JP2021500551A5 - - Google Patents
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- Publication number
- JP2021500551A5 JP2021500551A5 JP2020521964A JP2020521964A JP2021500551A5 JP 2021500551 A5 JP2021500551 A5 JP 2021500551A5 JP 2020521964 A JP2020521964 A JP 2020521964A JP 2020521964 A JP2020521964 A JP 2020521964A JP 2021500551 A5 JP2021500551 A5 JP 2021500551A5
- Authority
- JP
- Japan
- Prior art keywords
- sdma
- antibody
- solid matrix
- affinity
- capture reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HVPFXCBJHIIJGS-LURJTMIESA-N N(omega),N'(omega)-dimethyl-L-arginine Chemical compound CN\C(=N/C)NCCC[C@H](N)C(O)=O HVPFXCBJHIIJGS-LURJTMIESA-N 0.000 claims 25
- 239000011159 matrix material Substances 0.000 claims 25
- 239000007787 solid Substances 0.000 claims 20
- 239000003153 chemical reaction reagent Substances 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 15
- 102000004169 proteins and genes Human genes 0.000 claims 13
- 108090000623 proteins and genes Proteins 0.000 claims 13
- 239000002245 particle Substances 0.000 claims 12
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 11
- 150000001483 arginine derivatives Chemical class 0.000 claims 9
- 102100031126 6-phosphogluconolactonase Human genes 0.000 claims 8
- 108010029731 6-phosphogluconolactonase Proteins 0.000 claims 8
- 108010018962 Glucosephosphate Dehydrogenase Proteins 0.000 claims 8
- YDGMGEXADBMOMJ-LURJTMIESA-N N(g)-dimethylarginine Chemical compound CN(C)C(\N)=N\CCC[C@H](N)C(O)=O YDGMGEXADBMOMJ-LURJTMIESA-N 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 239000007790 solid phase Substances 0.000 claims 8
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 6
- NTWVQPHTOUKMDI-YFKPBYRVSA-N N-Methyl-arginine Chemical compound CN[C@H](C(O)=O)CCCN=C(N)N NTWVQPHTOUKMDI-YFKPBYRVSA-N 0.000 claims 6
- 229940098773 bovine serum albumin Drugs 0.000 claims 6
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 6
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 4
- 108010058846 Ovalbumin Proteins 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 3
- 229940092253 ovalbumin Drugs 0.000 claims 3
- 238000005406 washing Methods 0.000 claims 3
- 230000010933 acylation Effects 0.000 claims 2
- 238000005917 acylation reaction Methods 0.000 claims 2
- YDGMGEXADBMOMJ-UHFFFAOYSA-N asymmetrical dimethylarginine Natural products CN(C)C(N)=NCCCC(N)C(O)=O YDGMGEXADBMOMJ-UHFFFAOYSA-N 0.000 claims 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762574592P | 2017-10-19 | 2017-10-19 | |
| US62/574,592 | 2017-10-19 | ||
| US201762599117P | 2017-12-15 | 2017-12-15 | |
| US62/599,117 | 2017-12-15 | ||
| PCT/US2018/056687 WO2019079707A1 (en) | 2017-10-19 | 2018-10-19 | SYMMETRIC DIMETHYLARGININE DETECTION |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500551A JP2021500551A (ja) | 2021-01-07 |
| JP2021500551A5 true JP2021500551A5 (enExample) | 2021-11-25 |
| JP7398366B2 JP7398366B2 (ja) | 2023-12-14 |
Family
ID=66170983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020521964A Active JP7398366B2 (ja) | 2017-10-19 | 2018-10-19 | 対称性ジメチルアルギニンの検出 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11422136B2 (enExample) |
| EP (1) | EP3697499A4 (enExample) |
| JP (1) | JP7398366B2 (enExample) |
| KR (1) | KR20250034534A (enExample) |
| CN (1) | CN111246918B (enExample) |
| AU (1) | AU2018351349B2 (enExample) |
| CA (1) | CA3079011A1 (enExample) |
| MX (1) | MX2020003523A (enExample) |
| TW (1) | TWI831753B (enExample) |
| WO (1) | WO2019079707A1 (enExample) |
| ZA (1) | ZA202002415B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8481690B2 (en) * | 2008-08-07 | 2013-07-09 | Idexx Laboratories, Inc. | Methods for detecting symmetrical dimethylarginine |
| FI3259593T3 (fi) * | 2015-02-20 | 2023-01-13 | Homogeeninen immunomääritys, jossa on taustasignaalikompensointi | |
| AU2018351349B2 (en) * | 2017-10-19 | 2025-08-14 | Idexx Laboratories, Inc. | Detection of symmetrical dimethylarginine |
| US10745492B1 (en) * | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
| EP4025301A4 (en) | 2019-09-05 | 2023-07-19 | The Regents of the University of California | NON-INVASIVE METHOD FOR QUANTIFYING KIDNEY FUNCTION AND FUNCTIONAL DECLINE |
| CN113125697B (zh) * | 2019-12-31 | 2024-03-26 | 科美博阳诊断技术(上海)有限公司 | 一种睾酮均相化学发光检测试剂盒及其应用 |
| EP4136141A4 (en) * | 2020-04-17 | 2024-09-11 | IDEXX Laboratories, Inc. | Fluorescence quenching immunossay |
| EP4263383A4 (en) | 2020-12-17 | 2024-10-23 | Nephrosant, Inc. | KITS FOR STABILIZATION OF URINE SAMPLES |
| WO2025070448A1 (ja) * | 2023-09-26 | 2025-04-03 | 富士フイルム株式会社 | 対称性ジメチルアルギニンを測定するためのキットおよび対称性ジメチルアルギニンの測定方法 |
| WO2025205769A1 (ja) * | 2024-03-26 | 2025-10-02 | 富士フイルム株式会社 | α－アミラーゼと対称性ジメチルアルギニンとのコンジュゲート、およびその応用 |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3875011A (en) | 1972-11-06 | 1975-04-01 | Syva Co | Enzyme immunoassays with glucose-6-phosphate dehydrogenase |
| DE3134787A1 (de) | 1981-09-02 | 1983-03-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Creatinin-antikoerper |
| IT1199088B (it) | 1984-03-09 | 1988-12-30 | Miles Italiana | Saggio di legame specifico mediante impiego di anti-g6pdh come marcante |
| US4818703A (en) | 1985-10-23 | 1989-04-04 | Pizzolante John M | Stabilized alkaline picrate reagent for jaffe creatinine determination |
| EP0356160A3 (en) | 1988-08-24 | 1991-09-11 | The Board Of Trustees Of The Leland Stanford Junior University | Capillary device |
| US5238652A (en) * | 1990-06-20 | 1993-08-24 | Drug Screening Systems, Inc. | Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques |
| US5726010A (en) | 1991-07-31 | 1998-03-10 | Idexx Laboratories, Inc. | Reversible flow chromatographic binding assay |
| US6455288B1 (en) | 1993-04-08 | 2002-09-24 | Dade Behring Marburg Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
| US5710009A (en) * | 1994-02-17 | 1998-01-20 | Serex, Inc. | Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon |
| US5804452A (en) | 1995-04-27 | 1998-09-08 | Quidel Corporation | One step urine creatinine assays |
| AU7269098A (en) | 1997-05-01 | 1998-11-24 | Cooke Pharma, Inc. | Cardiovascular disease risk assessment |
| US6736957B1 (en) | 1997-10-16 | 2004-05-18 | Abbott Laboratories | Biosensor electrode mediators for regeneration of cofactors and process for using |
| US6358699B1 (en) | 1999-02-05 | 2002-03-19 | Cooke Pharma | Assay for asymmetrical NG, NG dimethyl-l-arginine |
| WO2001046221A1 (en) | 1999-12-22 | 2001-06-28 | The Research Foundation Of State University Of New York | Protein methylarginine-specific antibodies |
| WO2002004465A1 (en) | 2000-07-06 | 2002-01-17 | Fal Diagnostics | Methods and kits for the detection of arginine compounds |
| WO2002004950A2 (en) | 2000-07-12 | 2002-01-17 | Werner Naser | Direct assessment of analyte to reference molecule ratios |
| DE10040904A1 (de) | 2000-08-18 | 2002-02-28 | Boeger Rainer H | Verfahren und Mittel zum Nachweis einer Wahrscheinlichkeit zukünftigen Fortschreitens von Gefässerkrankungen |
| US7241856B2 (en) | 2003-06-02 | 2007-07-10 | Pentron Clinical Technologies Llc | Dental resins, dental composite materials, and method of manufacture thereof |
| FR2824825B1 (fr) | 2001-05-15 | 2005-05-06 | Servier Lab | Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP4214271B2 (ja) | 2002-10-15 | 2009-01-28 | アークレイ株式会社 | クレアチニン測定用試験片 |
| US7501053B2 (en) | 2002-10-23 | 2009-03-10 | Abbott Laboratories | Biosensor having improved hematocrit and oxygen biases |
| AU2003290784A1 (en) | 2002-11-15 | 2004-06-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for detecting asymmetric dimethylarginine in a biological sample |
| JP2004279412A (ja) * | 2003-02-24 | 2004-10-07 | Sanwa Kagaku Kenkyusho Co Ltd | 低分子化合物の免疫学的測定・検出方法 |
| US20050148029A1 (en) | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
| WO2005098439A2 (en) * | 2004-03-30 | 2005-10-20 | Whatman, Inc. | Lateral flow format, materials and mehtods |
| DE602004020360D1 (de) | 2004-11-04 | 2009-05-14 | Germediq Forsch & Entw Ges Mbh | Methode zur Bestimmung von Arginin, methylierten Argininen und deren Derivate |
| CN1786713A (zh) * | 2004-12-09 | 2006-06-14 | 陈金华 | 酶标仪在胶乳增强免疫透射比浊法中的应用 |
| US7879979B2 (en) * | 2005-01-21 | 2011-02-01 | Alere International | Arginine analogs, and methods for their synthesis and use |
| AU2006239315B2 (en) * | 2005-04-28 | 2012-03-01 | Ventana Medical Systems, Inc. | Enzymes conjugated to antiobodies via a PEG heterobifuctional linker |
| DE102005060057A1 (de) | 2005-12-15 | 2007-06-28 | Kellner, Karl-Heinz, Dr. | Sandwich-Immunoassay für kleine Haptenmoleküle |
| JP2007176872A (ja) | 2005-12-28 | 2007-07-12 | Sentan Seimei Kagaku Kenkyusho:Kk | アシンメトリックジメチルアルギニンを認識する抗体及びその製造方法並びに翻訳後修飾アミノ酸含有タンパク質の検出方法 |
| FR2919063B1 (fr) | 2007-07-19 | 2009-10-02 | Biomerieux Sa | Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal. |
| CN101932722A (zh) | 2007-12-05 | 2010-12-29 | 伦敦王室学院 | 方法和组合物 |
| US8481690B2 (en) | 2008-08-07 | 2013-07-09 | Idexx Laboratories, Inc. | Methods for detecting symmetrical dimethylarginine |
| US20120129265A1 (en) | 2009-06-02 | 2012-05-24 | Biocrates Life Sciences Ag | New biomarkers for assessing kidney diseases |
| CN101587118B (zh) | 2009-07-03 | 2012-09-12 | 长春迪瑞医疗科技股份有限公司 | 肌酐尿液分析试纸及制备方法 |
| CN101598727B (zh) | 2009-07-09 | 2012-10-10 | 上海科华生物工程股份有限公司 | 定量测定人体血液尿素含量的干化学试纸 |
| CN101865911A (zh) | 2010-03-16 | 2010-10-20 | 苏州市玮琪生物科技有限公司 | 一种尿肌酐定量检测卡 |
| JP5974892B2 (ja) | 2010-08-31 | 2016-08-23 | コニカミノルタ株式会社 | 生体物質検出方法 |
| EP2612147B1 (de) | 2010-11-17 | 2016-03-30 | Karl-Heinz Kellner | Automatenfähiger immunoassay für biogene amine |
| JP2012112785A (ja) | 2010-11-24 | 2012-06-14 | Tohoku Univ | 透析膜の評価方法 |
| US8394647B2 (en) * | 2011-02-17 | 2013-03-12 | Siemens Healthcare Diagnostics Inc. | Reducing non-covalently bound polysaccharide on supports |
| CN102628868B (zh) * | 2011-12-30 | 2014-09-17 | 北京九强生物技术股份有限公司 | 检测非对称二甲基精氨酸含量的胶乳增强免疫比浊法试剂盒 |
| CA2857522C (en) * | 2012-01-10 | 2020-04-14 | Idexx Laboratories, Inc. | Immunoassay test slide |
| US20140038203A1 (en) | 2012-07-09 | 2014-02-06 | Musc Foundation For Research Development | Methods for detecting or predicting kidney disease |
| PL2888257T3 (pl) | 2012-08-21 | 2018-02-28 | Janssen Pharmaceutica Nv | Hapteny kwetiapiny do zastosowania w testach immunologicznych |
| RS59287B1 (sr) | 2013-09-05 | 2019-10-31 | Idexx Lab Inc | Postupci za otkrivanje bolesti bubrega |
| FI3259593T3 (fi) | 2015-02-20 | 2023-01-13 | Homogeeninen immunomääritys, jossa on taustasignaalikompensointi | |
| AU2018351349B2 (en) | 2017-10-19 | 2025-08-14 | Idexx Laboratories, Inc. | Detection of symmetrical dimethylarginine |
| CN108469419A (zh) * | 2018-03-09 | 2018-08-31 | 山东泰邦生物制品有限公司 | 采用酶标仪免疫透射比浊法高通量检测IgG含量的方法 |
-
2018
- 2018-10-19 AU AU2018351349A patent/AU2018351349B2/en active Active
- 2018-10-19 WO PCT/US2018/056687 patent/WO2019079707A1/en not_active Ceased
- 2018-10-19 EP EP18868800.6A patent/EP3697499A4/en active Pending
- 2018-10-19 JP JP2020521964A patent/JP7398366B2/ja active Active
- 2018-10-19 TW TW107136895A patent/TWI831753B/zh active
- 2018-10-19 KR KR1020257007101A patent/KR20250034534A/ko active Pending
- 2018-10-19 CA CA3079011A patent/CA3079011A1/en active Pending
- 2018-10-19 US US16/165,337 patent/US11422136B2/en active Active
- 2018-10-19 MX MX2020003523A patent/MX2020003523A/es unknown
- 2018-10-19 CN CN201880068370.5A patent/CN111246918B/zh active Active
-
2020
- 2020-05-04 ZA ZA2020/02415A patent/ZA202002415B/en unknown
-
2022
- 2022-07-29 US US17/877,410 patent/US20230102277A1/en active Pending
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