JP2009516163A5 - - Google Patents
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- Publication number
- JP2009516163A5 JP2009516163A5 JP2008539499A JP2008539499A JP2009516163A5 JP 2009516163 A5 JP2009516163 A5 JP 2009516163A5 JP 2008539499 A JP2008539499 A JP 2008539499A JP 2008539499 A JP2008539499 A JP 2008539499A JP 2009516163 A5 JP2009516163 A5 JP 2009516163A5
- Authority
- JP
- Japan
- Prior art keywords
- binding partner
- binding
- analyte
- kit according
- hub
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 claims 23
- 239000012491 analyte Substances 0.000 claims 17
- 238000003556 assay Methods 0.000 claims 6
- 230000004931 aggregating effect Effects 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 5
- 238000007818 agglutination assay Methods 0.000 claims 4
- 230000004520 agglutination Effects 0.000 claims 2
- 238000004220 aggregation Methods 0.000 claims 2
- 230000002776 aggregation Effects 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 230000037361 pathway Effects 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108091023037 Aptamer Proteins 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 102000028180 Glycophorins Human genes 0.000 claims 1
- 108091005250 Glycophorins Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 229910000278 bentonite Inorganic materials 0.000 claims 1
- 239000000440 bentonite Substances 0.000 claims 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003610 charcoal Substances 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims 1
- 229910052622 kaolinite Inorganic materials 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 239000008279 sol Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0523124.6 | 2005-11-12 | ||
| GB0523124A GB2432211B (en) | 2005-11-12 | 2005-11-12 | Agglutination based assay system |
| GB0610973A GB0610973D0 (en) | 2006-06-03 | 2006-06-03 | Agglutination assay |
| GB0610973.0 | 2006-06-03 | ||
| PCT/GB2006/004204 WO2007054714A2 (en) | 2005-11-12 | 2006-11-13 | Agglutination assay |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013097647A Division JP2013174612A (ja) | 2005-11-12 | 2013-05-07 | 凝集アッセイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009516163A JP2009516163A (ja) | 2009-04-16 |
| JP2009516163A5 true JP2009516163A5 (enExample) | 2010-01-07 |
| JP5426881B2 JP5426881B2 (ja) | 2014-02-26 |
Family
ID=37797232
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008539499A Expired - Fee Related JP5426881B2 (ja) | 2005-11-12 | 2006-11-13 | 凝集アッセイ |
| JP2013097647A Pending JP2013174612A (ja) | 2005-11-12 | 2013-05-07 | 凝集アッセイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013097647A Pending JP2013174612A (ja) | 2005-11-12 | 2013-05-07 | 凝集アッセイ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9201065B2 (enExample) |
| EP (2) | EP2674757A3 (enExample) |
| JP (2) | JP5426881B2 (enExample) |
| CN (1) | CN103091487A (enExample) |
| AU (1) | AU2006313611B2 (enExample) |
| CA (1) | CA2629290C (enExample) |
| WO (1) | WO2007054714A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE533515C2 (sv) | 2008-04-16 | 2010-10-12 | Aamic Ab | Analysförfarande för samtidig analys av flera analyter |
| JP2010101703A (ja) * | 2008-10-22 | 2010-05-06 | Alfresa Pharma Corp | 免疫学的測定方法および測定用試薬キット |
| NZ625421A (en) * | 2009-09-24 | 2015-09-25 | Univ Monash | Testing device for identifying antigens and antibodies in biofluids |
| JP5723680B2 (ja) * | 2010-06-02 | 2015-05-27 | 積水化学工業株式会社 | 物質の測定方法 |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| GB201017447D0 (en) | 2010-10-15 | 2010-12-01 | Moorlodge Biotech Ventures Ltd | Assay device |
| JP5883645B2 (ja) * | 2011-12-28 | 2016-03-15 | デンカ生研株式会社 | 気泡吸着抑制方法 |
| DE102014007851B3 (de) | 2014-05-26 | 2015-11-12 | Medion Grifols Diagnostics Ag | Vorrichtung und Verfahren zur Bestimmung von Blutgruppenantigenen mit einem inkompletten Antikörper |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622871A (en) * | 1987-04-27 | 1997-04-22 | Unilever Patent Holdings B.V. | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents |
| US3951606A (en) * | 1974-05-17 | 1976-04-20 | Geomet, Inc. | Apparatus for prothrombin testing |
| JPS5341420A (en) * | 1976-09-29 | 1978-04-14 | Mochida Pharm Co Ltd | Immunochemically measuring methoa of hapten |
| US4233402A (en) * | 1978-04-05 | 1980-11-11 | Syva Company | Reagents and method employing channeling |
| GB2045431B (en) * | 1979-02-26 | 1983-04-20 | Technicon Instr | Immunoassay utilising two particulate reagents |
| US4391904A (en) * | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US4433059A (en) * | 1981-09-08 | 1984-02-21 | Ortho Diagnostic Systems Inc. | Double antibody conjugate |
| US4663278A (en) * | 1982-04-30 | 1987-05-05 | Syva Company | Agglutination dependent enzyme channeling immunoassay |
| US4459361A (en) * | 1982-06-04 | 1984-07-10 | Angenics, Inc. | Ligand assay with one or two particulate reagents and filter |
| GB8305197D0 (en) * | 1983-02-24 | 1983-03-30 | Amersham Int Plc | Assay methods |
| US4552839A (en) * | 1983-08-01 | 1985-11-12 | Syntex (U.S.A.) Inc. | Determination of analytes in particle-containing medium |
| US4745075A (en) * | 1984-09-06 | 1988-05-17 | Burroughs Wellcome Co. | Diagnostic test methods |
| EP0280559B1 (en) | 1987-02-27 | 1993-10-20 | EASTMAN KODAK COMPANY (a New Jersey corporation) | Agglutination immunoassay and kit for determination of a multivalent immune species using a buffered salt wash solution |
| JPS63305251A (ja) | 1987-06-05 | 1988-12-13 | Dai Ichi Pure Chem Co Ltd | ラテツクス凝集反応を利用する免疫学的測定方法 |
| IL85899A0 (en) | 1987-06-10 | 1988-09-30 | Miles Inc | Method,test device and test kit for separating labeled reagent in an immunometric binding assay |
| US4894347A (en) * | 1987-09-17 | 1990-01-16 | Agen Limited | Erythrocyte agglutination assay |
| US5086002A (en) * | 1987-09-07 | 1992-02-04 | Agen Biomedical, Ltd. | Erythrocyte agglutination assay |
| IL87768A (en) | 1987-09-17 | 1994-12-29 | Agen Ltd | Blood assay including erythrocyte agglutination and reagent for the assay comprising conjugate of erythrocyte binding molecule and analyte binding molecule |
| US4859612A (en) | 1987-10-07 | 1989-08-22 | Hygeia Sciences, Inc. | Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite |
| GB8800292D0 (en) | 1988-01-07 | 1988-02-10 | Int Inst Cellular Molecul Path | Assay method |
| US5202267A (en) * | 1988-04-04 | 1993-04-13 | Hygeia Sciences, Inc. | Sol capture immunoassay kit and procedure |
| US5334513A (en) * | 1988-05-17 | 1994-08-02 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
| US5573919A (en) * | 1988-06-02 | 1996-11-12 | Carter-Wallace | Assay using an absorbent material |
| GB8903046D0 (en) | 1989-02-10 | 1989-03-30 | Vale David R | Testing of liquids |
| US5583003A (en) * | 1989-09-25 | 1996-12-10 | Agen Limited | Agglutination assay |
| EP0494210A1 (en) * | 1989-09-25 | 1992-07-15 | Agen Limited | Agglutination assay |
| US6274325B1 (en) * | 1990-06-25 | 2001-08-14 | Boehringer Mannheim Gmbh | Method for carrying out a homogeneous-immunoassay based on agglutination |
| EP0556202B1 (en) | 1990-09-26 | 1997-05-14 | Akers Laboratories, Inc. | Improved ligand assay |
| US5231035A (en) * | 1991-01-11 | 1993-07-27 | Akers Research Corporation | Latex agglutination assay |
| US5972625A (en) * | 1991-05-06 | 1999-10-26 | The Regents Of The University Of California | Assays for inhibitors of leukocyte adhesion |
| JPH04350559A (ja) | 1991-05-28 | 1992-12-04 | Dai Ichi Pure Chem Co Ltd | 特異抗体の測定法 |
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| DK130991D0 (da) * | 1991-07-04 | 1991-07-04 | Immunodex K S | Polymere konjugater |
| DE4140142A1 (de) * | 1991-12-05 | 1993-06-09 | Boehringer Mannheim Gmbh, 6800 Mannheim, De | Multivalentes dextranreagenz zum einsatz in praezipitationstests |
| US5458852A (en) | 1992-05-21 | 1995-10-17 | Biosite Diagnostics, Inc. | Diagnostic devices for the controlled movement of reagents without membranes |
| JPH07506727A (ja) | 1992-05-22 | 1995-07-27 | アジェン・リミテッド | 凝集アッセイ用試薬 |
| TW239881B (enExample) * | 1992-12-22 | 1995-02-01 | Sienna Biotech Inc | |
| DE4309393A1 (de) * | 1993-03-23 | 1994-09-29 | Boehringer Mannheim Gmbh | Verringerung des Hook-Effekts in Immuntests mit teilchenförmigem Trägermaterial |
| ATE224053T1 (de) * | 1993-11-12 | 2002-09-15 | Inverness Medical Switzerland | Vorrichtung zum ablesen von teststreifen |
| JP3618909B2 (ja) * | 1996-07-09 | 2005-02-09 | 積水化学工業株式会社 | 免疫測定試薬及び免疫測定法 |
| JPH1026621A (ja) | 1996-07-12 | 1998-01-27 | Dai Ichi Pure Chem Co Ltd | イムノアッセイ法 |
| DE19637418A1 (de) * | 1996-09-13 | 1998-03-19 | Boehringer Mannheim Gmbh | Homogene Nachweisverfahren zur Bestimmung von Subpopulationen eines Analyten |
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| GB9821526D0 (en) * | 1998-10-02 | 1998-11-25 | Genosis Inc | Capture assay |
| GB9925461D0 (en) | 1999-10-27 | 1999-12-29 | Genosis Ltd | Assay device |
| JP3836648B2 (ja) * | 1999-12-03 | 2006-10-25 | 株式会社ミズホメディー | 検出装置及び検出方法 |
| WO2002004484A2 (en) * | 2000-07-07 | 2002-01-17 | Medmira Inc. | Hcv mosaic antigen composition |
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| US6759009B2 (en) * | 2001-05-04 | 2004-07-06 | Portascience Incorporated | Method and device for clotting time assay |
| GB0306098D0 (en) * | 2003-03-18 | 2003-04-23 | Platform Diagnostics Group Ltd | Sample testing device |
| US7195882B2 (en) | 2003-06-03 | 2007-03-27 | Roche Diagnostics Operations, Inc. | Monoclonal antibodies specific for buprenorphine and metabolites thereof |
| US7083936B2 (en) | 2003-08-01 | 2006-08-01 | Beckman Coulter, Inc. | Aminodextran compositions and conjugates and method of making and using them |
| JP4241301B2 (ja) | 2003-09-30 | 2009-03-18 | 和光純薬工業株式会社 | 免疫学的測定用試薬 |
| US20050079040A1 (en) * | 2003-10-09 | 2005-04-14 | Roger Perlstein | Lift system, lift retrofit system and method for installation of same |
| CN101019023A (zh) * | 2004-02-17 | 2007-08-15 | 比南股份有限公司 | 色谱排阻凝集测定及其使用方法 |
| US7642059B2 (en) * | 2005-09-07 | 2010-01-05 | Roche Diagnostics Operations, Inc. | Single receptor assays for immunosuppressive drugs |
-
2006
- 2006-11-13 JP JP2008539499A patent/JP5426881B2/ja not_active Expired - Fee Related
- 2006-11-13 EP EP13172799.2A patent/EP2674757A3/en not_active Withdrawn
- 2006-11-13 CN CN2012105747290A patent/CN103091487A/zh active Pending
- 2006-11-13 WO PCT/GB2006/004204 patent/WO2007054714A2/en not_active Ceased
- 2006-11-13 CA CA2629290A patent/CA2629290C/en not_active Expired - Fee Related
- 2006-11-13 US US12/093,440 patent/US9201065B2/en not_active Expired - Fee Related
- 2006-11-13 EP EP06808497A patent/EP1952158A2/en not_active Withdrawn
- 2006-11-13 AU AU2006313611A patent/AU2006313611B2/en not_active Ceased
-
2013
- 2013-05-07 JP JP2013097647A patent/JP2013174612A/ja active Pending
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