MX2020003523A - Deteccion de dimetilarginina simetrica. - Google Patents

Deteccion de dimetilarginina simetrica.

Info

Publication number
MX2020003523A
MX2020003523A MX2020003523A MX2020003523A MX2020003523A MX 2020003523 A MX2020003523 A MX 2020003523A MX 2020003523 A MX2020003523 A MX 2020003523A MX 2020003523 A MX2020003523 A MX 2020003523A MX 2020003523 A MX2020003523 A MX 2020003523A
Authority
MX
Mexico
Prior art keywords
detection
symmetrical dimethylarginine
dimethylarginine
symmetrical
empty
Prior art date
Application number
MX2020003523A
Other languages
English (en)
Inventor
Hongzhi Xie
Sreenivasa Rao Ramisetty
Murthy Vsn Yerramilli
Original Assignee
Idexx Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idexx Lab Inc filed Critical Idexx Lab Inc
Publication of MX2020003523A publication Critical patent/MX2020003523A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La descripción se relaciona de manera general con la detección de dimetilarginina simétrica (SDMA). Más particularmente, la descripción se relaciona con la detección de SDMA usando una fase sólida. La descripción proporciona dispositivos, reactivos, kits y métodos para detectar dimetilarginina simétrica (SDMA) en una muestra, como por ejemplo una muestra biológica de un animal. El método incluye detectar la presencia o cantidad de SDMA en la muestra mediante el uso de un formato de inmunoensayo, como por ejemplo inmunoensayo competitivo. El ensayo incluye el uso de anticuerpos para SDMA y que son específicos para SDMA y que tienen menos afinidad por otros derivados de arginina.
MX2020003523A 2017-10-19 2018-10-19 Deteccion de dimetilarginina simetrica. MX2020003523A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762574592P 2017-10-19 2017-10-19
US201762599117P 2017-12-15 2017-12-15
PCT/US2018/056687 WO2019079707A1 (en) 2017-10-19 2018-10-19 SYMMETRIC DIMETHYLARGININE DETECTION

Publications (1)

Publication Number Publication Date
MX2020003523A true MX2020003523A (es) 2020-07-22

Family

ID=66170983

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020003523A MX2020003523A (es) 2017-10-19 2018-10-19 Deteccion de dimetilarginina simetrica.

Country Status (11)

Country Link
US (2) US11422136B2 (es)
EP (1) EP3697499A4 (es)
JP (1) JP7398366B2 (es)
KR (1) KR20200073259A (es)
CN (1) CN111246918A (es)
AU (1) AU2018351349A1 (es)
CA (1) CA3079011A1 (es)
MX (1) MX2020003523A (es)
TW (1) TWI831753B (es)
WO (1) WO2019079707A1 (es)
ZA (1) ZA202002415B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102492243B1 (ko) * 2015-02-20 2023-01-25 아이덱스 래보러토리즈, 인코포레이티드 배경 신호에 대한 보상에 의한 균질 면역검정
KR20200073259A (ko) 2017-10-19 2020-06-23 아이덱스 래보러토리즈, 인코포레이티드 대칭 디메틸아르기닌의 검출
US10745492B1 (en) * 2019-04-03 2020-08-18 Ark Diagnostics, Inc. Antibodies to symmetrically dimethylated arginine analytes and use thereof
EP4025301A4 (en) 2019-09-05 2023-07-19 The Regents of the University of California NON-INVASIVE METHOD FOR QUANTIFYING KIDNEY FUNCTION AND FUNCTIONAL DECLINE
CN113125697B (zh) * 2019-12-31 2024-03-26 科美博阳诊断技术(上海)有限公司 一种睾酮均相化学发光检测试剂盒及其应用
TW202204329A (zh) * 2020-04-17 2022-02-01 美商英代斯實驗公司 螢光淬滅免疫分析

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875011A (en) 1972-11-06 1975-04-01 Syva Co Enzyme immunoassays with glucose-6-phosphate dehydrogenase
DE3134787A1 (de) 1981-09-02 1983-03-10 Boehringer Mannheim Gmbh, 6800 Mannheim Creatinin-antikoerper
IT1199088B (it) 1984-03-09 1988-12-30 Miles Italiana Saggio di legame specifico mediante impiego di anti-g6pdh come marcante
US4818703A (en) 1985-10-23 1989-04-04 Pizzolante John M Stabilized alkaline picrate reagent for jaffe creatinine determination
EP0356160A3 (en) 1988-08-24 1991-09-11 The Board Of Trustees Of The Leland Stanford Junior University Capillary device
US5238652A (en) * 1990-06-20 1993-08-24 Drug Screening Systems, Inc. Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques
US5726010A (en) 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6455288B1 (en) 1993-04-08 2002-09-24 Dade Behring Marburg Gmbh Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases
US5710009A (en) * 1994-02-17 1998-01-20 Serex, Inc. Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon
US5804452A (en) 1995-04-27 1998-09-08 Quidel Corporation One step urine creatinine assays
WO1998049199A1 (en) 1997-05-01 1998-11-05 Panorama Research, Inc. Cardiovascular disease risk assessment
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6358699B1 (en) 1999-02-05 2002-03-19 Cooke Pharma Assay for asymmetrical NG, NG dimethyl-l-arginine
WO2001046221A1 (en) 1999-12-22 2001-06-28 The Research Foundation Of State University Of New York Protein methylarginine-specific antibodies
WO2002004465A1 (en) 2000-07-06 2002-01-17 Fal Diagnostics Methods and kits for the detection of arginine compounds
EP1301790B1 (en) 2000-07-12 2008-04-09 Naser, Werner, Dr. Direct assessment of analyte to reference molecule ratios
DE10040904A1 (de) 2000-08-18 2002-02-28 Boeger Rainer H Verfahren und Mittel zum Nachweis einer Wahrscheinlichkeit zukünftigen Fortschreitens von Gefässerkrankungen
US7241856B2 (en) 2003-06-02 2007-07-10 Pentron Clinical Technologies Llc Dental resins, dental composite materials, and method of manufacture thereof
FR2824825B1 (fr) 2001-05-15 2005-05-06 Servier Lab Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4214271B2 (ja) 2002-10-15 2009-01-28 アークレイ株式会社 クレアチニン測定用試験片
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
WO2004046314A2 (en) 2002-11-15 2004-06-03 The Board Of Trustees Of The Leland Stanford Junior University Methods for detecting asymmetric dimethylarginine in a biological sample
JP2004279412A (ja) * 2003-02-24 2004-10-07 Sanwa Kagaku Kenkyusho Co Ltd 低分子化合物の免疫学的測定・検出方法
US20050148029A1 (en) 2003-09-29 2005-07-07 Biosite, Inc. Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes
CN102768273B (zh) * 2004-03-30 2015-08-26 通用电气医疗集团生物科学公司 侧流格式、材料和方法
ES2332218T3 (es) 2004-11-04 2010-01-29 Germediq Forschungs- Und Entwicklungsgesellschaft Mbh Metodo para la determinacion de arginina, argininas metiladas y sus derivados.
CN1786713A (zh) * 2004-12-09 2006-06-14 陈金华 酶标仪在胶乳增强免疫透射比浊法中的应用
WO2006078813A2 (en) 2005-01-21 2006-07-27 Biosite Incorporated Arginine analogs, and methods for their synthesis and use
CA2609702C (en) * 2005-04-28 2013-05-28 Ventana Medical Systems, Inc. Antibody conjugates via heterobifunctional peg linkers
DE102005060057A1 (de) 2005-12-15 2007-06-28 Kellner, Karl-Heinz, Dr. Sandwich-Immunoassay für kleine Haptenmoleküle
JP2007176872A (ja) 2005-12-28 2007-07-12 Sentan Seimei Kagaku Kenkyusho:Kk アシンメトリックジメチルアルギニンを認識する抗体及びその製造方法並びに翻訳後修飾アミノ酸含有タンパク質の検出方法
FR2919063B1 (fr) 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.
EP2229452B1 (en) 2007-12-05 2015-07-29 King's College London Method for aiding the diagnosis of a disorder
EP3808733A1 (en) * 2008-08-07 2021-04-21 IDEXX Laboratories, Inc. Methods for detecting symmetrical demethylarginine
ES2499415T3 (es) 2009-06-02 2014-09-29 Biocrates Life Sciences Ag Nuevos biomarcadores para la evaluación de enfermedades renales
CN101587118B (zh) 2009-07-03 2012-09-12 长春迪瑞医疗科技股份有限公司 肌酐尿液分析试纸及制备方法
CN101598727B (zh) 2009-07-09 2012-10-10 上海科华生物工程股份有限公司 定量测定人体血液尿素含量的干化学试纸
CN101865911A (zh) 2010-03-16 2010-10-20 苏州市玮琪生物科技有限公司 一种尿肌酐定量检测卡
EP2613138B1 (en) * 2010-08-31 2023-01-18 Konica Minolta, Inc. Biological substance detection method
WO2012065912A1 (de) 2010-11-17 2012-05-24 Karl-Heinz Kellner Automatenfähiger immunoassay für biogene amine
JP2012112785A (ja) 2010-11-24 2012-06-14 Tohoku Univ 透析膜の評価方法
US8394647B2 (en) * 2011-02-17 2013-03-12 Siemens Healthcare Diagnostics Inc. Reducing non-covalently bound polysaccharide on supports
CN102628868B (zh) * 2011-12-30 2014-09-17 北京九强生物技术股份有限公司 检测非对称二甲基精氨酸含量的胶乳增强免疫比浊法试剂盒
AU2013208289B2 (en) 2012-01-10 2016-08-11 Idexx Laboratories, Inc. Immunoassay test slide
US20140038203A1 (en) 2012-07-09 2014-02-06 Musc Foundation For Research Development Methods for detecting or predicting kidney disease
ES2822907T3 (es) 2012-08-21 2021-05-05 Janssen Pharmaceutica Nv Haptenos de quetiapina para su uso en inmunoensayos
WO2015035155A1 (en) * 2013-09-05 2015-03-12 Idexx Laboratories, Inc. Methods for detecting renal disease
KR102492243B1 (ko) 2015-02-20 2023-01-25 아이덱스 래보러토리즈, 인코포레이티드 배경 신호에 대한 보상에 의한 균질 면역검정
KR20200073259A (ko) 2017-10-19 2020-06-23 아이덱스 래보러토리즈, 인코포레이티드 대칭 디메틸아르기닌의 검출
CN108469419A (zh) * 2018-03-09 2018-08-31 山东泰邦生物制品有限公司 采用酶标仪免疫透射比浊法高通量检测IgG含量的方法

Also Published As

Publication number Publication date
TWI831753B (zh) 2024-02-11
JP2021500551A (ja) 2021-01-07
CN111246918A (zh) 2020-06-05
US11422136B2 (en) 2022-08-23
JP7398366B2 (ja) 2023-12-14
EP3697499A4 (en) 2021-07-21
EP3697499A1 (en) 2020-08-26
US20190120856A1 (en) 2019-04-25
WO2019079707A1 (en) 2019-04-25
AU2018351349A1 (en) 2020-04-23
TW201923349A (zh) 2019-06-16
ZA202002415B (en) 2023-09-27
US20230102277A1 (en) 2023-03-30
BR112020007150A2 (pt) 2020-09-24
CA3079011A1 (en) 2019-04-25
KR20200073259A (ko) 2020-06-23

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