Eastman Chemical Company Production of cyclic acetals or ketals using liquid-phase acid catalysts
US9000229B2 (en) 2011-06-24 2015-04-07 Eastman Chemical Company Production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals
US8829207B2 (en) 2011-06-24 2014-09-09 Eastman Chemical Company Production of cyclic acetals by reactive distillation
EP2540834A1 (en) 2011-06-29 2013-01-02 Metabolic Explorer Method for the preparation of 1,3-propanediol
JP2013013353A (ja) * 2011-07-01 2013-01-24 Daicel Corp １，３−プロパンジオールの製造方法
JP2013070675A (ja) * 2011-09-28 2013-04-22 Daicel Corp アルキルジオールを産生する組換え菌の培養方法
DE102012201360A1 (de) 2012-01-31 2013-08-01 Evonik Industries Ag Zellen und Verfahren zur Herstellung von Rhamnolipiden
US9017961B2 (en) 2012-03-05 2015-04-28 E.I. Du Pont De Nemours And Company Recombinant bacteria comprising novel sucrose transporters
US8686114B2 (en) 2012-03-05 2014-04-01 E I Du Pont De Nemours And Company Variant sucrose transporter polypeptides
CN102634543A (zh) * 2012-05-04 2012-08-15 杭玉玲 微生物发酵生产1,3-丙二醇的方法
CN104350034B (zh) 2012-06-08 2018-07-31 Cj 第一制糖株式会社 可再生丙烯酸生产和自其制备的产物
CA2881666A1 (en) 2012-08-10 2014-02-13 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
KR101437040B1 (ko) * 2012-08-17 2014-09-02 삼성전자 주식회사 삼투압 보호제 첨가에 의한 1,3-프로판디올 생산방법 및 생산용 배지
KR102121888B1 (ko) * 2012-08-28 2020-06-12 란자테크 뉴질랜드 리미티드 재조합 미생물 및 이에 대한 용도
MX2015007234A (es) 2012-12-12 2015-10-29 Danisco Us Inc Variantes de celobiohidrolasas.
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
WO2014127053A2 (en) 2013-02-13 2014-08-21 Metabolix, Inc. Process for ultra pure chemical production from biobased raw starting materials
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US10584860B2 (en) * 2013-03-14 2020-03-10 Ideal Industries, Llc Linear light fixture with interchangeable light engine unit
US20140315258A1 (en) 2013-03-14 2014-10-23 Abengoa Bioenergy New Technologies, Llc Methods for converting cellulosic waste to bioproducts
US9441250B2 (en) * 2013-03-14 2016-09-13 Butamax Advanced Biofuels Llc Glycerol 3- phosphate dehydrogenase for butanol production
US9447438B2 (en) 2013-03-15 2016-09-20 Cargill, Incorporated Acetyl-coA carboxylases
CA2905602A1 (en) 2013-03-15 2014-09-18 Sarah M. Hoyt Flash evaporation for product purification and recovery
BR112016001026A2 (pt) 2013-07-19 2017-10-24 Cargill Inc organismo geneticamente modificado
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US10035749B2 (en) 2013-09-03 2018-07-31 Myriant Corporation Process for manufacturing acrylic acid, acrylonitrile and 1,4-butanediol from 1,3-propanediol
WO2015035266A1 (en) * 2013-09-06 2015-03-12 The Curators Of The University Of Missouri Conversion of glycerol to 1,3-propanediol under haloalkaline conditions
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
FR3015186A1 (fr) * 2014-03-11 2015-06-26 Antoine Piccirilli Utilisation d'une composition renfermant du 1,3-propanediol comme e-liquide
EP2949214A1 (en) 2014-05-26 2015-12-02 Evonik Degussa GmbH Methods of producing rhamnolipids
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
EP3056561A1 (de) 2015-02-16 2016-08-17 Evonik Degussa GmbH Mikroorganismen mit reduzierter Enzymaktivität
WO2016131801A1 (en) 2015-02-19 2016-08-25 Evonik Degussa Gmbh Rhamnolipid synthesis
HK1246493A1 (zh) * 2015-04-20 2018-09-07 Pi-克瑞斯托株式会社 有源矩阵阵列装置的制造方法和通过该方法制造的有源矩阵阵列装置
CN104774879B (zh) * 2015-04-29 2017-10-20 大连理工大学 一种混菌发酵甘油生产1,3‑丙二醇的方法
BR112018001855A2 (pt) 2015-07-29 2018-09-25 Abengoa Bioenergia Nuevas Tecnologias Sa expressão de enzimas beta-xilosidase recombinantes
US9968531B2 (en) 2015-08-05 2018-05-15 Dupont Tate & Lyle Bio Products Company, Llc Deodorants containing 1,3-propanediol
EP3192866A1 (en) 2016-01-15 2017-07-19 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Endocellulases and uses thereof
US20190112590A1 (en) 2016-04-08 2019-04-18 Ei Du Pont De Nemours And Company Arabinose isomerases for yeast
CN109843909B (zh) 2016-10-24 2022-07-12 赢创运营有限公司 利用替代的葡萄糖转运蛋白产生鼠李糖脂的细胞和方法
EP3529259A1 (en) 2016-10-24 2019-08-28 Evonik Degussa GmbH Rhamnolipid-producing cell having reduced glucose dehydrogenase activity
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives
EP3502126A1 (en) 2017-12-19 2019-06-26 CIC nanoGUNE - Asociación Centro de Investigación Cooperativa en Nanociencias Ancestral cellulases and uses thereof
KR102103408B1 (ko) * 2018-01-16 2020-04-23 한국과학기술원 1,3-프로판디올 생성능을 가지는 변이미생물 및 이를 이용한 1,3-pdo의 제조방법
US20190233853A1 (en) * 2018-02-01 2019-08-01 Invista North America S.A.R.L. Methods and materials for the biosynthesis of beta hydroxy acids and/or derivatives thereof and/or compounds related thereto
KR20240170982A (ko) 2018-02-09 2024-12-05 에보닉 오퍼레이션스 게엠베하 글루코리피드를 포함하는 혼합 조성물
CN111386345B (zh) * 2018-10-30 2023-05-16 绿色地球研究所株式会社 1,3-丙二醇的制造方法
CN109370969B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在制备1，3-丙二醇中的应用
CN109337852B (zh) * 2018-11-12 2020-09-04 江南大学 一种重组克雷伯氏杆菌在生产1,3-丙二醇中的应用
CN109750011B (zh) * 2019-02-20 2022-05-10 中国科学院天津工业生物技术研究所 一种甘露糖6-磷酸磷酸酶及甘露糖生物制备方法
KR20210128742A (ko) * 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
EP4242312A4 (en) * 2020-11-05 2024-04-24 Lg Chem, Ltd. MICROORGANISMS HAVING THE CAPACITY TO PRODUCE 3-HYDROXYPROPIONIC ACID FROM GLUCOSE AND THEIR USES
CN112625994B (zh) * 2021-01-05 2022-04-15 清华大学 一种重组需钠弧菌及其应用
CN114806981B (zh) * 2021-01-18 2023-05-23 中国科学院上海高等研究院 克雷伯氏菌工程菌在生产1,3-丙二醇中的应用
CN114107145B (zh) * 2021-11-04 2024-05-07 清华大学 一种重组微生物及其在生产1,3-丙二醇中的应用
WO2024231217A1 (en) 2023-05-11 2024-11-14 Evonik Operations Gmbh Glucolipid production

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3634764A1 (de) 1986-10-11 1988-04-14 Mueller Haidmann Roland Dipl I Aus platten zusammengesetzte decke
DE3734764A1 (de) * 1987-10-14 1989-05-03 Huels Chemische Werke Ag Verfahren zur herstellung von propandiol-(1,3)
EP0373230B1 (en) * 1988-12-12 1993-02-17 Unilever N.V. Process for the microbiological preparation of 1,3-propane-diol from glycerol
US5633362A (en) * 1995-05-12 1997-05-27 E. I. Du Pont De Nemours And Company Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
US5686276A (en) * 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
US5599689A (en) * 1995-05-12 1997-02-04 E. I. Du Pont De Nemours And Company Process for making 1,3-propanediol from carbohydrates using mixed microbial cultures
ATE452979T1 (de) * 1996-11-13 2010-01-15 Du Pont Herstellungsverfahren von 1,3-propandiol durch rekombinante organismen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015126112A1 (ko) * 2014-02-24 2015-08-27 한국생명공학연구원 2,3-부탄디올 합성 유전자가 결실된 미생물 변이체를 이용한 1,3-프로판디올의 제조방법

Also Published As

Publication number Publication date
CN1198935C (zh) 2005-04-27
BR9712761A (pt) 1999-10-26
NZ335392A (en) 2000-10-27
AU5248498A (en) 1998-06-03
EP0946732B1 (en) 2006-06-07
BR9712761B1 (pt) 2010-02-23
BR9714313B1 (pt) 2014-10-21
EP0942989B1 (en) 2009-12-23
ID21487A (id) 1999-06-17
ATE452979T1 (de) 2010-01-15
US6953684B2 (en) 2005-10-11
JP2001504338A (ja) 2001-04-03
US6013494A (en) 2000-01-11
CA2269088C (en) 2009-07-28
CN1236063C (zh) 2006-01-11
EP0942989A1 (en) 1999-09-22
US20030022323A1 (en) 2003-01-30
DE69736070T2 (de) 2006-12-21
WO1998021341A2 (en) 1998-05-22
ZA9710194B (en) 1999-05-12
IL129722A (en) 2008-07-08
DK0946732T3 (da) 2006-10-09
MY131754A (en) 2007-08-30
ATE329034T1 (de) 2006-06-15
WO1998021341A3 (en) 1998-06-25
CA2270906A1 (en) 1998-05-22
DE69736070D1 (de) 2006-07-20
CA2269088A1 (en) 1998-05-22
JP2001503636A (ja) 2001-03-21
KR20000053213A (ko) 2000-08-25
CN1244217A (zh) 2000-02-09
JP4327909B2 (ja) 2009-09-09
DE69739715D1 (de) 2010-02-04
WO1998021339A1 (en) 1998-05-22
AU733534B2 (en) 2001-05-17
ES2336858T3 (es) 2010-04-16
AU5507698A (en) 1998-06-03
AU735080B2 (en) 2001-06-28
BR9714313A (pt) 2001-09-18
EP0946732A2 (en) 1999-10-06
CN1239511A (zh) 1999-12-22
US6136576A (en) 2000-10-24
IL129722A0 (en) 2000-02-29

Similar Documents

Publication Publication Date Title
KR100509310B1 (ko) 재조합 유기체에 의한 1,3-프로판디올의 생산 방법
IL129723A (en) Method for the production of glycerol by recombinant microorganisms
KR100525325B1 (ko) 단일미생물에 의한 발효가능한 탄소원의 1,3-프로판디올로의 생물전환
KR100590635B1 (ko) 비타민 ｂ12 수송을 위한 유전자를 포함하는 재조합유기체에 의한 1,3-프로판디올의 제조 방법
US6428767B1 (en) Method for identifying the source of carbon in 1,3-propanediol
US6514733B1 (en) Process for the biological production of 1,3-propanediol with high titer
KR100550203B1 (ko) 재조합 유기체에 의한 글리세롤의 생산방법
MXPA99004405A (en) Method for the production of 1,3-propanediol by recombinant organisms
AU780783B2 (en) Method for the production of glycerol by recombinant organisms
MXPA99004337A (en) Method for the recombinant production of 1,3-propanediol
AU2005203028B2 (en) Method for the production of glycerol by recombinant organisms
AU7156500A (en) Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
MXPA00010723A (en) Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin b12 transport
MXPA02001712A (en) Process for the biological production of 1,3-propanediol with high titer
MXPA99004406A (en) Method for the production of glycerol by recombinant organisms
AU2007249075A1 (en) Bioconversion of fermentable carbon to 1,3-propanediol in a single micro-organism using dehydratases

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

FPAY Annual fee payment

Payment date: 20120719

Year of fee payment: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

FPAY Annual fee payment

Payment date: 20130722

Year of fee payment: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

FPAY Annual fee payment

Payment date: 20140722

Year of fee payment: 10

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

FPAY Annual fee payment

Payment date: 20150716

Year of fee payment: 11

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 11

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20160812

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20160812

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301