ZA202002415B - Detection of symmetrical dimethylarginine - Google Patents
Detection of symmetrical dimethylarginineInfo
- Publication number
- ZA202002415B ZA202002415B ZA2020/02415A ZA202002415A ZA202002415B ZA 202002415 B ZA202002415 B ZA 202002415B ZA 2020/02415 A ZA2020/02415 A ZA 2020/02415A ZA 202002415 A ZA202002415 A ZA 202002415A ZA 202002415 B ZA202002415 B ZA 202002415B
- Authority
- ZA
- South Africa
- Prior art keywords
- sdma
- detection
- sample
- symmetrical
- disclosure
- Prior art date
Links
- NWGZOALPWZDXNG-LURJTMIESA-N (2s)-5-(diaminomethylideneamino)-2-(dimethylamino)pentanoic acid Chemical compound CN(C)[C@H](C(O)=O)CCCNC(N)=N NWGZOALPWZDXNG-LURJTMIESA-N 0.000 title abstract 3
- YDGMGEXADBMOMJ-UHFFFAOYSA-N asymmetrical dimethylarginine Natural products CN(C)C(N)=NCCCC(N)C(O)=O YDGMGEXADBMOMJ-UHFFFAOYSA-N 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 150000001483 arginine derivatives Chemical class 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000002967 competitive immunoassay Methods 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762574592P | 2017-10-19 | 2017-10-19 | |
| US201762599117P | 2017-12-15 | 2017-12-15 | |
| PCT/US2018/056687 WO2019079707A1 (en) | 2017-10-19 | 2018-10-19 | SYMMETRIC DIMETHYLARGININE DETECTION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202002415B true ZA202002415B (en) | 2023-09-27 |
Family
ID=66170983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2020/02415A ZA202002415B (en) | 2017-10-19 | 2020-05-04 | Detection of symmetrical dimethylarginine |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11422136B2 (enExample) |
| EP (1) | EP3697499A4 (enExample) |
| JP (1) | JP7398366B2 (enExample) |
| KR (1) | KR20250034534A (enExample) |
| CN (1) | CN111246918B (enExample) |
| AU (1) | AU2018351349B2 (enExample) |
| CA (1) | CA3079011A1 (enExample) |
| MX (1) | MX2020003523A (enExample) |
| TW (1) | TWI831753B (enExample) |
| WO (1) | WO2019079707A1 (enExample) |
| ZA (1) | ZA202002415B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2313364T3 (da) * | 2008-08-07 | 2020-11-02 | Idexx Lab Inc | Fremgangsmåder til detektering af symmetrisk demethylarginin |
| US10775365B2 (en) * | 2015-02-20 | 2020-09-15 | Idexx Laboratories, Inc. | Homogenous immunoassay with compensation for background signal |
| CN111246918B (zh) | 2017-10-19 | 2024-06-14 | 艾德克斯实验室公司 | 对称二甲基精氨酸的检测 |
| US10745492B1 (en) * | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
| CA3152793A1 (en) | 2019-09-05 | 2021-03-11 | The Regents Of The University Of California | Noninvasive method to quantify kidney function and functional decline |
| CN113125697B (zh) * | 2019-12-31 | 2024-03-26 | 科美博阳诊断技术(上海)有限公司 | 一种睾酮均相化学发光检测试剂盒及其应用 |
| CA3179230A1 (en) | 2020-04-17 | 2021-10-21 | Idexx Laboratories, Inc. | Fluorescence quenching immunossay |
| EP4263383A4 (en) | 2020-12-17 | 2024-10-23 | Nephrosant, Inc. | KITS FOR STABILIZATION OF URINE SAMPLES |
| WO2025070448A1 (ja) * | 2023-09-26 | 2025-04-03 | 富士フイルム株式会社 | 対称性ジメチルアルギニンを測定するためのキットおよび対称性ジメチルアルギニンの測定方法 |
| WO2025205769A1 (ja) * | 2024-03-26 | 2025-10-02 | 富士フイルム株式会社 | α－アミラーゼと対称性ジメチルアルギニンとのコンジュゲート、およびその応用 |
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| DE3134787A1 (de) | 1981-09-02 | 1983-03-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Creatinin-antikoerper |
| IT1199088B (it) * | 1984-03-09 | 1988-12-30 | Miles Italiana | Saggio di legame specifico mediante impiego di anti-g6pdh come marcante |
| US4818703A (en) | 1985-10-23 | 1989-04-04 | Pizzolante John M | Stabilized alkaline picrate reagent for jaffe creatinine determination |
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| US5238652A (en) * | 1990-06-20 | 1993-08-24 | Drug Screening Systems, Inc. | Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques |
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| US6455288B1 (en) | 1993-04-08 | 2002-09-24 | Dade Behring Marburg Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
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| US6736957B1 (en) | 1997-10-16 | 2004-05-18 | Abbott Laboratories | Biosensor electrode mediators for regeneration of cofactors and process for using |
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| AU2452301A (en) | 1999-12-22 | 2001-07-03 | Research Foundation Of The State University Of New York, The | Protein methylarginine-specific antibodies |
| WO2002004465A1 (en) | 2000-07-06 | 2002-01-17 | Fal Diagnostics | Methods and kits for the detection of arginine compounds |
| WO2002004950A2 (en) | 2000-07-12 | 2002-01-17 | Werner Naser | Direct assessment of analyte to reference molecule ratios |
| DE10040904A1 (de) | 2000-08-18 | 2002-02-28 | Boeger Rainer H | Verfahren und Mittel zum Nachweis einer Wahrscheinlichkeit zukünftigen Fortschreitens von Gefässerkrankungen |
| US7241856B2 (en) | 2003-06-02 | 2007-07-10 | Pentron Clinical Technologies Llc | Dental resins, dental composite materials, and method of manufacture thereof |
| FR2824825B1 (fr) | 2001-05-15 | 2005-05-06 | Servier Lab | Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP4214271B2 (ja) | 2002-10-15 | 2009-01-28 | アークレイ株式会社 | クレアチニン測定用試験片 |
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| US10775365B2 (en) * | 2015-02-20 | 2020-09-15 | Idexx Laboratories, Inc. | Homogenous immunoassay with compensation for background signal |
| CN111246918B (zh) | 2017-10-19 | 2024-06-14 | 艾德克斯实验室公司 | 对称二甲基精氨酸的检测 |
| CN108469419A (zh) * | 2018-03-09 | 2018-08-31 | 山东泰邦生物制品有限公司 | 采用酶标仪免疫透射比浊法高通量检测IgG含量的方法 |
-
2018
- 2018-10-19 CN CN201880068370.5A patent/CN111246918B/zh active Active
- 2018-10-19 EP EP18868800.6A patent/EP3697499A4/en active Pending
- 2018-10-19 US US16/165,337 patent/US11422136B2/en active Active
- 2018-10-19 CA CA3079011A patent/CA3079011A1/en active Pending
- 2018-10-19 JP JP2020521964A patent/JP7398366B2/ja active Active
- 2018-10-19 MX MX2020003523A patent/MX2020003523A/es unknown
- 2018-10-19 AU AU2018351349A patent/AU2018351349B2/en active Active
- 2018-10-19 TW TW107136895A patent/TWI831753B/zh active
- 2018-10-19 KR KR1020257007101A patent/KR20250034534A/ko active Pending
- 2018-10-19 WO PCT/US2018/056687 patent/WO2019079707A1/en not_active Ceased
-
2020
- 2020-05-04 ZA ZA2020/02415A patent/ZA202002415B/en unknown
-
2022
- 2022-07-29 US US17/877,410 patent/US20230102277A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20190120856A1 (en) | 2019-04-25 |
| CN111246918B (zh) | 2024-06-14 |
| CN111246918A (zh) | 2020-06-05 |
| WO2019079707A1 (en) | 2019-04-25 |
| EP3697499A4 (en) | 2021-07-21 |
| CA3079011A1 (en) | 2019-04-25 |
| JP7398366B2 (ja) | 2023-12-14 |
| KR20200073259A (ko) | 2020-06-23 |
| TWI831753B (zh) | 2024-02-11 |
| BR112020007150A2 (pt) | 2020-09-24 |
| MX2020003523A (es) | 2020-07-22 |
| JP2021500551A (ja) | 2021-01-07 |
| US20230102277A1 (en) | 2023-03-30 |
| AU2018351349B2 (en) | 2025-08-14 |
| US11422136B2 (en) | 2022-08-23 |
| TW201923349A (zh) | 2019-06-16 |
| AU2018351349A1 (en) | 2020-04-23 |
| KR20250034534A (ko) | 2025-03-11 |
| EP3697499A1 (en) | 2020-08-26 |
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