JP4317138B2 - 慢性閉塞性肺疾患を治療するための新規医薬 - Google Patents

慢性閉塞性肺疾患を治療するための新規医薬 Download PDF

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Publication number
JP4317138B2
JP4317138B2 JP2004552561A JP2004552561A JP4317138B2 JP 4317138 B2 JP4317138 B2 JP 4317138B2 JP 2004552561 A JP2004552561 A JP 2004552561A JP 2004552561 A JP2004552561 A JP 2004552561A JP 4317138 B2 JP4317138 B2 JP 4317138B2
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hydroxy
ethyl
dimethyl
phenyl
benzo
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JP2006508140A5 (enExample
JP2006508140A (ja
Inventor
ティエリー ブーイスー
フランク ブートネル
インゴ コネツキー
ザビーヌ ペシュテル
アンドレアス シュナップ
ヘルマン ショーレンベルガー
クルト シュロム
クラウディア ハイネ
クラウス ルドルフ
フィリップ ルシュテンベルガー
クリシュトフ ヘンケ
Original Assignee
ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト
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Application filed by ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト filed Critical ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004552561A 2002-11-15 2003-11-11 慢性閉塞性肺疾患を治療するための新規医薬 Expired - Lifetime JP4317138B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (de) 2002-11-15 2002-11-15 Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
PCT/EP2003/012565 WO2004045618A2 (de) 2002-11-15 2003-11-11 Neue arzneimittel zur behandlung von chronisch obstruktiver lungenerkrankung

Publications (3)

Publication Number Publication Date
JP2006508140A JP2006508140A (ja) 2006-03-09
JP2006508140A5 JP2006508140A5 (enExample) 2008-10-09
JP4317138B2 true JP4317138B2 (ja) 2009-08-19

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JP2004552561A Expired - Lifetime JP4317138B2 (ja) 2002-11-15 2003-11-11 慢性閉塞性肺疾患を治療するための新規医薬

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EP (2) EP2025338A1 (enExample)
JP (1) JP4317138B2 (enExample)
KR (1) KR101092247B1 (enExample)
CN (3) CN101735166A (enExample)
AR (2) AR041969A1 (enExample)
AT (1) ATE430569T1 (enExample)
AU (1) AU2003285326B2 (enExample)
BE (1) BE2014C016I2 (enExample)
BR (1) BRPI0316264B8 (enExample)
CA (1) CA2506082C (enExample)
CO (1) CO5570670A2 (enExample)
CY (2) CY1110500T1 (enExample)
DE (2) DE10253282A1 (enExample)
DK (1) DK1562603T3 (enExample)
EA (1) EA008665B1 (enExample)
EC (1) ECSP055774A (enExample)
ES (1) ES2326878T7 (enExample)
FR (1) FR14C0049I2 (enExample)
HR (1) HRP20050432B1 (enExample)
HU (1) HUS1400011I1 (enExample)
IL (1) IL167900A (enExample)
LT (1) LTC1562603I2 (enExample)
LU (1) LU92433I2 (enExample)
ME (1) ME00354B (enExample)
MX (1) MXPA05005081A (enExample)
MY (1) MY136034A (enExample)
NL (1) NL300650I2 (enExample)
NO (2) NO334314B1 (enExample)
NZ (1) NZ540661A (enExample)
PE (1) PE20040694A1 (enExample)
PL (1) PL212238B1 (enExample)
PT (1) PT1562603E (enExample)
RS (1) RS51607B (enExample)
SI (1) SI1562603T1 (enExample)
TW (1) TWI343812B (enExample)
UA (1) UA81276C2 (enExample)
WO (1) WO2004045618A2 (enExample)
ZA (1) ZA200502246B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2007537196A (ja) * 2004-05-14 2007-12-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の鏡像異性的に純粋なベータ−作用薬、その製造方法および製剤の形体におけるその使用

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JP2007537196A (ja) * 2004-05-14 2007-12-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の鏡像異性的に純粋なベータ−作用薬、その製造方法および製剤の形体におけるその使用

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