PT1562603E - Novos medicamentos para o tratamento de doenças pulmonares obstrutivas crónicas - Google Patents

Novos medicamentos para o tratamento de doenças pulmonares obstrutivas crónicas Download PDF

Info

Publication number
PT1562603E
PT1562603E PT03778312T PT03778312T PT1562603E PT 1562603 E PT1562603 E PT 1562603E PT 03778312 T PT03778312 T PT 03778312T PT 03778312 T PT03778312 T PT 03778312T PT 1562603 E PT1562603 E PT 1562603E
Authority
PT
Portugal
Prior art keywords
treatment
chronic obstructive
obstructive pulmonary
pulmonary diseases
novel medicaments
Prior art date
Application number
PT03778312T
Other languages
English (en)
Portuguese (pt)
Inventor
Christoph Hoenke
Klaus Rudolf
Ingo Konetzki
Thierry Bouyssou
Frank Buettner
Sabine Pestel
Andreas Schnapp
Hermann Schollenberger
Kurt Schromm
Claudia Heine
Philipp Lustenberger
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32185709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1562603(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of PT1562603E publication Critical patent/PT1562603E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT03778312T 2002-11-15 2003-11-11 Novos medicamentos para o tratamento de doenças pulmonares obstrutivas crónicas PT1562603E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (de) 2002-11-15 2002-11-15 Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung

Publications (1)

Publication Number Publication Date
PT1562603E true PT1562603E (pt) 2009-06-18

Family

ID=32185709

Family Applications (1)

Application Number Title Priority Date Filing Date
PT03778312T PT1562603E (pt) 2002-11-15 2003-11-11 Novos medicamentos para o tratamento de doenças pulmonares obstrutivas crónicas

Country Status (38)

Country Link
EP (2) EP1562603B3 (enExample)
JP (1) JP4317138B2 (enExample)
KR (1) KR101092247B1 (enExample)
CN (3) CN101735166A (enExample)
AR (2) AR041969A1 (enExample)
AT (1) ATE430569T1 (enExample)
AU (1) AU2003285326B2 (enExample)
BE (1) BE2014C016I2 (enExample)
BR (1) BRPI0316264B8 (enExample)
CA (1) CA2506082C (enExample)
CO (1) CO5570670A2 (enExample)
CY (2) CY1110500T1 (enExample)
DE (2) DE10253282A1 (enExample)
DK (1) DK1562603T3 (enExample)
EA (1) EA008665B1 (enExample)
EC (1) ECSP055774A (enExample)
ES (1) ES2326878T7 (enExample)
FR (1) FR14C0049I2 (enExample)
HR (1) HRP20050432B1 (enExample)
HU (1) HUS1400011I1 (enExample)
IL (1) IL167900A (enExample)
LT (1) LTC1562603I2 (enExample)
LU (1) LU92433I2 (enExample)
ME (1) ME00354B (enExample)
MX (1) MXPA05005081A (enExample)
MY (1) MY136034A (enExample)
NL (1) NL300650I2 (enExample)
NO (2) NO334314B1 (enExample)
NZ (1) NZ540661A (enExample)
PE (1) PE20040694A1 (enExample)
PL (1) PL212238B1 (enExample)
PT (1) PT1562603E (enExample)
RS (1) RS51607B (enExample)
SI (1) SI1562603T1 (enExample)
TW (1) TWI343812B (enExample)
UA (1) UA81276C2 (enExample)
WO (1) WO2004045618A2 (enExample)
ZA (1) ZA200502246B (enExample)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
DE102004019539A1 (de) * 2004-04-22 2005-11-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
DK1781298T3 (da) 2004-04-22 2012-05-07 Boehringer Ingelheim Int Lægemiddelkombinationer indeholdende benzoxazin til behandling af luftvejs-sygdomme
WO2005110990A1 (de) * 2004-05-13 2005-11-24 Boehringer Ingelheim International Gmbh Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
DE102004024453A1 (de) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen
DE102004024451A1 (de) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
DE102004024452A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation von Betaagonisten
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
DE102005007654A1 (de) * 2005-02-19 2006-08-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
US7994211B2 (en) 2005-08-08 2011-08-09 Argenta Discovery Limited Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses
MX2008001976A (es) * 2005-08-15 2008-03-25 Boehringer Ingelheim Int Procedimiento para la preparacion de betamimeticos.
US20070086957A1 (en) * 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
TWI389692B (zh) 2005-10-10 2013-03-21 Boehringer Ingelheim Int 用以吸入β-共效劑的氣溶膠調配物
JP5006330B2 (ja) 2005-10-21 2012-08-22 ノバルティス アーゲー Ｉｌ１３に対するヒト抗体および治療的使用
AU2006311060A1 (en) * 2005-11-09 2007-05-18 Boehringer Ingelheim International Gmbh Aerosolformulation for inhalation
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
JP2009526817A (ja) * 2006-02-16 2009-07-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療用医薬組成物
PE20080142A1 (es) 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion
WO2007121920A2 (en) 2006-04-21 2007-11-01 Novartis Ag Purine derivatives for use as adenosin a2a receptor agonists
JP2010500319A (ja) * 2006-08-07 2010-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 鏡像体上純粋な新規ベータアゴニスト、それらの製造方法及び医薬としてのそれらの使用
UY30542A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de agonistas beta
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
KR20090073121A (ko) 2006-09-29 2009-07-02 노파르티스 아게 Ｐｉ3ｋ 지질 키나제 억제제로서의 피라졸로피리미딘
CA2667962A1 (en) 2006-10-30 2008-05-08 Novartis Ag Heterocyclic compounds as antiinflammatory agents
DK2104535T3 (da) 2007-01-10 2011-04-04 Irm Llc Forbindelser og sammensætninger som kanalaktiverende proteaseinhibitorer
PL2125759T3 (pl) * 2007-01-25 2011-12-30 Boehringer Ingelheim Int Sposób wytwarzania związków betamimetycznych
CN101687851B (zh) 2007-05-07 2013-02-27 诺瓦提斯公司 有机化合物
EA017919B1 (ru) 2007-12-10 2013-04-30 Новартис Аг Производные пиразин-2-карбоксамида для лечения заболеваний, которые поддаются лечению путем блокирования эпителиальных натриевых каналов
CN101910153B (zh) 2008-01-11 2014-01-22 诺华股份有限公司 作为激酶抑制剂的嘧啶类
EA201001848A1 (ru) 2008-06-10 2011-08-30 Новартис Аг Производные пиразина в качестве блокаторов эпителиальных натриевых каналов
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
SI2379507T1 (sl) 2008-12-30 2014-02-28 Pulmagen Therapeutics (Inflammation) Limited Spojine sulfonamida za zdravljenje respiratornih motenj
JP2012516345A (ja) 2009-01-29 2012-07-19 ノバルティス アーゲー 星細胞腫治療用置換ベンゾイミダゾール
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
EA201200260A1 (ru) 2009-08-12 2012-09-28 Новартис Аг Гетероциклические гидразоны и их применение для лечения рака и воспаления
UA111579C2 (uk) 2009-08-17 2016-05-25 Інтеллікіне Ллк ГЕТЕРОЦИКЛІЧНІ ПОХІДНІ 2-АМІНОБЕНЗО[d]ОКСАЗОЛУ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ НА ЇХ ОСНОВІ ТА ЇХ ЗАСТОСУВАННЯ ДЛЯ ЛІКУВАННЯ ЗАХВОРЮВАННЯ, ПОВ'АНОГО З РІ3-КІНАЗОЮ
JP2013508414A (ja) 2009-10-22 2013-03-07 バーテックス ファーマシューティカルズ インコーポレイテッド 嚢胞性線維症および他の慢性疾患の治療のための組成物
GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
GB0918924D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
WO2012040082A2 (en) * 2010-09-21 2012-03-29 Intekrin Therapeutics, Inc. Antidiabetic solid pharmaceutical compositions
US20130324526A1 (en) 2011-02-10 2013-12-05 Novartis Ag [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
EP2678016B1 (en) 2011-02-23 2016-08-10 Intellikine, LLC Heterocyclic compounds and uses thereof
SG192795A1 (en) 2011-02-25 2013-09-30 Irm Llc Compounds and compositions as trk inhibitors
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
AU2012310168B2 (en) 2011-09-15 2015-07-16 Novartis Ag 6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
CN103946221B (zh) 2011-09-16 2016-08-03 诺华股份有限公司 用于治疗囊性纤维化的杂环化合物
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
US9056867B2 (en) 2011-09-16 2015-06-16 Novartis Ag N-substituted heterocyclyl carboxamides
US9174994B2 (en) 2011-11-23 2015-11-03 Intellikine, Llc Enhanced treatment regimens using mTor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
KR102115047B1 (ko) 2012-04-03 2020-05-26 노파르티스 아게 티로신 키나제 억제제들을 갖는 조합 제품 및 그의 용도
WO2014056840A1 (en) 2012-10-09 2014-04-17 Boehringer Ingelheim International Gmbh Beta-2-adrenoceptor agonist for the treatment of cough
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
CN105246482A (zh) 2013-03-15 2016-01-13 因特利凯有限责任公司 激酶抑制剂的组合及其用途
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
BR112016024533A8 (pt) 2014-04-24 2021-03-30 Novartis Ag derivados de amino pirazina como inibidores de fosfatidilinositol 3-cinase ou sal, seu uso, e composição e combinação farmacêuticas
WO2015162461A1 (en) 2014-04-24 2015-10-29 Novartis Ag Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
KR20160145780A (ko) 2014-04-24 2016-12-20 노파르티스 아게 포스파티딜이노시톨 3-키나제 억제제로서의 아미노 피리딘 유도체
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
WO2016016822A1 (en) 2014-07-31 2016-02-04 Novartis Ag Combination therapy
US20200069679A1 (en) 2016-12-12 2020-03-05 Boehringer Ingelheim International Gmbh Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with oladaterol
JP7116060B2 (ja) 2016-12-20 2022-08-09 インケ、ソシエダ、アノニマ Ｒ－６－ヒドロキシ－８－［１－ヒドロキシ－２－［２－（４－メトキシフェニル）－１，１－ジメチルエチルアミノエチル］－２ｈ－１，４－ベンゾオキサジン－３（４ｈ）－オン塩酸塩の改良された製造法
CN109096218B (zh) * 2018-08-06 2020-10-27 上海方予健康医药科技有限公司 盐酸奥达特罗晶型a及其制备方法
CN108997248B (zh) * 2018-08-06 2023-08-01 上海方予健康医药科技有限公司 盐酸奥达特罗晶型b及其制备方法
BR112021024668A2 (pt) 2019-06-10 2022-05-31 Novartis Ag Derivado de piridina e pirazina para o tratamento de fc, dpoc e bronquiectasia
KR20220052934A (ko) 2019-08-28 2022-04-28 노파르티스 아게 치환 1,3-페닐 헤테로아릴 유도체 및 질환 치료에서의 이의 용도
US11304897B2 (en) 2020-06-09 2022-04-19 Anovent Pharmaceutical (U.S.), Llc Pharmaceutical formulation containing umeclidinium bromide and vilanterol trifenatate
US11331322B1 (en) 2021-09-15 2022-05-17 Santen Pharmaceutical Co., Ltd. Medicament for preventing and/or treating dry eye

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134590A1 (de) * 1981-09-01 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue benzo-heterocyclen
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
DE3743265A1 (de) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg Neue ammoniumverbindungen, ihre herstellung und verwendung
SK15382002A3 (sk) * 2000-04-27 2003-03-04 Boehringer Ingelheim Pharma Kg Betamimetiká, farmaceutický prostriedok s ich obsahom a ich použitie

Also Published As

Publication number Publication date
HRP20050432A2 (en) 2006-06-30
NO2014005I1 (no) 2014-03-10
EP1562603B1 (de) 2009-05-06
FR14C0049I2 (fr) 2015-07-24
PL212238B1 (pl) 2012-08-31
CA2506082C (en) 2011-06-21
JP2006508140A (ja) 2006-03-09
AR041969A1 (es) 2005-06-01
FR14C0049I1 (enExample) 2014-08-08
BR0316264A (pt) 2005-10-11
ME00354B (me) 2011-10-10
EP1562603A2 (de) 2005-08-17
DE50311502D1 (de) 2009-06-18
PL375270A1 (en) 2005-11-28
EA200500715A1 (ru) 2005-12-29
MY136034A (en) 2008-07-31
NO334314B1 (no) 2014-02-03
AU2003285326B2 (en) 2009-06-04
RS20050361A (sr) 2007-04-10
ATE430569T1 (de) 2009-05-15
PE20040694A1 (es) 2004-11-23
BRPI0316264B8 (pt) 2021-05-25
ECSP055774A (es) 2005-11-22
ES2326878T3 (es) 2009-10-21
TWI343812B (en) 2011-06-21
BRPI0316264B1 (pt) 2019-04-09
CY2014032I2 (el) 2015-12-09
CN1713914A (zh) 2005-12-28
TW200423943A (en) 2004-11-16
CO5570670A2 (es) 2005-10-31
JP4317138B2 (ja) 2009-08-19
LTC1562603I2 (lt) 2016-12-12
EP1562603B3 (de) 2014-01-08
IL167900A (en) 2013-06-27
ES2326878T7 (es) 2014-03-11
CA2506082A1 (en) 2004-06-03
ZA200502246B (en) 2006-01-25
MEP53608A (en) 2011-05-10
EP2025338A1 (de) 2009-02-18
KR20050075013A (ko) 2005-07-19
SI1562603T1 (sl) 2009-10-31
CN101735166A (zh) 2010-06-16
CN101817800A (zh) 2010-09-01
DE10253282A1 (de) 2004-05-27
NO20052883L (no) 2005-06-14
BE2014C016I2 (enExample) 2023-03-07
WO2004045618A2 (de) 2004-06-03
EA008665B1 (ru) 2007-06-29
DK1562603T3 (da) 2009-09-07
CY2014032I1 (el) 2015-12-09
RS51607B (sr) 2011-08-31
MXPA05005081A (es) 2005-07-01
CY1110500T1 (el) 2015-04-29
WO2004045618A3 (de) 2004-09-30
NL300650I2 (nl) 2017-11-02
KR101092247B1 (ko) 2011-12-12
NZ540661A (en) 2007-12-21
HUS1400011I1 (hu) 2022-02-28
AU2003285326A1 (en) 2004-06-15
LU92433I2 (fr) 2014-06-24
AR087241A2 (es) 2014-03-12
UA81276C2 (en) 2007-12-25
HRP20050432B1 (en) 2012-01-31

Similar Documents

Publication Publication Date Title
HUS1400011I1 (hu) Új gyógyszer krónikus elzáródásos tüdõbetegség kezelésére
AU2003291992A1 (en) Phenylethanolamine derivatives for the treatment of respiratory diseases
PT1556342E (pt) Derivado de fenetanolamina para o tratamento de doenças respiratórias
AU2003279338A1 (en) Phenethanolamine derivatives for the treatment of respiratory diseases
ZA200703601B (en) Medicaments for the treatment or prevention of fibriotic diseases
SI1656346T1 (sl) 1,2,3,4-tetrasubstituiran indol za zdravljenje respiratornih bolezni
AU2003285091A8 (en) Interferon antagonists useful for the treatment of interferon related diseases
IL179906A0 (en) Novel hydantoin derivatives for the treatment of obstructive airway diseases
SI1530466T1 (sl) Uporaba nintedaniba za zdravljenje pljučne fibroze
TWI372056B (en) Novel medicament combinations for the treatment of respiratory diseases
GB0410398D0 (en) The treatment of respiratory disease
AU2002338303A1 (en) Therapeutic compositions for the treatment of a respiratory tract disease
HU0102388D0 (en) Diazepinoindoles for the treatment of chronic obstructive pulmonary disease
IL163871A0 (en) Diclofenac-based composition for the topical treatment of oropharyngeal cavity disorders
AU2003294100A8 (en) Use of hyaluronic acid for respiratory disorders or the upper airways
AU2003205898A1 (en) Combination therapy for respiratory disorders
HRP20041160A2 (en) Novel combination for the treatment of airway disorders
AU2003209542A8 (en) Use of s-substituted l-crysteine for the manufacture of a medicament for the treatment of dermatological disorders
AU2003269257A1 (en) Use of cap-1 for the therapy of asthma
AU4335901A (en) Novel therapeutic treatment of chronic obstructive pulmonary disease
GB0201025D0 (en) The treatment of degenerative diseases
HRP20041159A2 (en) Combination for the treatment of airway disorders
AU2003252479A1 (en) Remedies for respiratory diseases
AU2003301395A1 (en) Therapeutic agent for chronic obstructive pulmonary disease
GB0224330D0 (en) Treatment of respiratory disorders