JP2021521192A - セレブロンリガンドおよび同リガンドを含む二機能性化合物 - Google Patents

セレブロンリガンドおよび同リガンドを含む二機能性化合物 Download PDF

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JP2021521192A
JP2021521192A JP2020555835A JP2020555835A JP2021521192A JP 2021521192 A JP2021521192 A JP 2021521192A JP 2020555835 A JP2020555835 A JP 2020555835A JP 2020555835 A JP2020555835 A JP 2020555835A JP 2021521192 A JP2021521192 A JP 2021521192A
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syndrome
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optionally substituted
disease
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JPWO2019199816A5 (enExample
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アンドリュー ピー． クルー，
アンドリュー ピー． クルー，
クレイグ エム． クルーズ，
クレイグ エム． クルーズ，
ハンチン ドン，
ハンチン ドン，
キース アール． ホーンバーガー，
キース アール． ホーンバーガー，
ジン ワン，
ジン ワン，
イミン チアン，
イミン チアン，
カート ジマーマン，
カート ジマーマン，
マイケル バーリン，
マイケル バーリン，
ローレンス ビー． スナイダー，
ローレンス ビー． スナイダー，
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Arvinas Operations Inc
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Arvinas Operations Inc
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Priority claimed from US15/953,108 external-priority patent/US20180228907A1/en
Application filed by Arvinas Operations Inc filed Critical Arvinas Operations Inc
Publication of JP2021521192A publication Critical patent/JP2021521192A/ja
Publication of JPWO2019199816A5 publication Critical patent/JPWO2019199816A5/ja
Priority to JP2023174374A priority Critical patent/JP7748432B2/ja
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JP2020555835A 2018-04-13 2019-04-09 セレブロンリガンドおよび同リガンドを含む二機能性化合物 Pending JP2021521192A (ja)

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US15/953,108 US20180228907A1 (en) 2014-04-14 2018-04-13 Cereblon ligands and bifunctional compounds comprising the same
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PCT/US2019/026570 WO2019199816A1 (en) 2018-04-13 2019-04-09 Cereblon ligands and bifunctional compounds comprising the same

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US20180228907A1 (en) 2014-04-14 2018-08-16 Arvinas, Inc. Cereblon ligands and bifunctional compounds comprising the same
CA3042260C (en) 2016-11-01 2023-10-03 Arvinas, Inc. Tau-protein targeting protacs and associated methods of use
CN110769822A (zh) 2017-06-20 2020-02-07 C4医药公司 用于蛋白降解的n/o-连接的降解决定子和降解决定子体
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