JP2742568B2 - 燐酸マイトマイシン誘導体 - Google Patents

燐酸マイトマイシン誘導体

Info

Publication number
JP2742568B2
JP2742568B2 JP1164084A JP16408489A JP2742568B2 JP 2742568 B2 JP2742568 B2 JP 2742568B2 JP 1164084 A JP1164084 A JP 1164084A JP 16408489 A JP16408489 A JP 16408489A JP 2742568 B2 JP2742568 B2 JP 2742568B2
Authority
JP
Japan
Prior art keywords
mitomycin
compound
iia
salt
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP1164084A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0248588A (ja
Inventor
デイ センター ピーター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPH0248588A publication Critical patent/JPH0248588A/ja
Application granted granted Critical
Publication of JP2742568B2 publication Critical patent/JP2742568B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP1164084A 1988-06-29 1989-06-28 燐酸マイトマイシン誘導体 Expired - Fee Related JP2742568B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/213,201 US4874779A (en) 1988-06-29 1988-06-29 Mitomycin phosphate derivatives
US213201 1988-06-29

Publications (2)

Publication Number Publication Date
JPH0248588A JPH0248588A (ja) 1990-02-19
JP2742568B2 true JP2742568B2 (ja) 1998-04-22

Family

ID=22794125

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1164084A Expired - Fee Related JP2742568B2 (ja) 1988-06-29 1989-06-28 燐酸マイトマイシン誘導体

Country Status (31)

Country Link
US (1) US4874779A (enExample)
JP (1) JP2742568B2 (enExample)
KR (1) KR0145088B1 (enExample)
AT (1) AT398203B (enExample)
AU (1) AU606288B2 (enExample)
BE (1) BE1002655A3 (enExample)
CA (1) CA1334671C (enExample)
CH (1) CH678728A5 (enExample)
CY (1) CY1815A (enExample)
DD (1) DD284017A5 (enExample)
DE (1) DE3921022B4 (enExample)
DK (1) DK168293B1 (enExample)
ES (1) ES2016032A6 (enExample)
FI (1) FI90982C (enExample)
FR (1) FR2633625B1 (enExample)
GB (1) GB2220205B (enExample)
GR (1) GR1000955B (enExample)
HK (1) HK39695A (enExample)
HU (1) HU202245B (enExample)
IE (1) IE62363B1 (enExample)
IL (1) IL90751A (enExample)
IT (1) IT1230166B (enExample)
LU (1) LU87543A1 (enExample)
MY (1) MY104044A (enExample)
NL (1) NL194916C (enExample)
NO (1) NO176103C (enExample)
NZ (1) NZ229650A (enExample)
PT (1) PT91004B (enExample)
SE (1) SE468770B (enExample)
YU (1) YU132689A (enExample)
ZA (1) ZA894875B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552154A (en) 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
US5091523A (en) * 1990-04-25 1992-02-25 Georgetown University Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof
US6080751A (en) * 1992-01-14 2000-06-27 The Stehlin Foundation For Cancer Research Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
US6098229A (en) * 1998-09-17 2000-08-08 Ward; William Kevin Grill cleaning apparatus
DE60222745T2 (de) * 2001-03-08 2008-07-10 Nymox Pharmaceutical Corp., St. Laurent Verwendung von neurofilamentproteinen zur behandlung von tumoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1090707A (en) * 1965-11-05 1967-11-15 Kyowa Hakko Kogyo Kk Mitomycin c derivatives
FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体

Also Published As

Publication number Publication date
IL90751A (en) 1994-01-25
DE3921022B4 (de) 2004-02-26
SE8902340D0 (sv) 1989-06-28
GB2220205A (en) 1990-01-04
FI893115A0 (fi) 1989-06-26
GR890100421A (en) 1991-11-15
NL194916B (nl) 2003-03-03
IL90751A0 (en) 1990-01-18
HUT51638A (en) 1990-05-28
FI90982C (fi) 1994-04-25
IE62363B1 (en) 1995-01-25
FI893115L (fi) 1989-12-30
DD284017A5 (de) 1990-10-31
NL194916C (nl) 2003-07-04
IE892104L (en) 1989-12-29
SE8902340L (sv) 1989-12-30
NL8901623A (nl) 1990-01-16
FR2633625B1 (fr) 1991-11-15
AU3721789A (en) 1990-01-04
CA1334671C (en) 1995-03-07
ES2016032A6 (es) 1990-10-01
YU132689A (en) 1991-04-30
GR1000955B (el) 1993-03-16
FR2633625A1 (fr) 1990-01-05
NO176103B (no) 1994-10-24
BE1002655A3 (fr) 1991-04-23
DK168293B1 (da) 1994-03-07
KR910000738A (ko) 1991-01-30
PT91004B (pt) 1994-11-30
IT8921023A0 (it) 1989-06-28
KR0145088B1 (ko) 1998-07-15
PT91004A (pt) 1989-12-29
SE468770B (sv) 1993-03-15
ZA894875B (en) 1990-05-30
HU202245B (en) 1991-02-28
DE3921022A1 (de) 1990-03-15
JPH0248588A (ja) 1990-02-19
IT1230166B (it) 1991-10-14
FI90982B (fi) 1994-01-14
MY104044A (en) 1993-10-30
NZ229650A (en) 1991-10-25
CH678728A5 (enExample) 1991-10-31
NO176103C (no) 1995-02-01
AT398203B (de) 1994-10-25
ATA155589A (de) 1994-02-15
GB8914848D0 (en) 1989-08-16
CY1815A (en) 1995-10-20
AU606288B2 (en) 1991-01-31
US4874779A (en) 1989-10-17
LU87543A1 (fr) 1990-02-28
DK318789A (da) 1989-12-30
NO892688D0 (no) 1989-06-28
GB2220205B (en) 1991-10-16
DK318789D0 (da) 1989-06-27
HK39695A (en) 1995-03-31
NO892688L (no) 1990-01-02

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees