CN112262134B - 小脑蛋白配体和包括其的双官能化合物 - Google Patents

小脑蛋白配体和包括其的双官能化合物 Download PDF

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CN112262134B
CN112262134B CN201980036235.7A CN201980036235A CN112262134B CN 112262134 B CN112262134 B CN 112262134B CN 201980036235 A CN201980036235 A CN 201980036235A CN 112262134 B CN112262134 B CN 112262134B
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optionally substituted
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protein
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CN112262134A (zh
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A·P·克鲁
C·M·克鲁斯
董汉清
K·R·霍恩伯格
王警
钱义民
K·齐默尔曼
M·伯林
L·B·斯奈德
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Arvinas Inc
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CN201980036235.7A 2018-04-13 2019-04-09 小脑蛋白配体和包括其的双官能化合物 Active CN112262134B (zh)

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US15/953,108 US20180228907A1 (en) 2014-04-14 2018-04-13 Cereblon ligands and bifunctional compounds comprising the same
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PCT/US2019/026570 WO2019199816A1 (en) 2018-04-13 2019-04-09 Cereblon ligands and bifunctional compounds comprising the same

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CN110769822A (zh) 2017-06-20 2020-02-07 C4医药公司 用于蛋白降解的n/o-连接的降解决定子和降解决定子体
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WO2019191112A1 (en) 2018-03-26 2019-10-03 C4 Therapeutics, Inc. Cereblon binders for the degradation of ikaros
EP3781156A4 (en) 2018-04-16 2022-05-18 C4 Therapeutics, Inc. SPIROCYCLIC COMPOUNDS
EA202092436A1 (ru) 2018-05-14 2021-05-04 Нувейшн Био Инк. Противораковые соединения, нацеливающие на ядерные гормональные рецепторы
CA3103185A1 (en) 2018-06-13 2019-12-19 Amphista Therapeutics Ltd Bifunctional molecules for targeting rpn11
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