JP4216716B2 - クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 - Google Patents

クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 Download PDF

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JP4216716B2
JP4216716B2 JP2003519572A JP2003519572A JP4216716B2 JP 4216716 B2 JP4216716 B2 JP 4216716B2 JP 2003519572 A JP2003519572 A JP 2003519572A JP 2003519572 A JP2003519572 A JP 2003519572A JP 4216716 B2 JP4216716 B2 JP 4216716B2
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hybrid
group
particles
monolithic material
surface modifier
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JP2004538468A5 (enExample
JP2004538468A (ja
Inventor
ウォルター,トーマス・エイチ
ディング,ジュリア
ケレ,マリアンナ
オーガラ,ジョン・イー
イラニータ,パメラ・シー
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ウォーターズ・インヴェストメンツ・リミテッド
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/02Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/103Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/262Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • BPERFORMING OPERATIONS; TRANSPORTING
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    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/264Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
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    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033Membrane, sheet, cloth, pad, lamellar or mat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
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    • B01J20/28069Pore volume, e.g. total pore volume, mesopore volume, micropore volume
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    • B01J20/28078Pore diameter
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    • B01J20/3225Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating involving a post-treatment of the coated or impregnated product
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    • DTEXTILES; PAPER
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
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    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2993Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995Silane, siloxane or silicone coating

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Textile Engineering (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Silicon Polymers (AREA)
JP2003519572A 2001-08-09 2002-08-08 クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法 Expired - Fee Related JP4216716B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31144501P 2001-08-09 2001-08-09
PCT/US2002/025193 WO2003014450A1 (en) 2001-08-09 2002-08-08 Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation

Related Child Applications (1)

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JP2008236842A Division JP5089543B2 (ja) 2001-08-09 2008-09-16 クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法

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Publication Number Publication Date
JP2004538468A JP2004538468A (ja) 2004-12-24
JP2004538468A5 JP2004538468A5 (enExample) 2006-01-05
JP4216716B2 true JP4216716B2 (ja) 2009-01-28

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JP2008236842A Expired - Lifetime JP5089543B2 (ja) 2001-08-09 2008-09-16 クロマトグラフィー分離用多孔質有機・無機ハイブリッドモノリス状物質、およびその製造方法

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US (3) US7250214B2 (enExample)
EP (1) EP1417366A4 (enExample)
JP (2) JP4216716B2 (enExample)
WO (1) WO2003014450A1 (enExample)

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US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US7250214B2 (en) 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
EP1562700A1 (de) * 2002-10-31 2005-08-17 MERCK PATENT GmbH Mit organischen polymeren beschichtete anorganische monolithische formk rper
JP4791352B2 (ja) * 2003-02-07 2011-10-12 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフィーナノカラム用ポリマー固体支持体
DE112004000244T5 (de) * 2003-02-10 2006-02-09 Waters Investments Ltd., New Castle Siloxan-immobilisierte partikuläre stationäre Phasen für chromatographische Auftrennungen und Extraktionen
DE112004000906T5 (de) * 2003-05-28 2006-10-19 Waters Investments Ltd., New Castle Neue Nanoverbundstoffe und ihre Anwendung als Monolithsäulen
WO2005007264A2 (en) * 2003-07-14 2005-01-27 Waters Investments Limited Separation device with integral guard column
DE10351798A1 (de) * 2003-11-06 2005-06-09 Merck Patent Gmbh Verfahren zur Herstellung von monolithischen Formkörpern
US20050127002A1 (en) * 2003-12-12 2005-06-16 Zare Richard N. Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
DE112005000269T5 (de) * 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen
GB2428393B (en) 2004-03-05 2008-10-01 Waters Investments Ltd Frit for high pressure liquid chromotography
US7309426B2 (en) * 2004-04-23 2007-12-18 Agilent Technologies, Inc. Composition and method for high efficiency chromatography
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