JP4262606B2 - Ｎｍｄａ、５ｈｔ３及び神経性ニコチンレセプターアンタゴニストとしてのアミノシクロヘキサンのアザ二環状、アザ三環状及びアザスピロ環状誘導体 - Google Patents

Ｎｍｄａ、５ｈｔ３及び神経性ニコチンレセプターアンタゴニストとしてのアミノシクロヘキサンのアザ二環状、アザ三環状及びアザスピロ環状誘導体 Download PDF

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JP4262606B2
JP4262606B2 JP2003577874A JP2003577874A JP4262606B2 JP 4262606 B2 JP4262606 B2 JP 4262606B2 JP 2003577874 A JP2003577874 A JP 2003577874A JP 2003577874 A JP2003577874 A JP 2003577874A JP 4262606 B2 JP4262606 B2 JP 4262606B2
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hydrochloride
azabicyclo
exo
octane
group
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JP2005525385A (ja
JP2005525385A5 (https=
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パーソンズ・クリストファー・グラハム・ラファエル
ヘンリヒ・マルクス
ダニシュツ・ヴォイシィチ
カルヴィンシュ・イヴァース
カオス・ヴァラーヤンス
イルゲンソンス・アイガース
ゴルト・マルクス
ヴァネイエフス・マクシムス
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メルツ・ファルマ・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト・アウフ・アクティーン
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JP2003577874A 2002-03-21 2003-03-21 Ｎｍｄａ、５ｈｔ３及び神経性ニコチンレセプターアンタゴニストとしてのアミノシクロヘキサンのアザ二環状、アザ三環状及びアザスピロ環状誘導体 Expired - Fee Related JP4262606B2 (ja)

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US36638602P 2002-03-21 2002-03-21
PCT/GB2003/001236 WO2003080046A1 (en) 2002-03-21 2003-03-21 Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane nmda, 5ht3, and neuronal nicotinic receptor antagoni sts

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JP2005525385A JP2005525385A (ja) 2005-08-25
JP2005525385A5 JP2005525385A5 (https=) 2009-01-15
JP4262606B2 true JP4262606B2 (ja) 2009-05-13

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US (4) US7022729B2 (https=)
EP (1) EP1485086A1 (https=)
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KR (1) KR100741257B1 (https=)
CN (1) CN1638762A (https=)
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ES2483126T3 (es) 2004-06-17 2014-08-05 Merz Pharma Gmbh & Co. Kgaa Formulaciones de formas de dosificación de neramexano
US20060205822A1 (en) * 2004-12-22 2006-09-14 Forest Laboratories, Inc. 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect
EP2111858A1 (en) 2008-04-25 2009-10-28 EPFL Ecole Polytechnique Fédérale de Lausanne Novel treatment for alzheimer's disease
US20090275597A1 (en) * 2008-05-02 2009-11-05 Forest Laboratories Holdings Limited Methods of treating cns disorders
PE20130775A1 (es) * 2010-05-27 2013-07-21 Targacept Inc Antagonistas no competitivos de receptores nicotinicos
RU2014122338A (ru) * 2011-11-03 2015-12-10 Таргасепт, Инк. Неконкурентные модуляторы никотиновых рецепторов
JP6095122B2 (ja) * 2012-01-25 2017-03-15 国立大学法人東北大学 脳機能改善剤
PE20151727A1 (es) 2013-03-14 2015-12-17 Boehringer Ingelheim Int Acido 2-aza-biciclo[2.2.1]heptano-3-carboxilico (bencil-ciano-metil)-amidas sustituidas inhibidores de catepsina c
KR102510588B1 (ko) 2014-09-12 2023-03-17 베링거 인겔하임 인터내셔날 게엠베하 카텝신 c의 스피로사이클릭 억제제

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IL164041A0 (en) 2005-12-18
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ZA200406940B (en) 2005-09-22
US7238703B2 (en) 2007-07-03
AR039008A1 (es) 2005-02-02
KR100741257B1 (ko) 2007-07-19
PL372701A1 (en) 2005-07-25
WO2003080046A1 (en) 2003-10-02
AU2003216855A1 (en) 2003-10-08
US20060019983A1 (en) 2006-01-26
UA77778C2 (en) 2007-01-15
KR20040091005A (ko) 2004-10-27
JP2005525385A (ja) 2005-08-25
US20040034055A1 (en) 2004-02-19
CN1638762A (zh) 2005-07-13
US20060019982A1 (en) 2006-01-26
US20070185151A1 (en) 2007-08-09
CO5611104A2 (es) 2006-02-28
EP1485086A1 (en) 2004-12-15
US7022729B2 (en) 2006-04-04
EA007098B1 (ru) 2006-06-30
TW200306189A (en) 2003-11-16
GEP20063954B (en) 2006-10-25
NO20044481L (no) 2004-10-20
CA2474637A1 (en) 2003-10-02
MXPA04007755A (es) 2004-10-15

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